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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2242592

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chr11:113408708 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
G>A
Variation Type
SNV Single Nucleotide Variation
Frequency
G=0.439873 (116430/264690, TOPMED)
G=0.317650 (63523/199978, ALFA)
G=0.432716 (60537/139900, GnomAD) (+ 17 more)
A=0.43114 (7225/16758, 8.3KJPN)
G=0.4958 (2483/5008, 1000G)
G=0.2993 (1341/4480, Estonian)
G=0.2963 (1142/3854, ALSPAC)
G=0.2967 (1100/3708, TWINSUK)
A=0.4683 (1372/2930, KOREAN)
G=0.4837 (1007/2082, HGDP_Stanford)
A=0.4349 (821/1888, HapMap)
G=0.304 (303/998, GoNL)
A=0.481 (380/790, PRJEB37584)
G=0.297 (178/600, NorthernSweden)
G=0.294 (121/412, SGDP_PRJ)
A=0.435 (94/216, Qatari)
A=0.458 (98/214, Vietnamese)
G=0.32 (14/44, Siberian)
G=0.30 (12/40, GENOME_DK)
G=0.23 (6/26, Ancient Sardinia)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
None
Publications
18 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 199978 G=0.317650 A=0.682350
European Sub 172746 G=0.297408 A=0.702592
African Sub 7094 G=0.6763 A=0.3237
African Others Sub 264 G=0.723 A=0.277
African American Sub 6830 G=0.6745 A=0.3255
Asian Sub 702 G=0.538 A=0.462
East Asian Sub 556 G=0.538 A=0.462
Other Asian Sub 146 G=0.541 A=0.459
Latin American 1 Sub 844 G=0.461 A=0.539
Latin American 2 Sub 6904 G=0.3317 A=0.6683
South Asian Sub 5042 G=0.3667 A=0.6333
Other Sub 6646 G=0.3676 A=0.6324


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 G=0.439873 A=0.560127
Allele Frequency Aggregator Total Global 199978 G=0.317650 A=0.682350
Allele Frequency Aggregator European Sub 172746 G=0.297408 A=0.702592
Allele Frequency Aggregator African Sub 7094 G=0.6763 A=0.3237
Allele Frequency Aggregator Latin American 2 Sub 6904 G=0.3317 A=0.6683
Allele Frequency Aggregator Other Sub 6646 G=0.3676 A=0.6324
Allele Frequency Aggregator South Asian Sub 5042 G=0.3667 A=0.6333
Allele Frequency Aggregator Latin American 1 Sub 844 G=0.461 A=0.539
Allele Frequency Aggregator Asian Sub 702 G=0.538 A=0.462
gnomAD - Genomes Global Study-wide 139900 G=0.432716 A=0.567284
gnomAD - Genomes European Sub 75798 G=0.30659 A=0.69341
gnomAD - Genomes African Sub 41892 G=0.67533 A=0.32467
gnomAD - Genomes American Sub 13624 G=0.38895 A=0.61105
gnomAD - Genomes Ashkenazi Jewish Sub 3322 G=0.3438 A=0.6562
gnomAD - Genomes East Asian Sub 3122 G=0.5400 A=0.4600
gnomAD - Genomes Other Sub 2142 G=0.4108 A=0.5892
8.3KJPN JAPANESE Study-wide 16758 G=0.56886 A=0.43114
1000Genomes Global Study-wide 5008 G=0.4958 A=0.5042
1000Genomes African Sub 1322 G=0.7216 A=0.2784
1000Genomes East Asian Sub 1008 G=0.5327 A=0.4673
1000Genomes Europe Sub 1006 G=0.3072 A=0.6928
1000Genomes South Asian Sub 978 G=0.412 A=0.588
1000Genomes American Sub 694 G=0.403 A=0.597
Genetic variation in the Estonian population Estonian Study-wide 4480 G=0.2993 A=0.7007
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 G=0.2963 A=0.7037
UK 10K study - Twins TWIN COHORT Study-wide 3708 G=0.2967 A=0.7033
KOREAN population from KRGDB KOREAN Study-wide 2930 G=0.5317 A=0.4683
HGDP-CEPH-db Supplement 1 Global Study-wide 2082 G=0.4837 A=0.5163
HGDP-CEPH-db Supplement 1 Est_Asia Sub 468 G=0.553 A=0.447
