dbSNP Short Genetic Variations
Welcome to the Reference SNP (rs) Report
All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.
Reference SNP (rs) Report
This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.
rs5743708
Current Build 155
Released April 9, 2021
- Organism
- Homo sapiens
- Position
-
chr4:153705165 (GRCh38.p13) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
- Alleles
- G>A
- Variation Type
- SNV Single Nucleotide Variation
- Frequency
-
A=0.015093 (3995/264690, TOPMED)A=0.017426 (4375/251060, GnomAD_exome)A=0.018441 (2584/140124, GnomAD) (+ 18 more)
- Clinical Significance
- Reported in ClinVar
- Gene : Consequence
- TLR2 : Missense Variant
- Publications
- 107 citations
- Genomic View
- See rs on genome
ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|
| Total | Global | 68908 | G=0.97373 | A=0.02627 |
| European | Sub | 56386 | G=0.97107 | A=0.02893 |
| African | Sub | 3574 | G=0.9975 | A=0.0025 |
| African Others | Sub | 122 | G=1.000 | A=0.000 |
| African American | Sub | 3452 | G=0.9974 | A=0.0026 |
| Asian | Sub | 168 | G=1.000 | A=0.000 |
| East Asian | Sub | 112 | G=1.000 | A=0.000 |
| Other Asian | Sub | 56 | G=1.00 | A=0.00 |
| Latin American 1 | Sub | 500 | G=0.996 | A=0.004 |
| Latin American 2 | Sub | 648 | G=0.992 | A=0.008 |
| South Asian | Sub | 98 | G=1.00 | A=0.00 |
| Other | Sub | 7534 | G=0.9784 | A=0.0216 |
Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").
Download| Study | Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| TopMed | Global | Study-wide | 264690 | G=0.984907 | A=0.015093 |
| gnomAD - Exomes | Global | Study-wide | 251060 | G=0.982574 | A=0.017426 |
| gnomAD - Exomes | European | Sub | 135052 | G=0.971404 | A=0.028596 |
| gnomAD - Exomes | Asian | Sub | 49010 | G=0.99839 | A=0.00161 |
| gnomAD - Exomes | American | Sub | 34576 | G=0.99439 | A=0.00561 |
| gnomAD - Exomes | African | Sub | 16234 | G=0.99612 | A=0.00388 |
| gnomAD - Exomes | Ashkenazi Jewish | Sub | 10060 | G=0.99254 | A=0.00746 |
| gnomAD - Exomes | Other | Sub | 6128 | G=0.9834 | A=0.0166 |
| gnomAD - Genomes | Global | Study-wide | 140124 | G=0.981559 | A=0.018441 |
| gnomAD - Genomes | European | Sub | 75868 | G=0.97055 | A=0.02945 |
| gnomAD - Genomes | African | Sub | 42000 | G=0.99567 | A=0.00433 |
| gnomAD - Genomes | American | Sub | 13650 | G=0.99158 | A=0.00842 |
| gnomAD - Genomes | Ashkenazi Jewish | Sub | 3324 | G=0.9925 | A=0.0075 |
| gnomAD - Genomes | East Asian | Sub | 3128 | G=1.0000 | A=0.0000 |
| gnomAD - Genomes | Other | Sub | 2154 | G=0.9870 | A=0.0130 |
| ExAC | Global | Study-wide | 121066 | G=0.982728 | A=0.017272 |
| ExAC | Europe | Sub | 73048 | G=0.97354 | A=0.02646 |
| ExAC | Asian | Sub | 25162 | G=0.99833 | A=0.00167 |
| ExAC | American | Sub | 11576 | G=0.99499 | A=0.00501 |
| ExAC | African | Sub | 10372 | G=0.99605 | A=0.00395 |
| ExAC | Other | Sub | 908 | G=0.981 | A=0.019 |
| Allele Frequency Aggregator | Total | Global | 68908 | G=0.97373 | A=0.02627 |
| Allele Frequency Aggregator | European | Sub | 56386 | G=0.97107 | A=0.02893 |
| Allele Frequency Aggregator | Other | Sub | 7534 | G=0.9784 | A=0.0216 |
| Allele Frequency Aggregator | African | Sub | 3574 | G=0.9975 | A=0.0025 |
| Allele Frequency Aggregator | Latin American 2 | Sub | 648 | G=0.992 | A=0.008 |
| Allele Frequency Aggregator | Latin American 1 | Sub | 500 | G=0.996 | A=0.004 |
| Allele Frequency Aggregator | Asian | Sub | 168 | G=1.000 | A=0.000 |
| Allele Frequency Aggregator | South Asian | Sub | 98 | G=1.00 | A=0.00 |
| 8.3KJPN | JAPANESE | Study-wide | 16760 | G=0.99994 | A=0.00006 |
| GO Exome Sequencing Project | Global | Study-wide | 13006 | G=0.97778 | A=0.02222 |
| GO Exome Sequencing Project | European American | Sub | 8600 | G=0.9691 | A=0.0309 |
| GO Exome Sequencing Project | African American | Sub | 4406 | G=0.9948 | A=0.0052 |
| 1000Genomes | Global | Study-wide | 5008 | G=0.9932 | A=0.0068 |
