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ACVR1 activin A receptor type 1 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100077006, updated on 30-Apr-2024

Summary

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Gene symbol
ACVR1
Gene description
activin A receptor type 1
See related
Ensembl:ENSOANG00000006134
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See ACVR1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 9 NC_041736.1 (9190238..9286277, complement)

Chromosome 9 - NC_041736.1Genomic Context describing neighboring genes Neighboring gene cytohesin 1 interacting protein Neighboring gene uncharacterized LOC103171013 Neighboring gene activin A receptor type 1C Neighboring gene small nucleolar RNA SNORA7 Neighboring gene small nucleolar RNA U3 Neighboring gene coiled-coil domain containing 148

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041736.1 Chromosome 9 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transforming growth factor beta receptor activity, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dorsal/ventral pattern formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transforming growth factor beta receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of BMP receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
activin receptor type-1
Names
activin A receptor, type I

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041736.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    9190238..9286277 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007671136.4 → XP_007669326.1  activin receptor type-1 isoform X1

    See identical proteins and their annotated locations for XP_007669326.1

    UniProtKB/TrEMBL
    A0A6I8PDF6, F6VZX5
    Related
    ENSOANP00000052674.1
    Conserved Domains (3) summary
    cd14142
    Location:214 → 511
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam01064
    Location:33 → 103
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:191 → 218
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  2. XM_029072129.2 → XP_028927962.1  activin receptor type-1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PDF6, F6VZX5
    Conserved Domains (3) summary
    cd14142
    Location:214 → 511
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam01064
    Location:33 → 103
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:191 → 218
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  3. XM_001509575.5 → XP_001509625.1  activin receptor type-1 isoform X2

    UniProtKB/TrEMBL
    F6VZX5
    Conserved Domains (4) summary
    smart00220
    Location:212 → 496
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14142
    Location:205 → 502
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam01064
    Location:33 → 107
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:182 → 209
    TGF_beta_GS; Transforming growth factor beta type I GS-motif

  4. XM_007671137.4 → XP_007669327.1  activin receptor type-1 isoform X1

    See identical proteins and their annotated locations for XP_007669327.1

    UniProtKB/TrEMBL
    A0A6I8PDF6, F6VZX5
    Related
    ENSOANP00000009796.3
    Conserved Domains (3) summary
    cd14142
    Location:214 → 511
    STKc_ACVR1_ALK1; Catalytic domain of the Serine/Threonine Kinases, Activin Type I Receptor and Activin receptor-Like Kinase 1
    pfam01064
    Location:33 → 103
    Activin_recp; Activin types I and II receptor domain
    pfam08515
    Location:191 → 218
    TGF_beta_GS; Transforming growth factor beta type I GS-motif
Nucleotide Protein
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