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mmp15b matrix metallopeptidase 15b [ Oryzias latipes (Japanese medaka) ]

Gene ID: 100125423, updated on 12-Sep-2024

Summary

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Gene symbol
mmp15b
Gene description
matrix metallopeptidase 15b
See related
EnsemblRapid:ENSORLG00000015418
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Oryzias latipes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
Also known as
mmp15; olmt2-mmp
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
103 current ASM223467v1 (GCF_002234675.1) 3 NC_019861.2 (34703105..34733891)
102 previous assembly ASM31367v1 (GCF_000313675.1) 3 NC_019861.1 (34263650..34294682)

Chromosome 3 - NC_019861.2Genomic Context describing neighboring genes Neighboring gene adhesion G-protein coupled receptor G2-like Neighboring gene adhesion G-protein coupled receptor G5 Neighboring gene 7-dehydrocholesterol reductase Neighboring gene MTSS I-BAR domain containing 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Involvement of the nuclear progestin receptor in LH-induced expression of membrane type 2-matrix metalloproteinase required for follicle rupture during ovulation in the medaka, Oryzias latipes. Ogiwara K, et al. Mol Cell Endocrinol, 2017 Jul 15. PMID 28416325
  2. Gelatinase A and membrane-type matrix metalloproteinases 1 and 2 are responsible for follicle rupture during ovulation in the medaka. Ogiwara K, et al. Proc Natl Acad Sci U S A, 2005 Jun 14. PMID 15941829, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A differential timing of expression of Pgr and Cebpb in the preovulatory follicles appears to explain the considerably long time-lag from the pgr gene activation to mmp15 gene expression.
    Title: Involvement of the nuclear progestin receptor in LH-induced expression of membrane type 2-matrix metalloproteinase required for follicle rupture during ovulation in the medaka, Oryzias latipes.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-15
Names
matrix metallopeptidase 15
membrane-type matrix metalloproteinase
NP_001098353.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104883.2 → NP_001098353.1  matrix metalloproteinase-15 precursor

    See identical proteins and their annotated locations for NP_001098353.1

    Status: PROVISIONAL

    Source sequence(s)
    AB072928
    UniProtKB/TrEMBL
    H2MKS4, Q76LU8
    Related
    ENSORLP00000019295.1, ENSORLT00000019296.2
    Conserved Domains (5) summary
    cd00094
    Location:332 → 525
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:122 → 288
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:122 → 288
    Peptidase_M10; Matrixin
    pfam01471
    Location:38 → 92
    PG_binding_1; Putative peptidoglycan binding domain
    pfam11857
    Location:586 → 658
    DUF3377; Domain of unknown function (DUF3377)

RefSeqs of Annotated Genomes: Oryzias latipes Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM223467v1 Primary Assembly

Genomic

  1. NC_019861.2 Reference ASM223467v1 Primary Assembly

    Range
    34703105..34733891
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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