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 G=0.461 A=0.539
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 G=0.400 A=0.600
HGDP-CEPH-db Supplement 1 Europe Sub 320 G=0.281 A=0.719
HGDP-CEPH-db Supplement 1 Africa Sub 242 G=0.798 A=0.202
HGDP-CEPH-db Supplement 1 America Sub 216 G=0.389 A=0.611
HGDP-CEPH-db Supplement 1 Oceania Sub 72 G=0.69 A=0.31
HapMap Global Study-wide 1888 G=0.5651 A=0.4349
HapMap American Sub 768 G=0.427 A=0.573
HapMap African Sub 690 G=0.799 A=0.201
HapMap Asian Sub 254 G=0.555 A=0.445
HapMap Europe Sub 176 G=0.267 A=0.733
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 G=0.304 A=0.696
CNV burdens in cranial meningiomas Global Study-wide 790 G=0.519 A=0.481
CNV burdens in cranial meningiomas CRM Sub 790 G=0.519 A=0.481
Northern Sweden ACPOP Study-wide 600 G=0.297 A=0.703
SGDP_PRJ Global Study-wide 412 G=0.294 A=0.706
Qatari Global Study-wide 216 G=0.565 A=0.435
A Vietnamese Genetic Variation Database Global Study-wide 214 G=0.542 A=0.458
Siberian Global Study-wide 44 G=0.32 A=0.68
The Danish reference pan genome Danish Study-wide 40 G=0.30 A=0.70
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 26 G=0.23 A=0.77
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr 11 NC_000011.10:g.113408708G>A
GRCh37.p13 chr 11 NC_000011.9:g.113279430G>A
DRD2 RefSeqGene NG_008841.1:g.71572C>T
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement G= A
GRCh38.p13 chr 11 NC_000011.10:g.113408708= NC_000011.10:g.113408708G>A
GRCh37.p13 chr 11 NC_000011.9:g.113279430= NC_000011.9:g.113279430G>A
DRD2 RefSeqGene NG_008841.1:g.71572= NG_008841.1:g.71572C>T
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

114 SubSNP, 20 Frequency submissions
No Submitter Submission ID Date (Build)
1 YUSUKE ss3198965 Aug 15, 2001 (98)
2 SC_JCM ss3860745 Sep 28, 2001 (100)
3 SC_SNP ss15908245 Feb 27, 2004 (120)
4 PERLEGEN ss24090087 Sep 20, 2004 (123)
5 ABI ss38717408 Mar 14, 2006 (126)
6 ILLUMINA ss66556443 Dec 01, 2006 (127)
7 ILLUMINA ss67237140 Dec 01, 2006 (127)
8 ILLUMINA ss67633395 Dec 01, 2006 (127)
9 PERLEGEN ss69329208 May 18, 2007 (127)
10 ILLUMINA ss70715467 May 26, 2008 (130)
11 ILLUMINA ss71283305 May 18, 2007 (127)
12 ILLUMINA ss75615338 Dec 07, 2007 (129)
13 ILLUMINA ss79122890 Dec 15, 2007 (130)
14 HGSV ss83121756 Dec 15, 2007 (130)
15 KRIBB_YJKIM ss84006642 Dec 15, 2007 (130)
16 BCMHGSC_JDW ss88801197 Mar 24, 2008 (129)
17 HUMANGENOME_JCVI ss97418980 Feb 06, 2009 (130)
18 BGI ss103002125 Dec 01, 2009 (131)
19 1000GENOMES ss111100608 Jan 25, 2009 (130)
20 ILLUMINA ss121964011 Dec 01, 2009 (131)
21 ENSEMBL ss132838693 Dec 01, 2009 (131)
22 ENSEMBL ss137852154 Dec 01, 2009 (131)
23 ILLUMINA ss153892727 Dec 01, 2009 (131)
24 ILLUMINA ss159371791 Dec 01, 2009 (131)
25 ILLUMINA ss160520624 Dec 01, 2009 (131)
26 COMPLETE_GENOMICS ss168755770 Jul 04, 2010 (132)
27 ILLUMINA ss171117887 Jul 04, 2010 (132)
28 ILLUMINA ss173209223 Jul 04, 2010 (132)
29 COMPLETE_GENOMICS ss175282646 Jul 04, 2010 (132)
30 BUSHMAN ss203228006 Jul 04, 2010 (132)
31 BCM-HGSC-SUB ss207630096 Jul 04, 2010 (132)
32 1000GENOMES ss225469615 Jul 14, 2010 (132)
33 1000GENOMES ss235724770 Jul 15, 2010 (132)
34 1000GENOMES ss242321857 Jul 15, 2010 (132)
35 BL ss255384345 May 09, 2011 (134)
36 GMI ss281176554 May 04, 2012 (137)
37 GMI ss286460491 Apr 25, 2013 (138)
