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Links from GEO DataSets

Items: 17

1.
Full record GDS2452

Histone deacetylase inhibitor effect on endothelial cells

Analysis of umbilical vein endothelial cells treated with 500 nM trichostatin A (TSA) for 24 hours. TSA is a histone deacetylase inhibitor. TSA treatment results in decreased endothelial nitric oxide synthase expression.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL201
Series:
GSE5856
6 Samples
Download data: CEL
DataSet
Accession:
GDS2452
ID:
2452
2.
Full record GDS3434

Macaca mulatta model of Helicobacter pylori infection: time course

Analysis of gastric mucosa from H. pylori specific pathogen free (SPF) rhesus monkeys infected with wildtype H. pylori strain J166 or its isogenic cag pathogenicity island (cag PAI) knockout mutant. Results provide insight into the role of cag PAI in the H. pylori host-pathogen interaction.
Organism:
Macaca mulatta; Homo sapiens
Type:
Expression profiling by array, count, 4 infection, 3 time sets
Platform:
GPL201
Series:
GSE8749
32 Samples
Download data: CEL, CHP
3.
Full record GDS3101

Non-small cell lung carcinoma cell line response to cisplatin

Analysis of cisplatin-resistant A549 lung adenocarcinoma cell line treated with cisplatin, a chemotherapy drug. Its cytotoxic effects are likely due to the DNA damage it induces in cells. Results provide insight into molecular mechanisms underlying the response of A549 to cisplatin insult.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL201
Series:
GSE6410
6 Samples
Download data: CEL
DataSet
Accession:
GDS3101
ID:
3101
4.
Full record GDS2780

Heavy metals effect on liver cell line

Analysis of liver carcinoma HepG2 cells exposed to various heavy metals. Results provide insight into the molecular basis of heavy metal cytotoxicity.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 10 agent, 3 other sets
Platform:
GPL201
Series:
GSE6907
30 Samples
Download data: CEL
DataSet
Accession:
GDS2780
ID:
2780
5.
Full record GDS2356

Hair follicles from males and females

Analysis of unstaged hair follicles from males and females. Results provide insight into the feasibility of extracting intact RNA, from a small number of hair follicles, in sufficient quantities for expression profiling.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 gender sets
Platform:
GPL201
Series:
GSE3058
10 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2356
ID:
2356
6.
Full record GDS2342

Chronic phase chronic myelogenous leukemia: CD34+ hematopoietic stem and progenitor cells

Analysis of CD34+ hematopoietic stem and progenitor cells from the bone marrow of untreated patients with chronic myelogenous leukemia (CML) in first chronic phase. Results provide insight into the pathogenesis of chronic phase CML.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL201
Series:
GSE5550
17 Samples
Download data
7.
Full record GDS2321

Polyethylene glycol-conjugated G-CSF mobilized CD34+ cells

Analysis of granulocyte colony stimulating factor (G-CSF) or polyethylene glycol-conjugated (pegylated) G-CSF mobilized CD34+ hematopoietic stem and progenitor cells from multiple myeloma patients undergoing chemotherapy. Pegylated G-CSF has a longer half-life than unconjugated G-CSF.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL201
Series:
GSE4688
16 Samples
Download data
DataSet
Accession:
GDS2321
ID:
2321
8.
Full record GDS2106

Lymphoblastoid cell lines from various CEPH pedigrees

Analysis of lymphoblastoid cell lines of 57 unrelated CEPH individuals from the International HapMap Project. Results used to find association between the expression phenotypes and SNP markers across the genome genotyped on the 57 individuals that belong to various CEPH pedigrees.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 20 genotype/variation sets
Platform:
GPL201
Series:
GSE2552
100 Samples
Download data: CEL
9.
Full record GDS2035

Vectorless gravity effect on T cell activation

Analysis of T cells costimulated with concanavalin A and anti-CD28 antibody in a vectorless gravity environment, which approximates true freefall or microgravity experienced in spaceflight. Results provide insight into the molecular basis of the altered immune function experienced by astronauts.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 individual, 2 protocol, 2 stress sets
Platform:
GPL201
Series:
GSE1709
12 Samples
Download data: CEL, EXP, RPT
DataSet
Accession:
GDS2035
ID:
2035
10.
Full record GDS1912

