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PKP2 plakophilin 2 [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100012832, updated on 8-May-2024

Summary

Gene symbol
PKP2
Gene description
plakophilin 2
See related
EnsemblRapid:ENSMODG00000012782
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
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Genomic context

See PKP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 5 NC_077231.1 (2013643..2115475, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 8 NC_008808.1 (8959559..9056760, complement)

Chromosome 5 - NC_077231.1Genomic Context describing neighboring genes Neighboring gene dynamin 1 like Neighboring gene tyrosine--tRNA ligase, mitochondrial Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene contactin 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-catenin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables intermediate filament binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-cell junction assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in desmosome organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intermediate filament bundle assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in intercalated disc IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077231.1 Reference mMonDom1.pri

    Range
    2013643..2115475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056797380.1XP_056653358.1  plakophilin-2 isoform X2

  2. XM_001363606.4XP_001363643.1  plakophilin-2 isoform X1

    UniProtKB/TrEMBL
    A0A5F8HBV7, F6S0Z1
    Related
    ENSMODP00000015991.4, ENSMODT00000016286.5
    Conserved Domains (2) summary
    cd00020
    Location:350467
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    sd00043
    Location:388424
    ARM; armadillo repeat [structural motif]
  3. XM_056797378.1XP_056653356.1  plakophilin-2 isoform X2