dbSNP Short Genetic Variations
Welcome to the Reference SNP (rs) Report
All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.
Reference SNP (rs) Report
This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.
rs6311
Current Build 155
Released April 9, 2021
- Organism
- Homo sapiens
- Position
-
chr13:46897343 (GRCh38.p13) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
- Alleles
- C>A / C>T
- Variation Type
- SNV Single Nucleotide Variation
- Frequency
-
T=0.407919 (107972/264690, TOPMED)T=0.417763 (70668/169158, ALFA)T=0.402529 (56309/139888, GnomAD) (+ 18 more)
- Clinical Significance
- Reported in ClinVar
- Gene : Consequence
- HTR2A : Intron Variant
- Publications
- 137 citations
- Genomic View
- See rs on genome
ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.
Release Version: 20201027095038
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|
| Total | Global | 169158 | C=0.582237 | A=0.000000, T=0.417763 |
| European | Sub | 148834 | C=0.579639 | A=0.000000, T=0.420361 |
| African | Sub | 7844 | C=0.6154 | A=0.0000, T=0.3846 |
| African Others | Sub | 270 | C=0.641 | A=0.000, T=0.359 |
| African American | Sub | 7574 | C=0.6145 | A=0.0000, T=0.3855 |
| Asian | Sub | 408 | C=0.400 | A=0.000, T=0.600 |
| East Asian | Sub | 304 | C=0.424 | A=0.000, T=0.576 |
| Other Asian | Sub | 104 | C=0.327 | A=0.000, T=0.673 |
| Latin American 1 | Sub | 408 | C=0.571 | A=0.000, T=0.429 |
| Latin American 2 | Sub | 2590 | C=0.6606 | A=0.0000, T=0.3394 |
| South Asian | Sub | 4982 | C=0.6072 | A=0.0000, T=0.3928 |
| Other | Sub | 4092 | C=0.5525 | A=0.0000, T=0.4475 |
Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").
Download| Study | Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| TopMed | Global | Study-wide | 264690 | C=0.592081 | T=0.407919 |
| gnomAD - Genomes | Global | Study-wide | 139888 | C=0.597471 | T=0.402529 |
| gnomAD - Genomes | European | Sub | 75792 | C=0.60281 | T=0.39719 |
| gnomAD - Genomes | African | Sub | 41872 | C=0.61041 | T=0.38959 |
| gnomAD - Genomes | American | Sub | 13640 | C=0.60220 | T=0.39780 |
| gnomAD - Genomes | Ashkenazi Jewish | Sub | 3322 | C=0.5039 | T=0.4961 |
| gnomAD - Genomes | East Asian | Sub | 3114 | C=0.3895 | T=0.6105 |
| gnomAD - Genomes | Other | Sub | 2148 | C=0.5731 | T=0.4269 |
| The PAGE Study | Global | Study-wide | 78688 | C=0.58348 | T=0.41652 |
| The PAGE Study | AfricanAmerican | Sub | 32516 | C=0.60727 | T=0.39273 |
| The PAGE Study | Mexican | Sub | 10810 | C=0.65560 | T=0.34440 |
| The PAGE Study | Asian | Sub | 8304 | C=0.4906 | T=0.5094 |
| The PAGE Study | PuertoRican | Sub | 7918 | C=0.5874 | T=0.4126 |
| The PAGE Study | NativeHawaiian | Sub | 4534 | C=0.3469 | T=0.6531 |
| The PAGE Study | Cuban | Sub | 4230 | C=0.5454 | T=0.4546 |
| The PAGE Study | Dominican | Sub | 3828 | C=0.5862 | T=0.4138 |
| The PAGE Study | CentralAmerican | Sub | 2450 | C=0.6608 | T=0.3392 |
| The PAGE Study | SouthAmerican | Sub | 1982 | C=0.6630 | T=0.3370 |
| The PAGE Study | NativeAmerican | Sub | 1260 | C=0.6206 | T=0.3794 |
| The PAGE Study | SouthAsian | Sub | 856 | C=0.603 | T=0.397 |
| 8.3KJPN | JAPANESE | Study-wide | 16760 | C=0.48705 | T=0.51295 |
| 1000Genomes | Global | Study-wide | 5008 | C=0.5565 | T=0.4435 |
| 1000Genomes | African | Sub | 1322 | C=0.5908 | T=0.4092 |
| 1000Genomes | East Asian | Sub | 1008 | C=0.4117 | T=0.5883 |
| 1000Genomes | Europe | Sub | 1006 | C=0.5626 | T=0.4374 |
| 1000Genomes | South Asian | Sub | 978 | C=0.595 | T=0.405 |
| 1000Genomes | American | Sub | 694 | C=0.638 | T=0.362 |
| Genetic variation in the Estonian population | Estonian | Study-wide | 4480 | C=0.6683 | T=0.3317 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | C=0.5887 | T=0.4113 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | C=0.5944 | T=0.4056 |
| KOREAN population from KRGDB | KOREAN | Study-wide | 2930 | C=0.5027 | A=0.0000, T=0.4973 |
| HGDP-CEPH-db Supplement 1 | Global | Study-wide | 2084 | C=0.5917 | T=0.4083 |
| HGDP-CEPH-db Supplement 1 | Est_Asia | Sub | 470 | C=0.543 | T=0.457 |
| HGDP-CEPH-db Supplement 1 | Central_South_Asia | Sub | 414 | C=0.643 | T=0.357 |
| HGDP-CEPH-db Supplement 1 | Middle_Est | Sub | 350 | C=0.497 | T=0.503 |
| HGDP-CEPH-db Supplement 1 | Europe | Sub | 320 | C=0.566 | T=0.434 |
| HGDP-CEPH-db Supplement 1 | Africa | Sub | 242 | C=0.649 | T=0.351 |
| HGDP-CEPH-db Supplement 1 | America | Sub | 216 | C=0.764 | T=0.236 |
| HGDP-CEPH-db Supplement 1 | Oceania | Sub | 72 | C=0.49 | T=0.51 |
| HapMap | Global | Study-wide | 1890 | C=0.5683 | T=0.4317 |
| HapMap | American | Sub | 770 | C=0.532 | T=0.468 |
| HapMap | African | Sub | 692 | C=0.662 | T=0.338 |
| HapMap | Asian | Sub | 252 | C=0.468 | T=0.532 |
| HapMap | Europe | Sub | 176 | C=0.500 | T=0.500 |
| Genome of the Netherlands Release 5 | Genome of the Netherlands | Study-wide | 998 | C=0.599 | T=0.401 |
| CNV burdens in cranial meningiomas | Global | Study-wide | 788 | C=0.468 | T=0.532 |
| CNV burdens in cranial meningiomas | CRM | Sub | 788 | C=0.468 | T=0.532 |
| Northern Sweden | ACPOP | Study-wide | 600 | C=0.677 | T=0.323 |
| SGDP_PRJ | Global | Study-wide | 404 | C=0.369 | T=0.631 |
| Qatari | Global | Study-wide | 216 | C=0.495 | T=0.505 |
| A Vietnamese Genetic Variation Database | Global | Study-wide | 210 | C=0.248 | T=0.752 |
| Ancient Sardinia genome-wide 1240k capture data generation and analysis | Global | Study-wide | 94 | C=0.38 | T=0.62 |
| The Danish reference pan genome | Danish | Study-wide | 40 | C=0.65 | T=0.35 |
| Siberian | Global | Study-wide | 30 | C=0.43 | T=0.57 |
Help
Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.
