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ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 [ Taeniopygia guttata (zebra finch) ]

Gene ID: 100218467, updated on 13-Aug-2024

Summary

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Gene symbol
ARHGEF18
Gene description
Rho/Rac guanine nucleotide exchange factor 18
See related
Ensembl:ENSTGUG00000000416
Gene type
protein coding
RefSeq status
MODEL
Organism
Taeniopygia guttata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Taeniopygia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 28
Exon count:
23
Annotation release Status Assembly Chr Location
106 current bTaeGut1.4.pri (GCF_003957565.2) 28 NC_044240.2 (3114819..3146005)
105 previous assembly bTaeGut2.pat.W.v2 (GCF_008822105.2) 28 NC_045026.1 (1995619..2046256)

Chromosome 28 - NC_044240.2Genomic Context describing neighboring genes Neighboring gene unconventional SNARE in the ER 1 Neighboring gene insulin receptor Neighboring gene ectoderm-neural cortex protein 1 Neighboring gene uncharacterized LOC121468073 Neighboring gene peroxisomal biogenesis factor 11 gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 18

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Taeniopygia guttata Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bTaeGut1.4.pri Primary Assembly

Genomic

  1. NC_044240.2 Reference bTaeGut1.4.pri Primary Assembly

    Range
    3114819..3146005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012571251.4 → XP_012426705.3  rho guanine nucleotide exchange factor 18 isoform X2

    Conserved Domains (3) summary
    cd00160
    Location:102 → 296
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd15794
    Location:336 → 454
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
    pfam17380
    Location:663 → 811
    DUF5401; Family of unknown function (DUF5401)

  2. XM_030256530.3 → XP_030112390.3  rho guanine nucleotide exchange factor 18 isoform X2

    Conserved Domains (3) summary
    cd00160
    Location:102 → 296
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd15794
    Location:336 → 454
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
    pfam17380
    Location:663 → 811
    DUF5401; Family of unknown function (DUF5401)

  3. XM_012571252.4 → XP_012426706.3  rho guanine nucleotide exchange factor 18 isoform X2

    Conserved Domains (3) summary
    cd00160
    Location:102 → 296
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd15794
    Location:336 → 454
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
    pfam17380
    Location:663 → 811
    DUF5401; Family of unknown function (DUF5401)

  4. XM_030256531.3 → XP_030112391.3  rho guanine nucleotide exchange factor 18 isoform X2

    Conserved Domains (3) summary
    cd00160
    Location:102 → 296
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd15794
    Location:336 → 454
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
    pfam17380
    Location:663 → 811
    DUF5401; Family of unknown function (DUF5401)

  5. XM_041710907.1 → XP_041566841.1  rho guanine nucleotide exchange factor 18 isoform X1

    Conserved Domains (4) summary
    COG4372
    Location:744 → 1050
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:207 → 401
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd15794
    Location:441 → 559
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
    pfam17380
    Location:768 → 916
    DUF5401; Family of unknown function (DUF5401)
Nucleotide Protein
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