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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs743777

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chr22:37155567 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
A>C / A>G
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.354603 (93860/264690, TOPMED)
G=0.313036 (66187/211436, ALFA)
G=0.362104 (50704/140026, GnomAD) (+ 20 more)
G=0.34837 (27414/78692, PAGE_STUDY)
G=0.07959 (1334/16760, 8.3KJPN)
G=0.2768 (1386/5008, 1000G)
G=0.2569 (1151/4480, Estonian)
G=0.3067 (1182/3854, ALSPAC)
G=0.3177 (1178/3708, TWINSUK)
G=0.0973 (285/2930, KOREAN)
G=0.3438 (645/1876, HapMap)
G=0.0917 (168/1832, Korea1K)
G=0.319 (318/998, GoNL)
G=0.085 (65/762, PRJEB37584)
G=0.158 (99/626, Chileans)
G=0.262 (157/600, NorthernSweden)
G=0.324 (70/216, Qatari)
G=0.134 (29/216, Vietnamese)
A=0.358 (73/204, SGDP_PRJ)
G=0.39 (24/62, Ancient Sardinia)
A=0.50 (20/40, GENOME_DK)
G=0.50 (20/40, GENOME_DK)
A=0.41 (9/22, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
IL2RB : Intron Variant
Publications
13 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr 22 NC_000022.11:g.37155567A>C
GRCh38.p13 chr 22 NC_000022.11:g.37155567A>G
GRCh37.p13 chr 22 NC_000022.10:g.37551607A>C
GRCh37.p13 chr 22 NC_000022.10:g.37551607A>G
Gene: IL2RB, interleukin 2 receptor subunit beta (minus strand)
Molecule type Change Amino acid[Codon] SO Term
IL2RB transcript variant 2 NM_001346222.1:c.-33-1136…

NM_001346222.1:c.-33-11362T>G

N/A Intron Variant
IL2RB transcript variant 3 NM_001346223.2:c.-33-1136…

NM_001346223.2:c.-33-11362T>G

N/A Intron Variant
IL2RB transcript variant 1 NM_000878.5:c. N/A Genic Upstream Transcript Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 211436 A=0.686964 G=0.313036
European Sub 172754 A=0.682751 G=0.317249
African Sub 9642 A=0.4994 G=0.5006
African Others Sub 330 A=0.409 G=0.591
African American Sub 9312 A=0.5026 G=0.4974
Asian Sub 6664 A=0.8866 G=0.1134
East Asian Sub 4774 A=0.8907 G=0.1093
Other Asian Sub 1890 A=0.8762 G=0.1238
Latin American 1 Sub 1014 A=0.5897 G=0.4103
Latin American 2 Sub 7392 A=0.8149 G=0.1851
South Asian Sub 356 A=0.851 G=0.149
Other Sub 13614 A=0.70905 G=0.29095


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 A=0.645397 G=0.354603
gnomAD - Genomes Global Study-wide 140026 A=0.637896 G=0.362104
gnomAD - Genomes European Sub 75872 A=0.68100 G=0.31900
gnomAD - Genomes African Sub 41906 A=0.50031 G=0.49969
gnomAD - Genomes American Sub 13652 A=0.74480 G=0.25520
gnomAD - Genomes Ashkenazi Jewish Sub 3320 A=0.7142 G=0.2858
gnomAD - Genomes East Asian Sub 3126 A=0.8640 G=0.1360
gnomAD - Genomes Other Sub 2150 A=0.6730 G=0.3270
The PAGE Study Global Study-wide 78692 A=0.65163 G=0.34837
The PAGE Study AfricanAmerican Sub 32512 A=0.50615 G=0.49385
The PAGE Study Mexican Sub 10810 A=0.81184 G=0.18816
The PAGE Study Asian Sub 8316 A=0.8980 G=0.1020
The PAGE Study PuertoRican Sub 7914 A=0.6803 G=0.3197
The PAGE Study NativeHawaiian Sub 4534 A=0.6813 G=0.3187
The PAGE Study Cuban Sub 4230 A=0.6648 G=0.3352
