GSM4007150: MV411.1000nM.GSK862.d4.n2 [S1-100]; Homo sapiens; RNA-Seq - SRA

SRX6657066: GSM4007150: MV411.1000nM.GSK862.d4.n2 [S1-100]; Homo sapiens; RNA-Seq
6 ILLUMINA (Illumina NovaSeq 6000) runs: 120.2M spots, 36.3G bases, 10.4Gb downloads

Submitted by: NCBI (GEO)

Study: RNA-seq of DNMT1 inhibitor treated AML cell lines

PRJNA558691 • SRP217480 • All experiments • All runs

show Abstracthide Abstract

Genome wide demethylation by DNMT1 inhibitors GSK3685032 results in up-regulation of epigenetically-silenced genes. Overall design: Differential expression was perfomed for each cell line following DNMT1 inhibitor or vehicle treatment across 6 point dose titration and 6 day timecourse. Differentially epressed gene lists were compared across the dose and timecourse.

Sample: MV411.1000nM.GSK862.d4.n2 [S1-100]

SAMN12496528 • SRS5217526 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: Illumina NovaSeq 6000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: RNA was extracted using Qiagen Rneasy Mini kit Libraries were prepared at the NYU Medical Center Genome Technology Center All 150 PE libraries were sequenced across 6 lanes for a total of 12 fastq samples per sample.

Experiment attributes:

GEO Accession: GSM4007150

Links:

NCBI link: NCBI Entrez (gds)

Runs: 6 runs, 120.2M spots, 36.3G bases, 10.4Gb

Run	# of Spots	# of Bases	Size	Published
SRR9905321	21,480,047	6.5G	1.8Gb	2021-06-30
SRR9905322	22,060,957	6.7G	1.9Gb	2021-06-30
SRR9905323	21,632,463	6.5G	1.9Gb	2021-06-30
SRR9905324	22,530,506	6.8G	1.9Gb	2021-06-30
SRR9905325	16,258,326	4.9G	1.4Gb	2021-06-30
SRR9905326	16,197,802	4.9G	1.4Gb	2021-06-30

ID:: 8779995

SRA

Sequence Read Archive

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