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ERLIN2 ER lipid raft associated 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100173353, updated on 26-Mar-2024

Summary

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Gene symbol
ERLIN2
Gene description
ER lipid raft associated 2
Locus tag
CR201_G0033401
See related
Ensembl:ENSPPYG00000018510
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Also known as
SPFH2; Erlin-2
Orthologs
human mouse all
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Genomic context

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See ERLIN2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 7 NC_071992.2 (39690745..39711453)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 8 NC_071993.1 (40972243..40991567)

Chromosome 7 - NC_071992.2Genomic Context describing neighboring genes Neighboring gene zinc finger protein 703 Neighboring gene uncharacterized LOC112134703 Neighboring gene STING ER exit protein-like Neighboring gene pyridoxal phosphate binding protein Neighboring gene adhesion G protein-coupled receptor A2 Neighboring gene BRF2 RNA polymerase III transcription initiation factor subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp469K0819

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in SREBP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
erlin-2
Names
SPFH domain-containing protein 2
endoplasmic reticulum lipid raft-associated protein 2
stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001132900.1 → NP_001126372.1  erlin-2

    See identical proteins and their annotated locations for NP_001126372.1

    Status: PROVISIONAL

    Source sequence(s)
    CR860193
    UniProtKB/Swiss-Prot
    Q5R7C5, Q5RBV6
    UniProtKB/TrEMBL
    A0A2J8TPB0, A0A2J8TPJ8
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071992.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    39690745..39711453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009243698.3 → XP_009241973.2  erlin-2 isoform X2

  2. XM_009243695.4 → XP_009241970.1  erlin-2 isoform X1

    See identical proteins and their annotated locations for XP_009241970.1

    UniProtKB/Swiss-Prot
    Q5R7C5, Q5RBV6
    UniProtKB/TrEMBL
    A0A2J8TPB0, A0A2J8TPJ8
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  3. XM_009243696.4 → XP_009241971.1  erlin-2 isoform X1

    See identical proteins and their annotated locations for XP_009241971.1

    UniProtKB/Swiss-Prot
    Q5R7C5, Q5RBV6
    UniProtKB/TrEMBL
    A0A2J8TPB0, A0A2J8TPJ8
    Related
    ENSPPYP00000043710.1
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  4. XM_009243697.4 → XP_009241972.1  erlin-2 isoform X1

    See identical proteins and their annotated locations for XP_009241972.1

    UniProtKB/Swiss-Prot
    Q5R7C5, Q5RBV6
    UniProtKB/TrEMBL
    A0A2J8TPB0, A0A2J8TPJ8
    Conserved Domains (1) summary
    cd03406
    Location:16 → 308
    SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  5. XM_054560954.2 → XP_054416929.1  erlin-2 isoform X3

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5R7C5.1 GenPept UniProtKB/Swiss-Prot:Q5R7C5

Gene LinkOut

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