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dbSNP Short Genetic Variations

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs324420

Current Build 152

Released October 2, 2018

Organism
Homo sapiens
Position
chr1:46405089 (GRCh38.p12) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
C>A
Variation Type
SNV Single Nucleotide Variation
Frequency
A=0.23598 (58089/246162, GnomAD)
A=0.25707 (32280/125568, TOPMED)
A=0.23331 (28270/121168, ExAC) (+ 5 more)
A=0.2758 (8512/30866, GnomAD)
A=0.262 (1310/5008, 1000G)
A=0.298 (1337/4480, Estonian)
A=0.190 (731/3854, ALSPAC)
A=0.206 (765/3708, TWINSUK)
Clinical Significance
Reported in ClinVar
Gene : Consequence
FAAH : Missense Variant
Publications
63 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p12 chr 1 NC_000001.11:g.46405089C>A
GRCh37.p13 chr 1 NC_000001.10:g.46870761C>A
FAAH RefSeqGene NG_012195.1:g.15823C>A
Gene: FAAH, fatty acid amide hydrolase (plus strand)
Molecule type Change Amino acid[Codon] SO Term
FAAH transcript NM_001441.2:c.385C>A P [CCA] > T [ACA] Coding Sequence Variant
fatty-acid amide hydrolase 1 NP_001432.2:p.Pro129Thr P (Pro) > T (Thr) Missense Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: A (allele ID: 21763 )
ClinVar Accession Disease Names Clinical Significance
RCV000007116.3 Polysubstance abuse, susceptibility to Risk-Factor
Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
gnomAD - Exomes Global Study-wide 246162 C=0.76402 A=0.23598
gnomAD - Exomes European Sub 133938 C=0.78169 A=0.21831
gnomAD - Exomes Asian Sub 48022 C=0.8119 A=0.1881
gnomAD - Exomes American Sub 33578 C=0.6533 A=0.3467
gnomAD - Exomes African Sub 15296 C=0.6439 A=0.3561
gnomAD - Exomes Ashkenazi Jewish Sub 9846 C=0.851 A=0.149
gnomAD - Exomes Other Sub 5482 C=0.770 A=0.230
TopMed Global Study-wide 125568 C=0.74293 A=0.25707
ExAC Global Study-wide 121168 C=0.76669 A=0.23331
ExAC Europe Sub 73180 C=0.7877 A=0.2123
ExAC Asian Sub 25134 C=0.8120 A=0.1880
ExAC American Sub 11564 C=0.6427 A=0.3573
ExAC African Sub 10388 C=0.6456 A=0.3544
ExAC Other Sub 902 C=0.78 A=0.22
gnomAD - Genomes Global Study-wide 30866 C=0.7242 A=0.2758
gnomAD - Genomes European Sub 18444 C=0.7571 A=0.2429
gnomAD - Genomes African Sub 8694 C=0.636 A=0.364
gnomAD - Genomes East Asian Sub 1612 C=0.827 A=0.173
gnomAD - Genomes Other Sub 978 C=0.74 A=0.26
gnomAD - Genomes American Sub 836 C=0.66 A=0.34
gnomAD - Genomes Ashkenazi Jewish Sub 302 C=0.83 A=0.17
1000Genomes Global Study-wide 5008 C=0.738 A=0.262
1000Genomes African Sub 1322 C=0.632 A=0.368
1000Genomes East Asian Sub 1008 C=0.824 A=0.176
1000Genomes Europe Sub 1006 C=0.789 A=0.211
1000Genomes South Asian Sub 978 C=0.80 A=0.20
1000Genomes American Sub 694 C=0.65 A=0.35
Genetic variation in the Estonian population Estonian Study-wide 4480 C=0.702 A=0.298
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 C=0.810 A=0.190
UK 10K study - Twins TWIN COHORT Study-wide 3708 C=0.794 A=0.206
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement C= A Note
