dbSNP Short Genetic Variations
Welcome to the Reference SNP (rs) Report
All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.
Reference SNP (rs) Report
This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.
rs6313
Current Build 155
Released April 9, 2021
- Organism
- Homo sapiens
- Position
-
chr13:46895805 (GRCh38.p13) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
- Alleles
- G>A / G>C
- Variation Type
- SNV Single Nucleotide Variation
- Frequency
-
A=0.420112 (145567/346496, ALFA)A=0.403094 (106695/264690, TOPMED)A=0.407763 (102506/251386, GnomAD_exome) (+ 26 more)
- Clinical Significance
- Reported in ClinVar
- Gene : Consequence
- HTR2A : Synonymous Variant
- Publications
- 148 citations
- Genomic View
- See rs on genome
ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.
Release Version: 20201027095038
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|
| Total | Global | 346496 | G=0.579888 | A=0.420112 |
| European | Sub | 301618 | G=0.579657 | A=0.420343 |
| African | Sub | 12322 | G=0.61516 | A=0.38484 |
| African Others | Sub | 422 | G=0.640 | A=0.360 |
| African American | Sub | 11900 | G=0.61429 | A=0.38571 |
| Asian | Sub | 4042 | G=0.4485 | A=0.5515 |
| East Asian | Sub | 3236 | G=0.4753 | A=0.5247 |
| Other Asian | Sub | 806 | G=0.341 | A=0.659 |
| Latin American 1 | Sub | 1574 | G=0.5762 | A=0.4238 |
| Latin American 2 | Sub | 5336 | G=0.6497 | A=0.3503 |
| South Asian | Sub | 5238 | G=0.5926 | A=0.4074 |
| Other | Sub | 16366 | G=0.56355 | A=0.43645 |
Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").
Download| Study | Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| TopMed | Global | Study-wide | 264690 | G=0.596906 | A=0.403094 |
| gnomAD - Exomes | Global | Study-wide | 251386 | G=0.592237 | A=0.407763 |
| gnomAD - Exomes | European | Sub | 135320 | G=0.602217 | A=0.397783 |
| gnomAD - Exomes | Asian | Sub | 49004 | G=0.51888 | A=0.48112 |
| gnomAD - Exomes | American | Sub | 34588 | G=0.66980 | A=0.33020 |
| gnomAD - Exomes | African | Sub | 16254 | G=0.62440 | A=0.37560 |
| gnomAD - Exomes | Ashkenazi Jewish | Sub | 10080 | G=0.50030 | A=0.49970 |
| gnomAD - Exomes | Other | Sub | 6140 | G=0.5866 | A=0.4134 |
| gnomAD - Genomes | Global | Study-wide | 140002 | G=0.602141 | A=0.397859 |
| gnomAD - Genomes | European | Sub | 75840 | G=0.60282 | A=0.39718 |
| gnomAD - Genomes | African | Sub | 41934 | G=0.62379 | A=0.37621 |
| gnomAD - Genomes | American | Sub | 13628 | G=0.60787 | A=0.39213 |
| gnomAD - Genomes | Ashkenazi Jewish | Sub | 3318 | G=0.5036 | A=0.4964 |
| gnomAD - Genomes | East Asian | Sub | 3130 | G=0.3914 | A=0.6086 |
| gnomAD - Genomes | Other | Sub | 2152 | G=0.5785 | A=0.4215 |
| ExAC | Global | Study-wide | 121344 | G=0.592852 | A=0.407148 |
| ExAC | Europe | Sub | 73318 | G=0.59793 | A=0.40207 |
| ExAC | Asian | Sub | 25148 | G=0.52613 | A=0.47387 |
| ExAC | American | Sub | 11566 | G=0.67361 | A=0.32639 |
| ExAC | African | Sub | 10404 | G=0.62860 | A=0.37140 |
| ExAC | Other | Sub | 908 | G=0.593 | A=0.407 |
| The PAGE Study | Global | Study-wide | 78702 | G=0.59155 | A=0.40845 |
| The PAGE Study | AfricanAmerican | Sub | 32516 | G=0.61957 | A=0.38043 |
| The PAGE Study | Mexican | Sub | 10810 | G=0.65532 | A=0.34468 |
| The PAGE Study | Asian | Sub | 8318 | G=0.4907 | A=0.5093 |
| The PAGE Study | PuertoRican | Sub | 7918 | G=0.6072 | A=0.3928 |
| The PAGE Study | NativeHawaiian | Sub | 4534 | G=0.3476 | A=0.6524 |
| The PAGE Study | Cuban | Sub | 4230 | G=0.5492 | A=0.4508 |
| The PAGE Study | Dominican | Sub | 3828 | G=0.6003 | A=0.3997 |
| The PAGE Study | CentralAmerican | Sub | 2450 | G=0.6641 | A=0.3359 |
| The PAGE Study | SouthAmerican | Sub | 1982 | G=0.6655 | A=0.3345 |
| The PAGE Study | NativeAmerican | Sub | 1260 | G=0.6222 | A=0.3778 |
| The PAGE Study | SouthAsian | Sub | 856 | G=0.595 | A=0.405 |
| 8.3KJPN | JAPANESE | Study-wide | 16760 | G=0.48675 | A=0.51325 |
| GO Exome Sequencing Project | Global | Study-wide | 13006 | G=0.59934 | A=0.40066 |
| GO Exome Sequencing Project | European American | Sub | 8600 | G=0.5899 | A=0.4101 |
| GO Exome Sequencing Project | African American | Sub | 4406 | G=0.6178 | A=0.3822 |
| 1000Genomes | Global | Study-wide | 5008 | G=0.5587 | A=0.4413 |
| 1000Genomes | African | Sub | 1322 | G=0.6074 | A=0.3926 |
| 1000Genomes | East Asian | Sub | 1008 | G=0.4117 | A=0.5883 |
| 1000Genomes | Europe | Sub | 1006 | G=0.5636 | A=0.4364 |
| 1000Genomes | South Asian | Sub | 978 | G=0.578 | A=0.422 |
| 1000Genomes | American | Sub | 694 | G=0.646 | A=0.354 |
| Genetic variation in the Estonian population | Estonian | Study-wide | 4480 | G=0.6705 | A=0.3295 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | G=0.5869 | A=0.4131 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | G=0.5941 | A=0.4059 |
| KOREAN population from KRGDB | KOREAN | Study-wide | 2930 | G=0.5020 | A=0.4980, C=0.0000 |
| HGDP-CEPH-db Supplement 1 | Global | Study-wide | 2082 | G=0.6009 | A=0.3991 |
| HGDP-CEPH-db Supplement 1 | Est_Asia | Sub | 468 | G=0.549 | A=0.451 |
| HGDP-CEPH-db Supplement 1 | Central_South_Asia | Sub | 414 | G=0.623 | A=0.377 |