Genomic Placements
| Sequence name | Change |
|---|---|
| GRCh38.p13 chr 13 | NC_000013.11:g.46897343C>A |
| GRCh38.p13 chr 13 | NC_000013.11:g.46897343C>T |
| GRCh37.p13 chr 13 | NC_000013.10:g.47471478C>A |
| GRCh37.p13 chr 13 | NC_000013.10:g.47471478C>T |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.4692G>T |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.4692G>A |
Gene: HTR2A, 5-hydroxytryptamine receptor 2A
(minus strand)
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| HTR2A transcript variant 3 |
NM_001378924.1:c.-329+609… NM_001378924.1:c.-329+609G>T |
N/A | Intron Variant |
| HTR2A transcript variant 1 | NM_000621.5:c. | N/A | Genic Upstream Transcript Variant |
| HTR2A transcript variant 2 | NM_001165947.5:c. | N/A | Genic Upstream Transcript Variant |
Help
Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.
Allele: T (allele ID:
504813
)
| ClinVar Accession | Disease Names | Clinical Significance |
|---|---|---|
| RCV000605277.1 | not specified | Likely-Benign |
| RCV001093594.1 | Cocaine-Related Disorders | Likely-Benign |
Help
Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".
| Placement | C= | A | T |
|---|---|---|---|
| GRCh38.p13 chr 13 | NC_000013.11:g.46897343= | NC_000013.11:g.46897343C>A | NC_000013.11:g.46897343C>T |
| GRCh37.p13 chr 13 | NC_000013.10:g.47471478= | NC_000013.10:g.47471478C>A | NC_000013.10:g.47471478C>T |
| HTR2A RefSeqGene (LRG_1008) | NG_013011.1:g.4692= | NG_013011.1:g.4692G>T | NG_013011.1:g.4692G>A |
| HTR2A transcript variant 3 | NM_001378924.1:c.-329+609= | NM_001378924.1:c.-329+609G>T | NM_001378924.1:c.-329+609G>A |
Help
Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.
122 SubSNP,
21 Frequency,
2 ClinVar
submissions
| No | Submitter | Submission ID | Date (Build) |
|---|---|---|---|
| 1 | WIAF-CSNP | ss7939 | Sep 19, 2000 (52) |
| 2 | TSC-CSHL | ss2099948 | Oct 23, 2000 (88) |
| 3 | SC_JCM | ss5784016 | Feb 20, 2003 (111) |
| 4 | BCM_SSAHASNP | ss11056913 | Jul 11, 2003 (116) |
| 5 | SC_SNP | ss13329238 | Dec 05, 2003 (119) |
| 6 | CSHL-HAPMAP | ss17498388 | Feb 27, 2004 (120) |
| 7 | CSHL-HAPMAP | ss19278078 | Feb 27, 2004 (120) |
| 8 | SSAHASNP | ss21115889 | Apr 05, 2004 (121) |
| 9 | PERLEGEN | ss23991391 | Sep 20, 2004 (123) |
| 10 | STEJUSTINE-REGGEN | ss51853939 | Mar 16, 2006 (126) |
| 11 | ILLUMINA | ss67449420 | Nov 30, 2006 (127) |
| 12 | ILLUMINA | ss67800891 | Nov 30, 2006 (127) |
| 13 | ILLUMINA | ss68249902 | Dec 12, 2006 (127) |
| 14 | ILLUMINA | ss70861814 | May 26, 2008 (130) |
| 15 | ILLUMINA | ss71449210 | May 17, 2007 (127) |
| 16 | ILLUMINA | ss75784706 | Dec 06, 2007 (129) |
| 17 | KRIBB_YJKIM | ss83347152 | Dec 16, 2007 (130) |
| 18 | HUMANGENOME_JCVI | ss97156264 | Feb 06, 2009 (130) |
| 19 | BGI | ss103118544 | Dec 01, 2009 (131) |
| 20 | 1000GENOMES | ss112759807 | Jan 25, 2009 (130) |
| 21 | ENSEMBL | ss132226882 | Dec 01, 2009 (131) |
| 22 | ILLUMINA | ss154356844 | Dec 01, 2009 (131) |
| 23 | ILLUMINA | ss159533108 | Dec 01, 2009 (131) |
| 24 | ILLUMINA | ss160770133 | Dec 01, 2009 (131) |
| 25 | COMPLETE_GENOMICS | ss168060669 | Jul 04, 2010 (132) |
| 26 | COMPLETE_GENOMICS | ss171132048 | Jul 04, 2010 (132) |
| 27 | ILLUMINA | ss173992917 | Jul 04, 2010 (132) |
| 28 | BUSHMAN | ss199176358 | Jul 04, 2010 (132) |
| 29 | 1000GENOMES | ss211400969 | Jul 14, 2010 (132) |
| 30 | 1000GENOMES | ss226173755 | Jul 14, 2010 (132) |
| 31 | 1000GENOMES | ss236243610 | Jul 15, 2010 (132) |
| 32 | 1000GENOMES | ss242742025 | Jul 15, 2010 (132) |
| 33 | BL | ss254991385 | May 09, 2011 (134) |
| 34 | GMI | ss281705525 | May 04, 2012 (137) |
| 35 | PJP | ss291436716 | May 09, 2011 (134) |
| 36 | ILLUMINA | ss481230318 | May 04, 2012 (137) |
| 37 | ILLUMINA | ss481253884 | May 04, 2012 (137) |
| 38 | ILLUMINA | ss482240219 | Sep 08, 2015 (146) |
| 39 | ILLUMINA | ss485410505 | May 04, 2012 (137) |
| 40 | ILLUMINA | ss537344692 | Sep 08, 2015 (146) |
| 41 | TISHKOFF | ss563654829 | Apr 25, 2013 (138) |
| 42 | SSMP | ss659257781 | Apr 25, 2013 (138) |
| 43 | ILLUMINA | ss778566866 | Sep 08, 2015 (146) |
| 44 | ILLUMINA | ss783150704 | Sep 08, 2015 (146) |
| 45 | ILLUMINA | ss784106672 | Sep 08, 2015 (146) |
| 46 | ILLUMINA | ss832409896 | Sep 08, 2015 (146) |
| 47 | ILLUMINA | ss833044346 | Jul 13, 2019 (153) |
| 48 | ILLUMINA | ss834023844 | Sep 08, 2015 (146) |
