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CTSC cathepsin C [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100464355, updated on 8-Mar-2024

Summary

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Gene symbol
CTSC
Gene description
cathepsin C
Locus tag
PANDA_014484
See related
Ensembl:ENSAMEG00000015113
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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See CTSC in Genome Data Viewer
Location:
chromosome: 8
Exon count:
9
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 8 NC_048225.1 (41978945..42014762)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003218160.1 (698769..734223, complement)

Chromosome 8 - NC_048225.1Genomic Context describing neighboring genes Neighboring gene glutamate metabotropic receptor 5 Neighboring gene uncharacterized LOC117803351 Neighboring gene U6 spliceosomal RNA Neighboring gene RAB38, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sequence and de novo assembly of the giant panda genome. Li R, et al. Nature, 2010 Jan 21. PMID 20010809, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dipeptidyl peptidase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048225.1 Reference ASM200744v2 Primary Assembly

    Range
    41978945..42014762
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011232027.3 → XP_011230329.1  dipeptidyl peptidase 1 isoform X2

    UniProtKB/TrEMBL
    A0A7N5JVA9, A0A7N5KNF9
    Related
    ENSAMEP00000042438.1, ENSAMET00000037664.1
    Conserved Domains (1) summary
    pfam08773
    Location:26 → 106
    CathepsinC_exc; Cathepsin C exclusion domain

  2. XM_002925012.4 → XP_002925058.1  dipeptidyl peptidase 1 isoform X1

    See identical proteins and their annotated locations for XP_002925058.1

    UniProtKB/TrEMBL
    A0A7N5JN05, D2HR89
    Related
    ENSAMEP00000015940.1, ENSAMET00000016605.2
    Conserved Domains (2) summary
    cd02621
    Location:229 → 458
    Peptidase_C1A_CathepsinC; Cathepsin C; also known as Dipeptidyl Peptidase I (DPPI), an atypical papain-like cysteine peptidase with chloride dependency and dipeptidyl aminopeptidase activity, resulting from its tetrameric structure which limits substrate access. Each subunit of ...
    pfam08773
    Location:26 → 138
    CathepsinC_exc; Cathepsin C exclusion domain
Nucleotide Protein
Heading Accession and Version

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