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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs2232365

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chrX:49259429 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
T>A / T>C / T>G
Variation Type
SNV Single Nucleotide Variation
Frequency
T=0.382138 (101148/264690, TOPMED)
T=0.39425 (8586/21778, ALFA)
C=0.40565 (5209/12841, 8.3KJPN) (+ 11 more)
T=0.4095 (1546/3775, 1000G)
T=0.4124 (1529/3708, TWINSUK)
C=0.3775 (1106/2930, KOREAN)
T=0.4050 (1170/2889, ALSPAC)
T=0.4070 (770/1892, HapMap)
C=0.045 (24/534, MGP)
T=0.109 (37/338, SGDP_PRJ)
T=0.407 (44/108, Qatari)
C=0.46 (22/48, Vietnamese)
T=0.38 (15/40, GENOME_DK)
T=0.27 (6/22, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
FOXP3 : Intron Variant
Publications
47 citations
Genomic View
See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 21778 T=0.39425 C=0.60575
European Sub 15828 T=0.43044 C=0.56956
African Sub 4066 T=0.2164 C=0.7836
African Others Sub 148 T=0.176 C=0.824
African American Sub 3918 T=0.2180 C=0.7820
Asian Sub 124 T=0.621 C=0.379
East Asian Sub 96 T=0.62 C=0.38
Other Asian Sub 28 T=0.61 C=0.39
Latin American 1 Sub 168 T=0.381 C=0.619
Latin American 2 Sub 670 T=0.546 C=0.454
South Asian Sub 98 T=0.44 C=0.56
Other Sub 824 T=0.416 C=0.584


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 T=0.382138 C=0.617862
Allele Frequency Aggregator Total Global 21778 T=0.39425 C=0.60575
Allele Frequency Aggregator European Sub 15828 T=0.43044 C=0.56956
Allele Frequency Aggregator African Sub 4066 T=0.2164 C=0.7836
Allele Frequency Aggregator Other Sub 824 T=0.416 C=0.584
Allele Frequency Aggregator Latin American 2 Sub 670 T=0.546 C=0.454
Allele Frequency Aggregator Latin American 1 Sub 168 T=0.381 C=0.619
Allele Frequency Aggregator Asian Sub 124 T=0.621 C=0.379
Allele Frequency Aggregator South Asian Sub 98 T=0.44 C=0.56
8.3KJPN JAPANESE Study-wide 12841 T=0.59435 C=0.40565
1000Genomes Global Study-wide 3775 T=0.4095 C=0.5905
1000Genomes African Sub 1003 T=0.1874 C=0.8126
1000Genomes Europe Sub 766 T=0.401 C=0.599
1000Genomes East Asian Sub 764 T=0.641 C=0.359
1000Genomes South Asian Sub 718 T=0.383 C=0.617
1000Genomes American Sub 524 T=0.546 C=0.454
UK 10K study - Twins TWIN COHORT Study-wide 3708 T=0.4124 C=0.5876
KOREAN population from KRGDB KOREAN Study-wide 2930 T=0.6225 A=0.0000, C=0.3775
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 2889 T=0.4050 C=0.5950
HapMap Global Study-wide 1892 T=0.4070 C=0.5930
HapMap American Sub 770 T=0.495 C=0.505
HapMap African Sub 692 T=0.218 C=0.782
HapMap Asian Sub 254 T=0.622 C=0.378
HapMap Europe Sub 176 T=0.455 C=0.545
Medical Genome Project healthy controls from Spanish population Spanish controls Study-wide 534 T=0.955 C=0.045
SGDP_PRJ Global Study-wide 338 T=0.109 C=0.888, G=0.003
Qatari Global Study-wide 108 T=0.407 C=0.593
A Vietnamese Genetic Variation Database Global Study-wide 48 T=0.54 C=0.46
The Danish reference pan genome Danish Study-wide 40 T=0.38 C=0.62
Siberian Global Study-wide 22 T=0.27 C=0.73
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr X NC_000023.11:g.49259429T>A
GRCh38.p13 chr X NC_000023.11:g.49259429T>C
GRCh38.p13 chr X NC_000023.11:g.49259429T>G
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1498858T>A
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1498858T>C
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1498858T>G
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.10403A>T
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.10403A>G
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.10403A>C
GRCh37.p13 chr X NC_000023.10:g.49115886T>A
GRCh37.p13 chr X NC_000023.10:g.49115886T>C
GRCh37.p13 chr X NC_000023.10:g.49115886T>G
Gene: FOXP3, forkhead box P3 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
FOXP3 transcript variant 2 NM_001114377.2:c.-22-902A…

NM_001114377.2:c.-22-902A>T

N/A Intron Variant
FOXP3 transcript variant 1 NM_014009.4:c.-22-902A>T N/A Intron Variant
FOXP3 transcript variant X1 XM_006724533.2:c.-22-902A…