GRCh38.p12 chr 1 NC_000001.11:g.46405089C= NC_000001.11:g.46405089C>A
GRCh37.p13 chr 1 NC_000001.10:g.46870761C= NC_000001.10:g.46870761C>A
FAAH RefSeqGene NG_012195.1:g.15823C= NG_012195.1:g.15823C>A
FAAH transcript NM_001441.2:c.385C= NM_001441.2:c.385C>A
fatty-acid amide hydrolase 1 NP_001432.2:p.Pro129= NP_001432.2:p.Pro129Thr
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

137 SubSNP, 8 Frequency, 1 ClinVar submissions
No Submitter Submission ID Date (Build)
1 KWOK ss414956 Jul 12, 2000 (79)
2 SC_JCM ss587534 Jul 16, 2000 (80)
3 KWOK ss1925495 Oct 18, 2000 (87)
4 KWOK ss1925873 Oct 18, 2000 (87)
5 SC_JCM ss2600464 Nov 08, 2000 (89)
6 SC_SNP ss13019202 Dec 05, 2003 (119)
7 CGAP-GAI ss16262214 Feb 27, 2004 (120)
8 CSHL-HAPMAP ss16395434 Feb 27, 2004 (120)
9 SSAHASNP ss20535610 Apr 05, 2004 (121)
10 ABI ss44084610 Mar 14, 2006 (126)
11 ILLUMINA ss65727425 Oct 16, 2006 (127)
12 ILLUMINA ss66584665 Dec 02, 2006 (127)
13 EGP_SNPS ss66860923 Dec 02, 2006 (127)
14 ILLUMINA ss67293310 Dec 02, 2006 (127)
15 ILLUMINA ss67697191 Dec 02, 2006 (127)
16 PERLEGEN ss68765097 May 18, 2007 (127)
17 EGP_SNPS ss70455703 May 18, 2007 (127)
18 ILLUMINA ss70771906 May 24, 2008 (130)
19 ILLUMINA ss71347329 May 18, 2007 (127)
20 ILLUMINA ss74962542 Dec 06, 2007 (129)
21 HGSV ss79030855 Dec 06, 2007 (129)
22 ILLUMINA ss79160397 Dec 14, 2007 (130)
23 KRIBB_YJKIM ss83427387 Dec 14, 2007 (130)
24 CORNELL ss86240994 Mar 23, 2008 (129)
25 HUMANGENOME_JCVI ss99205092 Feb 04, 2009 (130)
26 1000GENOMES ss108170325 Jan 23, 2009 (130)
27 1000GENOMES ss110384633 Jan 24, 2009 (130)
28 ILLUMINA-UK ss118662550 Feb 14, 2009 (130)
29 ILLUMINA ss122182448 Dec 01, 2009 (131)
30 ENSEMBL ss138955092 Dec 01, 2009 (131)
31 ILLUMINA ss154257386 Dec 01, 2009 (131)
32 ILLUMINA ss159433884 Dec 01, 2009 (131)
33 SEATTLESEQ ss159697386 Dec 01, 2009 (131)
34 ILLUMINA ss160617187 Dec 01, 2009 (131)
35 COMPLETE_GENOMICS ss163344459 Jul 04, 2010 (132)
36 COMPLETE_GENOMICS ss166460748 Jul 04, 2010 (132)
37 OMICIA ss169614834 Aug 28, 2012 (137)
38 ILLUMINA ss171565310 Jul 04, 2010 (132)
39 ILLUMINA ss173578227 Jul 04, 2010 (132)
40 BUSHMAN ss198394442 Jul 04, 2010 (132)
41 BCM-HGSC-SUB ss205493694 Jul 04, 2010 (132)
42 1000GENOMES ss218357905 Jul 14, 2010 (132)
43 1000GENOMES ss230515606 Jul 14, 2010 (132)
44 1000GENOMES ss238213716 Jul 15, 2010 (132)
45 ILLUMINA ss244294464 Jul 04, 2010 (132)
46 OMIM-CURATED-RECORDS ss256302018 Aug 26, 2010 (132)
47 GMI ss275807551 May 04, 2012 (137)
48 GMI ss284042340 Apr 25, 2013 (138)
49 PJP ss290502567 May 09, 2011 (134)
50 NHLBI-ESP ss341962127 May 09, 2011 (134)
51 ILLUMINA ss480771103 May 04, 2012 (137)
52 ILLUMINA ss480786925 May 04, 2012 (137)
53 ILLUMINA ss481683308 Sep 08, 2015 (146)
54 ILLUMINA ss485180275 May 04, 2012 (137)
55 1000GENOMES ss489741590 May 04, 2012 (137)
56 GSK-GENETICS ss491233572 May 04, 2012 (137)
57 EXOME_CHIP ss491293280 May 04, 2012 (137)
58 CLINSEQ_SNP ss491594126 May 04, 2012 (137)
59 ILLUMINA ss537169500 Sep 08, 2015 (146)
60 TISHKOFF ss554061138 Apr 25, 2013 (138)
