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dbSNP Short Genetic Variations

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs6445975

Current Build 153

Released July 9, 2019

Organism
Homo sapiens
Position
chr3:58384450 (GRCh38.p12) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
G>T
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.36956 (46405/125568, TOPMED)
G=0.4163 (32764/78702, PAGE_STUDY)
G=0.3731 (11682/31314, GnomAD) (+ 6 more)
G=0.343 (1716/5008, 1000G)
G=0.352 (1579/4480, Estonian)
G=0.312 (1203/3854, ALSPAC)
G=0.299 (1109/3708, TWINSUK)
G=0.36 (215/600, NorthernSweden)
G=0.17 (36/212, Vietnamese)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
PXK : Intron Variant
Publications
31 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p12 chr 3 NC_000003.12:g.58384450G>T
GRCh37.p13 chr 3 NC_000003.11:g.58370177G>T
Gene: PXK, PX domain containing serine/threonine kinase like (plus strand)
Molecule type Change Amino acid[Codon] SO Term
PXK transcript variant 2 NM_001289095.1:c. N/A Intron Variant
PXK transcript variant 3 NM_001289096.1:c. N/A Intron Variant
PXK transcript variant 4 NM_001289098.1:c. N/A Intron Variant
PXK transcript variant 5 NM_001289099.1:c. N/A Intron Variant
PXK transcript variant 6 NM_001289100.1:c. N/A Intron Variant
PXK transcript variant 7 NM_001289101.1:c. N/A Intron Variant
PXK transcript variant 8 NM_001349488.1:c. N/A Intron Variant
PXK transcript variant 9 NM_001349489.1:c. N/A Intron Variant
PXK transcript variant 10 NM_001349490.1:c. N/A Intron Variant
PXK transcript variant 11 NM_001349491.1:c. N/A Intron Variant
PXK transcript variant 12 NM_001349492.1:c. N/A Intron Variant
PXK transcript variant 13 NM_001349493.1:c. N/A Intron Variant
PXK transcript variant 14 NM_001349494.1:c. N/A Intron Variant
PXK transcript variant 15 NM_001349495.1:c. N/A Intron Variant
PXK transcript variant 16 NM_001349496.1:c. N/A Intron Variant
PXK transcript variant 17 NM_001349497.1:c. N/A Intron Variant
PXK transcript variant 18 NM_001349498.1:c. N/A Intron Variant
PXK transcript variant 19 NM_001349499.1:c. N/A Intron Variant
PXK transcript variant 20 NM_001349500.1:c. N/A Intron Variant
PXK transcript variant 21 NM_001349501.1:c. N/A Intron Variant
PXK transcript variant 22 NM_001349502.1:c. N/A Intron Variant
PXK transcript variant 23 NM_001349503.1:c. N/A Intron Variant
PXK transcript variant 24 NM_001349504.1:c. N/A Intron Variant
PXK transcript variant 25 NM_001349506.1:c. N/A Intron Variant
PXK transcript variant 26 NM_001349507.1:c. N/A Intron Variant
PXK transcript variant 27 NM_001349508.1:c. N/A Intron Variant
PXK transcript variant 28 NM_001349509.1:c. N/A Intron Variant
PXK transcript variant 29 NM_001349510.1:c. N/A Intron Variant
PXK transcript variant 30 NM_001349511.1:c. N/A Intron Variant
PXK transcript variant 31 NM_001349512.1:c. N/A Intron Variant
PXK transcript variant 32 NM_001349513.1:c. N/A Intron Variant