| 1000Genomes | African | Sub | 1322 | G=1.0000 | A=0.0000 |
| 1000Genomes | East Asian | Sub | 1008 | G=0.9990 | A=0.0010 |
| 1000Genomes | Europe | Sub | 1006 | G=0.9761 | A=0.0239 |
| 1000Genomes | South Asian | Sub | 978 | G=0.999 | A=0.001 |
| 1000Genomes | American | Sub | 694 | G=0.988 | A=0.012 |
| Genetic variation in the Estonian population | Estonian | Study-wide | 4480 | G=0.9525 | A=0.0475 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | G=0.9699 | A=0.0301 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | G=0.9641 | A=0.0359 |
| Genome of the Netherlands Release 5 | Genome of the Netherlands | Study-wide | 998 | G=0.949 | A=0.051 |
| Northern Sweden | ACPOP | Study-wide | 600 | G=0.988 | A=0.012 |
| Medical Genome Project healthy controls from Spanish population | Spanish controls | Study-wide | 534 | G=0.996 | A=0.004 |
| HapMap | Global | Study-wide | 316 | G=0.981 | A=0.019 |
| HapMap | African | Sub | 116 | G=1.000 | A=0.000 |
| HapMap | American | Sub | 116 | G=0.948 | A=0.052 |
| HapMap | Asian | Sub | 84 | G=1.00 | A=0.00 |
| FINRISK | Finnish from FINRISK project | Study-wide | 304 | G=0.970 | A=0.030 |
| Ancient Sardinia genome-wide 1240k capture data generation and analysis | Global | Study-wide | 62 | G=0.90 | A=0.10 |
| SGDP_PRJ | Global | Study-wide | 8 | G=0.5 | A=0.5 |
| Siberian | Global | Study-wide | 2 | G=0.5 | A=0.5 |
Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.
| Sequence name | Change |
|---|---|
| GRCh38.p13 chr 4 | NC_000004.12:g.153705165G>A |
| GRCh37.p13 chr 4 | NC_000004.11:g.154626317G>A |
| TLR2 RefSeqGene | NG_016229.1:g.25877G>A |
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| TLR2 transcript variant 6 | NM_001318793.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305722.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 7 | NM_001318795.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305724.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 5 | NM_001318791.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305720.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 1 | NM_001318787.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305716.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 4 | NM_001318790.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305719.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 3 | NM_003264.5:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_003255.2:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 2 | NM_001318789.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305718.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant 8 | NM_001318796.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 precursor | NP_001305725.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X1 | XM_017008573.1:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_016864062.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X2 | XM_017008574.1:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_016864063.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X3 | XM_017008575.1:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_016864064.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X4 | XM_017008576.1:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_016864065.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X5 | XM_011532215.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_011530517.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
| TLR2 transcript variant X6 | XM_011532216.2:c.2258G>A | R [CGG] > Q [CAG] | Coding Sequence Variant |
| toll-like receptor 2 isoform X1 | XP_011530518.1:p.Arg753Gln | R (Arg) > Q (Gln) | Missense Variant |
Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.
| ClinVar Accession | Disease Names | Clinical Significance |
|---|---|---|
| RCV000033853.4 | Mycobacterium tuberculosis, susceptibility to | Risk-Factor |
Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".