| HGDP-CEPH-db Supplement 1 | Middle_Est | Sub | 350 | G=0.497 | A=0.503 |
| HGDP-CEPH-db Supplement 1 | Europe | Sub | 320 | G=0.572 | A=0.428 |
| HGDP-CEPH-db Supplement 1 | Africa | Sub | 242 | G=0.740 | A=0.260 |
| HGDP-CEPH-db Supplement 1 | America | Sub | 216 | G=0.764 | A=0.236 |
| HGDP-CEPH-db Supplement 1 | Oceania | Sub | 72 | G=0.49 | A=0.51 |
| HapMap | Global | Study-wide | 1890 | G=0.5799 | A=0.4201 |
| HapMap | American | Sub | 768 | G=0.530 | A=0.470 |
| HapMap | African | Sub | 692 | G=0.695 | A=0.305 |
| HapMap | Asian | Sub | 254 | G=0.476 | A=0.524 |
| HapMap | Europe | Sub | 176 | G=0.494 | A=0.506 |
| Genome of the Netherlands Release 5 | Genome of the Netherlands | Study-wide | 998 | G=0.600 | A=0.400 |
| CNV burdens in cranial meningiomas | Global | Study-wide | 788 | G=0.464 | A=0.536 |
| CNV burdens in cranial meningiomas | CRM | Sub | 788 | G=0.464 | A=0.536 |
| PharmGKB Aggregated | Global | Study-wide | 770 | G=0.655 | A=0.345 |
| PharmGKB Aggregated | PA135348369 | Sub | 386 | G=0.588 | A=0.412 |
| PharmGKB Aggregated | PA128735364 | Sub | 384 | G=0.721 | A=0.279 |
| Chileans | Chilean | Study-wide | 626 | G=0.649 | A=0.351 |
| A Vietnamese Genetic Variation Database | Global | Study-wide | 612 | G=0.266 | A=0.734 |
| Northern Sweden | ACPOP | Study-wide | 600 | G=0.677 | A=0.323 |
| Medical Genome Project healthy controls from Spanish population | Spanish controls | Study-wide | 534 | G=0.560 | A=0.440 |
| SGDP_PRJ | Global | Study-wide | 396 | G=0.366 | A=0.634 |
| FINRISK | Finnish from FINRISK project | Study-wide | 304 | G=0.664 | A=0.336 |
| Qatari | Global | Study-wide | 216 | G=0.500 | A=0.500 |
| Ancient Sardinia genome-wide 1240k capture data generation and analysis | Global | Study-wide | 48 | G=0.58 | A=0.42 |
| The Danish reference pan genome | Danish | Study-wide | 40 | G=0.65 | A=0.35 |
| Siberian | Global | Study-wide | 30 | G=0.43 | A=0.57 |
Help
Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.
Genomic Placements
| Sequence name | Change |
|---|---|
| GRCh38.p13 chr 13 | NC_000013.11:g.46895805G>A |
| GRCh38.p13 chr 13 | NC_000013.11:g.46895805G>C |
| GRCh37.p13 chr 13 | NC_000013.10:g.47469940G>A |
| GRCh37.p13 chr 13 | NC_000013.10:g.47469940G>C |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.6230C>T |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.6230C>G |
Gene: HTR2A, 5-hydroxytryptamine receptor 2A
(minus strand)
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| HTR2A transcript variant 2 |
NM_001165947.5:c.-78+869C… NM_001165947.5:c.-78+869C>T |
N/A | Intron Variant |
| HTR2A transcript variant 3 | NM_001378924.1:c.102C>T | S [TCC] > S [TCT] | Coding Sequence Variant |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_001365853.1:p.Ser34= | S (Ser) > S (Ser) | Synonymous Variant |
| HTR2A transcript variant 3 | NM_001378924.1:c.102C>G | S [TCC] > S [TCG] | Coding Sequence Variant |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_001365853.1:p.Ser34= | S (Ser) > S (Ser) | Synonymous Variant |
| HTR2A transcript variant 1 | NM_000621.5:c.102C>T | S [TCC] > S [TCT] | Coding Sequence Variant |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_000612.1:p.Ser34= | S (Ser) > S (Ser) | Synonymous Variant |
| HTR2A transcript variant 1 | NM_000621.5:c.102C>G | S [TCC] > S [TCG] | Coding Sequence Variant |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_000612.1:p.Ser34= | S (Ser) > S (Ser) | Synonymous Variant |
Help
Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.
Allele: G= (allele ID:
504273
)
| ClinVar Accession | Disease Names | Clinical Significance |
|---|---|---|
| RCV000615738.1 | not specified | Benign |
Allele: A (allele ID:
504274
)
| ClinVar Accession | Disease Names | Clinical Significance |
|---|---|---|
| RCV000615560.1 | not specified | Likely-Benign |
Help
Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".
| Placement | G= | A | C |
|---|---|---|---|
| GRCh38.p13 chr 13 | NC_000013.11:g.46895805= | NC_000013.11:g.46895805G>A | NC_000013.11:g.46895805G>C |
| GRCh37.p13 chr 13 | NC_000013.10:g.47469940= | NC_000013.10:g.47469940G>A | NC_000013.10:g.47469940G>C |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.6230= | NG_013011.1:g.6230C>T | NG_013011.1:g.6230C>G |
| HTR2A transcript variant 1 | NM_000621.5:c.102= | NM_000621.5:c.102C>T | NM_000621.5:c.102C>G |
| HTR2A transcript variant 1 | NM_000621.4:c.102= | NM_000621.4:c.102C>T | NM_000621.4:c.102C>G |
| HTR2A transcript variant 3 | NM_001378924.1:c.102= | NM_001378924.1:c.102C>T | NM_001378924.1:c.102C>G |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_000612.1:p.Ser34= | NP_000612.1:p.Ser34= | NP_000612.1:p.Ser34= |
| 5-hydroxytryptamine receptor 2A isoform 1 | NP_001365853.1:p.Ser34= | NP_001365853.1:p.Ser34= | NP_001365853.1:p.Ser34= |
| HTR2A transcript variant 2 | NM_001165947.2:c.160+869= | NM_001165947.2:c.160+869C>T | NM_001165947.2:c.160+869C>G |
| HTR2A transcript variant 2 | NM_001165947.5:c.-78+869= | NM_001165947.5:c.-78+869C>T | NM_001165947.5:c.-78+869C>G |
Help
Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.
