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SRX19447531: GSM7053939: Hnf4ctrl.Hnf4dTEC.Pdpn-CD104-.mTEClo.rep#1-7.FBC; Mus musculus; OTHER
2 ILLUMINA (Illumina NovaSeq 6000) runs: 55.9M spots, 7G bases, 2.5Gb downloads

External Id: GSM7053939_r1
Submitted by: CBDM, Microbiology and Immunobiology, Harvard Medical School
Study: Hnf4 controls gut and liver gene programs in the thymus [scRNAseq]
show Abstracthide Abstract
We profiled medullary thymic epithelial cells by scRNA-seq to investigate mechanisms of T-cell tolerance. Overall design: scRNA-seq of mTECs
Sample: Hnf4ctrl.Hnf4dTEC.Pdpn-CD104-.mTEClo.rep#1-7.FBC
SAMN33385896 • SRS16840766 • All experiments • All runs
Organism: Mus musculus
Library:
Name: GSM7053939
Instrument: Illumina NovaSeq 6000
Strategy: OTHER
Source: OTHER
Selection: other
Layout: PAIRED
Construction protocol: mTEC were prepared by digesting thymi with collagenase and dispase, magnetically depleting CD45+ cells, staining with fluorescent antibodies, hashing with TotalSeq antibodies against H2-Kb, and flow sorting mTECs into DMEM/10%FCS. Purified cells were sent to the Broad Institute Genomics Platform, which performed encapsulation and RNA and hash library preparation following 10X Genomics protocols (3' v3.1 chemistry) scRNA-seq
Runs: 2 runs, 55.9M spots, 7G bases, 2.5Gb
Run# of Spots# of BasesSizePublished
SRR2356039828,330,0833.6G1.3Gb2023-06-28
SRR2356039927,599,0343.5G1.2Gb2023-06-28

ID:
26721947

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