PXK transcript variant 33 NM_001349514.1:c. N/A Intron Variant
PXK transcript variant 34 NM_001349515.1:c. N/A Intron Variant
PXK transcript variant 35 NM_001349516.1:c. N/A Intron Variant
PXK transcript variant 36 NM_001349517.1:c. N/A Intron Variant
PXK transcript variant 37 NM_001349518.1:c. N/A Intron Variant
PXK transcript variant 38 NM_001349519.1:c. N/A Intron Variant
PXK transcript variant 39 NM_001349520.1:c. N/A Intron Variant
PXK transcript variant 40 NM_001349521.1:c. N/A Intron Variant
PXK transcript variant 41 NM_001349522.1:c. N/A Intron Variant
PXK transcript variant 42 NM_001349524.1:c. N/A Intron Variant
PXK transcript variant 43 NM_001349525.1:c. N/A Intron Variant
PXK transcript variant 44 NM_001349526.1:c. N/A Intron Variant
PXK transcript variant 45 NM_001349527.1:c. N/A Intron Variant
PXK transcript variant 46 NM_001349528.1:c. N/A Intron Variant
PXK transcript variant 47 NM_001349529.1:c. N/A Intron Variant
PXK transcript variant 48 NM_001349530.1:c. N/A Intron Variant
PXK transcript variant 49 NM_001349531.1:c. N/A Intron Variant
PXK transcript variant 50 NM_001349532.1:c. N/A Intron Variant
PXK transcript variant 51 NM_001349533.1:c. N/A Intron Variant
PXK transcript variant 52 NM_001349534.1:c. N/A Intron Variant
PXK transcript variant 53 NM_001349535.1:c. N/A Intron Variant
PXK transcript variant 54 NM_001349536.1:c. N/A Intron Variant
PXK transcript variant 55 NM_001349537.1:c. N/A Intron Variant
PXK transcript variant 56 NM_001349538.1:c. N/A Intron Variant
PXK transcript variant 57 NM_001349539.1:c. N/A Intron Variant
PXK transcript variant 58 NM_001349540.1:c. N/A Intron Variant
PXK transcript variant 1 NM_017771.5:c. N/A Intron Variant
PXK transcript variant 59 NR_146193.1:n. N/A Intron Variant
PXK transcript variant 60 NR_146194.1:n. N/A Intron Variant
PXK transcript variant X1 XM_005265250.4:c. N/A Intron Variant
PXK transcript variant X2 XM_017006678.1:c. N/A Intron Variant
PXK transcript variant X3 XM_017006683.1:c. N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 125568 G=0.36956 T=0.63044
The PAGE Study Global Study-wide 78702 G=0.4163 T=0.5837
The PAGE Study AfricanAmerican Sub 32516 G=0.5457 T=0.4543
The PAGE Study Mexican Sub 10810 G=0.3675 T=0.6325
The PAGE Study Asian Sub 8318 G=0.223 T=0.777
The PAGE Study PuertoRican Sub 7918 G=0.366 T=0.634
The PAGE Study NativeHawaiian Sub 4534 G=0.298 T=0.702
The PAGE Study Cuban Sub 4230 G=0.304 T=0.696
The PAGE Study Dominican Sub 3828 G=0.392 T=0.608
The PAGE Study CentralAmerican Sub 2450 G=0.348 T=0.652
The PAGE Study SouthAmerican Sub 1982 G=0.329 T=0.671
The PAGE Study NativeAmerican Sub 1260 G=0.345 T=0.655
The PAGE Study SouthAsian Sub 856 G=0.25 T=0.75
gnomAD - Genomes Global Study-wide 31314 G=0.3731 T=0.6269
gnomAD - Genomes European Sub 18864 G=0.3145 T=0.6855
gnomAD - Genomes African Sub 8672 G=0.549 T=0.451
gnomAD - Genomes East Asian Sub 1558 G=0.171 T=0.829
