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tusc4 Tumor suppressor candidate 4 [ Salmo salar (Atlantic salmon) ]

Gene ID: 100195496, updated on 30-Nov-2023

Summary

Gene symbol
tusc4
Gene description
Tumor suppressor candidate 4
See related
Ensembl:ENSSSAG00000039735
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Salmo salar
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
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Genomic context

Location:
chromosome: ssa12
Exon count:
14
Annotation release Status Assembly Chr Location
102 current Ssal_v3.1 (GCF_905237065.1) ssa12 NC_059453.1 (84237608..84246594)
100 previous assembly ICSASG_v2 (GCF_000233375.1) ssa12 NC_027311.1 (75683799..75692688)

Chromosome ssa12 - NC_059453.1Genomic Context describing neighboring genes Neighboring gene twinfilin-2-like Neighboring gene cytokine-inducible SH2-containing protein Neighboring gene HemK methyltransferase family member 1 Neighboring gene ras association domain-containing protein 1 Neighboring gene Tumor suppressor candidate 2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of autophagy IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of GATOR1 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
Tumor suppressor candidate 4; tumor suppressor candidate 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001140525.1NP_001133997.1  Tumor suppressor candidate 4

    See identical proteins and their annotated locations for NP_001133997.1

    Status: PROVISIONAL

    Source sequence(s)
    BT046019
    UniProtKB/TrEMBL
    B5X4Q0
    Related
    ENSSSAP00000030631.2, ENSSSAT00000055931.2
    Conserved Domains (1) summary
    cl24021
    Location:6369
    NPR3; Nitrogen Permease regulator of amino acid transport activity 3

RefSeqs of Annotated Genomes: Salmo salar Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ssal_v3.1

Genomic

  1. NC_059453.1 Reference Ssal_v3.1

    Range
    84237608..84246594
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014133661.2XP_013989136.1  tumor suppressor candidate 4 isoform X4

    UniProtKB/TrEMBL
    A0A1S3LDV1
    Conserved Domains (1) summary
    cl24021
    Location:4296
    NPR3; Nitrogen Permease regulator of amino acid transport activity 3
  2. XM_014133660.2XP_013989135.1  tumor suppressor candidate 4 isoform X4

    UniProtKB/TrEMBL
    A0A1S3LDV1
    Related
    ENSSSAP00000030660.2, ENSSSAT00000055961.2
    Conserved Domains (1) summary
    cl24021
    Location:4296
    NPR3; Nitrogen Permease regulator of amino acid transport activity 3
  3. XM_045690432.1XP_045546388.1  tumor suppressor candidate 4 isoform X1

  4. XM_014133658.2XP_013989133.1  tumor suppressor candidate 4 isoform X2

    UniProtKB/TrEMBL
    A0A1S3LDV2
    Conserved Domains (1) summary
    cl24021
    Location:6354
    NPR3; Nitrogen Permease regulator of amino acid transport activity 3
  5. XM_045690433.1XP_045546389.1  tumor suppressor candidate 4 isoform X3

    Related
    ENSSSAP00000125723.1, ENSSSAT00000216628.1