| Placement | G= | A |
|---|---|---|
| GRCh38.p13 chr 4 | NC_000004.12:g.153705165= | NC_000004.12:g.153705165G>A |
| GRCh37.p13 chr 4 | NC_000004.11:g.154626317= | NC_000004.11:g.154626317G>A |
| TLR2 RefSeqGene | NG_016229.1:g.25877= | NG_016229.1:g.25877G>A |
| TLR2 transcript variant 3 | NM_003264.5:c.2258= | NM_003264.5:c.2258G>A |
| TLR2 transcript variant 3 | NM_003264.4:c.2258= | NM_003264.4:c.2258G>A |
| TLR2 transcript | NM_003264.3:c.2258= | NM_003264.3:c.2258G>A |
| TLR2 transcript variant 1 | NM_001318787.2:c.2258= | NM_001318787.2:c.2258G>A |
| TLR2 transcript variant 1 | NM_001318787.1:c.2258= | NM_001318787.1:c.2258G>A |
| TLR2 transcript variant 2 | NM_001318789.2:c.2258= | NM_001318789.2:c.2258G>A |
| TLR2 transcript variant 2 | NM_001318789.1:c.2258= | NM_001318789.1:c.2258G>A |
| TLR2 transcript variant 4 | NM_001318790.2:c.2258= | NM_001318790.2:c.2258G>A |
| TLR2 transcript variant 4 | NM_001318790.1:c.2258= | NM_001318790.1:c.2258G>A |
| TLR2 transcript variant 5 | NM_001318791.2:c.2258= | NM_001318791.2:c.2258G>A |
| TLR2 transcript variant 5 | NM_001318791.1:c.2258= | NM_001318791.1:c.2258G>A |
| TLR2 transcript variant 6 | NM_001318793.2:c.2258= | NM_001318793.2:c.2258G>A |
| TLR2 transcript variant 6 | NM_001318793.1:c.2258= | NM_001318793.1:c.2258G>A |
| TLR2 transcript variant 7 | NM_001318795.2:c.2258= | NM_001318795.2:c.2258G>A |
| TLR2 transcript variant 7 | NM_001318795.1:c.2258= | NM_001318795.1:c.2258G>A |
| TLR2 transcript variant 8 | NM_001318796.2:c.2258= | NM_001318796.2:c.2258G>A |
| TLR2 transcript variant 8 | NM_001318796.1:c.2258= | NM_001318796.1:c.2258G>A |
| TLR2 transcript variant X5 | XM_011532215.2:c.2258= | XM_011532215.2:c.2258G>A |
| TLR2 transcript variant X6 | XM_011532216.2:c.2258= | XM_011532216.2:c.2258G>A |
| TLR2 transcript variant X4 | XM_017008576.1:c.2258= | XM_017008576.1:c.2258G>A |
| TLR2 transcript variant X1 | XM_017008573.1:c.2258= | XM_017008573.1:c.2258G>A |
| TLR2 transcript variant X3 | XM_017008575.1:c.2258= | XM_017008575.1:c.2258G>A |
| TLR2 transcript variant X2 | XM_017008574.1:c.2258= | XM_017008574.1:c.2258G>A |
| toll-like receptor 2 precursor | NP_003255.2:p.Arg753= | NP_003255.2:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305716.1:p.Arg753= | NP_001305716.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305718.1:p.Arg753= | NP_001305718.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305719.1:p.Arg753= | NP_001305719.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305720.1:p.Arg753= | NP_001305720.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305722.1:p.Arg753= | NP_001305722.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305724.1:p.Arg753= | NP_001305724.1:p.Arg753Gln |
| toll-like receptor 2 precursor | NP_001305725.1:p.Arg753= | NP_001305725.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_011530517.1:p.Arg753= | XP_011530517.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_011530518.1:p.Arg753= | XP_011530518.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_016864065.1:p.Arg753= | XP_016864065.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_016864062.1:p.Arg753= | XP_016864062.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_016864064.1:p.Arg753= | XP_016864064.1:p.Arg753Gln |
| toll-like receptor 2 isoform X1 | XP_016864063.1:p.Arg753= | XP_016864063.1:p.Arg753Gln |
Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.
| No | Submitter | Submission ID | Date (Build) |
|---|---|---|---|
| 1 | IIPGA-WEISS-MARTINEZ | ss7987693 | Apr 21, 2003 (114) |
| 2 | SNP500CANCER | ss48297135 | Mar 13, 2006 (126) |
| 3 | PERLEGEN | ss68915072 | May 17, 2007 (127) |
| 4 | BCMHGSC_JDW | ss92834584 | Mar 24, 2008 (129) |
| 5 | SEATTLESEQ | ss159708587 | Dec 01, 2009 (131) |
| 6 | ILLUMINA | ss160744833 | Dec 01, 2009 (131) |
| 7 | 1000GENOMES | ss232662281 | Jul 14, 2010 (132) |
| 8 | NHLBI-ESP | ss342173302 | May 09, 2011 (134) |
| 9 | ILLUMINA | ss482164470 | Sep 08, 2015 (146) |
| 10 | 1000GENOMES | ss490896112 | May 04, 2012 (137) |
| 11 | EXOME_CHIP | ss491361656 | May 04, 2012 (137) |
| 12 | CLINSEQ_SNP | ss491861024 | May 04, 2012 (137) |
| 13 | ILLUMINA | ss783516337 | Sep 08, 2015 (146) |