gnomAD - Genomes Other Sub 1082 G=0.340 T=0.660
gnomAD - Genomes American Sub 848 G=0.35 T=0.65
gnomAD - Genomes Ashkenazi Jewish Sub 290 G=0.18 T=0.82
1000Genomes Global Study-wide 5008 G=0.343 T=0.657
1000Genomes African Sub 1322 G=0.575 T=0.425
1000Genomes East Asian Sub 1008 G=0.203 T=0.797
1000Genomes Europe Sub 1006 G=0.261 T=0.739
1000Genomes South Asian Sub 978 G=0.25 T=0.75
1000Genomes American Sub 694 G=0.35 T=0.65
Genetic variation in the Estonian population Estonian Study-wide 4480 G=0.352 T=0.648
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 G=0.312 T=0.688
UK 10K study - Twins TWIN COHORT Study-wide 3708 G=0.299 T=0.701
Northern Sweden ACPOP Study-wide 600 G=0.36 T=0.64
A Vietnamese Genetic Variation Database Global Study-wide 212 G=0.17 T=0.83
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement G= T Note
GRCh38.p12 chr 3 NC_000003.12:g.58384450= NC_000003.12:g.58384450G>T
GRCh37.p13 chr 3 NC_000003.11:g.58370177= NC_000003.11:g.58370177G>T
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

141 SubSNP, 9 Frequency submissions
No Submitter Submission ID Date (Build)
1 SC_JCM ss11222410 Jul 11, 2003 (116)
2 WI_SSAHASNP ss11556924 Jul 11, 2003 (116)
3 SC_SNP ss15947263 Feb 27, 2004 (120)
4 CSHL-HAPMAP ss20149806 Feb 27, 2004 (120)
5 SSAHASNP ss21896859 Apr 05, 2004 (121)
6 PERLEGEN ss23748331 Sep 20, 2004 (123)
7 ABI ss44438798 Mar 14, 2006 (126)
8 ILLUMINA ss66814873 Nov 30, 2006 (127)
9 ILLUMINA ss67454931 Nov 30, 2006 (127)
10 ILLUMINA ss67807315 Nov 30, 2006 (127)
11 ILLUMINA ss70864599 May 26, 2008 (130)
12 ILLUMINA ss71452424 May 17, 2007 (127)
13 ILLUMINA ss75844598 Dec 07, 2007 (129)
14 ILLUMINA ss79220533 Dec 15, 2007 (130)
15 KRIBB_YJKIM ss84478256 Dec 15, 2007 (130)
16 BCMHGSC_JDW ss92100434 Mar 24, 2008 (129)
17 HUMANGENOME_JCVI ss96013005 Feb 06, 2009 (130)
18 BGI ss106262372 Feb 06, 2009 (130)
19 1000GENOMES ss110197341 Jan 24, 2009 (130)
20 ILLUMINA-UK ss117093922 Feb 14, 2009 (130)
21 ILLUMINA ss122538635 Dec 01, 2009 (131)
22 ENSEMBL ss135294223 Dec 01, 2009 (131)
23 ENSEMBL ss138881757 Dec 01, 2009 (131)
24 ILLUMINA ss154359707 Dec 01, 2009 (131)
25 GMI ss155510543 Dec 01, 2009 (131)
26 ILLUMINA ss159535941 Dec 01, 2009 (131)
27 ILLUMINA ss160774352 Dec 01, 2009 (131)
28 COMPLETE_GENOMICS ss162162581 Jul 04, 2010 (132)
29 COMPLETE_GENOMICS ss163440630 Jul 04, 2010 (132)
30 COMPLETE_GENOMICS ss166592193 Jul 04, 2010 (132)
31 ILLUMINA ss172122515 Jul 04, 2010 (132)
32 ILLUMINA ss174003372 Jul 04, 2010 (132)
33 BCM-HGSC-SUB ss206134683 Jul 04, 2010 (132)
34 1000GENOMES ss210536038 Jul 14, 2010 (132)
35 1000GENOMES ss220153713 Jul 14, 2010 (132)
36 1000GENOMES ss231832924 Jul 14, 2010 (132)
37 1000GENOMES ss239244643 Jul 15, 2010 (132)
38 BL ss253114253 May 09, 2011 (134)
39 GMI ss277137666 May 04, 2012 (137)
40 GMI ss284651069 Apr 25, 2013 (138)
41 PJP ss292802439 May 09, 2011 (134)
42 ILLUMINA ss481243782 May 04, 2012 (137)
