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KMT2A lysine methyltransferase 2A [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100031440, updated on 6-Jun-2024

Summary

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Gene symbol
KMT2A
Gene description
lysine methyltransferase 2A
See related
EnsemblRapid:ENSMODG00000013474
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Also known as
MLL
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
37
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 4 NC_077230.1 (231916906..232000191, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 4 NC_008804.1 (231524705..231608060, complement)

Chromosome 4 - NC_077230.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 25 Neighboring gene tetratricopeptide repeat domain 36 Neighboring gene uncharacterized LOC103092640 Neighboring gene ATP synthase membrane subunit g Neighboring gene ubiquitination factor E4A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K4 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone methyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase 2A
Names
lysine (K)-specific methyltransferase 2A
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077230.1 Reference mMonDom1.pri

    Range
    231916906..232000191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056794302.1 → XP_056650280.1  histone-lysine N-methyltransferase 2A isoform X4

    UniProtKB/TrEMBL
    F7FMK4

  2. XM_056794301.1 → XP_056650279.1  histone-lysine N-methyltransferase 2A isoform X3

    UniProtKB/TrEMBL
    F7FMK4
    Related
    ENSMODP00000016853.6, ENSMODT00000017166.6

  3. XM_056794300.1 → XP_056650278.1  histone-lysine N-methyltransferase 2A isoform X2

    UniProtKB/TrEMBL
    F7FMK4
    Related
    ENSMODP00000088253.1, ENSMODT00000111759.1

  4. XM_056794299.1 → XP_056650277.1  histone-lysine N-methyltransferase 2A isoform X1

    UniProtKB/TrEMBL
    F7FMK4
Nucleotide Protein
Heading Accession and Version

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