| 49 | EVA-GONL | ss990366795 | Aug 21, 2014 (142) |
| 50 | JMKIDD_LAB | ss1079068022 | Aug 21, 2014 (142) |
| 51 | 1000GENOMES | ss1348131587 | Aug 21, 2014 (142) |
| 52 | DDI | ss1427181439 | Apr 01, 2015 (144) |
| 53 | EVA_GENOME_DK | ss1576773719 | Apr 01, 2015 (144) |
| 54 | EVA_UK10K_ALSPAC | ss1630233283 | Apr 01, 2015 (144) |
| 55 | EVA_UK10K_TWINSUK | ss1673227316 | Apr 01, 2015 (144) |
| 56 | EVA_DECODE | ss1684889657 | Apr 01, 2015 (144) |
| 57 | EVA_SVP | ss1713389819 | Apr 01, 2015 (144) |
| 58 | ILLUMINA | ss1752106224 | Sep 08, 2015 (146) |
| 59 | HAMMER_LAB | ss1807600745 | Sep 08, 2015 (146) |
| 60 | WEILL_CORNELL_DGM | ss1933735295 | Feb 12, 2016 (147) |
| 61 | ILLUMINA | ss1959500160 | Feb 12, 2016 (147) |
| 62 | GENOMED | ss1967777566 | Jul 19, 2016 (147) |
| 63 | JJLAB | ss2027626970 | Sep 14, 2016 (149) |
| 64 | ILLUMINA | ss2094795217 | Dec 20, 2016 (150) |
| 65 | ILLUMINA | ss2095045201 | Dec 20, 2016 (150) |
| 66 | USC_VALOUEV | ss2155992846 | Dec 20, 2016 (150) |
| 67 | HUMAN_LONGEVITY | ss2196140100 | Dec 20, 2016 (150) |
| 68 | TOPMED | ss2360268752 | Dec 20, 2016 (150) |
| 69 | SYSTEMSBIOZJU | ss2628303786 | Nov 08, 2017 (151) |
| 70 | ILLUMINA | ss2633061828 | Nov 08, 2017 (151) |
| 71 | GRF | ss2700372086 | Nov 08, 2017 (151) |
| 72 | GNOMAD | ss2919384882 | Nov 08, 2017 (151) |
| 73 | AFFY | ss2985003440 | Nov 08, 2017 (151) |
| 74 | AFFY | ss2985639048 | Nov 08, 2017 (151) |
| 75 | SWEGEN | ss3010982218 | Nov 08, 2017 (151) |
| 76 | ILLUMINA | ss3021506826 | Nov 08, 2017 (151) |
| 77 | BIOINF_KMB_FNS_UNIBA | ss3027630728 | Nov 08, 2017 (151) |
| 78 | TOPMED | ss3192080710 | Nov 08, 2017 (151) |
| 79 | CSHL | ss3350444661 | Nov 08, 2017 (151) |
| 80 | ILLUMINA | ss3627061184 | Oct 12, 2018 (152) |
| 81 | ILLUMINA | ss3631065273 | Oct 12, 2018 (152) |
| 82 | ILLUMINA | ss3633049601 | Oct 12, 2018 (152) |
| 83 | ILLUMINA | ss3633751914 | Oct 12, 2018 (152) |
| 84 | ILLUMINA | ss3634544212 | Oct 12, 2018 (152) |
| 85 | ILLUMINA | ss3635442009 | Oct 12, 2018 (152) |
| 86 | ILLUMINA | ss3636231092 | Oct 12, 2018 (152) |
| 87 | ILLUMINA | ss3637193085 | Oct 12, 2018 (152) |
| 88 | ILLUMINA | ss3638010406 | Oct 12, 2018 (152) |
| 89 | ILLUMINA | ss3639018180 | Oct 12, 2018 (152) |
| 90 | ILLUMINA | ss3639819113 | Oct 12, 2018 (152) |
| 91 | ILLUMINA | ss3640251542 | Oct 12, 2018 (152) |
| 92 | ILLUMINA | ss3641041163 | Oct 12, 2018 (152) |
| 93 | ILLUMINA | ss3641336058 | Oct 12, 2018 (152) |
| 94 | ILLUMINA | ss3643000181 | Oct 12, 2018 (152) |
| 95 | ILLUMINA | ss3643870142 | Oct 12, 2018 (152) |
| 96 | URBANLAB | ss3650028422 | Oct 12, 2018 (152) |
| 97 | ILLUMINA | ss3651894390 | Oct 12, 2018 (152) |
| 98 | ILLUMINA | ss3651894391 | Oct 12, 2018 (152) |
| 99 | ILLUMINA | ss3653774270 | Oct 12, 2018 (152) |
| 100 | EGCUT_WGS | ss3678245943 | Jul 13, 2019 (153) |
| 101 | EVA_DECODE | ss3695244544 | Jul 13, 2019 (153) |
| 102 | ILLUMINA | ss3725392883 | Jul 13, 2019 (153) |
| 103 | ACPOP | ss3739726578 | Jul 13, 2019 (153) |
| 104 | ILLUMINA | ss3744844908 | Jul 13, 2019 (153) |
| 105 | EVA | ss3751436465 | Jul 13, 2019 (153) |
| 106 | PAGE_CC | ss3771745494 | Jul 13, 2019 (153) |
| 107 | ILLUMINA | ss3772343978 | Jul 13, 2019 (153) |
| 108 | PACBIO | ss3787451857 | Jul 13, 2019 (153) |
| 109 | PACBIO | ss3792518952 | Jul 13, 2019 (153) |
| 110 | PACBIO | ss3797402754 | Jul 13, 2019 (153) |
| 111 | KHV_HUMAN_GENOMES | ss3816766312 | Jul 13, 2019 (153) |
| 112 | EVA | ss3833534714 | Apr 27, 2020 (154) |
| 113 | EVA | ss3840348211 | Apr 27, 2020 (154) |
| 114 | EVA | ss3845833868 | Apr 27, 2020 (154) |
| 115 | HGDP | ss3847478318 | Apr 27, 2020 (154) |
| 116 | SGDP_PRJ | ss3879928365 | Apr 27, 2020 (154) |
| 117 | KRGDB | ss3928777472 | Apr 27, 2020 (154) |
| 118 | EVA | ss3984680114 | Apr 26, 2021 (155) |
| 119 | EVA | ss3985638434 | Apr 26, 2021 (155) |
| 120 | EVA | ss4017632273 | Apr 26, 2021 (155) |
| 121 | TOPMED | ss4945468980 | Apr 26, 2021 (155) |
| 122 | TOMMO_GENOMICS | ss5209892089 | Apr 26, 2021 (155) |
| 123 | 1000Genomes | NC_000013.10 - 47471478 | Oct 12, 2018 (152) |
| 124 | The Avon Longitudinal Study of Parents and Children | NC_000013.10 - 47471478 | Oct 12, 2018 (152) |
| 125 | Genetic variation in the Estonian population | NC_000013.10 - 47471478 | Oct 12, 2018 (152) |