43 ILLUMINA ss481267573 May 04, 2012 (137)
44 ILLUMINA ss482252991 Sep 08, 2015 (146)
45 ILLUMINA ss485417245 May 04, 2012 (137)
46 EXOME_CHIP ss491341730 May 04, 2012 (137)
47 ILLUMINA ss537349730 Sep 08, 2015 (146)
48 TISHKOFF ss556635204 Apr 25, 2013 (138)
49 SSMP ss650314463 Apr 25, 2013 (138)
50 ILLUMINA ss778940001 Sep 08, 2015 (146)
51 ILLUMINA ss780685808 Sep 08, 2015 (146)
52 ILLUMINA ss783154062 Sep 08, 2015 (146)
53 ILLUMINA ss783359311 Sep 08, 2015 (146)
54 ILLUMINA ss784109968 Sep 08, 2015 (146)
55 ILLUMINA ss825551051 Apr 01, 2015 (144)
56 ILLUMINA ss832413315 Sep 08, 2015 (146)
57 ILLUMINA ss833047165 Jul 13, 2019 (153)
58 ILLUMINA ss834401696 Sep 08, 2015 (146)
59 EVA-GONL ss978626013 Aug 21, 2014 (142)
60 JMKIDD_LAB ss1070433197 Aug 21, 2014 (142)
61 1000GENOMES ss1304138405 Aug 21, 2014 (142)
62 HAMMER_LAB ss1397338583 Sep 08, 2015 (146)
63 DDI ss1429429125 Apr 01, 2015 (144)
64 EVA_GENOME_DK ss1579975805 Apr 01, 2015 (144)
65 EVA_DECODE ss1588097591 Apr 01, 2015 (144)
66 EVA_UK10K_ALSPAC ss1607141420 Apr 01, 2015 (144)
67 EVA_UK10K_TWINSUK ss1650135453 Apr 01, 2015 (144)
68 EVA_SVP ss1712578154 Apr 01, 2015 (144)
69 ILLUMINA ss1752477321 Sep 08, 2015 (146)
70 ILLUMINA ss1752477322 Sep 08, 2015 (146)
71 HAMMER_LAB ss1799322706 Sep 08, 2015 (146)
72 ILLUMINA ss1917768841 Feb 12, 2016 (147)
73 WEILL_CORNELL_DGM ss1921865208 Feb 12, 2016 (147)
74 ILLUMINA ss1946085152 Feb 12, 2016 (147)
75 ILLUMINA ss1946085153 Feb 12, 2016 (147)
76 ILLUMINA ss1958568325 Feb 12, 2016 (147)
77 ILLUMINA ss1958568326 Feb 12, 2016 (147)
78 GENOMED ss1969399691 Jul 19, 2016 (147)
79 JJLAB ss2021491433 Sep 14, 2016 (149)
80 ILLUMINA ss2094931673 Dec 20, 2016 (150)
81 ILLUMINA ss2095134082 Dec 20, 2016 (150)
82 ILLUMINA ss2095134083 Dec 20, 2016 (150)
83 USC_VALOUEV ss2149566613 Nov 08, 2017 (151)
84 HUMAN_LONGEVITY ss2251865402 Dec 20, 2016 (150)
85 TOPMED ss2418932336 Dec 20, 2016 (150)
86 SYSTEMSBIOZJU ss2625244490 Nov 08, 2017 (151)
87 ILLUMINA ss2633953384 Nov 08, 2017 (151)
88 ILLUMINA ss2633953385 Nov 08, 2017 (151)
89 ILLUMINA ss2633953386 Nov 08, 2017 (151)
90 ILLUMINA ss2635119355 Nov 08, 2017 (151)
91 GRF ss2704942043 Nov 08, 2017 (151)
92 ILLUMINA ss2710973431 Nov 08, 2017 (151)
93 GNOMAD ss2793357050 Nov 08, 2017 (151)
94 AFFY ss2985259058 Nov 08, 2017 (151)
95 AFFY ss2985877731 Nov 08, 2017 (151)
96 SWEGEN ss2992369665 Nov 08, 2017 (151)
97 ILLUMINA ss3022244628 Nov 08, 2017 (151)
98 ILLUMINA ss3022244629 Nov 08, 2017 (151)
99 BIOINF_KMB_FNS_UNIBA ss3024508063 Nov 08, 2017 (151)
100 CSHL ss3345033374 Nov 08, 2017 (151)
101 TOPMED ss3391485545 Nov 08, 2017 (151)
102 ILLUMINA ss3625816653 Oct 12, 2018 (152)
103 ILLUMINA ss3628669074 Oct 12, 2018 (152)
104 ILLUMINA ss3628669075 Oct 12, 2018 (152)
105 ILLUMINA ss3631899223 Oct 12, 2018 (152)
106 ILLUMINA ss3633293243 Oct 12, 2018 (152)
107 ILLUMINA ss3634010319 Oct 12, 2018 (152)
108 ILLUMINA ss3634897520 Oct 12, 2018 (152)