38 PJP ss291142841 May 09, 2011 (134)
39 ILLUMINA ss480481751 May 04, 2012 (137)
40 ILLUMINA ss480496120 May 04, 2012 (137)
41 ILLUMINA ss481296819 Sep 08, 2015 (146)
42 ILLUMINA ss485038363 May 04, 2012 (137)
43 ILLUMINA ss537060782 Sep 08, 2015 (146)
44 TISHKOFF ss562835364 Apr 25, 2013 (138)
45 SSMP ss658358406 Apr 25, 2013 (138)
46 ILLUMINA ss778487287 Sep 08, 2015 (146)
47 ILLUMINA ss782965421 Sep 08, 2015 (146)
48 ILLUMINA ss783927247 Sep 08, 2015 (146)
49 ILLUMINA ss825453408 Apr 01, 2015 (144)
50 ILLUMINA ss832221690 Sep 08, 2015 (146)
51 ILLUMINA ss832883612 Jul 13, 2019 (153)
52 ILLUMINA ss833943239 Sep 08, 2015 (146)
53 EVA-GONL ss988978318 Aug 21, 2014 (142)
54 JMKIDD_LAB ss1078056526 Aug 21, 2014 (142)
55 1000GENOMES ss1343024539 Aug 21, 2014 (142)
56 DDI ss1426765542 Apr 01, 2015 (144)
57 EVA_GENOME_DK ss1575961543 Apr 01, 2015 (144)
58 EVA_DECODE ss1598644333 Apr 01, 2015 (144)
59 EVA_UK10K_ALSPAC ss1627494311 Apr 01, 2015 (144)
60 EVA_UK10K_TWINSUK ss1670488344 Apr 01, 2015 (144)
61 EVA_SVP ss1713285862 Apr 01, 2015 (144)
62 ILLUMINA ss1751995132 Sep 08, 2015 (146)
63 WEILL_CORNELL_DGM ss1932339460 Feb 12, 2016 (147)
64 GENOMED ss1967462509 Jul 19, 2016 (147)
65 JJLAB ss2026913630 Sep 14, 2016 (149)
66 USC_VALOUEV ss2155226164 Dec 20, 2016 (150)
67 HUMAN_LONGEVITY ss2185829175 Dec 20, 2016 (150)
68 TOPMED ss2349419642 Dec 20, 2016 (150)
69 SYSTEMSBIOZJU ss2627931645 Nov 08, 2017 (151)
70 ILLUMINA ss2632889062 Nov 08, 2017 (151)
71 GRF ss2699536326 Nov 08, 2017 (151)
72 GNOMAD ss2904624005 Nov 08, 2017 (151)
73 AFFY ss2985599036 Nov 08, 2017 (151)
74 SWEGEN ss3008803592 Nov 08, 2017 (151)
75 BIOINF_KMB_FNS_UNIBA ss3027257484 Nov 08, 2017 (151)
76 TOPMED ss3156776897 Nov 08, 2017 (151)
77 CSHL ss3349801585 Nov 08, 2017 (151)
78 ILLUMINA ss3626753128 Oct 12, 2018 (152)
79 ILLUMINA ss3630902933 Oct 12, 2018 (152)
80 ILLUMINA ss3632999858 Oct 12, 2018 (152)
81 ILLUMINA ss3633699831 Oct 12, 2018 (152)
82 ILLUMINA ss3634475975 Oct 12, 2018 (152)
83 ILLUMINA ss3635391106 Oct 12, 2018 (152)
84 ILLUMINA ss3636160269 Oct 12, 2018 (152)
85 ILLUMINA ss3637142009 Oct 12, 2018 (152)
86 ILLUMINA ss3637931196 Oct 12, 2018 (152)
87 ILLUMINA ss3638979292 Oct 12, 2018 (152)
88 ILLUMINA ss3639490895 Oct 12, 2018 (152)
89 ILLUMINA ss3640183311 Oct 12, 2018 (152)
90 ILLUMINA ss3641021033 Oct 12, 2018 (152)
91 ILLUMINA ss3641315571 Oct 12, 2018 (152)
92 ILLUMINA ss3642927606 Oct 12, 2018 (152)
93 URBANLAB ss3649708326 Oct 12, 2018 (152)
94 EGCUT_WGS ss3676131149 Jul 13, 2019 (153)
95 EVA_DECODE ss3692627367 Jul 13, 2019 (153)
96 ACPOP ss3738552514 Jul 13, 2019 (153)
97 ILLUMINA ss3744776751 Jul 13, 2019 (153)
98 EVA ss3749830106 Jul 13, 2019 (153)
99 ILLUMINA ss3772276516 Jul 13, 2019 (153)
100 PACBIO ss3787071695 Jul 13, 2019 (153)
101 PACBIO ss3792195267 Jul 13, 2019 (153)
102 PACBIO ss3797077788 Jul 13, 2019 (153)
103 KHV_HUMAN_GENOMES ss3815160403 Jul 13, 2019 (153)
104 EVA ss3832846137 Apr 26, 2020 (154)
105 EVA ss3839985411 Apr 26, 2020 (154)
106 EVA ss3845467125 Apr 26, 2020 (154)
107 HGDP ss3847431837 Apr 26, 2020 (154)
108 SGDP_PRJ ss3877167351 Apr 26, 2020 (154)
109 KRGDB ss3925625399 Apr 26, 2020 (154)
110 EVA ss3984657504 Apr 26, 2021 (155)
111 EVA ss3985557884 Apr 26, 2021 (155)
112 EVA ss4017559753 Apr 26, 2021 (155)