| 14 | OMIM-CURATED-RECORDS | ss836177066 | Oct 18, 2013 (136) |
| 15 | EVA-GONL | ss980852680 | Aug 21, 2014 (142) |
| 16 | 1000GENOMES | ss1312477594 | Aug 21, 2014 (142) |
| 17 | EVA_FINRISK | ss1584036623 | Apr 01, 2015 (144) |
| 18 | EVA_DECODE | ss1590366060 | Apr 01, 2015 (144) |
| 19 | EVA_UK10K_ALSPAC | ss1611521201 | Apr 01, 2015 (144) |
| 20 | EVA_UK10K_TWINSUK | ss1654515234 | Apr 01, 2015 (144) |
| 21 | EVA_EXAC | ss1687668038 | Apr 01, 2015 (144) |
| 22 | EVA_MGP | ss1711074058 | Apr 01, 2015 (144) |
| 23 | ILLUMINA | ss1917785600 | Feb 12, 2016 (147) |
| 24 | ILLUMINA | ss1946130340 | Feb 12, 2016 (147) |
| 25 | ILLUMINA | ss1958731117 | Feb 12, 2016 (147) |
| 26 | JJLAB | ss2022631477 | Sep 14, 2016 (149) |
| 27 | ILLUMINA | ss2094817089 | Dec 20, 2016 (150) |
| 28 | USC_VALOUEV | ss2150764458 | Dec 20, 2016 (150) |
| 29 | HUMAN_LONGEVITY | ss2268506308 | Dec 20, 2016 (150) |
| 30 | TOPMED | ss2436443325 | Dec 20, 2016 (150) |
| 31 | ILLUMINA | ss2634195830 | Nov 08, 2017 (151) |
| 32 | GNOMAD | ss2734782824 | Nov 08, 2017 (151) |
| 33 | GNOMAD | ss2747317021 | Nov 08, 2017 (151) |
| 34 | GNOMAD | ss2817168157 | Nov 08, 2017 (151) |
| 35 | AFFY | ss2985306679 | Nov 08, 2017 (151) |
| 36 | SWEGEN | ss2995822688 | Nov 08, 2017 (151) |
| 37 | ILLUMINA | ss3022427798 | Nov 08, 2017 (151) |
| 38 | CSHL | ss3346036726 | Nov 08, 2017 (151) |
| 39 | TOPMED | ss3447151461 | Nov 08, 2017 (151) |
| 40 | ILLUMINA | ss3625858488 | Oct 12, 2018 (152) |
| 41 | ILLUMINA | ss3634976141 | Oct 12, 2018 (152) |
| 42 | ILLUMINA | ss3636683326 | Oct 12, 2018 (152) |
| 43 | ILLUMINA | ss3640683434 | Oct 12, 2018 (152) |
| 44 | ILLUMINA | ss3644863183 | Oct 12, 2018 (152) |
| 45 | ILLUMINA | ss3652918392 | Oct 12, 2018 (152) |
| 46 | ILLUMINA | ss3654078731 | Oct 12, 2018 (152) |
| 47 | EGCUT_WGS | ss3663732349 | Jul 13, 2019 (153) |
| 48 | EVA_DECODE | ss3713381358 | Jul 13, 2019 (153) |
| 49 | ACPOP | ss3731750188 | Jul 13, 2019 (153) |
| 50 | ILLUMINA | ss3744530815 | Jul 13, 2019 (153) |
| 51 | ILLUMINA | ss3745276368 | Jul 13, 2019 (153) |
| 52 | EVA | ss3762611013 | Jul 13, 2019 (153) |
| 53 | EVA | ss3824052552 | Apr 26, 2020 (154) |
| 54 | EVA | ss3825665743 | Apr 26, 2020 (154) |
| 55 | EVA | ss3828889750 | Apr 26, 2020 (154) |
| 56 | SGDP_PRJ | ss3860402316 | Apr 26, 2020 (154) |
| 57 | EVA | ss3985103895 | Apr 26, 2021 (155) |
| 58 | EVA | ss3986294420 | Apr 26, 2021 (155) |
| 59 | TOPMED | ss4637824812 | Apr 26, 2021 (155) |
| 60 | TOMMO_GENOMICS | ss5168757325 | Apr 26, 2021 (155) |
| 61 | 1000Genomes | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 62 | The Avon Longitudinal Study of Parents and Children | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 63 | Genetic variation in the Estonian population | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 64 | ExAC | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 65 | FINRISK | NC_000004.11 - 154626317 | Apr 26, 2020 (154) |
| 66 | gnomAD - Genomes | NC_000004.12 - 153705165 | Apr 26, 2021 (155) |
| 67 | gnomAD - Exomes | NC_000004.11 - 154626317 | Jul 13, 2019 (153) |
| 68 | GO Exome Sequencing Project | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 69 | Genome of the Netherlands Release 5 | NC_000004.11 - 154626317 | Apr 26, 2020 (154) |
| 70 | HapMap | NC_000004.12 - 153705165 | Apr 26, 2020 (154) |
| 71 | Medical Genome Project healthy controls from Spanish population | NC_000004.11 - 154626317 | Apr 26, 2020 (154) |
| 72 | Northern Sweden | NC_000004.11 - 154626317 | Jul 13, 2019 (153) |
| 73 | Ancient Sardinia genome-wide 1240k capture data generation and analysis | NC_000004.11 - 154626317 | Apr 26, 2021 (155) |
| 74 | SGDP_PRJ | NC_000004.11 - 154626317 | Apr 26, 2020 (154) |
| 75 | Siberian | NC_000004.11 - 154626317 | Apr 26, 2020 (154) |
| 76 | 8.3KJPN | NC_000004.11 - 154626317 | Apr 26, 2021 (155) |
| 77 | TopMed | NC_000004.12 - 153705165 | Apr 26, 2021 (155) |
| 78 | UK 10K study - Twins | NC_000004.11 - 154626317 | Oct 12, 2018 (152) |
| 79 | ALFA | NC_000004.12 - 153705165 | Apr 26, 2021 (155) |
| 80 | ClinVar | RCV000033853.4 | Oct 12, 2018 (152) |
History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).