| 126 | The Danish reference pan genome | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 127 | gnomAD - Genomes | NC_000013.11 - 46897343 | Apr 26, 2021 (155) |
| 128 | Genome of the Netherlands Release 5 | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 129 | HGDP-CEPH-db Supplement 1 | NC_000013.9 - 46369479 | Apr 27, 2020 (154) |
| 130 | HapMap | NC_000013.11 - 46897343 | Apr 27, 2020 (154) |
| 131 | KOREAN population from KRGDB | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 132 | Northern Sweden | NC_000013.10 - 47471478 | Jul 13, 2019 (153) |
| 133 | The PAGE Study | NC_000013.11 - 46897343 | Jul 13, 2019 (153) |
| 134 | Ancient Sardinia genome-wide 1240k capture data generation and analysis | NC_000013.10 - 47471478 | Apr 26, 2021 (155) |
| 135 | CNV burdens in cranial meningiomas | NC_000013.10 - 47471478 | Apr 26, 2021 (155) |
| 136 | Qatari | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 137 | SGDP_PRJ | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 138 | Siberian | NC_000013.10 - 47471478 | Apr 27, 2020 (154) |
| 139 | 8.3KJPN | NC_000013.10 - 47471478 | Apr 26, 2021 (155) |
| 140 | TopMed | NC_000013.11 - 46897343 | Apr 26, 2021 (155) |
| 141 | UK 10K study - Twins | NC_000013.10 - 47471478 | Oct 12, 2018 (152) |
| 142 | A Vietnamese Genetic Variation Database | NC_000013.10 - 47471478 | Jul 13, 2019 (153) |
| 143 | ALFA | NC_000013.11 - 46897343 | Apr 26, 2021 (155) |
| 144 | ClinVar | RCV000605277.1 | Oct 12, 2018 (152) |
| 145 | ClinVar | RCV001093594.1 | Apr 26, 2021 (155) |
Help
History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).
| Associated ID | History Updated (Build) |
|---|---|
| rs36213154 | Oct 25, 2006 (127) |
| rs61203218 | May 26, 2008 (130) |
Added to this RefSNP Cluster:
| Submission IDs | Observation SPDI | Canonical SPDI | Source RSIDs |
|---|---|---|---|
| 35954866, ss3928777472 | NC_000013.10:47471477:C:A | NC_000013.11:46897342:C:A | (self) |
| 12576181261 | NC_000013.11:46897342:C:A | NC_000013.11:46897342:C:A | |
| 156210, ss112759807, ss168060669, ss171132048, ss199176358, ss211400969, ss254991385, ss281705525, ss291436716, ss481230318, ss1684889657, ss1713389819, ss3639018180, ss3639819113, ss3643000181, ss3643870142, ss3847478318 | NC_000013.9:46369478:C:T | NC_000013.11:46897342:C:T | (self) |
| 60999424, 33887959, 23984191, 3289731, 15119925, 35954866, 13011443, 864361, 229619, 15777225, 31945345, 8509200, 67861396, 33887959, 7519156, ss226173755, ss236243610, ss242742025, ss481253884, ss482240219, ss485410505, ss537344692, ss563654829, ss659257781, ss778566866, ss783150704, ss784106672, ss832409896, ss833044346, ss834023844, ss990366795, ss1079068022, ss1348131587, ss1427181439, ss1576773719, ss1630233283, ss1673227316, ss1752106224, ss1807600745, ss1933735295, ss1959500160, ss1967777566, ss2027626970, ss2094795217, ss2095045201, ss2155992846, ss2360268752, ss2628303786, ss2633061828, ss2700372086, ss2919384882, ss2985003440, ss2985639048, ss3010982218, ss3021506826, ss3350444661, ss3627061184, ss3631065273, ss3633049601, ss3633751914, ss3634544212, ss3635442009, ss3636231092, ss3637193085, ss3638010406, ss3640251542, ss3641041163, ss3641336058, ss3651894390, ss3651894391, ss3653774270, ss3678245943, ss3739726578, ss3744844908, ss3751436465, ss3772343978, ss3787451857, ss3792518952, ss3797402754, ss3833534714, ss3840348211, ss3879928365, ss3928777472, ss3984680114, ss3985638434, ss4017632273, ss5209892089 | NC_000013.10:47471477:C:T | NC_000013.11:46897342:C:T | (self) |
| RCV000605277.1, RCV001093594.1, 430054570, 986163, 966963, 100703325, 161014638, 12576181261, ss2196140100, ss3027630728, ss3192080710, ss3650028422, ss3695244544, ss3725392883, ss3771745494, ss3816766312, ss3845833868, ss4945468980 | NC_000013.11:46897342:C:T | NC_000013.11:46897342:C:T | (self) |
| ss11056913, ss13329238 | NT_024524.12:16045969:C:T | NC_000013.11:46897342:C:T | (self) |
| ss17498388, ss19278078, ss21115889 | NT_024524.13:28451478:C:T | NC_000013.11:46897342:C:T | (self) |
| ss7939, ss2099948, ss5784016, ss23991391, ss51853939, ss67449420, ss67800891, ss68249902, ss70861814, ss71449210, ss75784706, ss83347152, ss97156264, ss103118544, ss132226882, ss154356844, ss159533108, ss160770133, ss173992917 | NT_024524.14:28451477:C:T | NC_000013.11:46897342:C:T | (self) |
Help
Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.
