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scn2a sodium channel, voltage gated, type II alpha subunit [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486750, updated on 17-Aug-2024

Summary

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Official Symbol
scn2aprovided by Xenbase
Official Full Name
sodium channel, voltage gated, type II alpha subunitprovided by Xenbase
Primary source
Xenbase:XB-GENE-6447552
See related
Ensembl:ENSXETG00000021004
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
nav1.2; na(v)1.2
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Genomic context

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Location:
chromosome: 9
Exon count:
28
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (70262924..70424041, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (65192312..65258248, complement)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase 3 Neighboring gene cysteine-serine-rich nuclear protein 3 Neighboring gene U4 spliceosomal RNA Neighboring gene uncharacterized LOC116407830 Neighboring gene uncharacterized LOC116407655 Neighboring gene sodium channel, voltage gated, type III alpha subunit Neighboring gene solute carrier family 38 member 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of monoatomic ion channel complex IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sodium channel protein type 2 subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    70262924..70424041 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031893392.1 → XP_031749252.1  sodium channel protein type 2 subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A6I8T2N0, A0A8J1IUH8
    Related
    ENSXETP00000101489.2, ENSXETT00000098801.2
    Conserved Domains (5) summary
    cd13433
    Location:1446 → 1498
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1179 → 1454
    Ion_trans; Ion transport protein
    pfam06512
    Location:966 → 1175
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488 → 678
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1770 → 1817
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_031893391.1 → XP_031749251.1  sodium channel protein type 2 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A6I8T2N0, A0A8J1IXM1
    Conserved Domains (5) summary
    cd13433
    Location:1266 → 1318
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:999 → 1274
    Ion_trans; Ion transport protein
    pfam06512
    Location:786 → 995
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:316 → 498
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1590 → 1637
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein Strain
Heading Accession and Version

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