| Submission IDs | Observation SPDI | Canonical SPDI | Source RSIDs |
|---|---|---|---|
| ss92834584, ss491861024, ss1590366060 | NC_000004.10:154845766:G:A | NC_000004.12:153705164:G:A | (self) |
| 23977632, 13335239, 9470597, 7647480, 33084, 3894688, 510738, 5906166, 189818, 5035053, 329822, 12419296, 3280812, 26726632, 13335239, ss232662281, ss342173302, ss482164470, ss490896112, ss491361656, ss783516337, ss980852680, ss1312477594, ss1584036623, ss1611521201, ss1654515234, ss1687668038, ss1711074058, ss1917785600, ss1946130340, ss1958731117, ss2022631477, ss2094817089, ss2150764458, ss2436443325, ss2634195830, ss2734782824, ss2747317021, ss2817168157, ss2985306679, ss2995822688, ss3022427798, ss3346036726, ss3625858488, ss3634976141, ss3636683326, ss3640683434, ss3644863183, ss3652918392, ss3654078731, ss3663732349, ss3731750188, ss3744530815, ss3745276368, ss3762611013, ss3824052552, ss3825665743, ss3828889750, ss3860402316, ss3985103895, ss3986294420, ss5168757325 | NC_000004.11:154626316:G:A | NC_000004.12:153705164:G:A | (self) |
| RCV000033853.4, 169852108, 2737853, 297074597, 475202368, 7785968456, ss836177066, ss2268506308, ss3447151461, ss3713381358, ss4637824812 | NC_000004.12:153705164:G:A | NC_000004.12:153705164:G:A | (self) |
| ss7987693, ss48297135, ss68915072, ss159708587, ss160744833 | NT_016354.19:79174037:G:A | NC_000004.12:153705164:G:A | (self) |
Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.
| PMID | Title | Author | Year | Journal |
|---|---|---|---|---|
| 14979495 | The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease. | Ogus AC et al. | 2004 | The European respiratory journal |
| 16081826 | Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease. | Schröder NW et al. | 2005 | Journal of immunology (Baltimore, Md. |
| 16608528 | Genetic polymorphisms and susceptibility to lung disease. | Lee PL et al. | 2006 | Journal of negative results in biomedicine |
| 16846490 | Lemierre's syndrome and genetic polymorphisms: a case report. | Constantin JM et al. | 2006 | BMC infectious diseases |
| 17565608 | Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis. | Veltkamp M et al. | 2007 | Clinical and experimental immunology |
| 17667860 | Toll-like receptor 2 polymorphism is associated with preterm birth. | Krediet TG et al. | 2007 | Pediatric research |
| 18396467 | Genetic variation and haplotype structures of innate immunity genes in eastern India. | Bairagya BB et al. | 2008 | Infection, genetics and evolution |
| 18975326 | Toll-like receptor 2 variants are associated with acute reactive arthritis. | Tsui FW et al. | 2008 | Arthritis and rheumatism |
| 19029192 | A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma. | Purdue MP et al. | 2009 | Carcinogenesis |
| 19134200 | No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis. | Jaen O et al. | 2009 | Arthritis research & therapy |
| 19543401 | Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. | Hawn TR et al. | 2009 | PloS one |
| 20016852 | Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women. | Hawn TR et al. | 2009 | PloS one |
| 20196868 | Polymorphisms in IL-1beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis. | Motsinger-Reif AA et al. | 2010 | BMC medical genetics |
| 20445564 | Single nucleotide polymorphisms in toll-like receptor 6 are associated with altered lipopeptide- and mycobacteria-induced interleukin-6 secretion. | Shey MS et al. | 2010 | Genes and immunity |
| 20463618 | Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. | Abu-Maziad A et al. | 2010 | Pediatric research |
| 20577092 | Genetic variation of innate immune genes in HIV-infected african patients with or without oropharyngeal candidiasis. | Plantinga TS et al. | 2010 | Journal of acquired immune deficiency syndromes (1999) |
| 20595247 | Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients. | Enevold C et al. | 2010 | Multiple sclerosis (Houndmills, Basingstoke, England) |
| 20646321 | Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk. | Ashton KA et al. | 2010 | BMC cancer |
| 20818961 | Inflammatory mediators gene polymorphisms in preeclampsia. | Franchim CS et al. | 2011 | Hypertension in pregnancy |
| 21159925 | Toll-like receptor 4 gene (TLR4), but not TLR2, polymorphisms modify the risk of tonsillar disease due to Streptococcus pyogenes and Haemophilus influenzae. | Liadaki K et al. | 2011 | Clinical and vaccine immunology |
| 21179534 | Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome. | Coenen MJ et al. | 2010 | PloS one |
| 21219635 | Variants in the Toll-interacting protein gene are associated with susceptibility to sepsis in the Chinese Han population. | Song Z et al. | 2011 | Critical care (London, England) |