137
citations for rs6311
| PMID | Title | Author | Year | Journal |
|---|---|---|---|---|
| 16642436 | Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. | McMahon FJ et al. | 2006 | American journal of human genetics |
| 16814396 | Anger- and aggression-related traits are associated with polymorphisms in the 5-HT-2A gene. | Giegling I et al. | 2006 | Journal of affective disorders |
| 16876316 | Association study of sporadic Parkinson's disease genetic risk factors in patients from Russia by APEX technology. | Shadrina M et al. | 2006 | Neuroscience letters |
| 17241828 | Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorder. | Dickel DE et al. | 2007 | Biological psychiatry |
| 17440930 | Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. | Unschuld PG et al. | 2007 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 17590256 | 5-HT2A SNPs and the Temperament and Character Inventory. | Serretti A et al. | 2007 | Progress in neuro-psychopharmacology & biological psychiatry |
| 17688403 | Association of serotonin 2A receptor and lack of association of CYP1A2 gene polymorphism with tardive dyskinesia in a Turkish population. | Boke O et al. | 2007 | DNA and cell biology |
| 18006541 | Genetic variations in the serotonin 5-HT2A receptor gene (HTR2A) are associated with rheumatoid arthritis. | Kling A et al. | 2008 | Annals of the rheumatic diseases |
| 18079067 | Genetic evaluation of the serotonergic system in chronic fatigue syndrome. | Smith AK et al. | 2008 | Psychoneuroendocrinology |
| 18081710 | Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression. | Hahn MK et al. | 2008 | Genes, brain, and behavior |
| 18191318 | Association study between obsessive-compulsive disorder and serotonergic candidate genes. | Saiz PA et al. | 2008 | Progress in neuro-psychopharmacology & biological psychiatry |
| 18196244 | Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility. | Tander B et al. | 2008 | Rheumatology international |
| 18439448 | Stress, genes and the biology of suicidal behavior. | Currier D et al. | 2008 | The Psychiatric clinics of North America |
| 18797395 | Association between the A-1438G polymorphism of the serotonin 2A receptor gene and nonimpulsive suicide attempts. | Saiz PA et al. | 2008 | Psychiatric genetics |
| 18826444 | Serotonergic genes and amygdala activity in response to negative affective facial stimuli in Korean women. | Lee BT et al. | 2008 | Genes, brain, and behavior |
| 19328219 | Differential role of serotonergic polymorphisms in alcohol and heroin dependence. | Saiz PA et al. | 2009 | Progress in neuro-psychopharmacology & biological psychiatry |
| 19359258 | Cohort profile: risk patterns and processes for psychopathology emerging during adolescence: the ROOTS project. | Goodyer IM et al. | 2010 | International journal of epidemiology |
| 19545856 | Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study. | Quednow BB et al. | 2009 | Biological psychiatry |
| 19560507 | Interaction of serotonin-related genes affects short-term antidepressant response in major depressive disorder. | Lin E et al. | 2009 | Progress in neuro-psychopharmacology & biological psychiatry |
| 19590397 | 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. | Illi A et al. | 2009 | Neuroreport |
| 19647026 | Analysis of serotonin receptor 2A gene (HTR2A): association study with autism spectrum disorder in the Indian population and investigation of the gene expression in peripheral blood leukocytes. | Guhathakurta S et al. | 2009 | Neurochemistry international |
| 19690620 | Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes. | Kring SI et al. | 2009 | PloS one |
| 19911060 | Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint. | Doi N et al. | 2009 | PloS one |
| 19937159 | HTR2A is associated with SSRI response in major depressive disorder in a Japanese cohort. | Kishi T et al. | 2010 | Neuromolecular medicine |
| 20008943 | Association of FKBP5 polymorphisms with suicidal events in the Treatment of Resistant Depression in Adolescents (TORDIA) study. | Brent D et al. | 2010 | The American journal of psychiatry |
| 20191112 | The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives. | Pinheiro AP et al. | 2009 | International journal of child and adolescent health |
| 20198576 | Association between the -1438A/G polymorphism of the serotonin 2A receptor gene and late-onset psoriasis in a Thai population. | Ronpirin C et al. | 2010 | Genetics and molecular research |
| 20421848 | Interactions between functional serotonergic polymorphisms and demographic factors influence personality traits in healthy Spanish Caucasians. | Saiz PA et al. | 2010 | Psychiatric genetics |
| 20549395 | Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies. | Cornelis MC et al. | 2010 | Current psychiatry reports |
| 20580209 | Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor gene. | Molnar E et al. | 2010 | European neuropsychopharmacology |
| 20633049 | Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? | Middeldorp CM et al. | 2010 | Genes, brain, and behavior |
| 20827275 | Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects. | Nakamura Y et al. | 2010 | Journal of human genetics |
| 20941551 | Functional genomics of serotonin receptor 2A (HTR2A): interaction of polymorphism, methylation, expression and disease association. | Falkenberg VR et al. | 2011 | Neuromolecular medicine |
| 21049304 | Influence of candidate genes on attention problems in children: a longitudinal study. | van Beijsterveldt CE et al. | 2011 | Behavior genetics |
| 21136126 | Temperament profiles, 5-HT2A genotype, and response to treatment with SSRIs in major depression. | Andre K et al. | 2010 | Journal of neural transmission (Vienna, Austria |
| 21162693 | Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction. | Zhang JP et al. | 2011 | Expert opinion on drug metabolism & toxicology |
