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NCAN neurocan [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100082832, updated on 30-Apr-2024

Summary

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Gene symbol
NCAN
Gene description
neurocan
See related
Ensembl:ENSOANG00000032130
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X1
Exon count:
18
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) X1 NC_041749.1 (114773882..114869105)

Chromosome X1 - NC_041749.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 221 Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X associated ankyrin containing protein Neighboring gene nuclear receptor 2C2 associated protein Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene transmembrane 6 superfamily member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041749.1 Chromosome X1 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurocan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041749.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    114773882..114869105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029051710.2 → XP_028907543.1  neurocan core protein isoform X2

    UniProtKB/TrEMBL
    A0A6I8NQE6, A0A6I8NUZ8
    Related
    ENSOANP00000042813.1
    Conserved Domains (9) summary
    cd00033
    Location:1572 → 1628
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA03247
    Location:675 → 1252
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:408 → 899
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00054
    Location:1403 → 1439
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:160 → 254
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:261 → 356
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1369 → 1399
    EGF; EGF-like domain
    cl02432
    Location:1445 → 1568
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:47 → 161
    Ig; Immunoglobulin domain

  2. XM_029051708.1 → XP_028907541.1  neurocan core protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8NUZ8, K7EA70
    Conserved Domains (8) summary
    cd00033
    Location:1573 → 1629
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA03247
    Location:676 → 1253
    PHA03247; large tegument protein UL36; Provisional
    cd00054
    Location:1404 → 1440
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:161 → 255
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:262 → 357
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1370 → 1400
    EGF; EGF-like domain
    cl02432
    Location:1446 → 1569
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:48 → 162
    Ig; Immunoglobulin domain

  3. XM_029051712.2 → XP_028907545.1  neurocan core protein isoform X3

    UniProtKB/TrEMBL
    A0A6I8NUZ8
    Related
    ENSOANP00000044932.1
    Conserved Domains (8) summary
    cd00033
    Location:1571 → 1627
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA03247
    Location:674 → 1251
    PHA03247; large tegument protein UL36; Provisional
    cd00054
    Location:1402 → 1438
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:159 → 253
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:260 → 355
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1368 → 1398
    EGF; EGF-like domain
    cl02432
    Location:1444 → 1567
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:46 → 160
    Ig; Immunoglobulin domain

  4. XM_029051709.1 → XP_028907542.1  neurocan core protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8NUZ8, K7EA70
    Related
    ENSOANP00000030427.2, ENSOANT00000039665.2
    Conserved Domains (8) summary
    cd00033
    Location:1573 → 1629
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA03247
    Location:676 → 1253
    PHA03247; large tegument protein UL36; Provisional
    cd00054
    Location:1404 → 1440
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:161 → 255
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:262 → 357
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1370 → 1400
    EGF; EGF-like domain
    cl02432
    Location:1446 → 1569
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:48 → 162
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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