| 21298446 | Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study. | Bielinski SJ et al. | 2011 | Human genetics |
| 21356257 | Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis. | Nischalke HD et al. | 2011 | Journal of hepatology |
| 21466684 | Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients. | Koch A et al. | 2011 | Critical care (London, England) |
| 21500195 | The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C. | Nischalke HD et al. | 2012 | International journal of cancer |
| 21792899 | Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. | Slattery ML et al. | 2012 | International journal of cancer |
| 21852947 | Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. | Randhawa AK et al. | 2011 | PLoS pathogens |
| 21920464 | Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer. | Eyking A et al. | 2011 | Gastroenterology |
| 21931695 | Association of inherited variation in Toll-like receptor genes with malignant melanoma susceptibility and survival. | Gast A et al. | 2011 | PloS one |
| 22022564 | Nasopharyngeal bacterial colonization and gene polymorphisms of mannose-binding lectin and toll-like receptors 2 and 4 in infants. | Vuononvirta J et al. | 2011 | PloS one |
| 22128242 | The role of toll-like receptor variants in acute anterior uveitis. | Pratap DS et al. | 2011 | Molecular vision |
| 22301633 | Toll-like receptor 1 polymorphisms increase susceptibility to candidemia. | Plantinga TS et al. | 2012 | The Journal of infectious diseases |
| 22359464 | Are Toll-like receptor gene polymorphisms associated with prostate cancer? | Kutikhin AG et al. | 2012 | Cancer management and research |
| 22494793 | Innate immunity gene single nucleotide polymorphisms and otitis media. | Carroll SR et al. | 2012 | International journal of pediatric otorhinolaryngology |
| 22529866 | Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection. | Hart BE et al. | 2012 | Journal of tropical medicine |
| 22662111 | Polymorphisms in Toll-like receptors 2, 4, and 9 are highly associated with hearing loss in survivors of bacterial meningitis. | van Well GT et al. | 2012 | PloS one |
| 22952638 | Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease. | Budulac SE et al. | 2012 | PloS one |
| 22992740 | R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88. | Xiong Y et al. | 2012 | The Journal of biological chemistry |
| 23112821 | Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data. | Baker AR et al. | 2012 | PloS one |
| 23151015 | Toll-like receptor 3 gene polymorphisms and severity of pandemic A/H1N1/2009 influenza in otherwise healthy children. | Esposito S et al. | 2012 | Virology journal |
| 23289617 | Genetic variation of TLR2 and TLR4 among the Saudi Arabian population: insight into the evolutionary dynamics of the Arabian Peninsula. | Abu-Amero KK et al. | 2013 | Genetic testing and molecular biomarkers |
| 23316245 | The host genetic diversity in malaria infection. | de Mendonça VR et al. | 2012 | Journal of tropical medicine |
| 23390954 | Three multiplex snapshot assays for SNP genotyping in candidate innate immune genes. | Esteves LM et al. | 2013 | BMC research notes |
| 23417289 | Coding variants of TLR2 and TLR4 genes do not substantially contribute to prosthetic joint infection. | Mrazek F et al. | 2013 | Inflammation research |
| 23776356 | Allergic rhinitis and genetic components: focus on Toll-like receptors (TLRs) gene polymorphism. | Gao Z et al. | 2010 | The application of clinical genetics |
| 23992203 | TLR-2 gene polymorphisms and susceptibility to cancer: evidence from meta-analysis. | Wang XQ et al. | 2013 | Genetic testing and molecular biomarkers |
| 23994582 | Genetic variations in toll-like receptor pathway and lung function decline in Cystic fibrosis patients. | Haerynck F et al. | 2013 | Human immunology |
| 24053111 | Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population. | Torres-García D et al. | 2013 | Journal of translational medicine |
| 25000179 | Genetic polymorphisms and sepsis in premature neonates. | Esposito S et al. | 2014 | PloS one |
| 25020893 | ||||
| 25213166 | An association between single nucleotide polymorphisms within TLR and TREM-1 genes and infective endocarditis. | Golovkin AS et al. | 2015 | Cytokine |
| 25482673 | TLR2, TLR4 and CD86 gene polymorphisms in recurrent aphthous stomatitis. | Karasneh J et al. | 2015 | Journal of oral pathology & medicine |
| 25516666 | Cytokine production in patients with cirrhosis and TLR4 polymorphisms. | Nieto JC et al. | 2014 | World journal of gastroenterology |