61 SSMP ss647858782 Apr 25, 2013 (138)
62 ILLUMINA ss778890149 Sep 08, 2015 (146)
63 ILLUMINA ss780852131 Sep 08, 2015 (146)
64 ILLUMINA ss783036308 Sep 08, 2015 (146)
65 ILLUMINA ss783536041 Sep 08, 2015 (146)
66 ILLUMINA ss783995808 Sep 08, 2015 (146)
67 ILLUMINA ss825490915 Apr 01, 2015 (144)
68 ILLUMINA ss832293984 Sep 08, 2015 (146)
69 ILLUMINA ss834351248 Sep 08, 2015 (146)
70 JMKIDD_LAB ss974435084 Aug 21, 2014 (142)
71 EVA-GONL ss975104247 Aug 21, 2014 (142)
72 JMKIDD_LAB ss1067420944 Aug 21, 2014 (142)
73 JMKIDD_LAB ss1067845325 Aug 21, 2014 (142)
74 1000GENOMES ss1290665023 Aug 21, 2014 (142)
75 DDI ss1425792404 Apr 01, 2015 (144)
76 EVA_GENOME_DK ss1574028037 Apr 01, 2015 (144)
77 EVA_FINRISK ss1584007791 Apr 01, 2015 (144)
78 EVA_DECODE ss1584468348 Apr 01, 2015 (144)
79 EVA_UK10K_ALSPAC ss1600056269 Apr 01, 2015 (144)
80 EVA_UK10K_TWINSUK ss1643050302 Apr 01, 2015 (144)
81 EVA_EXAC ss1685532068 Apr 01, 2015 (144)
82 EVA_MGP ss1710903844 Apr 01, 2015 (144)
83 EVA_SVP ss1712328937 Apr 01, 2015 (144)
84 ILLUMINA ss1751922054 Sep 08, 2015 (146)
85 ILLUMINA ss1751922055 Sep 08, 2015 (146)
86 HAMMER_LAB ss1794280150 Sep 08, 2015 (146)
87 ILLUMINA ss1917728250 Feb 12, 2016 (147)
88 WEILL_CORNELL_DGM ss1918312470 Feb 12, 2016 (147)
89 ILLUMINA ss1945993861 Feb 12, 2016 (147)
90 ILLUMINA ss1945993862 Feb 12, 2016 (147)
91 ILLUMINA ss1958268695 Feb 12, 2016 (147)
92 ILLUMINA ss1958268697 Feb 12, 2016 (147)
93 GENOMED ss1966735247 Jul 19, 2016 (147)
94 JJLAB ss2019671756 Sep 14, 2016 (149)
95 USC_VALOUEV ss2147684182 Dec 20, 2016 (150)
96 HUMAN_LONGEVITY ss2162033239 Dec 20, 2016 (150)
97 TOPMED ss2324252914 Dec 20, 2016 (150)
98 ILLUMINA ss2632508923 Nov 08, 2017 (151)
99 GRF ss2697594781 Nov 08, 2017 (151)
100 ILLUMINA ss2710671047 Nov 08, 2017 (151)
101 GNOMAD ss2731473167 Nov 08, 2017 (151)
102 GNOMAD ss2746324053 Nov 08, 2017 (151)
103 GNOMAD ss2754495776 Nov 08, 2017 (151)
104 AFFY ss2984858125 Nov 08, 2017 (151)
105 AFFY ss2985507320 Nov 08, 2017 (151)
106 SWEGEN ss2986725176 Nov 08, 2017 (151)
107 ILLUMINA ss3021083175 Nov 08, 2017 (151)
108 ILLUMINA ss3021083176 Nov 08, 2017 (151)
109 BIOINF_KMB_FNS_UNIBA ss3023598477 Nov 08, 2017 (151)
110 TOPMED ss3075137132 Nov 08, 2017 (151)
111 CSHL ss3343431597 Nov 08, 2017 (151)
112 ILLUMINA ss3625534692 Oct 11, 2018 (152)
113 ILLUMINA ss3626085450 Oct 11, 2018 (152)
114 ILLUMINA ss3626085451 Oct 11, 2018 (152)
115 ILLUMINA ss3630545479 Oct 11, 2018 (152)
116 ILLUMINA ss3632889562 Oct 11, 2018 (152)
117 ILLUMINA ss3633584047 Oct 11, 2018 (152)
118 ILLUMINA ss3634321794 Oct 11, 2018 (152)
119 ILLUMINA ss3634321795 Oct 11, 2018 (152)
120 ILLUMINA ss3635277963 Oct 11, 2018 (152)
121 ILLUMINA ss3635997093 Oct 11, 2018 (152)
122 ILLUMINA ss3637028372 Oct 11, 2018 (152)
123 ILLUMINA ss3637753257 Oct 11, 2018 (152)
124 ILLUMINA ss3638895996 Oct 11, 2018 (152)
125 ILLUMINA ss3639445382 Oct 11, 2018 (152)
126 ILLUMINA ss3640029155 Oct 11, 2018 (152)
127 ILLUMINA ss3640029156 Oct 11, 2018 (152)