155 SubSNP,
28 Frequency,
2 ClinVar
submissions
| No | Submitter | Submission ID | Date (Build) |
|---|---|---|---|
| 1 | WIAF-CSNP | ss7941 | Sep 19, 2000 (52) |
| 2 | YUSUKE | ss4928286 | Aug 28, 2002 (108) |
| 3 | BCM_SSAHASNP | ss11087375 | Jul 11, 2003 (116) |
| 4 | SC_SNP | ss13329237 | Dec 05, 2003 (119) |
| 5 | CSHL-HAPMAP | ss19284906 | Feb 27, 2004 (120) |
| 6 | SSAHASNP | ss21114665 | Apr 05, 2004 (121) |
| 7 | IMCJ-GDT | ss22887275 | Apr 05, 2004 (121) |
| 8 | PERLEGEN | ss24432440 | Sep 20, 2004 (123) |
| 9 | ABI | ss43518106 | Mar 13, 2006 (126) |
| 10 | APPLERA_GI | ss48401253 | Mar 13, 2006 (126) |
| 11 | AFFY | ss66385828 | Nov 30, 2006 (127) |
| 12 | ILLUMINA | ss67449452 | Nov 30, 2006 (127) |
| 13 | ILLUMINA | ss67800927 | Nov 30, 2006 (127) |
| 14 | ILLUMINA | ss68249907 | Dec 12, 2006 (127) |
| 15 | PERLEGEN | ss69133992 | May 17, 2007 (127) |
| 16 | PHARMGKB_COBRA | ss69365471 | May 17, 2007 (127) |
| 17 | PHARMGKB_MGHB | ss69369851 | May 17, 2007 (127) |
| 18 | ILLUMINA | ss70861829 | May 23, 2008 (130) |
| 19 | ILLUMINA | ss71449228 | May 17, 2007 (127) |
| 20 | ILLUMINA | ss75797443 | Dec 06, 2007 (129) |
| 21 | AFFY | ss76123142 | Dec 08, 2007 (129) |
| 22 | CGM_KYOTO | ss76876609 | Dec 06, 2007 (129) |
| 23 | HGSV | ss78436288 | Dec 06, 2007 (129) |
| 24 | KRIBB_YJKIM | ss80728686 | Dec 14, 2007 (130) |
| 25 | KRIBB_YJKIM | ss83347160 | Dec 14, 2007 (130) |
| 26 | HGSV | ss85708773 | Dec 14, 2007 (130) |
| 27 | BGI | ss103118543 | Dec 01, 2009 (131) |
| 28 | 1000GENOMES | ss112759788 | Jan 25, 2009 (130) |
| 29 | ENSEMBL | ss132226873 | Dec 01, 2009 (131) |
| 30 | ILLUMINA | ss154356859 | Dec 01, 2009 (131) |
| 31 | ILLUMINA | ss159533122 | Dec 01, 2009 (131) |
| 32 | SEATTLESEQ | ss159728196 | Dec 01, 2009 (131) |
| 33 | ILLUMINA | ss160770160 | Dec 01, 2009 (131) |
| 34 | COMPLETE_GENOMICS | ss168060617 | Jul 04, 2010 (132) |
| 35 | COMPLETE_GENOMICS | ss171132004 | Jul 04, 2010 (132) |
| 36 | AFFY | ss172573020 | Jul 04, 2010 (132) |
| 37 | ILLUMINA | ss173992979 | Jul 04, 2010 (132) |
| 38 | BUSHMAN | ss199176330 | Jul 04, 2010 (132) |
| 39 | 1000GENOMES | ss211400964 | Jul 14, 2010 (132) |
| 40 | 1000GENOMES | ss226173745 | Jul 14, 2010 (132) |
| 41 | 1000GENOMES | ss236243603 | Jul 15, 2010 (132) |
| 42 | 1000GENOMES | ss242742020 | Jul 15, 2010 (132) |
| 43 | BL | ss254991364 | May 09, 2011 (134) |
| 44 | GMI | ss281705521 | May 04, 2012 (137) |
| 45 | PJP | ss291436712 | May 09, 2011 (134) |
| 46 | NHLBI-ESP | ss342376800 | May 09, 2011 (134) |
| 47 | ILLUMINA | ss481230402 | May 04, 2012 (137) |
| 48 | ILLUMINA | ss481253970 | May 04, 2012 (137) |
| 49 | ILLUMINA | ss482240305 | Sep 08, 2015 (146) |
| 50 | ILLUMINA | ss485410546 | May 04, 2012 (137) |
| 51 | 1000GENOMES | ss491059930 | May 04, 2012 (137) |
| 52 | CLINSEQ_SNP | ss491679646 | May 04, 2012 (137) |
| 53 | ILLUMINA | ss537344721 | Sep 08, 2015 (146) |
| 54 | TISHKOFF | ss563654819 | Apr 25, 2013 (138) |
| 55 | SSMP | ss659257772 | Apr 25, 2013 (138) |
| 56 | ILLUMINA | ss778566873 | Aug 21, 2014 (142) |
| 57 | ILLUMINA | ss783150725 | Aug 21, 2014 (142) |
| 58 | ILLUMINA | ss784106692 | Aug 21, 2014 (142) |
| 59 | ILLUMINA | ss832409918 | Apr 01, 2015 (144) |
| 60 | ILLUMINA | ss833044360 | Aug 21, 2014 (142) |
| 61 | ILLUMINA | ss833635188 | Aug 21, 2014 (142) |
| 62 | ILLUMINA | ss834023851 | Aug 21, 2014 (142) |
| 63 | JMKIDD_LAB | ss974486767 | Aug 21, 2014 (142) |
| 64 | EVA-GONL | ss990366784 | Aug 21, 2014 (142) |
| 65 | JMKIDD_LAB | ss1067541410 | Aug 21, 2014 (142) |
| 66 | JMKIDD_LAB | ss1079068012 | Aug 21, 2014 (142) |
| 67 | 1000GENOMES | ss1348131544 | Aug 21, 2014 (142) |
| 68 | DDI | ss1427181433 | Apr 01, 2015 (144) |
| 69 | EVA_GENOME_DK | ss1576773713 | Apr 01, 2015 (144) |
| 70 | EVA_FINRISK | ss1584087000 | Apr 01, 2015 (144) |
| 71 | EVA_UK10K_ALSPAC | ss1630233263 | Apr 01, 2015 (144) |
| 72 | EVA_UK10K_TWINSUK | ss1673227296 | Apr 01, 2015 (144) |
| 73 | EVA_DECODE | ss1684889646 | Apr 01, 2015 (144) |
| 74 | EVA_EXAC | ss1691285818 | Apr 01, 2015 (144) |
| 75 | EVA_MGP | ss1711356898 | Apr 01, 2015 (144) |
| 76 | EVA_SVP | ss1713389815 | Apr 01, 2015 (144) |
| 77 | ILLUMINA | ss1752106220 | Sep 08, 2015 (146) |
| 78 | HAMMER_LAB | ss1807600737 | Sep 08, 2015 (146) |
| 79 | WEILL_CORNELL_DGM | ss1933735284 | Feb 12, 2016 (147) |
| 80 | ILLUMINA | ss1946360713 | Feb 12, 2016 (147) |
| 81 | ILLUMINA | ss1959500154 | Feb 12, 2016 (147) |
| 82 | GENOMED | ss1967777562 | Jul 19, 2016 (147) |
| 83 | JJLAB | ss2027626963 | Sep 14, 2016 (149) |
| 84 | ILLUMINA | ss2094795216 | Dec 20, 2016 (150) |
| 85 | ILLUMINA | ss2095045200 | Dec 20, 2016 (150) |
| 86 | USC_VALOUEV | ss2155992840 | Dec 20, 2016 (150) |
| 87 | HUMAN_LONGEVITY | ss2196140023 | Dec 20, 2016 (150) |
| 88 | TOPMED | ss2360268665 | Dec 20, 2016 (150) |
| 89 | SYSTEMSBIOZJU | ss2628303782 | Nov 08, 2017 (151) |
| 90 | ILLUMINA | ss2633061823 | Nov 08, 2017 (151) |
| 91 | GRF | ss2700372081 | Nov 08, 2017 (151) |
| 92 | ILLUMINA | ss2710782604 | Nov 08, 2017 (151) |
| 93 | GNOMAD | ss2740406933 | Nov 08, 2017 (151) |
| 94 | GNOMAD | ss2749044938 | Nov 08, 2017 (151) |
| 95 | GNOMAD | ss2919384773 | Nov 08, 2017 (151) |
| 96 | AFFY | ss2985003437 | Nov 08, 2017 (151) |
| 97 | AFFY | ss2985639041 | Nov 08, 2017 (151) |
| 98 | SWEGEN | ss3010982208 | Nov 08, 2017 (151) |
| 99 | ILLUMINA | ss3021506822 | Nov 08, 2017 (151) |
| 100 | EVA_SAMSUNG_MC | ss3023068282 | Nov 08, 2017 (151) |
