GSM3565464: TACATT: HCC1806_Abemaciclib_0.1; Homo sapiens; RNA-Seq - SRA

SRX5255666: GSM3565464: TACATT: HCC1806_Abemaciclib_0.1; Homo sapiens; RNA-Seq
1 ILLUMINA (NextSeq 550) run: 771,493 spots, 44.3M bases, 57.1Mb downloads

Submitted by: NCBI (GEO)

Study: Digital gene expression (DGE) based transcript profiling of CDK inhibitors

PRJNA515531 • SRP179781 • All experiments • All runs

show Abstracthide Abstract

We compare differences in gene expression induced after 6 hours of exposure to one of three CDK4/6 inhibitors or a pan-CDK inhibitor Overall design: mRNA levels for 7 breast cancer cell lines or PDX models treated with one of three CDK4/6 inhibitors (abemaciclib, palbociclib, or ribociclib) at 4 concentrations (0.1, 0.3, 1, 3 um) or the pan-CDK inhibitor alvocidib at 2 concentrations (0.1, 1 um) in triplicate.

Sample: TACATT: HCC1806_Abemaciclib_0.1

SAMN10760329 • SRS4257177 • All experiments • All runs

Organism: Homo sapiens

Library:

Instrument: NextSeq 550

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: SINGLE

Construction protocol: RNA was extracted using TCL lysis buffer, samples were using universal adapters, barcodes, unique molecular identifiers, and a template switching reverse transcriptase. Libraries were prepared using Nextera DNA kit (Illumina). Digitial gene expression (DGE)

Experiment attributes:

GEO Accession: GSM3565464

Links:

NCBI link: NCBI Entrez (gds)

Runs: 1 run, 771,493 spots, 44.3M bases, 57.1Mb

Run	# of Spots	# of Bases	Size	Published
SRR8448666	771,493	44.3M	57.1Mb	2019-06-27

ID:: 7091942

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