128 ILLUMINA ss3640979667 Oct 11, 2018 (152)
129 ILLUMINA ss3641273590 Oct 11, 2018 (152)
130 ILLUMINA ss3642765718 Oct 11, 2018 (152)
131 ILLUMINA ss3644489767 Oct 11, 2018 (152)
132 ILLUMINA ss3644489768 Oct 11, 2018 (152)
133 OMUKHERJEE_ADBS ss3646230107 Oct 11, 2018 (152)
134 URBANLAB ss3646652979 Oct 11, 2018 (152)
135 ILLUMINA ss3651409317 Oct 11, 2018 (152)
136 ILLUMINA ss3651409318 Oct 11, 2018 (152)
137 ILLUMINA ss3653630482 Oct 11, 2018 (152)
138 1000Genomes NC_000001.10 - 46870761 Oct 11, 2018 (152)
139 The Avon Longitudinal Study of Parents and Children NC_000001.10 - 46870761 Oct 11, 2018 (152)
140 Genetic variation in the Estonian population NC_000001.10 - 46870761 Oct 11, 2018 (152)
141 ExAC NC_000001.10 - 46870761 Oct 11, 2018 (152)
142 gnomAD - Genomes NC_000001.10 - 46870761 Oct 11, 2018 (152)
143 gnomAD - Exomes NC_000001.10 - 46870761 Oct 11, 2018 (152)
144 TopMed NC_000001.11 - 46405089 Oct 11, 2018 (152)
145 UK 10K study - Twins NC_000001.10 - 46870761 Oct 11, 2018 (152)
146 ClinVar RCV000007116.3 Oct 11, 2018 (152)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs57947754 May 24, 2008 (130)
Added to this RefSNP Cluster:
Submission ids Observation SPDI Canonical SPDI Source RSIDs
ss79030855, ss3638895996, ss3639445382 NC_000001.8:46582780:C= NC_000001.11:46405088:C= (self)
ss108170325, ss110384633, ss118662550, ss163344459, ss166460748, ss198394442, ss205493694, ss275807551, ss284042340, ss290502567, ss480771103, ss491233572, ss491594126, ss825490915, ss1584468348, ss1712328937, ss3642765718 NC_000001.9:46643347:C= NC_000001.11:46405088:C= (self)
1375457, 747640, 528254, 4727415, 3894975, 380440, 747640, ss218357905, ss230515606, ss238213716, ss341962127, ss480786925, ss481683308, ss485180275, ss489741590, ss491293280, ss537169500, ss554061138, ss647858782, ss778890149, ss780852131, ss783036308, ss783536041, ss783995808, ss832293984, ss834351248, ss974435084, ss975104247, ss1067420944, ss1067845325, ss1290665023, ss1425792404, ss1574028037, ss1584007791, ss1600056269, ss1643050302, ss1685532068, ss1710903844, ss1751922054, ss1751922055, ss1794280150, ss1917728250, ss1918312470, ss1945993861, ss1945993862, ss1958268695, ss1958268697, ss1966735247, ss2019671756, ss2147684182, ss2324252914, ss2632508923, ss2697594781, ss2710671047, ss2731473167, ss2746324053, ss2754495776, ss2984858125, ss2985507320, ss2986725176, ss3021083175, ss3021083176, ss3343431597, ss3625534692, ss3626085450, ss3626085451, ss3630545479, ss3632889562, ss3633584047, ss3634321794, ss3634321795, ss3635277963, ss3635997093, ss3637028372, ss3637753257, ss3640029155, ss3640029156, ss3640979667, ss3641273590, ss3644489767, ss3644489768, ss3646230107, ss3651409317, ss3651409318, ss3653630482 NC_000001.10:46870760:C= NC_000001.11:46405088:C= (self)
7106192, ss169614834, ss256302018, ss2162033239, ss3023598477, ss3075137132, ss3646652979 NC_000001.11:46405088:C= NC_000001.11:46405088:C= (self)
ss13019202 NT_004852.15:3210026:C= NC_000001.11:46405088:C= (self)
ss16395434, ss20535610 NT_032977.6:8433830:C= NC_000001.11:46405088:C= (self)
