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SH2D3C SH2 domain containing 3C [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100437299, updated on 3-Apr-2024

Summary

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Gene symbol
SH2D3C
Gene description
SH2 domain containing 3C
Locus tag
CR201_G0027628
See related
Ensembl:ENSPPYG00000019630
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 13 NC_071998.2 (119061308..119108080, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 9 NC_071994.1 (103454473..103501311, complement)

Chromosome 13 - NC_071998.2Genomic Context describing neighboring genes Neighboring gene peptidyl-tRNA hydrolase 1 homolog Neighboring gene cilia and flagella associated protein 157 Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene torsin family 2 member A Neighboring gene uncharacterized LOC129048022 Neighboring gene cyclin dependent kinase 9 Neighboring gene folylpolyglutamate synthase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2 domain-containing protein 3C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071998.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    119061308..119108080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054520677.2 → XP_054376652.1  SH2 domain-containing protein 3C isoform X1

    UniProtKB/TrEMBL
    A0A8I5SZ97

  2. XM_063714449.1 → XP_063570519.1  SH2 domain-containing protein 3C isoform X2

    UniProtKB/TrEMBL
    A0A2J8UK75, A0A8I5U5S2

  3. XM_002820236.5 → XP_002820282.1  SH2 domain-containing protein 3C isoform X3

    UniProtKB/TrEMBL
    A0A2J8UK97, A0A6D2XIR9, H2PTG7
    Related
    ENSPPYP00000021998.2
    Conserved Domains (2) summary
    cd10337
    Location:56 → 190
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:428 → 597
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  4. XM_054520679.2 → XP_054376654.1  SH2 domain-containing protein 3C isoform X6

    UniProtKB/TrEMBL
    A0A2J8UK92

  5. XM_002820235.4 → XP_002820281.1  SH2 domain-containing protein 3C isoform X4

    UniProtKB/TrEMBL
    A0A2J8UK61, A0A8I5U4P8
    Related
    ENSPPYP00000044730.1
    Conserved Domains (2) summary
    cd10337
    Location:55 → 189
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:427 → 596
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  6. XM_054520678.2 → XP_054376653.1  SH2 domain-containing protein 3C isoform X5

    UniProtKB/TrEMBL
    A0A2J8UK63

  7. XM_024252612.3 → XP_024108380.1  SH2 domain-containing protein 3C isoform X6

    UniProtKB/TrEMBL
    A0A2J8UK92
    Conserved Domains (1) summary
    cl02485
    Location:231 → 400
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein
Heading Accession and Version

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