BRCA1 BRCA1 DNA repair associated [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: BRCA1
Gene description: BRCA1 DNA repair associated
Locus tag: CR201_G0051415
See related: Ensembl:ENSPPYG00000008363
Gene type: protein coding
RefSeq status: MODEL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 19

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	19	NC_072004.2 (73303988..73401395, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	Unplaced Scaffold	NW_026537337.1 (13570400..13666034, complement)

Chromosome 19 - NC_072004.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

GDB:454458 (e-PCR)
- UniSTS:157440

GDB:454466 (e-PCR)
- UniSTS:157442

PMC280658P1 (e-PCR)
- UniSTS:272396

PMC280658P2 (e-PCR)
- UniSTS:272397

D10S275 (e-PCR)
- UniSTS:147992

RH79896 (e-PCR)
- UniSTS:90392

PMC139147P1 (e-PCR)
- UniSTS:270874

PMC13918P1 (e-PCR)
- UniSTS:270877

NoName (e-PCR)
- UniSTS:482866

D17S1322 (e-PCR)
- UniSTS:150079

D17S1323 (e-PCR)
- UniSTS:150080

SHGC-34684 (e-PCR)
- UniSTS:3138

BRCA1_4046 (e-PCR)
- UniSTS:464465

L18426 (e-PCR)
- UniSTS:34648

PMC110706P1 (e-PCR)
- UniSTS:270193

PMC310899P11 (e-PCR)
- UniSTS:272801

PMC310899P12 (e-PCR)
- UniSTS:272802

PMC310899P2 (e-PCR)
- UniSTS:272804

PMC310899P3 (e-PCR)
- UniSTS:272805

PMC310899P5 (e-PCR)
- UniSTS:272806

PMC310899P6 (e-PCR)
- UniSTS:272807

GDB:626829 (e-PCR)
- UniSTS:158401

G10044 (e-PCR)
- UniSTS:1986

GDB:626905 (e-PCR)
- UniSTS:158402

RH70206 (e-PCR)
- UniSTS:75226

D17S1198 (e-PCR)
- UniSTS:56291

GDB:388557 (e-PCR)
- UniSTS:157159

GDB:388674 (e-PCR)
- UniSTS:157161

GDB:389033 (e-PCR)
- UniSTS:157163

GDB:389047 (e-PCR)
- UniSTS:157164

GDB:389054 (e-PCR)
- UniSTS:157165

GDB:631944 (e-PCR)
- UniSTS:158446

GDB:391358 (e-PCR)
- UniSTS:157167

GDB:391365 (e-PCR)
- UniSTS:157168

GDB:454227 (e-PCR)
- UniSTS:157424

GDB:391372 (e-PCR)
- UniSTS:157169

GDB:454278 (e-PCR)
- UniSTS:157425

GDB:391818 (e-PCR)
- UniSTS:157170

GDB:454349 (e-PCR)
- UniSTS:157426

GDB:391825 (e-PCR)
- UniSTS:157171

GDB:454353 (e-PCR)
- UniSTS:157427

GDB:391832 (e-PCR)
- UniSTS:157172

GDB:454372 (e-PCR)
- UniSTS:157428

GDB:391839 (e-PCR)
- UniSTS:157173

GDB:454381 (e-PCR)
- UniSTS:157429

GDB:391846 (e-PCR)
- UniSTS:157174

GDB:454417 (e-PCR)
- UniSTS:157430

GDB:391853 (e-PCR)
- UniSTS:157175

GDB:454421 (e-PCR)
- UniSTS:157431

GDB:391860 (e-PCR)
- UniSTS:157176

GDB:454425 (e-PCR)
- UniSTS:157432

GDB:391867 (e-PCR)
- UniSTS:157177

GDB:454429 (e-PCR)
- UniSTS:157433

GDB:391874 (e-PCR)
- UniSTS:157178

GDB:454433 (e-PCR)
- UniSTS:157434

GDB:391881 (e-PCR)
- UniSTS:157179

GDB:454437 (e-PCR)
- UniSTS:157435

GDB:454441 (e-PCR)
- UniSTS:157436

GDB:454446 (e-PCR)
- UniSTS:157437

GDB:454450 (e-PCR)
- UniSTS:157438

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chordate embryonic development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in dosage compensation by inactivation of X chromosome	IEA Inferred from Electronic Annotation more info	PubMed
involved_in double-strand break repair via homologous recombination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of BRCA1-A complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of BRCA1-BARD1 complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: breast cancer type 1 susceptibility protein

