Conserved Protein Domain Family
Syntaxin-5_N
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pfam11416: Syntaxin-5_N 
Syntaxin-5 N-terminal, Sly1p-binding domain
Syntaxin-5_N is the Sed5 N-terminal and the N-terminus of Syntaxin-5-like proteins. It is the region of Syntaxin that interacts with Sly1p, a positive regulator of intracellular membrane fusion, allowing SM (cytosolic Sec1/munc18-like) proteins to stay associated with the assembling fusion machinery. This allows the SM proteins to participate in late fusion steps.
Links
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Statistics
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PSSM-Id: 463276
Aligned: 29 rows
Threshold Bit Score: 34.4726
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EME38693       7 TSHASIQDRTPEFRSILAQAQKS 29 
XP_012809038  42 ADIMSCRDRTAEFISACKSLQGR 64 
XP_021065309  52 PDTMSCRDRTQEFQSACKSLQSR 74 
XP_003467958  52 PGIMSCRDRTQEFLSACRSLQSQ 74 
EEN60472      33 SAEMSCRDRTSEFISAVKSMQMR 55 
EFX88848      14 STNASSRDRTAEFLSAVRSFQNR 36 
GAC73840       8 YYGHSVKDRTSEFHGLVESIASR 30 
CCF47929       9 YYGQSVKDRTTEFHSLVDSISSR 31 
CCD25008       4 LQPRNIRDRTSEFQQSVLTCKKR 26 
XP_011273337   7 NQPQDIRNRTVEFQQCVNTFNKR 29
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