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INSIG2 insulin induced gene 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100355934, updated on 8-Mar-2024

Summary

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Gene symbol
INSIG2
Gene description
insulin induced gene 2
See related
Ensembl:ENSOCUG00000005251
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See INSIG2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 7 NC_067380.1 (108672455..108697099)

Chromosome 7 - NC_067380.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 93 Neighboring gene uncharacterized LOC103348741 Neighboring gene uncharacterized LOC108176830 Neighboring gene engrailed homeobox 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067380.1 Chromosome 7 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in SREBP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SREBP-SCAP complex retention in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SREBP-SCAP-Insig complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-induced gene 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067380.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    108672455..108697099
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051848744.1 → XP_051704704.1  insulin-induced gene 2 protein isoform X1

    UniProtKB/TrEMBL
    G1SNI6

  2. XM_008258482.3 → XP_008256704.1  insulin-induced gene 2 protein isoform X1

    See identical proteins and their annotated locations for XP_008256704.1

    UniProtKB/TrEMBL
    G1SNI6
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  3. XM_008258481.3 → XP_008256703.1  insulin-induced gene 2 protein isoform X1

    See identical proteins and their annotated locations for XP_008256703.1

    UniProtKB/TrEMBL
    G1SNI6
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  4. XM_017342795.2 → XP_017198284.1  insulin-induced gene 2 protein isoform X2

    Conserved Domains (1) summary
    pfam07281
    Location:1 → 103
    INSIG; Insulin-induced protein (INSIG)

  5. XM_002712385.4 → XP_002712431.1  insulin-induced gene 2 protein isoform X1

    See identical proteins and their annotated locations for XP_002712431.1

    UniProtKB/TrEMBL
    G1SNI6
    Related
    ENSOCUP00000004552.3
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)
Nucleotide Protein
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