ss414956, ss587534, ss1925495, ss1925873, ss2600464, ss16262214, ss44084610, ss65727425, ss66584665, ss66860923, ss67293310, ss67697191, ss68765097, ss70455703, ss70771906, ss71347329, ss74962542, ss79160397, ss83427387, ss86240994, ss99205092, ss122182448, ss138955092, ss154257386, ss159433884, ss159697386, ss160617187, ss171565310, ss173578227, ss244294464 NT_032977.9:16842678:C= NC_000001.11:46405088:C= (self)
ss79030855, ss3638895996, ss3639445382 NC_000001.8:46582780:C>A NC_000001.11:46405088:C>A (self)
ss108170325, ss110384633, ss118662550, ss163344459, ss166460748, ss198394442, ss205493694, ss275807551, ss284042340, ss290502567, ss480771103, ss491233572, ss491594126, ss825490915, ss1584468348, ss1712328937, ss3642765718 NC_000001.9:46643347:C>A NC_000001.11:46405088:C>A (self)
1375457, 747640, 528254, 4727415, 3894975, 380440, 747640, ss218357905, ss230515606, ss238213716, ss341962127, ss480786925, ss481683308, ss485180275, ss489741590, ss491293280, ss537169500, ss554061138, ss647858782, ss778890149, ss780852131, ss783036308, ss783536041, ss783995808, ss832293984, ss834351248, ss974435084, ss975104247, ss1067420944, ss1067845325, ss1290665023, ss1425792404, ss1574028037, ss1584007791, ss1600056269, ss1643050302, ss1685532068, ss1710903844, ss1751922054, ss1751922055, ss1794280150, ss1917728250, ss1918312470, ss1945993861, ss1945993862, ss1958268695, ss1958268697, ss1966735247, ss2019671756, ss2147684182, ss2324252914, ss2632508923, ss2697594781, ss2710671047, ss2731473167, ss2746324053, ss2754495776, ss2984858125, ss2985507320, ss2986725176, ss3021083175, ss3021083176, ss3343431597, ss3625534692, ss3626085450, ss3626085451, ss3630545479, ss3632889562, ss3633584047, ss3634321794, ss3634321795, ss3635277963, ss3635997093, ss3637028372, ss3637753257, ss3640029155, ss3640029156, ss3640979667, ss3641273590, ss3644489767, ss3644489768, ss3646230107, ss3651409317, ss3651409318, ss3653630482 NC_000001.10:46870760:C>A NC_000001.11:46405088:C>A (self)
RCV000007116.3, 7106192, ss169614834, ss256302018, ss2162033239, ss3023598477, ss3075137132, ss3646652979 NC_000001.11:46405088:C>A NC_000001.11:46405088:C>A (self)
ss13019202 NT_004852.15:3210026:C>A NC_000001.11:46405088:C>A (self)
ss16395434, ss20535610 NT_032977.6:8433830:C>A NC_000001.11:46405088:C>A (self)
ss414956, ss587534, ss1925495, ss1925873, ss2600464, ss16262214, ss44084610, ss65727425, ss66584665, ss66860923, ss67293310, ss67697191, ss68765097, ss70455703, ss70771906, ss71347329, ss74962542, ss79160397, ss83427387, ss86240994, ss99205092, ss122182448, ss138955092, ss154257386, ss159433884, ss159697386, ss160617187, ss171565310, ss173578227, ss244294464 NT_032977.9:16842678:C>A NC_000001.11:46405088:C>A (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

63 citations for rs324420
PMID Title Author Year Journal
12060782 A missense mutation in human fatty acid amide hydrolase associated with problem drug use. Sipe JC et al. 2002 Proceedings of the National Academy of Sciences of the United States of America
