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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2280883

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chrX:49252667 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
T>C
Variation Type
SNV Single Nucleotide Variation
Frequency
C=0.287057 (75981/264690, TOPMED)
C=0.415961 (87465/210272, ALFA)
C=0.302362 (30391/100512, GnomAD) (+ 13 more)
C=0.18951 (2432/12833, 8.3KJPN)
C=0.2262 (854/3775, 1000G)
C=0.4531 (1680/3708, TWINSUK)
C=0.1765 (515/2918, KOREAN)
C=0.4517 (1305/2889, ALSPAC)
C=0.2841 (592/2084, HGDP_Stanford)
C=0.2040 (386/1892, HapMap)
T=0.174 (31/178, SGDP_PRJ)
C=0.361 (39/108, Qatari)
C=0.38 (18/48, Ancient Sardinia)
C=0.13 (6/47, Vietnamese)
C=0.40 (16/40, GENOME_DK)
T=0.28 (5/18, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
FOXP3 : Intron Variant
Publications
15 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 210272 T=0.584039 C=0.415961
European Sub 185550 T=0.561169 C=0.438831
African Sub 6120 T=0.9294 C=0.0706
African Others Sub 236 T=0.975 C=0.025
African American Sub 5884 T=0.9276 C=0.0724
Asian Sub 1656 T=0.8134 C=0.1866
East Asian Sub 1406 T=0.8243 C=0.1757
Other Asian Sub 250 T=0.752 C=0.248
Latin American 1 Sub 614 T=0.624 C=0.376
Latin American 2 Sub 5872 T=0.7660 C=0.2340
South Asian Sub 5176 T=0.6776 C=0.3224
Other Sub 5284 T=0.6168 C=0.3832


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 T=0.712943 C=0.287057
Allele Frequency Aggregator Total Global 210272 T=0.584039 C=0.415961
Allele Frequency Aggregator European Sub 185550 T=0.561169 C=0.438831
Allele Frequency Aggregator African Sub 6120 T=0.9294 C=0.0706
Allele Frequency Aggregator Latin American 2 Sub 5872 T=0.7660 C=0.2340
Allele Frequency Aggregator Other Sub 5284 T=0.6168 C=0.3832
Allele Frequency Aggregator South Asian Sub 5176 T=0.6776 C=0.3224
Allele Frequency Aggregator Asian Sub 1656 T=0.8134 C=0.1866
Allele Frequency Aggregator Latin American 1 Sub 614 T=0.624 C=0.376
gnomAD - Genomes Global Study-wide 100512 T=0.697638 C=0.302362
gnomAD - Genomes European Sub 55363 T=0.57060 C=0.42940
gnomAD - Genomes African Sub 30186 T=0.92453 C=0.07547
gnomAD - Genomes American Sub 8808 T=0.7337 C=0.2663
gnomAD - Genomes Ashkenazi Jewish Sub 2483 T=0.5614 C=0.4386
gnomAD - Genomes East Asian Sub 2150 T=0.8028 C=0.1972
gnomAD - Genomes Other Sub 1522 T=0.6840 C=0.3160
8.3KJPN JAPANESE Study-wide 12833 T=0.81049 C=0.18951
1000Genomes Global Study-wide 3775 T=0.7738 C=0.2262
1000Genomes African Sub 1003 T=0.9761 C=0.0239
1000Genomes Europe Sub 766 T=0.539 C=0.461
1000Genomes East Asian Sub 764 T=0.834 C=0.166
1000Genomes South Asian Sub 718 T=0.714 C=0.286
1000Genomes American Sub 524 T=0.723 C=0.277
UK 10K study - Twins TWIN COHORT Study-wide 3708 T=0.5469 C=0.4531
KOREAN population from KRGDB KOREAN Study-wide 2918 T=0.8235 C=0.1765
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 2889 T=0.5483 C=0.4517
HGDP-CEPH-db Supplement 1 Global Study-wide 2084 T=0.7159 C=0.2841
HGDP-CEPH-db Supplement 1 Est_Asia Sub 470 T=0.794 C=0.206
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 T=0.659 C=0.341
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 T=0.554 C=0.446
HGDP-CEPH-db Supplement 1 Europe Sub 320 T=0.544 C=0.456
HGDP-CEPH-db Supplement 1 Africa Sub 242 T=0.992 C=0.008
HGDP-CEPH-db Supplement 1 America Sub 216 T=0.940 C=0.060
HGDP-CEPH-db Supplement 1 Oceania Sub 72 T=0.49 C=0.51
HapMap Global Study-wide 1892 T=0.7960 C=0.2040
HapMap American Sub 770 T=0.739 C=0.261
HapMap African Sub 692 T=0.906 C=0.094
HapMap Asian Sub 254 T=0.823 C=0.177
HapMap Europe Sub 176 T=0.574 C=0.426
SGDP_PRJ Global Study-wide 178 T=0.174 C=0.826
Qatari Global Study-wide 108 T=0.639 C=0.361
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 48 T=0.62 C=0.38
A Vietnamese Genetic Variation Database Global Study-wide 47 T=0.87 C=0.13
The Danish reference pan genome Danish Study-wide 40 T=0.60 C=0.40
Siberian Global Study-wide 18 T=0.28 C=0.72
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr X NC_000023.11:g.49252667T>C
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1492096T>C
CCDC22 RefSeqGene NG_021311.2:g.22203T>C
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.17161A>G
GRCh37.p13 chr X NC_000023.10:g.49109128T>C
Gene: FOXP3, forkhead box P3 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
FOXP3 transcript variant 2 NM_001114377.2:c.939+459A…

