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LAMA2 laminin subunit alpha 2 [ Sus scrofa (pig) ]

Gene ID: 100154420, updated on 17-Aug-2024

Summary

Official Symbol
LAMA2provided by VGNC
Official Full Name
laminin subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:101493
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in subcutaneous adipose (RPKM 58.3), heart (RPKM 33.5) and 7 other tissues See more
Orthologs
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Genomic context

Location:
chromosome: 1
Exon count:
65
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (33765412..34359741, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (37284919..37545503, complement)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106508849 Neighboring gene Rho GTPase activating protein 18 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene putative nucleoside diphosphate kinase Neighboring gene uncharacterized LOC102159312

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
LOW QUALITY PROTEIN: laminin subunit alpha-2
Names
laminin, alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    33765412..34359741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021084463.1XP_020940122.1  LOW QUALITY PROTEIN: laminin subunit alpha-2

    UniProtKB/TrEMBL
    A0A8D0SWL8
    Conserved Domains (11) summary
    smart00136
    Location:37289
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:9721016
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:12341369
    LamB; Laminin B domain
    cd00055
    Location:922968
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:29303082
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00053
    Location:10651113
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:27822910
    Laminin_G_1; Laminin G domain
    pfam06009
    Location:20252161
    Laminin_II; Laminin Domain II
    pfam00052
    Location:587727
    Laminin_B; Laminin B (Domain IV)
    pfam06008
    Location:15991857
    Laminin_I; Laminin Domain I
    cl25732
    Location:18202133
    SMC_N; RecF/RecN/SMC N terminal domain