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SRX5184917: GSM3532965: 2_ATRA; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina HiSeq 2500) run: 17.6M spots, 896.1M bases, 525.1Mb downloads

Submitted by: NCBI (GEO)
Study: RNA-seq of HL-60 cells following treatment with different compounds
show Abstracthide Abstract
We investigate the effects of GCN5 and LSD1 inhibition in acute myeloid leukemia. Therefore, we characterized gene expression changes by RNA-seq in AML cells (AML M2 cell line HL-60) following treatment with ATRA, MB3, GSK-LSD1 and their combinations. Overall design: 21 samples in 7 groups: Untreated (3 samples), ATRA (3 samples), ATRA+MB3 (3 samples), ATRA+GSK-LSD1 (3 samples), ATRA+GSK-LSD1+MB3 (3 samples), MB3 (3 samples) and GSK-LSD1 (3 samples)
Sample: 2_ATRA
SAMN10655774 • SRS4191606 • All experiments • All runs
Organism: Homo sapiens
Library:
Instrument: Illumina HiSeq 2500
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: SINGLE
Construction protocol: Total RNA was isolated and purified using Direct-zol™ RNA Kit (Zymo Research) Library preparation was done using Illumina's TruSeq Stranded mRNA Library Preparation Kit following the manufacturer's instruction.
Experiment attributes:
GEO Accession: GSM3532965
Links:
Runs: 1 run, 17.6M spots, 896.1M bases, 525.1Mb
Run# of Spots# of BasesSizePublished
SRR837486117,570,180896.1M525.1Mb2019-11-28

ID:
7000012

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