| 101 | BIOINF_KMB_FNS_UNIBA | ss3027630723 | Nov 08, 2017 (151) |
| 102 | TOPMED | ss3192080461 | Nov 08, 2017 (151) |
| 103 | CSHL | ss3350444654 | Nov 08, 2017 (151) |
| 104 | ILLUMINA | ss3625643297 | Oct 12, 2018 (152) |
| 105 | ILLUMINA | ss3627061172 | Oct 12, 2018 (152) |
| 106 | ILLUMINA | ss3631065268 | Oct 12, 2018 (152) |
| 107 | ILLUMINA | ss3633049599 | Oct 12, 2018 (152) |
| 108 | ILLUMINA | ss3633751912 | Oct 12, 2018 (152) |
| 109 | ILLUMINA | ss3634544208 | Oct 12, 2018 (152) |
| 110 | ILLUMINA | ss3635442007 | Oct 12, 2018 (152) |
| 111 | ILLUMINA | ss3636231089 | Oct 12, 2018 (152) |
| 112 | ILLUMINA | ss3637193083 | Oct 12, 2018 (152) |
| 113 | ILLUMINA | ss3638010400 | Oct 12, 2018 (152) |
| 114 | ILLUMINA | ss3639018178 | Oct 12, 2018 (152) |
| 115 | ILLUMINA | ss3639819111 | Oct 12, 2018 (152) |
| 116 | ILLUMINA | ss3640251538 | Oct 12, 2018 (152) |
| 117 | ILLUMINA | ss3643000176 | Oct 12, 2018 (152) |
| 118 | ILLUMINA | ss3643870140 | Oct 12, 2018 (152) |
| 119 | ILLUMINA | ss3644613749 | Oct 12, 2018 (152) |
| 120 | OMUKHERJEE_ADBS | ss3646453536 | Oct 12, 2018 (152) |
| 121 | URBANLAB | ss3650028418 | Oct 12, 2018 (152) |
| 122 | ILLUMINA | ss3651894386 | Oct 12, 2018 (152) |
| 123 | ILLUMINA | ss3653774267 | Oct 12, 2018 (152) |
| 124 | EGCUT_WGS | ss3678245929 | Jul 13, 2019 (153) |
| 125 | EVA_DECODE | ss3695244526 | Jul 13, 2019 (153) |
| 126 | ILLUMINA | ss3725392879 | Jul 13, 2019 (153) |
| 127 | ACPOP | ss3739726570 | Jul 13, 2019 (153) |
| 128 | ILLUMINA | ss3744111435 | Jul 13, 2019 (153) |
| 129 | ILLUMINA | ss3744844904 | Jul 13, 2019 (153) |
| 130 | EVA | ss3751436455 | Jul 13, 2019 (153) |
| 131 | PAGE_CC | ss3771745489 | Jul 13, 2019 (153) |
| 132 | ILLUMINA | ss3772343974 | Jul 13, 2019 (153) |
| 133 | PACBIO | ss3787451853 | Jul 13, 2019 (153) |
| 134 | PACBIO | ss3792518948 | Jul 13, 2019 (153) |
| 135 | PACBIO | ss3797402750 | Jul 13, 2019 (153) |
| 136 | KHV_HUMAN_GENOMES | ss3816766297 | Jul 13, 2019 (153) |
| 137 | EVA | ss3824809069 | Apr 27, 2020 (154) |
| 138 | EVA | ss3825529111 | Apr 27, 2020 (154) |
| 139 | EVA | ss3825836739 | Apr 27, 2020 (154) |
| 140 | EVA | ss3833534709 | Apr 27, 2020 (154) |
| 141 | EVA | ss3840348206 | Apr 27, 2020 (154) |
| 142 | EVA | ss3845833863 | Apr 27, 2020 (154) |
| 143 | HGDP | ss3847478315 | Apr 27, 2020 (154) |
| 144 | SGDP_PRJ | ss3879928347 | Apr 27, 2020 (154) |
| 145 | KRGDB | ss3928777452 | Apr 27, 2020 (154) |
| 146 | FSA-LAB | ss3984046672 | Apr 26, 2021 (155) |
| 147 | EVA | ss3984680112 | Apr 26, 2021 (155) |
| 148 | EVA | ss3985638430 | Apr 26, 2021 (155) |
| 149 | EVA | ss3986062709 | Apr 26, 2021 (155) |
| 150 | EVA | ss3986601497 | Apr 26, 2021 (155) |
| 151 | EVA | ss4017632269 | Apr 26, 2021 (155) |
| 152 | TOPMED | ss4945468607 | Apr 26, 2021 (155) |
| 153 | TOMMO_GENOMICS | ss5209892048 | Apr 26, 2021 (155) |
| 154 | EVA | ss5236912901 | Apr 26, 2021 (155) |
| 155 | EVA | ss5237223994 | Apr 26, 2021 (155) |
| 156 | 1000Genomes | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 157 | The Avon Longitudinal Study of Parents and Children | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 158 | Chileans | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 159 | Genetic variation in the Estonian population | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 160 | ExAC | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 161 | FINRISK | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 162 | The Danish reference pan genome | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 163 | gnomAD - Genomes | NC_000013.11 - 46895805 | Apr 26, 2021 (155) |
| 164 | gnomAD - Exomes | NC_000013.10 - 47469940 | Jul 13, 2019 (153) |
| 165 | GO Exome Sequencing Project | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 166 | Genome of the Netherlands Release 5 | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 167 | HGDP-CEPH-db Supplement 1 | NC_000013.9 - 46367941 | Apr 27, 2020 (154) |
| 168 | HapMap | NC_000013.11 - 46895805 | Apr 27, 2020 (154) |
| 169 | KOREAN population from KRGDB | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 170 | Medical Genome Project healthy controls from Spanish population | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 171 | Northern Sweden | NC_000013.10 - 47469940 | Jul 13, 2019 (153) |
| 172 | The PAGE Study | NC_000013.11 - 46895805 | Jul 13, 2019 (153) |
| 173 | Ancient Sardinia genome-wide 1240k capture data generation and analysis | NC_000013.10 - 47469940 | Apr 26, 2021 (155) |
| 174 | CNV burdens in cranial meningiomas | NC_000013.10 - 47469940 | Apr 26, 2021 (155) |
| 175 | PharmGKB Aggregated | NC_000013.11 - 46895805 | Apr 27, 2020 (154) |
| 176 | Qatari | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 177 | SGDP_PRJ | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 178 | Siberian | NC_000013.10 - 47469940 | Apr 27, 2020 (154) |
| 179 | 8.3KJPN | NC_000013.10 - 47469940 | Apr 26, 2021 (155) |
| 180 | TopMed | NC_000013.11 - 46895805 | Apr 26, 2021 (155) |
| 181 | UK 10K study - Twins | NC_000013.10 - 47469940 | Oct 12, 2018 (152) |
| 182 | A Vietnamese Genetic Variation Database | NC_000013.10 - 47469940 | Jul 13, 2019 (153) |
| 183 | ALFA | NC_000013.11 - 46895805 | Apr 26, 2021 (155) |
| 184 | ClinVar | RCV000615560.1 | Oct 12, 2018 (152) |
| 185 | ClinVar | RCV000615738.1 | Oct 12, 2018 (152) |
Help
History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).
