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DFFA DNA fragmentation factor subunit alpha [ Sus scrofa (pig) ]

Gene ID: 100523126, updated on 8-Mar-2024

Summary

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Official Symbol
DFFAprovided by VGNC
Official Full Name
DNA fragmentation factor subunit alphaprovided by VGNC
Primary source
VGNC:VGNC:87265
See related
Ensembl:ENSSSCG00000003404
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in kidney (RPKM 12.5), liver (RPKM 12.5) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See DFFA in Genome Data Viewer
Location:
chromosome: 6
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (70725403..70736264, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (64658250..64669091, complement)

Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene apoptosis-inducing, TAF9-like domain 1 Neighboring gene cortistatin Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene castor zinc finger 1 Neighboring gene uncharacterized LOC110261094

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables deoxyribonuclease inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic DNA fragmentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA fragmentation factor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

    Range
    70725403..70736264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003127563.4 → XP_003127611.1  DNA fragmentation factor subunit alpha

    UniProtKB/TrEMBL
    A0A480V4D9, A0A4X1W9L0, A0A8D1YMK0, F1RHS7
    Related
    ENSSSCP00000003690.3, ENSSSCT00000003777.5
    Conserved Domains (2) summary
    pfam09033
    Location:100 → 263
    DFF-C; DNA Fragmentation factor 45kDa, C terminal domain
    cl02541
    Location:18 → 96
    CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
Nucleotide Protein
Heading Accession and Version

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