Conserved Protein Domain Family
Syntaxin-5_N
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pfam11416: Syntaxin-5_N (this model, PSSM-Id:288298 is obsolete and has been replaced by 463276)
Syntaxin-5 N-terminal, Sly1p-binding domain
Syntaxin-5_N is the Sed5 N-terminal and the N-terminus of Syntaxin-5-like proteins. It is the region of Syntaxin that interacts with Sly1p, a positive regulator of intracellular membrane fusion, allowing SM (cytosolic Sec1/munc18-like) proteins to stay associated with the assembling fusion machinery. This allows the SM proteins to participate in late fusion steps.
Links
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Statistics
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PSSM-Id: 288298
Aligned: 33 rows
Threshold Bit Score: 32.4018
Created: 22-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q28CE9        43 DIMSCRDRTAEFISACKSLQGR 64  western clawed frog
CDM81832       7 APASFRDRTNEFRSAVESARRH 28  bread wheat
XP_003467958  53 GIMSCRDRTQEFLSACRSLQSQ 74  domestic guinea pig
XP_002604461  34 AEMSCRDRTSEFISAVKSMQMR 55  Florida lancelet
XP_784377     54 GDMTCRDRTQEFLSTIKSMQSR 75  purple sea urchin
EFX88848      15 TNASSRDRTAEFLSAVRSFQNR 36  common water flea
ESW96345       4 YPPNVQDRTLEFLQCVSTFNKQ 25  Ogataea parapolymorpha DL-1
XP_003670251   5 QPRNIRDRTSEFQQSVLTCKKR 26  Naumovozyma dairenensis CBS 421
XP_011273337   8 QPQDIRNRTVEFQQCVNTFNKR 29  Wickerhamomyces ciferrii
CCF47929      10 YGQSVKDRTTEFHSLVDSISSR 31  Ustilago hordei
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