The PAGE Study Dominican Sub 3828 A=0.5875 G=0.4125
The PAGE Study CentralAmerican Sub 2450 A=0.7678 G=0.2322
The PAGE Study SouthAmerican Sub 1982 A=0.7836 G=0.2164
The PAGE Study NativeAmerican Sub 1260 A=0.7222 G=0.2778
The PAGE Study SouthAsian Sub 856 A=0.818 G=0.182
8.3KJPN JAPANESE Study-wide 16760 A=0.92041 G=0.07959
1000Genomes Global Study-wide 5008 A=0.7232 G=0.2768
1000Genomes African Sub 1322 A=0.4781 G=0.5219
1000Genomes East Asian Sub 1008 A=0.8879 G=0.1121
1000Genomes Europe Sub 1006 A=0.6958 G=0.3042
1000Genomes South Asian Sub 978 A=0.852 G=0.148
1000Genomes American Sub 694 A=0.810 G=0.190
Genetic variation in the Estonian population Estonian Study-wide 4480 A=0.7431 G=0.2569
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 A=0.6933 G=0.3067
UK 10K study - Twins TWIN COHORT Study-wide 3708 A=0.6823 G=0.3177
KOREAN population from KRGDB KOREAN Study-wide 2930 A=0.9027 C=0.0000, G=0.0973
HapMap Global Study-wide 1876 A=0.6562 G=0.3438
HapMap American Sub 768 A=0.754 G=0.246
HapMap African Sub 678 A=0.456 G=0.544
HapMap Asian Sub 254 A=0.913 G=0.087
HapMap Europe Sub 176 A=0.631 G=0.369
Korean Genome Project KOREAN Study-wide 1832 A=0.9083 G=0.0917
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 A=0.681 G=0.319
CNV burdens in cranial meningiomas Global Study-wide 762 A=0.915 G=0.085
CNV burdens in cranial meningiomas CRM Sub 762 A=0.915 G=0.085
Chileans Chilean Study-wide 626 A=0.842 G=0.158
Northern Sweden ACPOP Study-wide 600 A=0.738 G=0.262
Qatari Global Study-wide 216 A=0.676 G=0.324
A Vietnamese Genetic Variation Database Global Study-wide 216 A=0.866 G=0.134
SGDP_PRJ Global Study-wide 204 A=0.358 G=0.642
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 62 A=0.61 G=0.39
The Danish reference pan genome Danish Study-wide 40 A=0.50 G=0.50
Siberian Global Study-wide 22 A=0.41 G=0.59
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement A= C G
GRCh38.p13 chr 22 NC_000022.11:g.37155567= NC_000022.11:g.37155567A>C NC_000022.11:g.37155567A>G
GRCh37.p13 chr 22 NC_000022.10:g.37551607= NC_000022.10:g.37551607A>C NC_000022.10:g.37551607A>G
IL2RB transcript variant 2 NM_001346222.1:c.-33-11362= NM_001346222.1:c.-33-11362T>G NM_001346222.1:c.-33-11362T>C
IL2RB transcript variant 3 NM_001346223.2:c.-33-11362= NM_001346223.2:c.-33-11362T>G NM_001346223.2:c.-33-11362T>C
IL2RB transcript variant X1 XM_005261599.1:c.-34+708= XM_005261599.1:c.-34+708T>G XM_005261599.1:c.-34+708T>C
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

97 SubSNP, 22 Frequency submissions
No Submitter Submission ID Date (Build)
1 TSC-CSHL ss93027 Oct 05, 2000 (86)
2 SC_SNP ss8296255 Apr 21, 2003 (114)
3 BCM_SSAHASNP ss11007663 Jul 11, 2003 (116)
4 SC_SNP ss13359286 Dec 05, 2003 (119)
5 ABI ss44301339 Mar 13, 2006 (126)
6 AFFY ss66054054 Nov 29, 2006 (127)
7 PERLEGEN ss69272720 May 16, 2007 (127)
8 AFFY ss75963693 Dec 08, 2007 (130)
9 KRIBB_YJKIM ss81435786 Dec 16, 2007 (130)
10 HGSV ss81825708 Dec 15, 2007 (130)
11 1000GENOMES ss112647748 Jan 25, 2009 (130)
12 ILLUMINA-UK ss117405614 Feb 14, 2009 (130)