109 ILLUMINA ss3634897521 Oct 12, 2018 (152)
110 ILLUMINA ss3635694245 Oct 12, 2018 (152)
111 ILLUMINA ss3636592439 Oct 12, 2018 (152)
112 ILLUMINA ss3637446609 Oct 12, 2018 (152)
113 ILLUMINA ss3638417077 Oct 12, 2018 (152)
114 ILLUMINA ss3639211106 Oct 12, 2018 (152)
115 ILLUMINA ss3639623605 Oct 12, 2018 (152)
116 ILLUMINA ss3640604821 Oct 12, 2018 (152)
117 ILLUMINA ss3640604822 Oct 12, 2018 (152)
118 ILLUMINA ss3643373911 Oct 12, 2018 (152)
119 ILLUMINA ss3644817739 Oct 12, 2018 (152)
120 ILLUMINA ss3644817740 Oct 12, 2018 (152)
121 URBANLAB ss3647410536 Oct 12, 2018 (152)
122 ILLUMINA ss3652720149 Oct 12, 2018 (152)
123 ILLUMINA ss3652720150 Oct 12, 2018 (152)
124 ILLUMINA ss3652720151 Oct 12, 2018 (152)
125 ILLUMINA ss3654027555 Oct 12, 2018 (152)
126 EGCUT_WGS ss3660292907 Jul 13, 2019 (153)
127 EVA_DECODE ss3709299620 Jul 13, 2019 (153)
128 ILLUMINA ss3726020209 Jul 13, 2019 (153)
129 ACPOP ss3729914582 Jul 13, 2019 (153)
130 ILLUMINA ss3744215396 Jul 13, 2019 (153)
131 ILLUMINA ss3744512020 Jul 13, 2019 (153)
132 ILLUMINA ss3745197496 Jul 13, 2019 (153)
133 ILLUMINA ss3745197497 Jul 13, 2019 (153)
134 EVA ss3760074291 Jul 13, 2019 (153)
135 PAGE_CC ss3771035451 Jul 13, 2019 (153)
136 ILLUMINA ss3772692921 Jul 13, 2019 (153)
137 ILLUMINA ss3772692922 Jul 13, 2019 (153)
138 PACBIO ss3784323884 Jul 13, 2019 (153)
139 PACBIO ss3789838055 Jul 13, 2019 (153)
140 PACBIO ss3794712026 Jul 13, 2019 (153)
141 KHV_HUMAN_GENOMES ss3803208839 Jul 13, 2019 (153)
142 1000Genomes NC_000003.11 - 58370177 Oct 12, 2018 (152)
143 The Avon Longitudinal Study of Parents and Children NC_000003.11 - 58370177 Oct 12, 2018 (152)
144 Genetic variation in the Estonian population NC_000003.11 - 58370177 Oct 12, 2018 (152)
145 gnomAD - Genomes NC_000003.11 - 58370177 Jul 13, 2019 (153)
146 Northern Sweden NC_000003.11 - 58370177 Jul 13, 2019 (153)
147 The PAGE Study NC_000003.12 - 58384450 Jul 13, 2019 (153)
148 TopMed NC_000003.12 - 58384450 Oct 12, 2018 (152)
149 UK 10K study - Twins NC_000003.11 - 58370177 Oct 12, 2018 (152)
150 A Vietnamese Genetic Variation Database NC_000003.11 - 58370177 Jul 13, 2019 (153)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs60421370 May 26, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
ss3639211106, ss3639623605 NC_000003.9:58345216:G:T NC_000003.12:58384449:G:T (self)
ss92100434, ss110197341, ss117093922, ss162162581, ss163440630, ss166592193, ss206134683, ss210536038, ss253114253, ss277137666, ss284651069, ss292802439, ss481243782, ss825551051, ss1397338583, ss1588097591, ss1712578154, ss2094931673, ss2635119355, ss3643373911 NC_000003.10:58345216:G:T NC_000003.12:58384449:G:T (self)