| 21172166 | Pharmacogenetics of antidepressant response. | Porcelli S et al. | 2011 | Journal of psychiatry & neuroscience |
| 21333900 | The role of genetics in IBS. | Saito YA et al. | 2011 | Gastroenterology clinics of North America |
| 21687501 | Pharmacogenetics of antidepressants. | Crisafulli C et al. | 2011 | Frontiers in pharmacology |
| 21711518 | Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms. | Murphy TM et al. | 2011 | Behavioral and brain functions |
| 21728034 | Methamphetamine-associated psychosis. | Grant KM et al. | 2012 | Journal of neuroimmune pharmacology |
| 21741447 | Interaction between two HTR2A polymorphisms and gender is associated with treatment response in MDD. | Viikki M et al. | 2011 | Neuroscience letters |
| 21760883 | Genetic determinants of UV-susceptibility in non-melanoma skin cancer. | Welsh MM et al. | 2011 | PloS one |
| 21874579 | Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder. | Walitza S et al. | 2012 | Journal of neural transmission (Vienna, Austria |
| 22046326 | 'Smoking genes': a genetic association study. | Verde Z et al. | 2011 | PloS one |
| 22214315 | Isochromosome 13 in a patient with childhood-onset schizophrenia, ADHD, and motor tic disorder. | Graw SL et al. | 2012 | Molecular cytogenetics |
| 22615781 | Candidate gene-based association study of antipsychotic-induced movement disorders in long-stay psychiatric patients: a prospective study. | Bakker PR et al. | 2012 | PloS one |
| 22650965 | Paradox of schizophrenia genetics: is a paradigm shift occurring? | Doi N et al. | 2012 | Behavioral and brain functions |
| 22717018 | Escitalopram reduces attentional performance in anxious older adults with high-expression genetic variants at serotonin 2A and 1B receptors. | Lenze EJ et al. | 2013 | The international journal of neuropsychopharmacology |
| 22933845 | Polymorphisms of the serotonin transporter and receptor genes: susceptibility to substance abuse. | Herman AI et al. | 2012 | Substance abuse and rehabilitation |
| 23158458 | Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex. | Smith RM et al. | 2013 | Biological psychiatry |
| 23221997 | TPH1, MAOA, serotonin receptor 2A and 2C genes in citalopram response: possible effect in melancholic and psychotic depression. | Arias B et al. | 2013 | Neuropsychobiology |
| 23318131 | Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery. | Lebe M et al. | 2013 | Pain |
| 23429840 | Prepulse inhibition of startle response: recent advances in human studies of psychiatric disease. | Takahashi H et al. | 2011 | Clinical psychopharmacology and neuroscience |
| 23547754 | Genetics of serotonin receptors and depression: state of the art. | Fabbri C et al. | 2013 | Current drug targets |
| 23733030 | Pharmacogenetics in major depression: a comprehensive meta-analysis. | Niitsu T et al. | 2013 | Progress in neuro-psychopharmacology & biological psychiatry |
| 23872233 | The relationship between the presence of ADHD and certain candidate gene polymorphisms in a Turkish sample. | Pazvantoğlu O et al. | 2013 | Gene |
| 24021217 | Common selective serotonin reuptake inhibitor side effects in older adults associated with genetic polymorphisms in the serotonin transporter and receptors: data from a randomized controlled trial. | Garfield LD et al. | 2014 | The American journal of geriatric psychiatry |
| 24178752 | Association of the HTR2A gene with alcohol and heroin abuse. | Cao J et al. | 2014 | Human genetics |
| 24307977 | A pilot study evaluating genetic and environmental factors for postpartum depression. | El-Ibiary SY et al. | 2013 | Innovations in clinical neuroscience |
| 24355137 | The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and borderline personality disorder in female heroin-dependent Chinese subjects. | Yang M et al. | 2014 | Progress in neuro-psychopharmacology & biological psychiatry |
| 24533444 | Female sexual dysfunction in patients with major depressive disorder (MDD) treated with selective serotonin reuptake inhibitor (SSRI) and its association with serotonin 2A-1438 G/A single nucleotide polymorphisms. | Masiran R et al. | 2014 | The journal of sexual medicine |
| 24643765 | 5-HTTLPR, HTR1A, and HTR2A cumulative genetic score interacts with mood reactivity to predict mood-congruent gaze bias. | Disner SG et al. | 2014 | Cognitive, affective & behavioral neuroscience |
| 24881125 | From pharmacogenetics to pharmacogenomics: the way toward the personalization of antidepressant treatment. | Fabbri C et al. | 2014 | Canadian journal of psychiatry. Revue canadienne de psychiatrie |
| 24885933 | Towards the clinical implementation of pharmacogenetics in bipolar disorder. | Salloum NC et al. | 2014 | BMC medicine |
| 24944790 | Screening for 392 polymorphisms in 141 pharmacogenes. | Kim JY et al. | 2014 | Biomedical reports |
| 25017045 | The neurobiological link between OCD and ADHD. | Brem S et al. | 2014 | Attention deficit and hyperactivity disorders |
| 25041420 | Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain. | Marinova Z et al. | 2015 | Neuropathology and applied neurobiology |
| 25108775 | Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis. | Lin JY et al. | 2014 | Journal of affective disorders |
| 25174699 | Serotonin receptor gene (5HT-2A) polymorphism is associated with provoked vestibulodynia and comorbid symptoms of pain. | Heddini U et al. | 2014 | The journal of sexual medicine |
| 25264393 | Association between serotonin cumulative genetic score and the Behavioral Approach System (BAS): Moderation by early life environment. | Pearson R et al. | 2014 | Personality and individual differences |
| 25459290 | Single 5HTR2A-1438 A/G nucleotide polymorphism affects performance in a metacontrast masking task: implications for vulnerability testing and neuromodulation of pyramidal cells. | Maksimov M et al. | 2015 | Neuroscience letters |