| Associated ID | History Updated (Build) |
|---|---|
| rs3742280 | Oct 08, 2002 (108) |
| rs17367493 | Oct 08, 2004 (123) |
| rs57425741 | May 23, 2008 (130) |
| rs386602276 | Aug 21, 2014 (142) |
Added to this RefSNP Cluster:
| Submission IDs | Observation SPDI | Canonical SPDI | Source RSIDs |
|---|---|---|---|
| 156207, ss66385828, ss76123142, ss78436288, ss85708773, ss112759788, ss168060617, ss171132004, ss172573020, ss199176330, ss211400964, ss254991364, ss281705521, ss291436712, ss481230402, ss491679646, ss1684889646, ss1713389815, ss3639018178, ss3639819111, ss3643000176, ss3643870140, ss3847478315 | NC_000013.9:46367940:G:A | NC_000013.11:46895804:G:A | (self) |
| 60999381, 33887937, 119963, 23984177, 1614508, 83461, 3289725, 9651768, 1266457, 15119914, 35954846, 472658, 13011435, 864357, 229617, 15777214, 31945327, 8509194, 67861355, 33887937, 7519149, ss226173745, ss236243603, ss242742020, ss342376800, ss481253970, ss482240305, ss485410546, ss491059930, ss537344721, ss563654819, ss659257772, ss778566873, ss783150725, ss784106692, ss832409918, ss833044360, ss833635188, ss834023851, ss974486767, ss990366784, ss1067541410, ss1079068012, ss1348131544, ss1427181433, ss1576773713, ss1584087000, ss1630233263, ss1673227296, ss1691285818, ss1711356898, ss1752106220, ss1807600737, ss1933735284, ss1946360713, ss1959500154, ss1967777562, ss2027626963, ss2094795216, ss2095045200, ss2155992840, ss2360268665, ss2628303782, ss2633061823, ss2700372081, ss2710782604, ss2740406933, ss2749044938, ss2919384773, ss2985003437, ss2985639041, ss3010982208, ss3021506822, ss3023068282, ss3350444654, ss3625643297, ss3627061172, ss3631065268, ss3633049599, ss3633751912, ss3634544208, ss3635442007, ss3636231089, ss3637193083, ss3638010400, ss3640251538, ss3644613749, ss3646453536, ss3651894386, ss3653774267, ss3678245929, ss3739726570, ss3744111435, ss3744844904, ss3751436455, ss3772343974, ss3787451853, ss3792518948, ss3797402750, ss3824809069, ss3825529111, ss3825836739, ss3833534709, ss3840348206, ss3879928347, ss3928777452, ss3984046672, ss3984680112, ss3985638430, ss3986062709, ss3986601497, ss4017632269, ss5209892048 | NC_000013.10:47469939:G:A | NC_000013.11:46895804:G:A | (self) |
| RCV000615560.1, 430054293, 986150, 966958, 2987, 100703099, 161014265, 14508619996, ss2196140023, ss3027630723, ss3192080461, ss3650028418, ss3695244526, ss3725392879, ss3771745489, ss3816766297, ss3845833863, ss4945468607, ss5236912901, ss5237223994 | NC_000013.11:46895804:G:A | NC_000013.11:46895804:G:A | (self) |
| ss11087375, ss13329237 | NT_024524.12:16044431:G:A | NC_000013.11:46895804:G:A | (self) |
| ss19284906, ss21114665 | NT_024524.13:28449940:G:A | NC_000013.11:46895804:G:A | (self) |
| ss7941, ss4928286, ss22887275, ss24432440, ss43518106, ss48401253, ss67449452, ss67800927, ss68249907, ss69133992, ss69365471, ss69369851, ss70861829, ss71449228, ss75797443, ss76876609, ss80728686, ss83347160, ss103118543, ss132226873, ss154356859, ss159533122, ss159728196, ss160770160, ss173992979 | NT_024524.14:28449939:G:A | NC_000013.11:46895804:G:A | (self) |
| 35954846, ss3928777452 | NC_000013.10:47469939:G:C | NC_000013.11:46895804:G:C | (self) |
Help
Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.