15254019 Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use. Chiang KP et al. 2004 Human molecular genetics
15986317 Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. Oliveira SA et al. 2005 American journal of human genetics
16882734 Genetic predictors for acute experimental cold and heat pain sensitivity in humans. Kim H et al. 2006 Journal of medical genetics
16972078 The fatty acid amide hydrolase 385 A/A (P129T) variant: haplotype analysis of an ancient missense mutation and validation of risk for drug addiction. Flanagan JM et al. 2006 Human genetics
17216208 The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites. Jensen DP et al. 2007 Journal of molecular medicine (Berlin, Germany)
17847002 An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. Shen GQ et al. 2007 American journal of human genetics
17991615 Rapid screening for potentially relevant polymorphisms in the human fatty acid amide hydrolase gene using Pyrosequencing. Doehring A et al. 2007 Prostaglandins & other lipid mediators
18705688 Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes. Haughey HM et al. 2008 Addiction (Abingdon, England)
19002671 Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis. Schacht JP et al. 2009 Psychopharmacology
19014633 Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa. Müller TD et al. 2008 Child and adolescent psychiatry and mental health
19053981 The role of fatty acid hydrolase gene variants in inflammatory bowel disease. Storr M et al. 2009 Alimentary pharmacology & therapeutics
19165169 Variants in the CNR1 and the FAAH genes and adiposity traits in the community. Lieb W et al. 2009 Obesity (Silver Spring, Md.)
19335651 Candidate genes for cannabis use disorders: findings, challenges and directions. Agrawal A et al. 2009 Addiction (Abingdon, England)
19659925 Association of CNR1 and FAAH endocannabinoid gene polymorphisms with anorexia nervosa and bulimia nervosa: evidence for synergistic effects. Monteleone P et al. 2009 Genes, brain, and behavior
19890266 More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine. Dlugos AM et al. 2010 Neuropsychopharmacology
19958092 Obesity-related dyslipidemia associated with FAAH, independent of insulin response, in multigenerational families of Northern European descent. Zhang Y et al. 2009 Pharmacogenomics
20010552 Individual and additive effects of the CNR1 and FAAH genes on brain response to marijuana cues. Filbey FM et al. 2010 Neuropsychopharmacology
20033240 Eating disorders: the current status of molecular genetic research. Scherag S et al. 2010 European child & adolescent psychiatry
20044928 Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity. Müller TD et al. 2010 BMC medical genetics
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Genomic regions, transcripts, and products
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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
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