13 GMI ss157181586 Dec 01, 2009 (131)
14 ILLUMINA ss160879303 Dec 01, 2009 (131)
15 COMPLETE_GENOMICS ss169257765 Jul 04, 2010 (132)
16 BUSHMAN ss204089821 Jul 04, 2010 (132)
17 BCM-HGSC-SUB ss208835979 Jul 04, 2010 (132)
18 1000GENOMES ss228683260 Jul 14, 2010 (132)
19 1000GENOMES ss238071969 Jul 15, 2010 (132)
20 1000GENOMES ss244189248 Jul 15, 2010 (132)
21 ILLUMINA ss244309490 Jul 04, 2010 (132)
22 BL ss255904554 May 09, 2011 (134)
23 GMI ss283638159 May 04, 2012 (137)
24 PJP ss292762125 May 09, 2011 (134)
25 ILLUMINA ss482566925 Sep 08, 2015 (146)
26 EXOME_CHIP ss491571349 May 04, 2012 (137)
27 TISHKOFF ss566645600 Apr 25, 2013 (138)
28 SSMP ss662575345 Apr 25, 2013 (138)
29 ILLUMINA ss780686522 Aug 21, 2014 (142)
30 ILLUMINA ss783360047 Aug 21, 2014 (142)
31 EVA-GONL ss995359959 Aug 21, 2014 (142)
32 JMKIDD_LAB ss1082664500 Aug 21, 2014 (142)
33 1000GENOMES ss1367195224 Aug 21, 2014 (142)
34 DDI ss1429259064 Apr 01, 2015 (144)
35 EVA_GENOME_DK ss1579756125 Apr 01, 2015 (144)
36 EVA_UK10K_ALSPAC ss1640011239 Apr 01, 2015 (144)
37 EVA_UK10K_TWINSUK ss1683005272 Apr 01, 2015 (144)
38 EVA_DECODE ss1699430088 Apr 01, 2015 (144)
39 EVA_SVP ss1713741863 Apr 01, 2015 (144)
40 ILLUMINA ss1752421207 Sep 08, 2015 (146)
41 HAMMER_LAB ss1809792533 Sep 08, 2015 (146)
42 ILLUMINA ss1917955720 Feb 12, 2016 (147)
43 WEILL_CORNELL_DGM ss1938926498 Feb 12, 2016 (147)
44 ILLUMINA ss1946590884 Feb 12, 2016 (147)
45 ILLUMINA ss1959980186 Feb 12, 2016 (147)
46 GENOMED ss1969274318 Jul 19, 2016 (147)
47 JJLAB ss2030235483 Sep 14, 2016 (149)
48 ILLUMINA ss2094923550 Dec 20, 2016 (150)
49 ILLUMINA ss2095123141 Dec 20, 2016 (150)
50 ILLUMINA ss2095123142 Dec 20, 2016 (150)
51 USC_VALOUEV ss2158854661 Dec 20, 2016 (150)
52 HUMAN_LONGEVITY ss2247392231 Dec 20, 2016 (150)
53 TOPMED ss2414356611 Dec 20, 2016 (150)
54 SYSTEMSBIOZJU ss2629615033 Nov 08, 2017 (151)
55 ILLUMINA ss2633879488 Nov 08, 2017 (151)
56 GRF ss2704606681 Nov 08, 2017 (151)
57 GNOMAD ss2974467850 Nov 08, 2017 (151)
58 AFFY ss2985238812 Nov 08, 2017 (151)
59 AFFY ss2985855239 Nov 08, 2017 (151)
60 SWEGEN ss3019316664 Nov 08, 2017 (151)
61 ILLUMINA ss3022187001 Nov 08, 2017 (151)
62 BIOINF_KMB_FNS_UNIBA ss3028955013 Nov 08, 2017 (151)
63 CSHL ss3352841760 Nov 08, 2017 (151)
64 TOPMED ss3377368014 Nov 08, 2017 (151)
65 ILLUMINA ss3628536421 Oct 12, 2018 (152)
66 ILLUMINA ss3634868279 Oct 12, 2018 (152)
67 ILLUMINA ss3636564057 Oct 12, 2018 (152)
68 ILLUMINA ss3640575583 Oct 12, 2018 (152)
69 ILLUMINA ss3644800593 Oct 12, 2018 (152)
70 ILLUMINA ss3652650498 Oct 12, 2018 (152)
71 ILLUMINA ss3652650499 Oct 12, 2018 (152)
72 ILLUMINA ss3652650500 Oct 12, 2018 (152)
73 ILLUMINA ss3654006908 Oct 12, 2018 (152)
74 EGCUT_WGS ss3685812198 Jul 13, 2019 (153)
75 EVA_DECODE ss3708217019 Jul 13, 2019 (153)
76 ILLUMINA ss3725969385 Jul 13, 2019 (153)
77 ACPOP ss3743941585 Jul 13, 2019 (153)
78 ILLUMINA ss3744502878 Jul 13, 2019 (153)
79 ILLUMINA ss3745168127 Jul 13, 2019 (153)
80 EVA ss3759393049 Jul 13, 2019 (153)
81 PAGE_CC ss3772092043 Jul 13, 2019 (153)
