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LRRC8A leucine rich repeat containing 8 VRAC subunit A [ Equus caballus (horse) ]

Gene ID: 100066843, updated on 8-Mar-2024

Summary

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Official Symbol
LRRC8Aprovided by VGNC
Official Full Name
leucine rich repeat containing 8 VRAC subunit Aprovided by VGNC
Primary source
VGNC:VGNC:19792
See related
Ensembl:ENSECAG00000013359
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
6
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 25 NC_009168.3 (32591168..32619327)
102 previous assembly EquCab2.0 (GCF_000002305.2) 25 NC_009168.2 (32006752..32034924)

Chromosome 25 - NC_009168.3Genomic Context describing neighboring genes Neighboring gene endonuclease G Neighboring gene SPOUT domain containing methyltransferase 1 Neighboring gene kynurenine aminotransferase 1 Neighboring gene phytanoyl-CoA dioxygenase domain-containing protein 1-like Neighboring gene translation initiation factor IF-2-like Neighboring gene nucleoporin 188 Neighboring gene phytanoyl-CoA dioxygenase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
volume-regulated anion channel subunit LRRC8A
Names
leucine rich repeat containing 8 family member A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009168.3 Reference EquCab3.0 Primary Assembly

    Range
    32591168..32619327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001500261.6 → XP_001500311.1  volume-regulated anion channel subunit LRRC8A

    See identical proteins and their annotated locations for XP_001500311.1

    UniProtKB/TrEMBL
    F7BJ71
    Conserved Domains (4) summary
    COG4886
    Location:568 → 780
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:546 → 568
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:379 → 713
    internalin_A; class 1 internalin InlA
    pfam12534
    Location:1 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8

  2. XM_005605853.3 → XP_005605910.1  volume-regulated anion channel subunit LRRC8A

    See identical proteins and their annotated locations for XP_005605910.1

    UniProtKB/TrEMBL
    F7BJ71
    Related
    ENSECAP00000011134.1, ENSECAT00000013977.4
    Conserved Domains (4) summary
    COG4886
    Location:568 → 780
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:546 → 568
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:379 → 713
    internalin_A; class 1 internalin InlA
    pfam12534
    Location:1 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8

  3. XM_023629074.1 → XP_023484842.1  volume-regulated anion channel subunit LRRC8A

    UniProtKB/TrEMBL
    F7BJ71
    Conserved Domains (4) summary
    COG4886
    Location:568 → 780
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:546 → 568
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:379 → 713
    internalin_A; class 1 internalin InlA
    pfam12534
    Location:1 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8

  4. XM_023629073.1 → XP_023484841.1  volume-regulated anion channel subunit LRRC8A

    UniProtKB/TrEMBL
    F7BJ71
    Conserved Domains (4) summary
    COG4886
    Location:568 → 780
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:546 → 568
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:379 → 713
    internalin_A; class 1 internalin InlA
    pfam12534
    Location:1 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8

  5. XM_023629075.1 → XP_023484843.1  volume-regulated anion channel subunit LRRC8A

    UniProtKB/TrEMBL
    F7BJ71
    Conserved Domains (4) summary
    COG4886
    Location:568 → 780
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:546 → 568
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:379 → 713
    internalin_A; class 1 internalin InlA
    pfam12534
    Location:1 → 340
    Pannexin_like; Pannexin-like TM region of LRRC8
Nucleotide Protein
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