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SRX1009946: Transcriptome profiles using next generation sequencing reveal liver changes in the early stage of diabetes in tree shrew (Tupaia belangeri chinensis)
1 ILLUMINA (Illumina HiSeq 2000) run: 73.7M spots, 14.9G bases, 9.6Gb downloads

Submitted by: Kunming Institute of Zoology
Study: Tupaia chinensis Raw sequence reads
show Abstracthide Abstract
Diabetes is now one of the most common non-communicable diseases globally, and becoming the leading risk factor of cardiovascular disease and associated complications that result in potential morbidity and mortality. However, the liver changes in the early stage of diabetes is still unknown because the importance of liver function in the development and treatment of diabetes. In recent years, the next generation sequencing technologies has developed to be a powerful tool to explore the transcriptome characterization and gene expression profiling in a high-throughput manner, and it has been gradually used in the research of metabolism diseases. Additionally, tree shrew has been reported to be a potentially new animal model to study metabolic diseases. In this study, we characterized the liver transcriptome profiles of diabetic tree shrews to determine the differentially expressed genes, and to explore the role of hyperglycemia in liver changes.
Sample: liver tissues from Tupaia belangeri chinensis
SAMN03568805 • SRS922917 • All experiments • All runs
Library:
Instrument: Illumina HiSeq 2000
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: PAIRED
Spot descriptor:
forward111  reverse

Runs: 1 run, 73.7M spots, 14.9G bases, 9.6Gb
Run# of Spots# of BasesSizePublished
SRR199791673,656,61714.9G9.6Gb2016-04-26

ID:
1464700

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