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zp3e zona pellucida glycoprotein 3e [ Danio rerio (zebrafish) ]

Gene ID: 100126104, updated on 12-Sep-2024

Summary

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Official Symbol
zp3eprovided by ZNC
Official Full Name
zona pellucida glycoprotein 3eprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071004-38
See related
Ensembl:ENSDARG00000016908 AllianceGenome:ZFIN:ZDB-GENE-071004-38
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zpc3; zgc:171779
Summary
Predicted to enable acrosin binding activity. Predicted to be involved in binding activity of sperm to zona pellucida; egg coat formation; and positive regulation of acrosome reaction. Predicted to be located in extracellular space and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 3
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (31877325..31879219, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (31745611..31747505, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 3 Neighboring gene LIM domain containing 2 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box helicase 42 Neighboring gene STE20 related adaptor alpha Neighboring gene ring finger protein 113A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Bioinformatic analyses of zona pellucida genes in vertebrates and their expression in Nile tilapia. Wu T, et al. Fish Physiol Biochem, 2018 Apr. PMID 29307115
  2. Detection of biomarkers to differentiate endocrine disruption from hepatotoxicity in zebrafish (Danio rerio) using proteomics. Ayobahan SU, et al. Chemosphere, 2020 Feb. PMID 31726584
  3. A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. Ayobahan SU, et al. Sci Rep, 2019 Apr 29. PMID 31036921, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables acrosin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of egg coat IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in binding of sperm to zona pellucida IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in egg coat formation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of acrosome reaction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in egg coat IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zona pellucida glycoprotein 3e
Names
zona pellucida glycoprotein 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109833.1 → NP_001103303.1  zona pellucida glycoprotein 3e precursor

    See identical proteins and their annotated locations for NP_001103303.1

    Status: PROVISIONAL

    Source sequence(s)
    BC151978
    UniProtKB/TrEMBL
    A7MBZ6
    Related
    ENSDARP00000070667.2, ENSDART00000076189.3
    Conserved Domains (2) summary
    smart00241
    Location:127 → 384
    ZP; Zona pellucida (ZP) domain
    pfam00100
    Location:264 → 382
    Zona_pellucida; Zona pellucida-like domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    31877325..31879219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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