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lrch2 leucine-rich repeats and calponin homology (CH) domain containing 2 [ Danio rerio (zebrafish) ]

Gene ID: 100150488, updated on 27-Mar-2024

Summary

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Official Symbol
lrch2provided by ZNC
Official Full Name
leucine-rich repeats and calponin homology (CH) domain containing 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-080114-1
See related
AllianceGenome:ZFIN:ZDB-GENE-080114-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:eu904
Summary
Orthologous to human LRCH2 (leucine rich repeats and calponin homology domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See lrch2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (37130477..37247696, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (36530874..36647516, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene transgelin 2 Neighboring gene interleukin 13 receptor, alpha 2 Neighboring gene uncharacterized LOC103911092 Neighboring gene si:dkey-17o15.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development. Shestopalov IA, et al. Nat Chem Biol, 2012 Jan 29. PMID 22286130, Free PMC Article
  2. Evolution of Class I cytokine receptors. Liongue C, et al. BMC Evol Biol, 2007 Jul 18. PMID 17640376, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
leucine-rich repeat and calponin homology domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    37130477..37247696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021476551.1 → XP_021332226.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9Q9J5
    Conserved Domains (3) summary
    smart00033
    Location:620 → 693
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_021476550.1 → XP_021332225.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9QA99
    Conserved Domains (3) summary
    smart00033
    Location:633 → 706
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  3. XM_021476549.1 → XP_021332224.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9Q494
    Conserved Domains (3) summary
    smart00033
    Location:643 → 716
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  4. XM_021476548.1 → XP_021332223.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PYU6
    Conserved Domains (3) summary
    smart00033
    Location:656 → 729
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394595.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    376928..491935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021471636.1 → XP_021327311.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9QA99
    Conserved Domains (3) summary
    smart00033
    Location:633 → 706
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_021471637.1 → XP_021327312.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9Q9J5
    Conserved Domains (3) summary
    smart00033
    Location:620 → 693
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395241.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    22561..131952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474038.1 → XP_021329713.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PRQ2
    Conserved Domains (3) summary
    smart00033
    Location:620 → 693
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_001921894.6 → XP_001921929.5  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M1QLI1
    Conserved Domains (3) summary
    smart00033
    Location:633 → 706
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  3. XM_009301687.3 → XP_009299962.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M3ASK2
    Conserved Domains (3) summary
    smart00033
    Location:643 → 716
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  4. XM_009301685.3 → XP_009299960.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AZV0
    Conserved Domains (3) summary
    smart00033
    Location:656 → 729
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

Reference GRCz11 ALT_DRER_TU_3

Genomic

  1. NW_018395375.1 Reference GRCz11 ALT_DRER_TU_3

    Range
    22222..139441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474591.1 → XP_021330266.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8M9Q9J5
    Conserved Domains (3) summary
    smart00033
    Location:620 → 693
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  2. XM_021474590.1 → XP_021330265.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8M9QA99
    Conserved Domains (3) summary
    smart00033
    Location:633 → 706
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  3. XM_021474589.1 → XP_021330264.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9Q494
    Conserved Domains (3) summary
    smart00033
    Location:643 → 716
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]

  4. XM_021474588.1 → XP_021330263.1  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PYU6
    Conserved Domains (3) summary
    smart00033
    Location:656 → 729
    CH; Calponin homology domain
    COG4886
    Location:100 → 298
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:57 → 76
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein Strain
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