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PDE2A phosphodiesterase 2A [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100014975, updated on 8-May-2024

Summary

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Gene symbol
PDE2A
Gene description
phosphodiesterase 2A
See related
EnsemblRapid:ENSMODG00000007870
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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See PDE2A in Genome Data Viewer
Location:
chromosome: 4
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 4 NC_077230.1 (348313582..348500618)
103 previous assembly MonDom5 (GCF_000002295.2) 4 NC_008804.1 (347176176..347363600)

Chromosome 4 - NC_077230.1Genomic Context describing neighboring genes Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 Neighboring gene uncharacterized LOC103096249 Neighboring gene uncharacterized LOC103096782 Neighboring gene uncharacterized LOC130453843 Neighboring gene microRNA mir-139 Neighboring gene myelin-oligodendrocyte glycoprotein-like Neighboring gene 26S proteasome regulatory subunit 8-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cGMP-stimulated cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cAMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cGMP-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-dependent 3',5'-cyclic phosphodiesterase
Names
phosphodiesterase 2A, cGMP-stimulated

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077230.1 Reference mMonDom1.pri

    Range
    348313582..348500618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001369136.4 → XP_001369173.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A5F8G2E8, F7EBA5
    Related
    ENSMODP00000009787.3, ENSMODT00000009979.5
    Conserved Domains (2) summary
    smart00065
    Location:421 → 570
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:667 → 900
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_056795024.1 → XP_056651002.1  cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X2

    Related
    ENSMODP00000041621.2, ENSMODT00000065186.2
Nucleotide Protein
Heading Accession and Version

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