Names: breast cancer type 1 susceptibility protein homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_072004.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

73303988..73401395 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054546460.2 → XP_054402435.2 breast cancer type 1 susceptibility protein isoform X5

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546474.2 → XP_054402449.2 breast cancer type 1 susceptibility protein isoform X15

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546475.2 → XP_054402450.2 breast cancer type 1 susceptibility protein isoform X16

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546453.2 → XP_054402428.2 breast cancer type 1 susceptibility protein isoform X1

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546477.2 → XP_054402452.2 breast cancer type 1 susceptibility protein isoform X19

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_063718833.1 → XP_063574903.1 breast cancer type 1 susceptibility protein isoform X18

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_063718829.1 → XP_063574899.1 breast cancer type 1 susceptibility protein isoform X2

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_009251698.4 → XP_009249973.3 breast cancer type 1 susceptibility protein isoform X1

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_063718834.1 → XP_063574904.1 breast cancer type 1 susceptibility protein isoform X21

UniProtKB/TrEMBL

A0A2J8REM1
XM_003778832.4 → XP_003778880.3 breast cancer type 1 susceptibility protein isoform X1

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546473.2 → XP_054402448.2 breast cancer type 1 susceptibility protein isoform X14

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546465.2 → XP_054402440.2 breast cancer type 1 susceptibility protein isoform X9

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546472.2 → XP_054402447.2 breast cancer type 1 susceptibility protein isoform X13

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_009251711.4 → XP_009249986.3 breast cancer type 1 susceptibility protein isoform X12

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546471.2 → XP_054402446.2 breast cancer type 1 susceptibility protein isoform X12

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546457.2 → XP_054402432.2 breast cancer type 1 susceptibility protein isoform X4

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546458.2 → XP_054402433.2 breast cancer type 1 susceptibility protein isoform X4

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546463.2 → XP_054402438.2 breast cancer type 1 susceptibility protein isoform X7

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_024235546.3 → XP_024091314.2 breast cancer type 1 susceptibility protein isoform X3

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_024235547.3 → XP_024091315.2 breast cancer type 1 susceptibility protein isoform X2

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_009251710.4 → XP_009249985.3 breast cancer type 1 susceptibility protein isoform X11

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546455.2 → XP_054402430.2 breast cancer type 1 susceptibility protein isoform X3

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546454.2 → XP_054402429.2 breast cancer type 1 susceptibility protein isoform X2

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546468.2 → XP_054402443.2 breast cancer type 1 susceptibility protein isoform X10

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_009251699.4 → XP_009249974.3 breast cancer type 1 susceptibility protein isoform X1

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546466.2 → XP_054402441.2 breast cancer type 1 susceptibility protein isoform X10

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546464.2 → XP_054402439.2 breast cancer type 1 susceptibility protein isoform X8

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546462.2 → XP_054402437.2 breast cancer type 1 susceptibility protein isoform X6

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_009251700.4 → XP_009249975.3 breast cancer type 1 susceptibility protein isoform X1

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546482.2 → XP_054402457.1 breast cancer type 1 susceptibility protein isoform X23

UniProtKB/TrEMBL

A0A2J8REM1
XM_054546481.2 → XP_054402456.1 breast cancer type 1 susceptibility protein isoform X22

UniProtKB/TrEMBL

A0A2J8REM1
XM_054546480.2 → XP_054402455.1 breast cancer type 1 susceptibility protein isoform X21

UniProtKB/TrEMBL

A0A2J8REM1
XM_054546478.2 → XP_054402453.1 breast cancer type 1 susceptibility protein isoform X20

UniProtKB/TrEMBL

A0A2J8REM1, A0A2J8REN5, A0A8I5YRG9
XM_054546479.2 → XP_054402454.1 breast cancer type 1 susceptibility protein isoform X20

UniProtKB/TrEMBL

A0A2J8REM1, A0A2J8REN5, A0A8I5YRG9
XM_063718831.1 → XP_063574901.1 breast cancer type 1 susceptibility protein isoform X10

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_054546469.2 → XP_054402444.2 breast cancer type 1 susceptibility protein isoform X10

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_063718832.1 → XP_063574902.1 breast cancer type 1 susceptibility protein isoform X17

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349
XM_063718830.1 → XP_063574900.1 breast cancer type 1 susceptibility protein isoform X10

UniProtKB/TrEMBL

A0A2J8REL0, A0A8I5U349