148
citations for rs6313
| PMID | Title | Author | Year | Journal |
|---|---|---|---|---|
| 15882913 | The KPNA3 gene may be a susceptibility candidate for schizophrenia. | Wei J et al. | 2005 | Neuroscience research |
| 16272956 | CYP2A6, MAOA, DBH, DRD4, and 5HT2A genotypes, smoking behaviour and cotinine levels in 1518 UK adolescents. | Huang S et al. | 2005 | Pharmacogenetics and genomics |
| 16642436 | Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. | McMahon FJ et al. | 2006 | American journal of human genetics |
| 17000047 | Serotonin 2A receptor gene is associated with personality traits, but not to disorder, in patients with borderline personality disorder. | Ni X et al. | 2006 | Neuroscience letters |
| 17440930 | Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. | Unschuld PG et al. | 2007 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 17521439 | Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach. | Anttila S et al. | 2007 | BMC psychiatry |
| 17590256 | 5-HT2A SNPs and the Temperament and Character Inventory. | Serretti A et al. | 2007 | Progress in neuro-psychopharmacology & biological psychiatry |
| 17601350 | A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. | Harris SE et al. | 2007 | BMC genetics |
| 17964050 | Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients. | Zhang J et al. | 2008 | Progress in neuro-psychopharmacology & biological psychiatry |
| 18006541 | Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis. | Kling A et al. | 2008 | Annals of the rheumatic diseases |
| 18191318 | Association study between obsessive-compulsive disorder and serotonergic candidate genes. | Saiz PA et al. | 2008 | Progress in neuro-psychopharmacology & biological psychiatry |
| 18196244 | Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility. | Tander B et al. | 2008 | Rheumatology international |
| 18712714 | Genetic variation in the serotonin 2A receptor and suicidal ideation in a sample of 270 Irish high-density schizophrenia families. | Fanous AH et al. | 2009 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 18797395 | Association between the A-1438G polymorphism of the serotonin 2A receptor gene and nonimpulsive suicide attempts. | Saiz PA et al. | 2008 | Psychiatric genetics |
| 18801406 | Serotonin 5-HT2A receptor gene variants influence antidepressant response to repeated total sleep deprivation in bipolar depression. | Benedetti F et al. | 2008 | Progress in neuro-psychopharmacology & biological psychiatry |
| 19156168 | Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. | Need AC et al. | 2009 | European journal of human genetics |
| 19184136 | Examination of association of genes in the serotonin system to autism. | Anderson BM et al. | 2009 | Neurogenetics |
| 19197363 | A genome-wide investigation of SNPs and CNVs in schizophrenia. | Need AC et al. | 2009 | PLoS genetics |
| 19379518 | Development of a fingerprinting panel using medically relevant polymorphisms. | Cross DS et al. | 2009 | BMC medical genomics |
| 19387614 | HTR2A A-1438G/T102C polymorphisms predict negative symptoms performance upon aripiprazole treatment in schizophrenic patients. | Chen SF et al. | 2009 | Psychopharmacology |
| 19475583 | A candidate gene study of Tardive dyskinesia in the CATIE schizophrenia trial. | Tsai HT et al. | 2010 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 19545856 | Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study. | Quednow BB et al. | 2009 | Biological psychiatry |
| 19590397 | 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. | Illi A et al. | 2009 | Neuroreport |
| 19647026 | Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes. | Guhathakurta S et al. | 2009 | Neurochemistry international |
| 19693267 | Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. | Roe BE et al. | 2009 | PloS one |
| 19742166 | Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features. | Drago A et al. | 2009 | International journal of environmental research and public health |
| 19897250 | An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population. | Wang S et al. | 2009 | Psychiatry research |
| 19924111 | Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. | Horstmann S et al. | 2010 | Neuropsychopharmacology |
| 19937159 | HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort. | Kishi T et al. | 2010 | Neuromolecular medicine |
| 20008943 | Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study. | Brent D et al. | 2010 | The American journal of psychiatry |
| 20157235 | Genetics of psychosis in Alzheimer's disease: a review. | DeMichele-Sweet MA et al. | 2010 | Journal of Alzheimer's disease |
| 20373668 | Psychiatric pharmacogenomic testing in clinical practice. | Mrazek DA et al. | 2010 | Dialogues in clinical neuroscience |
| 20403506 | Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. | Holliday KL et al. | 2010 | Journal of psychosomatic research |
| 20431430 | The interaction between serotonin receptor 2A and catechol-O-methyltransferase gene polymorphisms is associated with the novelty-seeking subscale impulsiveness. | Salo J et al. | 2010 | Psychiatric genetics |
| 20565774 | Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. | Cross DS et al. | 2010 | BMC genetics |
| 20633049 | Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? | Middeldorp CM et al. | 2010 | Genes, brain, and behavior |
| 20827275 | Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects. | Nakamura Y et al. | 2010 | Journal of human genetics |
| 21049304 | Influence of candidate genes on attention problems in children: a longitudinal study. | van Beijsterveldt CE et al. | 2011 | Behavior genetics |
| 21136126 | Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression. | Andre K et al. | 2010 | Journal of neural transmission (Vienna, Austria |
| 21162693 | Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction. | Zhang JP et al. | 2011 | Expert opinion on drug metabolism & toxicology |
| 21172166 | Pharmacogenetics of antidepressant response. | Porcelli S et al. | 2011 | Journal of psychiatry & neuroscience |
| 21320838 | Variations in 5-HT2A influence spatial cognitive abilities and working memory. | Gong P et al. | 2011 | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques |
| 21333900 | The role of genetics in IBS. | Saito YA et al. | 2011 | Gastroenterology clinics of North America |
| 21621273 | Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report. | Wrzosek M et al. | 2011 | Psychiatry research |
| 21687501 | Pharmacogenetics of antidepressants. | Crisafulli C et al. | 2011 | Frontiers in pharmacology |
| 21711518 | Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms. | Murphy TM et al. | 2011 | Behavioral and brain functions |
| 21728034 | Methamphetamine-associated psychosis. | Grant KM et al. | 2012 | Journal of neuroimmune pharmacology |
| 21905019 | Large candidate gene association study reveals genetic risk factors and therapeutic targets for fibromyalgia. | Smith SB et al. | 2012 | Arthritis and rheumatism |
| 21930285 | The CC genotype in HTR2A T102C polymorphism is associated with behavioral impulsivity in alcohol-dependent patients. | Jakubczyk A et al. | 2012 | Journal of psychiatric research |
| 21966275 | Large-scale gene-centric analysis identifies novel variants for coronary artery disease. | IBC 50K CAD Consortium. et al. | 2011 | PLoS genetics |
| 21969281 | Influence of birth weight on internalizing traits modulated by serotonergic genes. | Broekman BF et al. | 2011 | Pediatrics |
| 22024213 | A novel gene-environment interaction involved in endometriosis. | McCarty CA et al. | 2012 | International journal of gynaecology and obstetrics |
| 22074755 | Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. | Smith SB et al. | 2011 | The journal of pain |