113 TOPMED ss4900495263 Apr 26, 2021 (155)
114 TOMMO_GENOMICS ss5203954889 Apr 26, 2021 (155)
115 1000Genomes NC_000011.9 - 113279430 Oct 12, 2018 (152)
116 The Avon Longitudinal Study of Parents and Children NC_000011.9 - 113279430 Oct 12, 2018 (152)
117 Genetic variation in the Estonian population NC_000011.9 - 113279430 Oct 12, 2018 (152)
118 The Danish reference pan genome NC_000011.9 - 113279430 Apr 26, 2020 (154)
119 gnomAD - Genomes NC_000011.10 - 113408708 Apr 26, 2021 (155)
120 Genome of the Netherlands Release 5 NC_000011.9 - 113279430 Apr 26, 2020 (154)
121 HGDP-CEPH-db Supplement 1 NC_000011.8 - 112784640 Apr 26, 2020 (154)
122 HapMap NC_000011.10 - 113408708 Apr 26, 2020 (154)
123 KOREAN population from KRGDB NC_000011.9 - 113279430 Apr 26, 2020 (154)
124 Northern Sweden NC_000011.9 - 113279430 Jul 13, 2019 (153)
125 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000011.9 - 113279430 Apr 26, 2021 (155)
126 CNV burdens in cranial meningiomas NC_000011.9 - 113279430 Apr 26, 2021 (155)
127 Qatari NC_000011.9 - 113279430 Apr 26, 2020 (154)
128 SGDP_PRJ NC_000011.9 - 113279430 Apr 26, 2020 (154)
129 Siberian NC_000011.9 - 113279430 Apr 26, 2020 (154)
130 8.3KJPN NC_000011.9 - 113279430 Apr 26, 2021 (155)
131 TopMed NC_000011.10 - 113408708 Apr 26, 2021 (155)
132 UK 10K study - Twins NC_000011.9 - 113279430 Oct 12, 2018 (152)
133 A Vietnamese Genetic Variation Database NC_000011.9 - 113279430 Jul 13, 2019 (153)
134 ALFA NC_000011.10 - 113408708 Apr 26, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs60748478 May 26, 2008 (130)
rs386562316 Aug 21, 2014 (142)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
109729, ss83121756, ss88801197, ss111100608, ss168755770, ss175282646, ss203228006, ss207630096, ss255384345, ss281176554, ss286460491, ss291142841, ss480481751, ss825453408, ss1598644333, ss1713285862, ss3638979292, ss3639490895, ss3642927606, ss3847431837 NC_000011.8:112784639:G:A NC_000011.10:113408707:G:A (self)
55608970, 30866786, 21869397, 2741432, 13774910, 32802793, 11837379, 783811, 206989, 14381390, 29184331, 7742518, 61924196, 30866786, 6850647, ss225469615, ss235724770, ss242321857, ss480496120, ss481296819, ss485038363, ss537060782, ss562835364, ss658358406, ss778487287, ss782965421, ss783927247, ss832221690, ss832883612, ss833943239, ss988978318, ss1078056526, ss1343024539, ss1426765542, ss1575961543, ss1627494311, ss1670488344, ss1751995132, ss1932339460, ss1967462509, ss2026913630, ss2155226164, ss2349419642, ss2627931645, ss2632889062, ss2699536326, ss2904624005, ss2985599036, ss3008803592, ss3349801585, ss3626753128, ss3630902933, ss3632999858, ss3633699831, ss3634475975, ss3635391106, ss3636160269, ss3637142009, ss3637931196, ss3640183311, ss3641021033, ss3641315571, ss3676131149, ss3738552514, ss3744776751, ss3749830106, ss3772276516, ss3787071695, ss3792195267, ss3797077788, ss3832846137, ss3839985411, ss3877167351, ss3925625399, ss3984657504, ss3985557884, ss4017559753, ss5203954889 NC_000011.9:113279429:G:A NC_000011.10:113408707:G:A (self)
392391599, 702397, 72748634, 116040919, 7419843408, ss2185829175, ss3027257484, ss3156776897, ss3649708326, ss3692627367, ss3815160403, ss3845467125, ss4900495263 NC_000011.10:113408707:G:A NC_000011.10:113408707:G:A (self)