| 25541970 | The influence of the CHIEF pathway on colorectal cancer-specific mortality. | Slattery ML et al. | 2014 | PloS one |
| 25560985 | Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious diseases. | Skevaki C et al. | 2015 | Clinical and experimental immunology |
| 25590839 | TLR4 rs1927911, but not TLR2 rs5743708, is associated with atherosclerotic cerebral infarction in the Southern Han population: a case-control study. | Song Y et al. | 2015 | Medicine |
| 25605403 | Toll-like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette-Guérin osteitis following newborn vaccination. | Pöyhönen L et al. | 2015 | Acta paediatrica (Oslo, Norway |
| 25807366 | Urinary proteins, vitamin D and genetic polymorphisms as risk factors for febrile urinary tract infection and relation with bacteremia: a case control study. | van der Starre WE et al. | 2015 | PloS one |
| 26023918 | Association between TLR2 and TLR4 Gene Polymorphisms and the Susceptibility to Inflammatory Bowel Disease: A Meta-Analysis. | Cheng Y et al. | 2015 | PloS one |
| 26079505 | Genetic polymorphisms in pattern recognition receptors and risk of periodontitis: Evidence based on 12,793 subjects. | Han MX et al. | 2015 | Human immunology |
| 26398587 | Toll-Like Receptors 2 and 4 Polymorphisms in Age-Related Macular Degeneration. | Güven M et al. | 2016 | Current eye research |
| 26430737 | TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis. | Schurz H et al. | 2015 | PloS one |
| 26524966 | The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis. | Patarčić I et al. | 2015 | Scientific reports |
| 26741133 | Gene Polymorphism of Toll-Like Receptors and Lung Function at Five to Seven Years of Age after Infant Bronchiolitis. | Lauhkonen E et al. | 2016 | PloS one |
| 26963509 | Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia. | Fischer M et al. | 2016 | PloS one |
| 26986131 | Human Cytokine Genetic Variants Associated With HBsAg Reverse Seroconversion in Rituximab-Treated Non-Hodgkin Lymphoma Patients. | Hsiao LT et al. | 2016 | Medicine |
| 27004062 | Molecular Genetic of Atopic dermatitis: An Update. | Al-Shobaili HA et al. | 2016 | International journal of health sciences |
| 27124026 | 25-Hydroxy Vitamin D, Vitamin D Receptor and Toll-like Receptor 2 Polymorphisms in Spinal Tuberculosis: A Case-Control Study. | Panwar A et al. | 2016 | Medicine |
| 27155792 | TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients. | Shi G et al. | 2016 | Journal of dermatological science |
| 27200266 | Association of TLR and TREM-1 gene polymorphisms with atherosclerosis severity in a Russian population. | Kutikhin AG et al. | 2016 | Meta gene |
| 27240411 | N. meningitidis and TLR Polymorphisms: A Fascinating Immunomodulatory Network. | Gianchecchi E et al. | 2016 | Vaccines |
| 27247849 | Genetic variation and cognitive dysfunction in opioid-treated patients with cancer. | Kurita GP et al. | 2016 | Brain and behavior |
| 27432718 | Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome. | Ferwerda B et al. | 2016 | EBioMedicine |
| 27498757 | Post-bronchiolitis wheezing is associated with toll-like receptor 9 rs187084 gene polymorphism. | Nuolivirta K et al. | 2016 | Scientific reports |
| 27507606 | The Correlation of Increased CRP Levels with NFKB1 and TLR2 Polymorphisms in the Case of Morbid Obesity. | Soydas T et al. | 2016 | Scandinavian journal of immunology |
| 27586547 | Host genetics and susceptibility to congenital and childhood cytomegalovirus infection: a systematic review. | Gelemanović A et al. | 2016 | Croatian medical journal |
| 27589735 | A Genomics-Based Model for Prediction of Severe Bioprosthetic Mitral Valve Calcification. | Ponasenko AV et al. | 2016 | International journal of molecular sciences |
| 27713886 | The role of genetics and antibodies in sepsis. | Giamarellos-Bourboulis EJ et al. | 2016 | Annals of translational medicine |
| 27725770 | Genetic dissection of host immune response in pneumonia development and progression. | Smelaya TV et al. | 2016 | Scientific reports |
| 28046022 | Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children. | Studzińska M et al. | 2017 | PloS one |
| 28148965 | Rapid detection of functional gene polymorphisms of TLRs and IL-17 using high resolution melting analysis. | Teräsjärvi J et al. | 2017 | Scientific reports |
| 28340580 | Toll-like receptors genes polymorphisms and the occurrence of HCMV infection among pregnant women. | Wujcicka W et al. | 2017 | Virology journal |
| 28411367 | Serum 25(OH)D concentration, common variants of the VDR gene and lung cancer occurrence. | Gromowski T et al. | 2017 | International journal of cancer |
