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SOCS5 suppressor of cytokine signaling 5 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100032188, updated on 8-May-2024

Summary

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Gene symbol
SOCS5
Gene description
suppressor of cytokine signaling 5
See related
EnsemblRapid:ENSMODG00000023104
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See SOCS5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 1 NC_077227.1 (660627286..660696249, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 1 NC_008801.1 (651020316..651089258, complement)

Chromosome 1 - NC_077227.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103105324 Neighboring gene uncharacterized LOC103105535 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene ras homolog family member Q

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077227.1 Reference mMonDom1.pri

    Range
    660627286..660696249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007476864.3 → XP_007476926.1  suppressor of cytokine signaling 5

    See identical proteins and their annotated locations for XP_007476926.1

    UniProtKB/TrEMBL
    F7AZP2
    Related
    ENSMODP00000066767.1, ENSMODT00000122221.1
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain

  2. XM_007476863.3 → XP_007476925.1  suppressor of cytokine signaling 5

    See identical proteins and their annotated locations for XP_007476925.1

    UniProtKB/TrEMBL
    F7AZP2
    Related
    ENSMODP00000065804.1, ENSMODT00000147438.1
    Conserved Domains (3) summary
    cd03739
    Location:482 → 537
    SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
    pfam12610
    Location:147 → 194
    SOCS; Suppressor of cytokine signalling
    cl15255
    Location:373 → 473
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein
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