| 22214315 | Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder. | Graw SL et al. | 2012 | Molecular cytogenetics |
| 22545912 | Association of genetic, psychological and behavioral factors with sleep bruxism in a Japanese population. | Abe Y et al. | 2012 | Journal of sleep research |
| 22735397 | Serotonin system gene polymorphisms are associated with impulsivity in a context dependent manner. | Stoltenberg SF et al. | 2012 | Progress in neuro-psychopharmacology & biological psychiatry |
| 22751492 | Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations. | Ben-Efraim YJ et al. | 2013 | Molecular psychiatry |
| 22893819 | Stress, vulnerability and resilience, a developmental approach. | Broekman BF et al. | 2011 | European journal of psychotraumatology |
| 22933845 | Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse. | Herman AI et al. | 2012 | Substance abuse and rehabilitation |
| 23245538 | Association of candidate gene polymorphisms with diastolic blood pressure change in patients treated with duloxetine. | Fijal BA et al. | 2013 | Psychiatry research |
| 23321485 | The CC genotype in the T102C HTR2A polymorphism predicts relapse in individuals after alcohol treatment. | Jakubczyk A et al. | 2013 | Journal of psychiatric research |
| 23397970 | Interpersonal and genetic origins of adult attachment styles: a longitudinal study from infancy to early adulthood. | Fraley RC et al. | 2013 | Journal of personality and social psychology |
| 23429840 | Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease. | Takahashi H et al. | 2011 | Clinical psychopharmacology and neuroscience |
| 23499153 | Genetic polymorphisms of serotonin transporter and receptor 1A could influence success during embryo implantation and maintenance of pregnancy. | Palomares AR et al. | 2013 | Fertility and sterility |
| 23733030 | Pharmacogenetics in major depression: a comprehensive meta-analysis. | Niitsu T et al. | 2013 | Progress in neuro-psychopharmacology & biological psychiatry |
| 24178752 | Association of the HTR2A gene with alcohol and heroin abuse. | Cao J et al. | 2014 | Human genetics |
| 24801750 | Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder. | Petit AC et al. | 2014 | Progress in neuro-psychopharmacology & biological psychiatry |
| 24881125 | From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment. | Fabbri C et al. | 2014 | Canadian journal of psychiatry. Revue canadienne de psychiatrie |
| 24944790 | Screening for 392 polymorphisms in 141 pharmacogenes. | Kim JY et al. | 2014 | Biomedical reports |
| 25108775 | Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis. | Lin JY et al. | 2014 | Journal of affective disorders |
| 25111588 | Systematic review and metaanalysis of genetic association studies of urinary symptoms and prolapse in women. | Cartwright R et al. | 2015 | American journal of obstetrics and gynecology |
| 25174699 | Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain. | Heddini U et al. | 2014 | The journal of sexual medicine |
| 25223859 | Serotonin risk factors for the development of hypertension in pregnancy. | Sabolovic Rudman S et al. | 2015 | Archives of gynecology and obstetrics |
| 25658328 | Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits. | Banlaki Z et al. | 2015 | PloS one |
| 25733959 | Pharmacogenetics and outcome with antipsychotic drugs. | Pouget JG et al. | 2014 | Dialogues in clinical neuroscience |
| 26044620 | Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction. | Reyes-Gibby CC et al. | 2015 | BMC systems biology |
| 26261165 | Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study. | Basu A et al. | 2015 | The Indian journal of medical research |
| 26322220 | A comprehensive meta-analysis of common genetic variants in autism spectrum conditions. | Warrier V et al. | 2015 | Molecular autism |
| 26390831 | Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways. | Howe AS et al. | 2016 | Molecular psychiatry |
| 26544898 | The impact of serotonin receptor 1A and 2A gene polymorphisms and interactions on suicide attempt and suicide risk in depressed patients with insufficient response to treatment--a European multicentre study. | Höfer P et al. | 2016 | International clinical psychopharmacology |
| 26616111 | Disorder-specific genetic factors in obsessive-compulsive disorder: A comprehensive meta-analysis. | Taylor S et al. | 2016 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 26764241 | Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach. | Qesseveur G et al. | 2016 | Neuropharmacology |
| 26812280 | Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia. | Bani-Fatemi A et al. | 2016 | Neuropsychobiology |
| 26989097 | Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders. | Coleman JR et al. | 2016 | The British journal of psychiatry |
| 27091189 | Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway. | Cocchi E et al. | 2016 | BMC psychiatry |
| 27161551 | Emotion moderates the association between HTR2A (rs6313) genotype and antisaccade latency. | Mills M et al. | 2016 | Experimental brain research |
| 27217270 | Pharmacogenetic Associations of Antipsychotic Drug-Related Weight Gain: A Systematic Review and Meta-analysis. | Zhang JP et al. | 2016 | Schizophrenia bulletin |
| 27325396 | Dopamine D3 receptor Ser9Gly variant is associated with impulse control disorders in Parkinson's disease patients. | Krishnamoorthy S et al. | 2016 | Parkinsonism & related disorders |
| 27375535 | Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review. | Taub DR et al. | 2016 | Frontiers in psychology |
| 27399274 | Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition. | Leamy TE et al. | 2016 | Addictive behaviors |
| 27445478 | 5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients. | Dong ZQ et al. | 2016 | Neuropsychiatric disease and treatment |
| 27445670 | 5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity. | Miller MW et al. | 2016 | Frontiers in neuroscience |
| 27489378 | Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population. | Yücel Y et al. | 2016 | Clinical psychopharmacology and neuroscience |
| 27521242 | TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs. | Xu Z et al. | 2016 | The international journal of neuropsychopharmacology |
| 27529241 | The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key? | Daud AN et al. | 2016 | International journal of molecular sciences |
| 27598719 | Meta-analysis of polymorphism rs6311 and rs6313 in the 5-HT<sub>2A</sub>R gene and schizophrenia. | Sun L et al. | 2017 | Nordic journal of psychiatry |
| 27611726 | Genetic polymorphisms in the serotonergic system are associated with circadian manifestations of bruxism. | Oporto GH 5th et al. | 2016 | Journal of oral rehabilitation |
| 27721799 | Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions. | Mirkovic B et al. | 2016 | Frontiers in psychiatry |
| 27756686 | Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population. | Zhang R et al. | 2016 | Neuroscience letters |
| 27757066 | Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations. | Eum S et al. | 2016 | Dialogues in clinical neuroscience |
| 27853387 | Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics. | Lally J et al. | 2016 | Pharmacogenomics and personalized medicine |
| 27999378 | Effect of 5-HT2A Receptor Polymorphisms, Work Stressors, and Social Support on Job Strain among Petroleum Workers in Xinjiang, China. | Jiang Y et al. | 2016 | International journal of environmental research and public health |
| 28054990 | mRNA Expression and DNA Methylation Analysis of Serotonin Receptor 2A (HTR2A) in the Human Schizophrenic Brain. | Cheah SY et al. | 2017 | Genes |
| 28103253 | Polymorphisms in HTR2A and DRD4 Predispose to Smoking and Smoking Quantity. | Pérez-Rubio G et al. | 2017 | PloS one |
