IHH Indian hedgehog signaling molecule [Oryctolagus cuniculus (rabbit)] - Gene

Summary

Gene symbol: IHH
Gene description: Indian hedgehog signaling molecule
See related: Ensembl:ENSOCUG00000028137
Gene type: protein coding
RefSeq status: MODEL
Organism: Oryctolagus cuniculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2023_02	current	UM_NZW_1.0 (GCF_009806435.1)	7	NC_067380.1 (13357924..13364654)

Chromosome 7 - NC_067380.1 Genomic Context describing neighboring genes

Genomic Sequence:: NC_067380.1 Chromosome 7 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

The causal locus for heritable craniosynostosis in this rabbit model is not located within the protein coding regions of Gli3, Ihh, Rab23, or Jag1.
Title: Molecular Analysis of Gli3, Ihh, Rab23, and Jag1 in a Rabbit Model of Craniosynostosis: Likely Exclusion as the Loci of Origin.
This study provides further evidence of chondrogenic induction of bone marrow-derived mesenchymal stem cells in vitro via IHH and SHH gene delivery.
Title: Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system.
Palmatin effect on osteoarthritis is likely mediated via the Wnt/beta-catenin and Hedgehog signaling
Title: Chondroprotective effects of palmatine on osteoarthritis in vivo and in vitro: A possible mechanism of inhibiting the Wnt/β-catenin and Hedgehog signaling pathways.

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Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables patched binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell fate specification	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell signaling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intein-mediated protein splicing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autoprocessing	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of gene expression	IEA Inferred from Electronic Annotation more info	PubMed
involved_in smoothened signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain