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SPPL2B signal peptide peptidase like 2B [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100019923, updated on 8-May-2024

Summary

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Gene symbol
SPPL2B
Gene description
signal peptide peptidase like 2B
See related
EnsemblRapid:ENSMODG00000004756
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See SPPL2B in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 3 NC_077229.1 (77331118..77375665)
103 previous assembly MonDom5 (GCF_000002295.2) 3 NC_008803.1 (455213072..455257848)

Chromosome 3 - NC_077229.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and Ig domain containing 3 Neighboring gene LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene transmembrane serine protease 9 Neighboring gene uncharacterized LOC103097632 Neighboring gene translocase of inner mitochondrial membrane 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077229.1 Reference mMonDom1.pri

    Range
    77331118..77375665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007489329.3 → XP_007489391.1  signal peptide peptidase-like 2B isoform X4

    Conserved Domains (2) summary
    cd02129
    Location:38 → 157
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:210 → 499
    Peptidase_A22B; Signal peptide peptidase

  2. XM_007489327.3 → XP_007489389.1  signal peptide peptidase-like 2B isoform X1

    Related
    ENSMODP00000005860.4, ENSMODT00000005983.5
    Conserved Domains (2) summary
    cd02129
    Location:38 → 157
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:210 → 499
    Peptidase_A22B; Signal peptide peptidase

  3. XM_007489328.3 → XP_007489390.1  signal peptide peptidase-like 2B isoform X2

    UniProtKB/TrEMBL
    F6X1D2
    Conserved Domains (2) summary
    cd02129
    Location:38 → 157
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:210 → 499
    Peptidase_A22B; Signal peptide peptidase

  4. XM_056822217.1 → XP_056678195.1  signal peptide peptidase-like 2B isoform X3

  5. XM_056822216.1 → XP_056678194.1  signal peptide peptidase-like 2B isoform X3

RNA

  1. XR_008917367.1 RNA Sequence

  2. XR_465811.3 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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