NM_001114377.2:c.939+459A>G

N/A Intron Variant
FOXP3 transcript variant 1 NM_014009.4:c.1044+459A>G N/A Intron Variant
FOXP3 transcript variant X1 XM_006724533.2:c.1113+459…

XM_006724533.2:c.1113+459A>G

N/A Intron Variant
FOXP3 transcript variant X2 XM_017029567.1:c.990+459A…

XM_017029567.1:c.990+459A>G

N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement T= C
GRCh38.p13 chr X NC_000023.11:g.49252667= NC_000023.11:g.49252667T>C
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1492096= NW_004070880.2:g.1492096T>C
CCDC22 RefSeqGene NG_021311.2:g.22203= NG_021311.2:g.22203T>C
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.17161= NG_007392.1:g.17161A>G
GRCh37.p13 chr X NC_000023.10:g.49109128= NC_000023.10:g.49109128T>C
FOXP3 transcript variant 2 NM_001114377.1:c.939+459= NM_001114377.1:c.939+459A>G
FOXP3 transcript variant 2 NM_001114377.2:c.939+459= NM_001114377.2:c.939+459A>G
FOXP3 transcript variant 1 NM_014009.3:c.1044+459= NM_014009.3:c.1044+459A>G
FOXP3 transcript variant 1 NM_014009.4:c.1044+459= NM_014009.4:c.1044+459A>G
FOXP3 transcript variant X1 XM_005272610.1:c.1368+459= XM_005272610.1:c.1368+459A>G
FOXP3 transcript variant X2 XM_005272611.1:c.1263+459= XM_005272611.1:c.1263+459A>G
FOXP3 transcript variant X3 XM_005272612.1:c.894+459= XM_005272612.1:c.894+459A>G
FOXP3 transcript variant X1 XM_005278037.1:c.894+459= XM_005278037.1:c.894+459A>G
FOXP3 transcript variant X1 XM_006724533.2:c.1113+459= XM_006724533.2:c.1113+459A>G
FOXP3 transcript variant X2 XM_017029567.1:c.990+459= XM_017029567.1:c.990+459A>G
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