82 ILLUMINA ss3772664025 Jul 13, 2019 (153)
83 PACBIO ss3788829030 Jul 13, 2019 (153)
84 PACBIO ss3793694338 Jul 13, 2019 (153)
85 PACBIO ss3798580806 Jul 13, 2019 (153)
86 KHV_HUMAN_GENOMES ss3822555780 Jul 13, 2019 (153)
87 EVA ss3835996436 Apr 27, 2020 (154)
88 EVA ss3841626466 Apr 27, 2020 (154)
89 EVA ss3847141543 Apr 27, 2020 (154)
90 SGDP_PRJ ss3890563118 Apr 27, 2020 (154)
91 KRGDB ss3940961836 Apr 27, 2020 (154)
92 KOGIC ss3983655292 Apr 27, 2020 (154)
93 EVA ss3984760639 Apr 26, 2021 (155)
94 EVA ss3985918450 Apr 26, 2021 (155)
95 TOPMED ss5109477650 Apr 26, 2021 (155)
96 TOMMO_GENOMICS ss5232662061 Apr 26, 2021 (155)
97 EVA ss5237617904 Apr 26, 2021 (155)
98 1000Genomes NC_000022.10 - 37551607 Oct 12, 2018 (152)
99 The Avon Longitudinal Study of Parents and Children NC_000022.10 - 37551607 Oct 12, 2018 (152)
100 Chileans NC_000022.10 - 37551607 Apr 27, 2020 (154)
101 Genetic variation in the Estonian population NC_000022.10 - 37551607 Oct 12, 2018 (152)
102 The Danish reference pan genome NC_000022.10 - 37551607 Apr 27, 2020 (154)
103 gnomAD - Genomes NC_000022.11 - 37155567 Apr 26, 2021 (155)
104 Genome of the Netherlands Release 5 NC_000022.10 - 37551607 Apr 27, 2020 (154)
105 HapMap NC_000022.11 - 37155567 Apr 27, 2020 (154)
106 KOREAN population from KRGDB NC_000022.10 - 37551607 Apr 27, 2020 (154)
107 Korean Genome Project NC_000022.11 - 37155567 Apr 27, 2020 (154)
108 Northern Sweden NC_000022.10 - 37551607 Jul 13, 2019 (153)
109 The PAGE Study NC_000022.11 - 37155567 Jul 13, 2019 (153)
110 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000022.10 - 37551607 Apr 26, 2021 (155)
111 CNV burdens in cranial meningiomas NC_000022.10 - 37551607 Apr 26, 2021 (155)
112 Qatari NC_000022.10 - 37551607 Apr 27, 2020 (154)
113 SGDP_PRJ NC_000022.10 - 37551607 Apr 27, 2020 (154)
114 Siberian NC_000022.10 - 37551607 Apr 27, 2020 (154)
115 8.3KJPN NC_000022.10 - 37551607 Apr 26, 2021 (155)
116 TopMed NC_000022.11 - 37155567 Apr 26, 2021 (155)
117 UK 10K study - Twins NC_000022.10 - 37551607 Oct 12, 2018 (152)
118 A Vietnamese Genetic Variation Database NC_000022.10 - 37551607 Jul 13, 2019 (153)
119 ALFA NC_000022.11 - 37155567 Apr 26, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs56623062 May 26, 2008 (130)
rs60545792 May 26, 2008 (130)
rs61594783 Feb 27, 2009 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
48139230, ss3940961836 NC_000022.10:37551606:A:C NC_000022.11:37155566:A:C (self)
ss81825708 NC_000022.8:35876106:A:G NC_000022.11:37155566:A:G (self)
ss66054054, ss75963693, ss112647748, ss117405614, ss160879303, ss169257765, ss204089821, ss208835979, ss255904554, ss283638159, ss292762125, ss1699430088, ss1713741863, ss2094923550 NC_000022.9:35881552:A:G NC_000022.11:37155566:A:G (self)
