GSM7091611: R986-9-9-IL21-138265; Homo sapiens; RNA-Seq - SRA

SRX19635481: GSM7091611: R986-9-9-IL21-138265; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina NovaSeq 6000) run: 17.5M spots, 3.5G bases, 1.1Gb downloads

External Id: GSM7091611_r1

Submitted by: The University of Texas MD Anderson Cancer Center

Study: IL-21 induces antitumor response in NK cells via CEBPD

PRJNA943227 • SRP426652 • All experiments • All runs

show Abstracthide Abstract

NK cells engineered to express IL-21 (IL-21 NK) acquire strong antitumor activity, with the ability to respond to glioblastoma (GBM) rechallenge in vitro and in vivo. IL-21 NK cells have a unique signature of chromatin accessibility, with CCAAT/Enhancer-Binding Protein (C/EBP), especially CEBPD, serving as key transcription factors regulating their memory response. Overall design: The objective of this study was to investigate the epigenetic factors that contributing for memory formation in NK cells

Sample: R986-9-9-IL21-138265

SAMN33715550 • SRS17004513 • All experiments • All runs

Organism: Homo sapiens

Library:

Name: GSM7091611

Instrument: Illumina NovaSeq 6000

Strategy: RNA-Seq

Source: TRANSCRIPTOMIC

Selection: cDNA

Layout: PAIRED

Construction protocol: Libraries were prepared using Illumina next generation RNA sequencing . By applying RNA and ATAC sequencing, we want to investigate the epigenetic factors that contributing for IL-21-induced memory formation in NK cells

Runs: 1 run, 17.5M spots, 3.5G bases, 1.1Gb

Run	# of Spots	# of Bases	Size	Published
SRR23804198	17,533,967	3.5G	1.1Gb	2024-07-09

ID:: 26933337

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