| 28576508 | A review of the role of serotonin system genes in obsessive-compulsive disorder. | Sinopoli VM et al. | 2017 | Neuroscience and biobehavioral reviews |
| 28611364 | Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility. | Zhong Q et al. | 2017 | Scientific reports |
| 28900078 | [Polymorphic Variants of Glutamate Receptor (GRIK5, GRIN2B) and Serotonin Receptor (HTR2A) Genes Are Associated with Chronic Obstructive Pulmonary Disease]. | Korytina GF et al. | 2017 | Molekuliarnaia biologiia |
| 28927418 | A systematic review and integrative approach to decode the common molecular link between levodopa response and Parkinson's disease. | Guin D et al. | 2017 | BMC medical genomics |
| 28951738 | Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders. | Grzesiak M et al. | 2017 | Gastroenterology research and practice |
| 29120849 | Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation. | Gray JC et al. | 2018 | Psychiatry research |
| 29251981 | Hierarchical investigation of genetic influences on response inhibition in healthy young adults. | Weafer J et al. | 2017 | Experimental and clinical psychopharmacology |
| 29331882 | Association analysis of SLC6A4 and HTR2A genes with obsessive-compulsive disorder: Influence of the STin2 polymorphism. | Gomes CKF et al. | 2018 | Comprehensive psychiatry |
| 29526601 | Association between serotonin 2A receptor genetic variations, stressful life events and suicide. | Ghasemi A et al. | 2018 | Gene |
| 29529493 | Does the serotonin receptor gene (rs6313 and rs6314) polymorphism have a role in suicidal attempts? | Atan Y et al. | 2018 | Journal of forensic and legal medicine |
| 29599979 | The phenotype, psychotype and genotype of bruxism. | Cruz-Fierro N et al. | 2018 | Biomedical reports |
| 29602729 | Sperm count and motility are quantitatively affected by functional polymorphisms of HTR2A, MAOA and SLC18A. | Cortés-Rodriguez M et al. | 2018 | Reproductive biomedicine online |
| 29785111 | Association of serotonin receptor 2a haplotypes with obsessive-compulsive disorder and its treatment response in Iranian patients: a genetic and pharmacogenetic study. | Sina M et al. | 2018 | Neuropsychiatric disease and treatment |
| 30093869 | Biological Predictors of Clozapine Response: A Systematic Review. | Samanaite R et al. | 2018 | Frontiers in psychiatry |
| 30178121 | Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample. | Calabrò M et al. | 2018 | Advances in therapy |
| 30375534 | Assessment of Pain Sensitivity in Patients With Chronic Low Back Pain and Association With HTR2A Gene Polymorphism. | Yildiz SH et al. | 2017 | Archives of rheumatology |
| 30389402 | An association study of dopaminergic (DRD2) and serotoninergic (5-HT2) gene polymorphism and schizophrenia in a North Indian population. | Kaur G et al. | 2019 | Asian journal of psychiatry |
| 30486733 | Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers. | D'Agnelli S et al. | 2019 | Molecular pain |
| 30607769 | Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population. | Luo C et al. | 2019 | Neuroscience bulletin |
| 30715578 | Genetic association in female stress urinary incontinence based on proteomic findings: a case-control study. | Reischer T et al. | 2020 | International urogynecology journal |
| 30738094 | Genetic variants as risk factors for cigarette smoking at an early age and relapse to smoking cessation treatment: A pilot study. | Pérez-Rubio G et al. | 2019 | Gene |
| 30789538 | Association of polymorphisms in HTR2A, TPH1, and TPH2 genes with attempted suicide in rural China. | Pan YF et al. | 2019 | Psychiatric genetics |
| 30973927 | Single nucleotide polymorphism analysis in interstitial cystitis/painful bladder syndrome. | Cassão VD et al. | 2019 | PloS one |
| 31061854 | Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment. | Pérez-Rubio G et al. | 2019 | Data in brief |
| 31066578 | Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders. | Poweleit EA et al. | 2019 | Journal of child and adolescent psychopharmacology |
| 31111219 | Genetic endophenotypes for insomnia of major depressive disorder and treatment-induced insomnia. | Badamasi IM et al. | 2019 | Journal of neural transmission (Vienna, Austria |
| 31199591 | Genetic association analysis of 5-HTR2A gene variants in eating disorders in a Mexican population. | Genis-Mendoza AD et al. | 2019 | Brain and behavior |
| 31228794 | A preliminary association study between serotonin transporter (5-HTTLPR), receptor polymorphisms (5-HTR1A, 5-HTR2A) and depression symptom-clusters in a north Indian population suffering from Major Depressive Disorder (MDD). | Basu A et al. | 2019 | Asian journal of psychiatry |
| 31496784 | Association between polymorphisms of <i>LEP, LEPR, DRD2, HTR2A</i> and <i>HTR2C</i> genes and risperidone- or clozapine-induced hyperglycemia. | Puangpetch A et al. | 2019 | Pharmacogenomics and personalized medicine |
| 31721892 | Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial. | Brunoni AR et al. | 2020 | Revista brasileira de psiquiatria (Sao Paulo, Brazil |
| 31767813 | Connection between polymorphisms in <i>HTR2A</i>, <i>TPH2</i>, <i>BDNF</i>, <i>TOMM40</i> genes and the successful mastering of human-computer interfaces. | Turovsky YA et al. | 2019 | Journal of genetics |
| 32146149 | The T102C polymorphism of 5HT2A receptor in oral epithelial dysplasia: A pilot case-control study. | Severo RF et al. | 2020 | Archives of oral biology |
| 32367059 | Genetic basis of sleep bruxism and sleep apnea-response to a medical puzzle. | Wieckiewicz M et al. | 2020 | Scientific reports |
| 32462699 | Association study between HTR2A rs6313 polymorphism and early response to risperidone and olanzapine in schizophrenia patients. | Maffioletti E et al. | 2020 | Drug development research |
| 32553368 | The rs6311 of serotonin receptor 2A (5-HT2A) gene is associated with alexithymia and mental health. | Li X et al. | 2020 | Journal of affective disorders |
| 32569126 | Effect of Caffeine on Endurance Performance in Athletes May Depend on HTR2A and CYP1A2 Genotypes. | Guest NS et al. | 2020 | Journal of strength and conditioning research |
| 32576619 | Effects of <i>TPH2</i> gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders. | Spagnolo PA et al. | 2020 | Journal of neurology, neurosurgery, and psychiatry |
| 32697408 | Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels. | Spies M et al. | 2020 | Human brain mapping |
| 32723321 | The association between serotonin-related gene polymorphisms and susceptibility and early sertraline response in patients with panic disorder. | Zou Z et al. | 2020 | BMC psychiatry |
| 32819202 | Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis. | Du D et al. | 2020 | Pharmacogenomics |
| 32827391 | Pharmacogenetics of antipsychotics in adolescents with acute psychotic episode during first 14 days after admission: effectiveness and safety evaluation. | Ivashchenko DV et al. | 2020 | Drug metabolism and personalized therapy |
| 33171011 | The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients. | Sachau J et al. | 2021 | European journal of pain (London, England) |
| 33244961 | [The role of genetic factors in the development of suicidal behavior in individuals with dependence on synthetic cathinones]. | Gareeva AE et al. | 2020 | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova |
| 33644845 | Association between autism spectrum disorder and polymorphisms in genes encoding serotine and dopamine receptors. | Liu J et al. | 2021 | Metabolic brain disease |
Help
The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.
Genome context:
Select flank length:
Genomic regions, transcripts, and products
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Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.