80748454, 44667435, 271498, 31550446, 5921064, 19904197, 48139230, 17226450, 1144377, 310224, 20968420, 42580098, 11371015, 90631368, 44667435, 9854340, ss228683260, ss238071969, ss244189248, ss482566925, ss491571349, ss566645600, ss662575345, ss780686522, ss783360047, ss995359959, ss1082664500, ss1367195224, ss1429259064, ss1579756125, ss1640011239, ss1683005272, ss1752421207, ss1809792533, ss1917955720, ss1938926498, ss1946590884, ss1959980186, ss1969274318, ss2030235483, ss2095123141, ss2095123142, ss2158854661, ss2414356611, ss2629615033, ss2633879488, ss2704606681, ss2974467850, ss2985238812, ss2985855239, ss3019316664, ss3022187001, ss3352841760, ss3628536421, ss3634868279, ss3636564057, ss3640575583, ss3644800593, ss3652650498, ss3652650499, ss3652650500, ss3654006908, ss3685812198, ss3743941585, ss3744502878, ss3745168127, ss3759393049, ss3772664025, ss3788829030, ss3793694338, ss3798580806, ss3835996436, ss3841626466, ss3890563118, ss3940961836, ss3984760639, ss3985918450, ss5232662061, ss5237617904 NC_000022.10:37551606:A:G NC_000022.11:37155566:A:G (self)
570191250, 2257578, 40033293, 1313512, 240228685, 384586597, 11063846766, ss2247392231, ss3028955013, ss3377368014, ss3708217019, ss3725969385, ss3772092043, ss3822555780, ss3847141543, ss3983655292, ss5109477650 NC_000022.11:37155566:A:G NC_000022.11:37155566:A:G (self)
ss11007663, ss13359286 NT_011520.9:16860660:A:G NC_000022.11:37155566:A:G (self)
ss93027, ss8296255, ss44301339, ss69272720, ss81435786, ss157181586, ss244309490 NT_011520.12:16942175:A:G NC_000022.11:37155566:A:G (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

13 citations for rs743777
PMID Title Author Year Journal
18625055 Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis. Marinou I et al. 2008 Arthritis research & therapy
18794857 Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Barton A et al. 2008 Nature genetics
20017963 Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis. Bermejo JL et al. 2009 BMC proceedings
20179739 Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk. Cavanillas ML et al. 2010 European journal of human genetics
20219786 The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register. Plant D et al. 2011 Rheumatology (Oxford, England)
20426808 AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm. Wang Y et al. 2010 BMC research notes
20461788 Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients. Farragher TM et al. 2010 Arthritis care & research
20498205 Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. Plant D et al. 2010 Annals of the rheumatic diseases
20728947 A novel galectin-1 and interleukin 2 receptor β haplotype is associated with autoimmune myasthenia gravis. Pál Z et al. 2010 Journal of neuroimmunology
21658257 The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity. Hollis-Moffatt JE et al. 2011 Arthritis research & therapy
22328738 Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort. Bowes J et al. 2012 Annals of the rheumatic diseases
24751721 Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives. Goeldner I et al. 2014 PloS one
30299251 Clinical and genetic characteristics of ankylosing spondylitis patients with peripheral arthritis at disease onset. Polo Y La Borda J et al. 2019 Clinical and experimental rheumatology
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post596+ae089ad