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SRX19301391: GSM7029810: BM progenitor cells, mRNA-derived cDNA [AsanoWTA1]; Mus musculus; RNA-Seq
1 ILLUMINA (Illumina NovaSeq 6000) run: 543.4M spots, 120G bases, 29.2Gb downloads

External Id: GSM7029810_r1
Submitted by: Immune Regulation, Life Sciences, Tokyo University of Pharmacy and Life Sciences
Study: GMP-MoPs can be classified as an independent cell type that differentiate from GMPs through proNeu1 without going through the MDP-cMoP pathway [scRNA-seq]
show Abstracthide Abstract
This analysis was performed to track the bifurcation of differentiation path of neutrophil lineage at the proNeu1 stage, giving rise to either prNeu2 or GMP-MoPs. Overall design: A single cell RNA-seq analysis of cKit+Lin- bone marrow progenitor cells and GMP-MoPs from one naïve mouse and one LPS-injected mouse, cMoPs from one naïve mouse.
Sample: BM progenitor cells, mRNA-derived cDNA [AsanoWTA1]
SAMN33184238 • SRS16701435 • All experiments • All runs
Organism: Mus musculus
Library:
Name: GSM7029810
Instrument: Illumina NovaSeq 6000
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC SINGLE CELL
Selection: cDNA
Layout: PAIRED
Construction protocol: BM cells from one naïve mouse and one LPS-injected mouse were sorted by FACSAriaIII and stained with different DNA barcode-conjugated PE-streptavidins (BioLegend Totalseq PE-streptavidin (A961, A962, A963, A964, and A965)) to identify each sample origin. Sorted cells were pooled and subject to scRNA-seq using BD RhapsodyTM Single-Cell Analysis System (BD Biosciences), and resulted cDNA was amplified by TAS-Seq protocol. 100 cells /A961 ; 100 cells /A962 ; 15,000 cells /A963 ; 100 cells /A964 ; 15,000 cells /A965 were loaded onto BD RhapsodyTM Single-Cell Analysis System. cDNA library was processed to sequencing library by using NEBNext UltraII FS library prep kit for Illumina (New England Biolabs). Sequencing adapters were added to associated Totalseq PE-streptavidin libraries by PCR. Pooled library concentration was adjusted to 2.0 nM and 12% PhiX control library v3 (Illumina) was spiked into the library.
Runs: 1 run, 543.4M spots, 120G bases, 29.2Gb
Run# of Spots# of BasesSizePublished
SRR23360136543,391,893120G29.2Gb2023-03-13

ID:
26545125

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