X-linked recessive dystonia-parkinsonism

Expression profiling of the caudate nucleus and nucleus accumbens from the brain of a patient with X-linked recessive dystonia-parkinsonism (XDP). XDP is an adult onset disorder characterized by dystonia and parkinsonism. Result provide insight into the pathogenesis of XDP.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 2 tissue sets
Platform:
GPL201
Series:
GSE3064
4 Samples
Download data: CEL
DataSet
Accession:
GDS1912
ID:
1912
11.
Full record GDS1852

siRNA knockdown and transcriptional response to DNA damage

Analysis of HEK293 cells following siRNA knockdown of p53, RelA, or ATM, and subsequent treatment with neocarzinostatin, a radiomimetic drug that induces DNA double-strand breaks. Results indicate RNAi combined with expression profiling is a powerful method for dissecting transcriptional networks.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 5 protocol sets
Platform:
GPL201
Series:
GSE1676
30 Samples
Download data: CEL
12.
Full record GDS1449

HIV-1 infection effect on peripheral blood mononuclear cells

Analysis of peripheral blood mononuclear cells from HIV-1 seropositive and seronegative individuals. Results used to identify a 10-gene signature used for determining HIV-1 serostatus, and a 6-gene signature to identify seropositive individuals exhibiting changes in CD4+ T cell counts.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 4 other, 3 protocol sets
Platform:
GPL201
Series:
GSE2171
87 Samples
Download data: CEL
DataSet
Accession:
GDS1449
ID:
1449
13.
Full record GDS1310

Neonatal mononuclear cell response to lipopolysaccharide

Analysis of neonatal mononuclear cells from cord blood incubated with 5 ug/ml lipopolysaccharide (LPS). Effect of LPS on adult mononuclear cells from peripheral blood compared. Results provide insight into the molecular basis for increased susceptibility of neonates to sepsis.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 cell type sets
Platform:
GPL201
Series:
GSE3140
12 Samples
Download data
DataSet
Accession:
GDS1310
ID:
1310
14.
Full record GDS1094

Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen

Expression profiling of U2OS osteosarcoma cell line expressing estrogen receptor/alpha heterodimer after treatment with 10 nM 17beta-estradiol (E2) or 10 nM 4-OH tamoxifen (4HT) for 24 hours. Results provide insight into the role of estrogen receptor/alpha heterodimer in gene regulation.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent, 3 genotype/variation sets
Platform:
GPL201
Series:
GSE2292
45 Samples
Download data: CEL
DataSet
Accession:
GDS1094
ID:
1094
15.
Full record GDS1028

Severe acute respiratory syndrome expression profile

Expression profiling of peripheral blood mononuclear cells (PBMC) from 10 adult patients with severe acute respiratory syndrome (SARS). Results provide insight into the host immune response to the SARS coronavirus.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL201
Series:
GSE1739
14 Samples
Download data
16.
Full record GDS852

Alveolar epithelial cell line A549 response to acute lung injury causing stimuli: time course

Examination of alveolar epithelial A549 cells in models of pulmonary parenchymal cell activation: exposure to tumor necrosis factor-alpha (TNF-alpha), lipopolysaccharide (LPS), or cyclic stretch. Cells examined 1 and 4 hours after exposure to each acute lung injury-causing stimulus.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 5 protocol, 2 time sets
Platform:
GPL201
Series:
GSE1541
20 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS852
ID:
852
17.
Full record GDS838

Imatinib effects on chronic myelogenous leukemia CD34+ cells

Comparison of purified bone marrow CD34+ cells from imatinib-treated chronic myelogenous leukemia (CML) patients and healthy donors.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent sets
Platform:
GPL201
Series:
GSE1418
14 Samples
Download data: CEL
DataSet
Accession:
GDS838
ID:
838
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