| 28443596 | Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey. | Can C et al. | 2017 | Balkan medical journal |
| 28487240 | Analysis of TLR2, TLR4, and TLR9 single nucleotide polymorphisms in children with bacterial meningitis and their healthy family members. | Gowin E et al. | 2017 | International journal of infectious diseases |
| 28514297 | Association of single-nucleotide polymorphisms in toll-like receptor 2 gene with asthma susceptibility: A meta-analysis. | Gao Y et al. | 2017 | Medicine |
| 28518213 | Relationship between toll-like receptor 2 R753Q and T16934A polymorphisms and Staphylococcus aureus nasal carriage. | Żukowski M et al. | 2017 | Anaesthesiology intensive therapy |
| 29320990 | Correlation between polymorphisms in toll-like receptor genes and the activity of hepatitis B virus among treatment-naïve patients: a case-control study in a Han Chinese population. | Lin Y et al. | 2018 | BMC infectious diseases |
| 29675696 | Association of Toll like receptor 2 and 9 gene variants with pulmonary tuberculosis: exploration in a northern Indian population. | Mittal M et al. | 2018 | Molecular biology reports |
| 29805910 | Genetic Diversity of IFγ, IL1β, TLR2, and TLR8 Loci in Pulmonary Tuberculosis in Kazakhstan. | Yerezhepov D et al. | 2014 | Central Asian journal of global health |
| 29854884 | Arg753gln and Arg677 Trp Polymorphisms of Toll-Like Receptor 2 In Acute Apical Abscess. | Miri-Moghaddam E et al. | 2018 | Journal of dentistry (Shiraz, Iran) |
| 29909409 | The Possible Role of Gene Variant Coding Nonfunctional Toll-Like Receptor 2 in the Pathogenesis of Mastocytosis. | Nedoszytko B et al. | 2018 | International archives of allergy and immunology |
| 30481307 | Polymorphisms in TLR4 and TNFA and Risk of Mycobacterium tuberculosis Infection and Development of Active Disease in Contacts of Tuberculosis Cases in Brazil: A Prospective Cohort Study. | Cubillos-Angulo JM et al. | 2019 | Clinical infectious diseases |
| 31396258 | Host Genetics of Cytomegalovirus Pathogenesis. | Sezgin E et al. | 2019 | Frontiers in genetics |
| 31656159 | Arg753Gln Polymorphisms in the Toll-Like Receptor 2 Gene are Associated with Cytomegalovirus Infection in Egyptian Bone Marrow Recipients. | El-Nabi SH et al. | 2020 | Endocrine, metabolic & immune disorders drug targets |
| 31710083 | -196 to -174del, rs4696480, rs3804099 polymorphisms of Toll-like receptor 2 gene impact the susceptibility of cancers: evidence from 37053 subjects. | Gao SL et al. | 2019 | Bioscience reports |
| 31781672 | Genetic Polymorphisms of <i>Toll-like receptors 2</i> and <i>9</i> as Susceptibility Factors for the Development of Ankylosing Spondylitis and Psoriatic Arthritis. | Oliveira-Toré CF et al. | 2019 | Journal of immunology research |
| 31845221 | Dectin-1 rs3901533 and rs7309123 Polymorphisms Increase Susceptibility to Pulmonary Invasive Fungal Disease in Patients with Acute Myeloid Leukemia from a Chinese Han Population. | Chen MJ et al. | 2019 | Current medical science |
| 31856358 | Toll-like receptor 10 rs4129009 gene polymorphism is associated with post-bronchiolitis lung function in adolescence. | Riikonen R et al. | 2020 | Acta paediatrica (Oslo, Norway |
| 32421725 | Association between single nucleotide polymorphisms (SNPs) of IL1, IL12, IL28 and TLR4 and symptoms of congenital cytomegalovirus infection. | Jedlińska-Pijanowska D et al. | 2020 | PloS one |
| 32753695 | TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis. | Jabłońska A et al. | 2020 | Scientific reports |
| 32831974 | Association of TLR-2 Gene Polymorphisms with the Risk of Periodontitis: A Meta-Analysis. | Shan C et al. | 2020 | Disease markers |
| 33077622 | The Arg753Gln Polymorphism of Toll-Like Receptor 2 Has a Lower Occurrence in Patients with Syphilis, Suggesting Its Protective Effect in Czech and Slovak Individuals. | Grillová L et al. | 2020 | Infection and immunity |
| 33350746 | Association of toll-like receptor polymorphisms with acquisition of HIV infection and clinical findings: A protocol for systematic review and meta-analysis. | Shi H et al. | 2020 | Medicine |
| 33512737 | A case-control study examining the association of smad7 and TLR single nucleotide polymorphisms on the risk of colorectal cancer in ulcerative colitis. | Reilly F et al. | 2021 | Colorectal disease |
| 33656306 | Association between single nucleotide polymorphisms and viral load in congenital cytomegalovirus infection. | Jedlińska-Pijanowska D et al. | 2021 | Journal of mother and child |
The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.
Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.