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adam8a ADAM metallopeptidase domain 8a [ Ictalurus punctatus (channel catfish) ]

Gene ID: 100303713, updated on 12-Sep-2024

Summary

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Gene symbol
adam8a
Gene description
ADAM metallopeptidase domain 8a
See related
EnsemblRapid:ENSIPUG00020010053
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ictalurus punctatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes; Ictaluridae; Ictalurus
Also known as
adam8
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: 3
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_03 current Coco_2.0 (GCF_001660625.3) 3 NC_030418.2 (23053620..23061893, complement)
101 previous assembly IpCoco_1.2 (GCF_001660625.2) 3 NC_030418.1 (14007703..14015933)

Chromosome 3 - NC_030418.2Genomic Context describing neighboring genes Neighboring gene ER lipid raft associated 1 Neighboring gene sperm flagellar 1 Neighboring gene zinc finger protein 511 Neighboring gene muscle segment homeobox 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Channel catfish (Ictalurus punctatus Rafinesque, 1818) CD156a (ADAM metallopeptidase domain 8): cDNA clone, characterization and expression in tissues. Yeh HY, et al. Vet Immunol Immunopathol, 2009 Dec 15. PMID 19501921
  2. Transcriptome Display During Testicular Differentiation of Channel Catfish (Ictalurus punctatus) as Revealed by RNA-Seq Analysis. Zeng Q, et al. Biol Reprod, 2016 Jul. PMID 27307075, Free PMC Article
  3. Efficient assembly and annotation of the transcriptome of catfish by RNA-Seq analysis of a doubled haploid homozygote. Liu S, et al. BMC Genomics, 2012 Nov 5. PMID 23127152, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cellular extravasation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disintegrin and metalloproteinase domain-containing protein 8a
Names
a disintegrin and metalloproteinase domain 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001200069.1 → NP_001186998.1  disintegrin and metalloproteinase domain-containing protein 8a precursor

    See identical proteins and their annotated locations for NP_001186998.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ594762
    UniProtKB/TrEMBL
    B9VR87
    Related
    ENSIPUP00020018615.1, ENSIPUT00020022341.1
    Conserved Domains (6) summary
    smart00050
    Location:415 → 489
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:491 → 610
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:200 → 396
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
    pfam01421
    Location:200 → 398
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:44 → 159
    Pep_M12B_propep; Reprolysin family propeptide
    pfam07974
    Location:623 → 646
    EGF_2; EGF-like domain

RefSeqs of Annotated Genomes: GCF_001660625.3-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Coco_2.0 Primary Assembly

Genomic

  1. NC_030418.2 Reference Coco_2.0 Primary Assembly

    Range
    23053620..23061893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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