CCL2 C-C motif chemokine ligand 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: CCL2
Gene description: C-C motif chemokine ligand 2
Locus tag: CR201_G0033746
See related: Ensembl:ENSPPYG00000008169
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
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Genomic context

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	19	NC_072004.2 (48262025..48295317)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	17	NC_072002.1 (49744454..49777737)

Chromosome 19 - NC_072004.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D17S1269 (e-PCR)
- UniSTS:149810

CCL2_498 (e-PCR)
- UniSTS:277056

GDB:607769 (e-PCR)
- UniSTS:158283

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in eosinophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-C motif chemokine 2

Names: chemokine (C-C motif) ligand 2; small-inducible cytokine A2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001132340.2 → NP_001125812.1 C-C motif chemokine 2 precursor

See identical proteins and their annotated locations for NP_001125812.1

Status: PROVISIONAL

Source sequence(s)

CR859186

UniProtKB/Swiss-Prot

Q5RA36

Related

ENSPPYP00000009183.2, ENSPPYT00000009554.3

Conserved Domains (1) summary

cd00272
Location:34 → 91

Chemokine_CC; Chemokine_CC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g. ...

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_072004.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

48262025..48295317

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054535171.2 → XP_054391146.1 C-C motif chemokine 2 isoform X1
XM_002827248.3 → XP_002827294.1 C-C motif chemokine 2 isoform X2

UniProtKB/TrEMBL

A0A2J8TNP9, A0A6D2XSH2, H2NTB7

Related

ENSPPYP00000009186.1

Conserved Domains (1) summary

pfam00048
Location:30 → 87

IL8; Small cytokines (intecrine/chemokine), interleukin-8 like