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STAC2 SH3 and cysteine rich domain 2 [ Equus caballus (horse) ]

Gene ID: 100068363, updated on 17-Aug-2024

Summary

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Official Symbol
STAC2provided by VGNC
Official Full Name
SH3 and cysteine rich domain 2provided by VGNC
Primary source
VGNC:VGNC:23647
See related
Ensembl:ENSECAG00000000637
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 11 NC_009154.3 (23123815..23136641)

Chromosome 11 - NC_009154.3Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 20 Neighboring gene transcription factor CP2-like protein 1 Neighboring gene uncharacterized LOC102150940 Neighboring gene ribosomal protein L19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009154.3 Chromosome 11 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in skeletal muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH3 and cysteine-rich domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009154.3 Reference EquCab3.0 Primary Assembly

    Range
    23123815..23136641
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023652615.1 → XP_023508383.1  SH3 and cysteine-rich domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A9L0RSP5
    Conserved Domains (4) summary
    cd11985
    Location:293 → 345
    SH3_Stac2_C; C-terminal Src homology 3 domain of SH3 and cysteine-rich domain-containing protein 2 (Stac2)
    cd00029
    Location:111 → 161
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam16664
    Location:176 → 292
    STAC2_u1; Unstructured on SH3 and cysteine-rich domain-containing protein 2
    cl17036
    Location:352 → 402
    SH3; Src Homology 3 domain superfamily

  2. XM_023652616.1 → XP_023508384.1  SH3 and cysteine-rich domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A9L0RSP5
    Related
    ENSECAP00000066870.1, ENSECAT00000119823.1
    Conserved Domains (4) summary
    cd11985
    Location:274 → 326
    SH3_Stac2_C; C-terminal Src homology 3 domain of SH3 and cysteine-rich domain-containing protein 2 (Stac2)
    cd00029
    Location:92 → 142
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam16664
    Location:157 → 273
    STAC2_u1; Unstructured on SH3 and cysteine-rich domain-containing protein 2
    cl17036
    Location:333 → 383
    SH3; Src Homology 3 domain superfamily

RNA

  1. XR_002811476.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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