Table 16Interventions, numbers of patients, and quality ratings of controlled trials in adults with panic disorder

Author, YearInterventionsNResultsQuality rating
SSRIs compared with Placebo
Asnis et al., 2001197Fluvoxamine compared with Placebo188Significantly greater efficacy of fluvoxamineFair
Black et al., 1993198Fluvoxamine compared with Placebo75Significantly greater efficacy of fluvoxamineFair
Hoehn-Saric et al., 1993196Fluvoxamine compared with Placebo50Significantly greater efficacy of fluvoxamineFair
SSRIs compared with SSRIs
Bandelow et al., 2004192Paroxetine compared with Sertraline225No differenceFair
Pollack et al., 2007193Venlafaxine ER compared with Paroxetine664No differenceFair
Pollack et al., 2007194Venlafaxine ER compared with Paroxetine653Significantly greater efficacy of venlafaxine ER 225 mg/d compared to paroxetine 40 mg/dFair
Stahl et al., 2003190Citalopram compared with Escitalopram compared with Placebo366No differenceFair

Abbreviations: ER, Extended Release

From: Results

Cover of Drug Class Review: Second-Generation Antidepressants
Drug Class Review: Second-Generation Antidepressants: Final Update 5 Report [Internet].
Gartlehner G, Hansen RA, Reichenpfader U, et al.
Portland (OR): Oregon Health & Science University; 2011 Mar.
Copyright © 2011 Oregon Health & Science University.

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