95 SubSNP, 16 Frequency submissions
No Submitter Submission ID Date (Build)
1 YUSUKE ss3219175 Sep 28, 2001 (100)
2 IIPGA-WEISS-MARTINEZ ss15355300 Feb 27, 2004 (120)
3 CSHL-HAPMAP ss17298112 Feb 27, 2004 (120)
4 SSAHASNP ss21020292 Apr 05, 2004 (121)
5 PERLEGEN ss24729813 Sep 20, 2004 (123)
6 ILLUMINA ss66612524 Nov 29, 2006 (127)
7 ILLUMINA ss67241434 Nov 29, 2006 (127)
8 ILLUMINA ss67638154 Nov 29, 2006 (127)
9 ILLUMINA ss70719783 May 25, 2008 (130)
10 ILLUMINA ss71288084 May 16, 2007 (127)
11 ILLUMINA ss75436228 Dec 06, 2007 (129)
12 HGSV ss78286392 Dec 06, 2007 (129)
13 ILLUMINA ss79126000 Dec 15, 2007 (130)
14 KRIBB_YJKIM ss84019231 Dec 15, 2007 (130)
15 1000GENOMES ss112882524 Jan 25, 2009 (130)
16 ILLUMINA ss121982193 Dec 01, 2009 (131)
17 ILLUMINA ss153898558 Dec 01, 2009 (131)
18 GMI ss157468859 Dec 01, 2009 (131)
19 ILLUMINA ss159376400 Dec 01, 2009 (131)
20 ILLUMINA ss160527858 Dec 01, 2009 (131)
21 ENSEMBL ss161795536 Dec 01, 2009 (131)
22 ILLUMINA ss171154003 Jul 04, 2010 (132)
23 ILLUMINA ss173245583 Jul 04, 2010 (132)
24 BCM-HGSC-SUB ss208902579 Jul 04, 2010 (132)
25 BL ss255994879 May 09, 2011 (134)
26 GMI ss283749156 May 04, 2012 (137)
27 PJP ss294449648 May 09, 2011 (134)
28 1000GENOMES ss341475221 May 09, 2011 (134)
29 ILLUMINA ss480504494 May 04, 2012 (137)
30 ILLUMINA ss480518814 May 04, 2012 (137)
31 ILLUMINA ss481325796 Sep 11, 2015 (146)
32 ILLUMINA ss485049704 May 04, 2012 (137)
33 ILLUMINA ss537068636 Sep 11, 2015 (146)
34 TISHKOFF ss566863653 Apr 25, 2013 (138)
35 SSMP ss662799222 Apr 25, 2013 (138)
36 ILLUMINA ss779038613 Apr 09, 2015 (144)
37 ILLUMINA ss782971069 Apr 09, 2015 (144)
38 ILLUMINA ss783932601 Apr 09, 2015 (144)
39 ILLUMINA ss825456518 Apr 01, 2015 (144)
40 ILLUMINA ss832227400 Apr 09, 2015 (144)
41 ILLUMINA ss832888203 Apr 09, 2015 (144)
42 ILLUMINA ss833479033 Apr 09, 2015 (144)
43 ILLUMINA ss834501420 Apr 09, 2015 (144)
44 JMKIDD_LAB ss1082911153 Apr 09, 2015 (144)
45 DDI ss1432040964 Apr 09, 2015 (144)
46 1000GENOMES ss1554366484 Apr 09, 2015 (144)
47 EVA_GENOME_DK ss1583389262 Apr 09, 2015 (144)
48 EVA_UK10K_ALSPAC ss1640734698 Apr 09, 2015 (144)
49 EVA_UK10K_TWINSUK ss1683728731 Apr 09, 2015 (144)
50 ILLUMINA ss1752808326 Sep 11, 2015 (146)
51 WEILL_CORNELL_DGM ss1939333597 Feb 17, 2016 (147)
52 ILLUMINA ss1945973014 Feb 17, 2016 (147)
53 USC_VALOUEV ss2159049297 Oct 13, 2018 (152)
54 HUMAN_LONGEVITY ss2317255263 Dec 20, 2016 (150)
55 SYSTEMSBIOZJU ss2629701927 Oct 13, 2018 (152)
56 ILLUMINA ss2634959955 Oct 13, 2018 (152)
57 ILLUMINA ss2635202344 Nov 08, 2017 (151)
58 GRF ss2710169688 Oct 13, 2018 (152)
59 GNOMAD ss2978643497 Oct 13, 2018 (152)
60 SWEGEN ss3019943336 Oct 13, 2018 (152)
61 ILLUMINA ss3023007273 Oct 13, 2018 (152)
62 BIOINF_KMB_FNS_UNIBA ss3029047068 Nov 08, 2017 (151)
63 TOPMED ss3610482646 Nov 08, 2017 (151)
64 ILLUMINA ss3630431423 Oct 13, 2018 (152)
65 ILLUMINA ss3632846185 Oct 13, 2018 (152)
66 ILLUMINA ss3633558745 Oct 13, 2018 (152)
67 ILLUMINA ss3634288522 Oct 13, 2018 (152)
68 ILLUMINA ss3635249073 Oct 13, 2018 (152)
69 ILLUMINA ss3636997527 Oct 13, 2018 (152)
70 ILLUMINA ss3637719331 Oct 13, 2018 (152)
71 ILLUMINA ss3638858270 Oct 13, 2018 (152)
72 ILLUMINA ss3639432386 Oct 13, 2018 (152)
73 ILLUMINA ss3639751487 Oct 13, 2018 (152)
74 ILLUMINA ss3640956556 Oct 13, 2018 (152)
75 ILLUMINA ss3641255840 Oct 13, 2018 (152)
76 ILLUMINA ss3641553753 Oct 13, 2018 (152)
77 ILLUMINA ss3643782533 Oct 13, 2018 (152)
78 ILLUMINA ss3653565706 Oct 13, 2018 (152)
79 ILLUMINA ss3726677674 Jul 13, 2019 (153)
80 ILLUMINA ss3744330177 Jul 13, 2019 (153)
81 ILLUMINA ss3745549489 Jul 13, 2019 (153)