ss15908245 NT_033899.6:16823215:G:A NC_000011.10:113408707:G:A (self)
ss3198965, ss3860745, ss24090087, ss38717408, ss66556443, ss67237140, ss67633395, ss69329208, ss70715467, ss71283305, ss75615338, ss79122890, ss84006642, ss97418980, ss103002125, ss121964011, ss132838693, ss137852154, ss153892727, ss159371791, ss160520624, ss171117887, ss173209223 NT_033899.8:16841845:G:A NC_000011.10:113408707:G:A (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

18 citations for rs2242592
PMID Title Author Year Journal
18821566 SNPs in dopamine D2 receptor gene (DRD2) and norepinephrine transporter gene (NET) are associated with continuous performance task (CPT) phenotypes in ADHD children and their families. Kollins SH et al. 2008 American journal of medical genetics. Part B, Neuropsychiatric genetics
19197363 A genome-wide investigation of SNPs and CNVs in schizophrenia. Need AC et al. 2009 PLoS genetics
19772578 Two-stage case-control association study of dopamine-related genes and migraine. Corominas R et al. 2009 BMC medical genetics
19968402 Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants. Hamidovic A et al. 2009 Experimental and clinical psychopharmacology
20138949 A genetic schizophrenia-susceptibility region located between the ANKK1 and DRD2 genes. Dubertret C et al. 2010 Progress in neuro-psychopharmacology & biological psychiatry
21168125 TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. Ducci F et al. 2011 Biological psychiatry
21906503 Different phenotypic and genotypic presentations in alcohol dependence: age at onset matters. Chen YC et al. 2011 Journal of studies on alcohol and drugs
22021758 Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort. Nyman ES et al. 2011 BMJ open
22424959 DRD2 polymorphisms modulate reward and emotion processing, dopamine neurotransmission and openness to experience. Peciña M et al. 2013 Cortex; a journal devoted to the study of the nervous system and behavior
22761283 Multigene interactions and the prediction of depression in the Wisconsin Longitudinal Study. Roetker NS et al. 2012 BMJ open
22893251 Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol. Giegling I et al. 2013 European archives of psychiatry and clinical neuroscience
24607704 Ripple effects of developmental disabilities and mental illness on nondisabled adult siblings. Wolfe B et al. 2014 Social science & medicine (1982)
25545355 Genetic variants and early cigarette smoking and nicotine dependence phenotypes in adolescents. O'Loughlin J et al. 2014 PloS one
28085950 Impact of DRD2/ANKK1 and COMT Polymorphisms on Attention and Cognitive Functions in Schizophrenia. Nkam I et al. 2017 PloS one
28744152 Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder. Zastrozhin MS et al. 2017 Pharmacogenomics and personalized medicine
29992684 A systematic review: Candidate gene and environment interaction on alcohol use and misuse among adolescents and young adults. Kim J et al. 2018 The American journal on addictions
30093869 Biological Predictors of Clozapine Response: A Systematic Review. Samanaite R et al. 2018 Frontiers in psychiatry
33524518 Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region. Mestiri S et al. 2021 Gene
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post676+237644a