| 25658328 | Polymorphism in the serotonin receptor 2a (HTR2A) gene as possible predisposal factor for aggressive traits. | Banlaki Z et al. | 2015 | PloS one |
| 26149086 | DNA Methylation Analysis of HTR2A Regulatory Region in Leukocytes of Autistic Subjects. | Hranilovic D et al. | 2016 | Autism research |
| 26261165 | Association of serotonin transporter (SLC6A4) and receptor (5HTR1A, 5HTR2A) polymorphisms with response to treatment with escitalopram in patients with major depressive disorder: A preliminary study. | Basu A et al. | 2015 | The Indian journal of medical research |
| 26322220 | A comprehensive meta-analysis of common genetic variants in autism spectrum conditions. | Warrier V et al. | 2015 | Molecular autism |
| 26543368 | Epidemiological support for genetic variability at hypothalamic-pituitary-adrenal axis and serotonergic system as risk factors for major depression. | Ching-López A et al. | 2015 | Neuropsychiatric disease and treatment |
| 26613086 | Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis. | Prieto-Pérez R et al. | 2015 | Journal of immunology research |
| 26616111 | Disorder-specific genetic factors in obsessive-compulsive disorder: A comprehensive meta-analysis. | Taylor S et al. | 2016 | American journal of medical genetics. Part B, Neuropsychiatric genetics |
| 26858594 | Oxytocin and Vasopressin Receptor Gene Polymorphisms: Role in Social and Psychiatric Traits. | Aspé-Sánchez M et al. | 2015 | Frontiers in neuroscience |
| 26989097 | Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders. | Coleman JR et al. | 2016 | The British journal of psychiatry |
| 27091189 | Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway. | Cocchi E et al. | 2016 | BMC psychiatry |
| 27126880 | Serotonin as a New Therapeutic Target for Diabetes Mellitus and Obesity. | Oh CM et al. | 2016 | Diabetes & metabolism journal |
| 27193909 | Gender Interacts with Opioid Receptor Polymorphism A118G and Serotonin Receptor Polymorphism -1438 A/G on Speed-Dating Success. | Wu K et al. | 2016 | Human nature (Hawthorne, N.Y.) |
| 27247849 | Genetic variation and cognitive dysfunction in opioid-treated patients with cancer. | Kurita GP et al. | 2016 | Brain and behavior |
| 27375535 | Molecular Signatures of Natural Selection for Polymorphic Genes of the Human Dopaminergic and Serotonergic Systems: A Review. | Taub DR et al. | 2016 | Frontiers in psychology |
| 27445478 | 5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients. | Dong ZQ et al. | 2016 | Neuropsychiatric disease and treatment |
| 27445670 | 5-HT2A Gene Variants Moderate the Association between PTSD and Reduced Default Mode Network Connectivity. | Miller MW et al. | 2016 | Frontiers in neuroscience |
| 27489378 | Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population. | Yücel Y et al. | 2016 | Clinical psychopharmacology and neuroscience |
| 27521242 | TPH-2 Polymorphisms Interact with Early Life Stress to Influence Response to Treatment with Antidepressant Drugs. | Xu Z et al. | 2016 | The international journal of neuropsychopharmacology |
| 27529241 | The Risk of Congenital Heart Anomalies Following Prenatal Exposure to Serotonin Reuptake Inhibitors-Is Pharmacogenetics the Key? | Daud AN et al. | 2016 | International journal of molecular sciences |
| 27598719 | Meta-analysis of polymorphism rs6311 and rs6313 in the 5-HT<sub>2A</sub>R gene and schizophrenia. | Sun L et al. | 2017 | Nordic journal of psychiatry |
| 27721799 | Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions. | Mirkovic B et al. | 2016 | Frontiers in psychiatry |
| 27756686 | Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population. | Zhang R et al. | 2016 | Neuroscience letters |
| 27757066 | Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations. | Eum S et al. | 2016 | Dialogues in clinical neuroscience |
| 27895608 | Genetic Consideration of Schizotypal Traits: A Review. | Walter EE et al. | 2016 | Frontiers in psychology |
| 27912162 | Serotonin 2A receptor (5-HT2A) gene promoter variant interacts with chronic perceived stress to modulate resting parasympathetic activity in humans. | Chang CC et al. | 2017 | Psychoneuroendocrinology |
| 28103253 | Polymorphisms in HTR2A and DRD4 Predispose to Smoking and Smoking Quantity. | Pérez-Rubio G et al. | 2017 | PloS one |
| 28470827 | Pharmacogenomics and Efficacy of Risperidone Long-Term Treatment in Thai Autistic Children and Adolescents. | Nuntamool N et al. | 2017 | Basic & clinical pharmacology & toxicology |
| 28576508 | A review of the role of serotonin system genes in obsessive-compulsive disorder. | Sinopoli VM et al. | 2017 | Neuroscience and biobehavioral reviews |
| 28951738 | Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders. | Grzesiak M et al. | 2017 | Gastroenterology research and practice |
| 29120849 | Genetic analysis of impulsive personality traits: Examination of a priori candidates and genome-wide variation. | Gray JC et al. | 2018 | Psychiatry research |
| 29193749 | Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years. | Borobia AM et al. | 2018 | Clinical and translational science |
| 29311795 | Neural and Genetic Correlates of the Social Sharing of Happiness. | Matsunaga M et al. | 2017 | Frontiers in neuroscience |
| 29331882 | Association analysis of SLC6A4 and HTR2A genes with obsessive-compulsive disorder: Influence of the STin2 polymorphism. | Gomes CKF et al. | 2018 | Comprehensive psychiatry |
| 29358097 | The effect of 5-HTTLPR and a serotonergic multi-marker score on amygdala, prefrontal and anterior cingulate cortex reactivity and habituation in a large, healthy fMRI cohort. | Piel JH et al. | 2018 | European neuropsychopharmacology |