82 EVA ss3770148712 Jul 13, 2019 (153)
83 ILLUMINA ss3773041186 Jul 13, 2019 (153)
84 KHV_HUMAN_GENOMES ss3822976704 Jul 13, 2019 (153)
85 EVA ss3836168097 Apr 27, 2020 (154)
86 EVA ss3841695915 Apr 27, 2020 (154)
87 EVA ss3847216125 Apr 27, 2020 (154)
88 HGDP ss3847973131 Apr 27, 2020 (154)
89 SGDP_PRJ ss3891402662 Apr 27, 2020 (154)
90 KRGDB ss3941825770 Apr 27, 2020 (154)
91 EVA ss3984765727 Apr 27, 2021 (155)
92 EVA ss3985943497 Apr 27, 2021 (155)
93 GNOMAD ss4371253486 Apr 27, 2021 (155)
94 TOPMED ss5122284279 Apr 27, 2021 (155)
95 TOMMO_GENOMICS ss5234393438 Apr 27, 2021 (155)
96 1000Genomes NC_000023.10 - 49109128 Oct 13, 2018 (152)
97 The Avon Longitudinal Study of Parents and Children NC_000023.10 - 49109128 Oct 13, 2018 (152)
98 The Danish reference pan genome NC_000023.10 - 49109128 Apr 27, 2020 (154)
99 gnomAD - Genomes NC_000023.11 - 49252667 Apr 27, 2021 (155)
100 HGDP-CEPH-db Supplement 1 NC_000023.9 - 48996072 Apr 27, 2020 (154)
101 HapMap NC_000023.11 - 49252667 Apr 27, 2020 (154)
102 KOREAN population from KRGDB NC_000023.10 - 49109128 Apr 27, 2020 (154)
103 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000023.10 - 49109128 Apr 27, 2021 (155)
104 Qatari NC_000023.10 - 49109128 Apr 27, 2020 (154)
105 SGDP_PRJ NC_000023.10 - 49109128 Apr 27, 2020 (154)
106 Siberian NC_000023.10 - 49109128 Apr 27, 2020 (154)
107 8.3KJPN NC_000023.10 - 49109128 Apr 27, 2021 (155)
108 TopMed NC_000023.11 - 49252667 Apr 27, 2021 (155)
109 UK 10K study - Twins NC_000023.10 - 49109128 Oct 13, 2018 (152)
110 A Vietnamese Genetic Variation Database NC_000023.10 - 49109128 Jul 13, 2019 (153)
111 ALFA NC_000023.11 - 49252667 Apr 27, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs17328056 Oct 07, 2004 (123)
rs59241800 May 25, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
ss78286392, ss3639432386, ss3639751487 NC_000023.8:48865498:T:C NC_000023.11:49252666:T:C (self)
651023, ss112882524, ss160527858, ss208902579, ss255994879, ss283749156, ss294449648, ss480504494, ss825456518, ss2635202344, ss3643782533, ss3847973131 NC_000023.9:48996071:T:C NC_000023.11:49252666:T:C (self)
82342058, 45463614, 9554199, 49003164, 1169424, 21375519, 43419642, 11565651, 92362745, 45463614, 10018685, ss341475221, ss480518814, ss481325796, ss485049704, ss537068636, ss566863653, ss662799222, ss779038613, ss782971069, ss783932601, ss832227400, ss832888203, ss833479033, ss834501420, ss1082911153, ss1432040964, ss1554366484, ss1583389262, ss1640734698, ss1683728731, ss1752808326, ss1939333597, ss1945973014, ss2159049297, ss2629701927, ss2634959955, ss2710169688, ss2978643497, ss3019943336, ss3023007273, ss3630431423, ss3632846185, ss3633558745, ss3634288522, ss3635249073, ss3636997527, ss3637719331, ss3638858270, ss3640956556, ss3641255840, ss3641553753, ss3653565706, ss3744330177, ss3745549489, ss3770148712, ss3773041186, ss3836168097, ss3841695915, ss3891402662, ss3941825770, ss3984765727, ss3985943497, ss5234393438 NC_000023.10:49109127:T:C NC_000023.11:49252666:T:C (self)
580283979, 3982123, 428122717, 685890636, 3238414271, ss2317255263, ss3029047068, ss3610482646, ss3726677674, ss3822976704, ss3847216125, ss4371253486, ss5122284279 NC_000023.11:49252666:T:C NC_000023.11:49252666:T:C (self)
ss17298112, ss21020292 NT_011568.13:5498769:T:C NC_000023.11:49252666:T:C (self)
ss3219175, ss15355300, ss24729813, ss66612524, ss67241434, ss67638154, ss70719783, ss71288084, ss75436228, ss79126000, ss84019231, ss121982193, ss153898558, ss157468859, ss159376400, ss161795536, ss171154003, ss173245583 NT_079573.4:11960871:T:C NC_000023.11:49252666:T:C (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

