U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

DNMT3A DNA methyltransferase 3 alpha [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100030681, updated on 8-May-2024

Summary

Go to the top of the page Help
Gene symbol
DNMT3A
Gene description
DNA methyltransferase 3 alpha
See related
EnsemblRapid:ENSMODG00000015850
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See DNMT3A in Genome Data Viewer
Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 1 NC_077227.1 (513804508..513971086, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 1 NC_008801.1 (505710009..505866053, complement)

Chromosome 1 - NC_077227.1Genomic Context describing neighboring genes Neighboring gene EFR3 homolog B Neighboring gene proopiomelanocortin Neighboring gene dystrobrevin beta Neighboring gene ASXL transcriptional regulator 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA (cytosine-5-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
DNA (cytosine-5)-methyltransferase 3A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077227.1 Reference mMonDom1.pri

    Range
    513804508..513971086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007475932.3 → XP_007475994.1  DNA (cytosine-5)-methyltransferase 3A isoform X2

    Conserved Domains (3) summary
    cd05835
    Location:289 → 375
    Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    COG0270
    Location:633 → 796
    Dcm; Site-specific DNA-cytosine methylase [Replication, recombination and repair]
    cd11729
    Location:488 → 615
    ADDz_Dnmt3a; ADDz domain found in DNA (cytosine-5) methyltransferases (C5-MTases) 3a (Dnmt3a)

  2. XM_016423800.2 → XP_016279286.1  DNA (cytosine-5)-methyltransferase 3A isoform X1

    Related
    ENSMODP00000019777.4, ENSMODT00000020131.4

  3. XM_056813135.1 → XP_056669113.1  DNA (cytosine-5)-methyltransferase 3A isoform X4

  4. XM_016423812.2 → XP_016279298.1  DNA (cytosine-5)-methyltransferase 3A isoform X3

    Related
    ENSMODP00000072305.1, ENSMODT00000150525.1

  5. XM_056813136.1 → XP_056669114.1  DNA (cytosine-5)-methyltransferase 3A isoform X5

    UniProtKB/TrEMBL
    F7F0E6
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.