Conserved Protein Domain Family
HemN_C
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pfam06969: HemN_C 
HemN C-terminal domain
Members of this family are all oxygen-independent coproporphyrinogen-III oxidases (HemN). This enzyme catalyzes the oxygen-independent conversion of coproporphyrinogen-III to protoporphyrinogen-IX, one of the last steps in haem biosynthesis. The function of this domain is unclear, but comparison to other proteins containing a radical SAM domain (pfam04055) suggest it may be a substrate binding domain.
Links
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Statistics
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PSSM-Id: 462055
Aligned: 42 rows
Threshold Bit Score: 45.3106
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDO44873      303 QSNAVILEEIIMLGLRTSEGIPNERFNHYITATssgslREIFEgCSDVRDFMAEGLLQLDERGLRATPSGLA 374
Q182E9        315 LSEKDMIEEKIFMGLRMNKGIKFEDFKKKFGID-----FREKY-NKQIEMLLARKLINQSFEGIQLTQKGRE 380 Clostridioides diffici...
jgi:Haur_1001 347 CEPQDRDFETIMMGLRLNCGLGFAHFQQRTGHD-----LLAQY-QPIIEQLVGQGLLEQTTNAIRFTPRGRM 412
Q8F348        311 ytkpNFYEELILSLFRLFQPILMESFYELIPDQ------SQTL-DLQLKKFQESGLCEFSNGIFQWKPEAVl 375 Leptospira interrogans
Q6MC79        311 LDPIAHLKELFVIQIRLCQGISIADFEQRHGK------LSQET-LETIEQFILDGFLTQSNQILSLTKKGVL 375 Candidatus Protochlamy...
EEC11362      326 LTHQEIIEEMLMMGLRLSKGINISTLEQKLNTK-----LENILdMNNLKHYQSQDLIKLD-KNIYLTDKGLm 391
WP_011711755  311 LTPQEAGNEALVMGLRMGEGMSKATYQWVRGVS-----LQQSV-GDGLAWFERQGMLAQSATHVWLTPRGLR 376 Magnetococcus marinus
Q7UKX5        310 ITLEQYARELAAFGVRQLDGIDLSTIDNRTSID-----LETLL-AKTLTKLQSMELVTHENHHLRLTCRGIL 375 Pirellula sp.
Q9I6A9        309 lEAADLPFEFMMNVLRLVDGVPAALYPQRTGQP-----LAAI--ADACAAARDAGLLADDPQHLRPSERGQL 373 Pseudomonas aeruginosa
P43899        306 vPKIDRPFEFFMNRFRLLEAVPKQEFEDYTGLS------QSAV-KNQIDFAIQQNYIVENADSWQITEHGkl 370 Haemophilus influenzae...
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