| 29526601 | Association between serotonin 2A receptor genetic variations, stressful life events and suicide. | Ghasemi A et al. | 2018 | Gene |
| 29661255 | Serotonergic gene polymorphisms (5-HTTLPR, 5HTR1A, 5HTR2A), and population differences in aggression: traditional (Hadza and Datoga) and industrial (Russians) populations compared. | Butovskaya ML et al. | 2018 | Journal of physiological anthropology |
| 29785111 | Association of serotonin receptor 2a haplotypes with obsessive-compulsive disorder and its treatment response in Iranian patients: a genetic and pharmacogenetic study. | Sina M et al. | 2018 | Neuropsychiatric disease and treatment |
| 30093869 | Biological Predictors of Clozapine Response: A Systematic Review. | Samanaite R et al. | 2018 | Frontiers in psychiatry |
| 30178121 | Neuroplasticity, Neurotransmission and Brain-Related Genes in Major Depression and Bipolar Disorder: Focus on Treatment Outcomes in an Asiatic Sample. | Calabrò M et al. | 2018 | Advances in therapy |
| 30219683 | Association of HTR2A-1438G/A Genetic Polymorphism With Smoking and Chronic Obstructive Pulmonary Disease. | Verde Z et al. | 2019 | Archivos de bronconeumologia |
| 30375534 | Assessment of Pain Sensitivity in Patients With Chronic Low Back Pain and Association With HTR2A Gene Polymorphism. | Yildiz SH et al. | 2017 | Archives of rheumatology |
| 30389402 | An association study of dopaminergic (DRD2) and serotoninergic (5-HT2) gene polymorphism and schizophrenia in a North Indian population. | Kaur G et al. | 2019 | Asian journal of psychiatry |
| 30554102 | Genetic variability in the serotoninergic system and age of onset in anorexia nervosa and obsessive-compulsive disorder. | Plana MT et al. | 2019 | Psychiatry research |
| 30607769 | Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population. | Luo C et al. | 2019 | Neuroscience bulletin |
| 30789538 | Association of polymorphisms in HTR2A, TPH1, and TPH2 genes with attempted suicide in rural China. | Pan YF et al. | 2019 | Psychiatric genetics |
| 30923939 | Association of TPH1 and serotonin transporter genotypes with treatment response for suicidal ideation: a preliminary study. | Nielsen DA et al. | 2020 | European archives of psychiatry and clinical neuroscience |
| 30973927 | Single nucleotide polymorphism analysis in interstitial cystitis/painful bladder syndrome. | Cassão VD et al. | 2019 | PloS one |
| 31061854 | Data on genotype frequency for SNPs associated to age of smoking onset and successful smoking cessation treatment. | Pérez-Rubio G et al. | 2019 | Data in brief |
| 31111219 | Genetic endophenotypes for insomnia of major depressive disorder and treatment-induced insomnia. | Badamasi IM et al. | 2019 | Journal of neural transmission (Vienna, Austria |
| 31129315 | Systematic Review and Meta-Analysis of Genetic Risk of Developing Chronic Postsurgical Pain. | Chidambaran V et al. | 2020 | The journal of pain |
| 31148856 | Investigation of Immunovascular Polymorphisms and Intersections in Psoriasis. | Urganci BE et al. | 2019 | Indian journal of dermatology |
| 31199591 | Genetic association analysis of 5-HTR2A gene variants in eating disorders in a Mexican population. | Genis-Mendoza AD et al. | 2019 | Brain and behavior |
| 31228794 | A preliminary association study between serotonin transporter (5-HTTLPR), receptor polymorphisms (5-HTR1A, 5-HTR2A) and depression symptom-clusters in a north Indian population suffering from Major Depressive Disorder (MDD). | Basu A et al. | 2019 | Asian journal of psychiatry |
| 31258491 | Childhood Adversity Moderates the Effects of <i>HTR2A</i> Epigenetic Regulatory Polymorphisms on Rumination. | Eszlari N et al. | 2019 | Frontiers in psychiatry |
| 31721892 | Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial. | Brunoni AR et al. | 2020 | Revista brasileira de psiquiatria (Sao Paulo, Brazil |
| 32265436 | Machine learning classification of ADHD and HC by multimodal serotonergic data. | Kautzky A et al. | 2020 | Translational psychiatry |
| 32553368 | The rs6311 of serotonin receptor 2A (5-HT2A) gene is associated with alexithymia and mental health. | Li X et al. | 2020 | Journal of affective disorders |
| 32576619 | Effects of <i>TPH2</i> gene variation and childhood trauma on the clinical and circuit-level phenotype of functional movement disorders. | Spagnolo PA et al. | 2020 | Journal of neurology, neurosurgery, and psychiatry |
| 32697408 | Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels. | Spies M et al. | 2020 | Human brain mapping |
| 32819202 | Association between genetic polymorphism and antidepressants in major depression: a network meta-analysis. | Du D et al. | 2020 | Pharmacogenomics |
| 32992097 | Association of the genetic polymorphisms of metabolizing enzymes, transporters, target receptors and their interactions with treatment response to olanzapine in chinese han schizophrenia patients. | Yan P et al. | 2020 | Psychiatry research |
| 33171011 | The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients. | Sachau J et al. | 2021 | European journal of pain (London, England) |
| 33324248 | Genetic Determinants of Gating Functions: Do We Get Closer to Understanding Schizophrenia Etiopathogenesis? | Rovný R et al. | 2020 | Frontiers in psychiatry |
| 33567384 | Associations and interactions of the serotonin receptor genes 5-HT1A, 5-HT2A, and childhood trauma with alexithymia in two independent general-population samples. | Terock J et al. | 2021 | Psychiatry research |
| 33644845 | Association between autism spectrum disorder and polymorphisms in genes encoding serotine and dopamine receptors. | Liu J et al. | 2021 | Metabolic brain disease |
Help
The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.
Genome context:
Select flank length:
Genomic regions, transcripts, and products
Top▲
Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.