15331278, 8528709, 6031155, 41922709, 3199447, 8528709, 1851701, ss220153713, ss231832924, ss239244643, ss481267573, ss482252991, ss485417245, ss491341730, ss537349730, ss556635204, ss650314463, ss778940001, ss780685808, ss783154062, ss783359311, ss784109968, ss832413315, ss833047165, ss834401696, ss978626013, ss1070433197, ss1304138405, ss1429429125, ss1579975805, ss1607141420, ss1650135453, ss1752477321, ss1752477322, ss1799322706, ss1917768841, ss1921865208, ss1946085152, ss1946085153, ss1958568325, ss1958568326, ss1969399691, ss2021491433, ss2095134082, ss2095134083, ss2149566613, ss2418932336, ss2625244490, ss2633953384, ss2633953385, ss2633953386, ss2704942043, ss2710973431, ss2793357050, ss2985259058, ss2985877731, ss2992369665, ss3022244628, ss3022244629, ss3345033374, ss3625816653, ss3628669074, ss3628669075, ss3631899223, ss3633293243, ss3634010319, ss3634897520, ss3634897521, ss3635694245, ss3636592439, ss3637446609, ss3638417077, ss3640604821, ss3640604822, ss3644817739, ss3644817740, ss3652720149, ss3652720150, ss3652720151, ss3654027555, ss3660292907, ss3729914582, ss3744215396, ss3744512020, ss3745197496, ss3745197497, ss3760074291, ss3772692921, ss3772692922, ss3784323884, ss3789838055, ss3794712026 NC_000003.11:58370176:G:T NC_000003.12:58384449:G:T (self)
256920, 251978505, ss2251865402, ss3024508063, ss3391485545, ss3647410536, ss3709299620, ss3726020209, ss3771035451, ss3803208839 NC_000003.12:58384449:G:T NC_000003.12:58384449:G:T (self)
ss11222410, ss11556924 NT_005999.15:7307985:G:T NC_000003.12:58384449:G:T (self)
ss15947263, ss20149806, ss21896859 NT_022517.16:58292524:G:T NC_000003.12:58384449:G:T (self)
ss23748331, ss44438798, ss66814873, ss67454931, ss67807315, ss70864599, ss71452424, ss75844598, ss79220533, ss84478256, ss96013005, ss106262372, ss122538635, ss135294223, ss138881757, ss154359707, ss155510543, ss159535941, ss160774352, ss172122515, ss174003372 NT_022517.18:58310176:G:T NC_000003.12:58384449:G:T (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

31 citations for rs6445975
PMID Title Author Year Journal
18853133 Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes. Rafiq S et al. 2008 Diabetologia
19225526 Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese. Yang W et al. 2009 Genes and immunity
19442287 Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study. Suarez-Gestal M et al. 2009 Arthritis research & therapy
19714582 Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors. Suarez-Gestal M et al. 2009 Arthritis and rheumatism
20453842 Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Stahl EA et al. 2010 Nature genetics
20829310 Polymorphisms of PXK are associated with autoantibody production, but not disease risk, of systemic lupus erythematosus in Chinese mainland population. Yu B et al. 2011 Lupus
20848568 Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus. Sanchez E et al. 2010 Arthritis and rheumatism
20881011 Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients. Webb R et al. 2011 Annals of the rheumatic diseases
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Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
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