15 citations for rs2280883
PMID Title Author Year Journal
17526924 SNPs in the FOXP3 gene region show no association with Juvenile Idiopathic Arthritis in a UK Caucasian population. Eastell T et al. 2007 Rheumatology (Oxford, England)
19141582 Autoimmune thyroiditis and diabetes: dissecting the joint genetic susceptibility in a large cohort of multiplex families. Villano MJ et al. 2009 The Journal of clinical endocrinology and metabolism
21481380 Analysis of FOXP3 polymorphisms in infertile women with and without endometriosis. André GM et al. 2011 Fertility and sterility
27014188 Dissecting the Genetic Susceptibility to Graves' Disease in a Cohort of Patients of Italian Origin. Lombardi A et al. 2016 Frontiers in endocrinology
27747372 FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. Wu Z et al. 2017 European journal of clinical pharmacology
27892628 Association between FOXP3 gene polymorphisms and risk of differentiated thyroid cancer in Chinese Han population. Jiang W et al. 2017 Journal of clinical laboratory analysis
28508461 FOXP3 polymorphisms in interstitial lung disease among Chinese Han population: A genetic association study. Yao J et al. 2018 The clinical respiratory journal
28643491 Association of Foxp3 Polymorphism With Allograft Outcome in Kidney Transplantation. Park H et al. 2017 Annals of laboratory medicine
29101067 FOXP3 rs3761549 polymorphism predicts long-term renal allograft function in patients receiving cyclosporine-based immunosuppressive regimen. Xu QX et al. 2018 Gene
30027704 Association of FOXP3 Single Nucleotide Polymorphisms With Clinical Outcomes After Allogenic Hematopoietic Stem Cell Transplantation. Nam M et al. 2018 Annals of laboratory medicine
30142808 Functional Foxp3 polymorphisms and the susceptibility to cancer: An update meta-analysis. Cheng Z et al. 2018 Medicine
30782783 The association of <i>FOXP3</i> gene polymorphisms with cancer susceptibility: a comprehensive systemic review and meta-analysis. Chen Y et al. 2019 Bioscience reports
30875252 Association of Foxp3 and TGF-β1 Polymorphisms with Pre-Eclampsia Risk in Chinese Women. Chen J et al. 2019 Genetic testing and molecular biomarkers
31987907 FOXP3 rs2280883 polymorphism confers susceptibility to colorectal cancer in a Chinese Han population. Lou Y et al. 2020 Gene
32545568 CTLA-4 Expression Plays a Role in PSC and PBC Progression. Meister P et al. 2020 Diseases (Basel, Switzerland)
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post676+237644a