XM_006724533.2:c.-22-902A>T

N/A Intron Variant
FOXP3 transcript variant X2 XM_017029567.1:c.30-902A>T N/A Intron Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement T= A C G
GRCh38.p13 chr X NC_000023.11:g.49259429= NC_000023.11:g.49259429T>A NC_000023.11:g.49259429T>C NC_000023.11:g.49259429T>G
GRCh37.p13 chr X fix patch HG1436_HG1432_PATCH NW_004070880.2:g.1498858= NW_004070880.2:g.1498858T>A NW_004070880.2:g.1498858T>C NW_004070880.2:g.1498858T>G
FOXP3 RefSeqGene (LRG_62) NG_007392.1:g.10403= NG_007392.1:g.10403A>T NG_007392.1:g.10403A>G NG_007392.1:g.10403A>C
GRCh37.p13 chr X NC_000023.10:g.49115886= NC_000023.10:g.49115886T>A NC_000023.10:g.49115886T>C NC_000023.10:g.49115886T>G
FOXP3 transcript variant 2 NM_001114377.1:c.-22-902= NM_001114377.1:c.-22-902A>T NM_001114377.1:c.-22-902A>G NM_001114377.1:c.-22-902A>C
FOXP3 transcript variant 2 NM_001114377.2:c.-22-902= NM_001114377.2:c.-22-902A>T NM_001114377.2:c.-22-902A>G NM_001114377.2:c.-22-902A>C
FOXP3 transcript variant 1 NM_014009.3:c.-22-902= NM_014009.3:c.-22-902A>T NM_014009.3:c.-22-902A>G NM_014009.3:c.-22-902A>C
FOXP3 transcript variant 1 NM_014009.4:c.-22-902= NM_014009.4:c.-22-902A>T NM_014009.4:c.-22-902A>G NM_014009.4:c.-22-902A>C
FOXP3 transcript variant X1 XM_005272610.1:c.303-902= XM_005272610.1:c.303-902A>T XM_005272610.1:c.303-902A>G XM_005272610.1:c.303-902A>C
FOXP3 transcript variant X2 XM_005272611.1:c.303-902= XM_005272611.1:c.303-902A>T XM_005272611.1:c.303-902A>G XM_005272611.1:c.303-902A>C
FOXP3 transcript variant X1 XM_006724533.2:c.-22-902= XM_006724533.2:c.-22-902A>T XM_006724533.2:c.-22-902A>G XM_006724533.2:c.-22-902A>C
FOXP3 transcript variant X2 XM_017029567.1:c.30-902= XM_017029567.1:c.30-902A>T XM_017029567.1:c.30-902A>G XM_017029567.1:c.30-902A>C
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

62 SubSNP, 14 Frequency submissions
No Submitter Submission ID Date (Build)
1 GENAISSANCE ss3179677 Aug 15, 2001 (98)
2 CSHL-HAPMAP ss17290902 Feb 27, 2004 (120)
3 SSAHASNP ss21025426 Apr 05, 2004 (123)
4 ABI ss43585179 Mar 15, 2006 (126)
5 SI_EXO ss61709536 Oct 16, 2006 (127)
6 ILLUMINA ss74995501 Dec 06, 2007 (129)
7 HGSV ss83511396 Dec 15, 2007 (130)
8 HGSV ss85612118 Dec 15, 2007 (130)
9 HGSV ss85773788 Dec 15, 2007 (130)
10 BGI ss105731537 Feb 05, 2009 (130)
11 1000GENOMES ss112882533 Jan 25, 2009 (130)
12 1000GENOMES ss114698373 Jan 25, 2009 (130)
13 ILLUMINA-UK ss115613764 Feb 05, 2009 (130)
14 KRIBB_YJKIM ss119422462 Dec 01, 2009 (131)
15 ENSEMBL ss133967201 Dec 01, 2009 (131)
16 GMI ss157468873 Dec 01, 2009 (131)
17 COMPLETE_GENOMICS ss164894611 Jul 04, 2010 (132)
18 ILLUMINA ss173196090 Jul 04, 2010 (132)
19 BUSHMAN ss204234037 Jul 04, 2010 (132)
20 BCM-HGSC-SUB ss208903867 Jul 04, 2010 (132)
21 BL ss255994886 May 09, 2011 (134)
22 GMI ss283749161 May 04, 2012 (137)
23 PJP ss294449649 May 09, 2011 (134)
24 1000GENOMES ss341475238 May 09, 2011 (134)
25 ILLUMINA ss537058048 Sep 11, 2015 (146)
26 TISHKOFF ss566863659 Apr 25, 2013 (138)
27 SSMP ss662799226 Apr 25, 2013 (138)
28 JMKIDD_LAB ss1082911165 Apr 09, 2015 (144)
29 DDI ss1432040966 Apr 09, 2015 (144)
30 1000GENOMES ss1554366614 Apr 09, 2015 (144)
31 EVA_GENOME_DK ss1583389266 Apr 09, 2015 (144)
32 EVA_UK10K_ALSPAC ss1640734753 Apr 09, 2015 (144)
33 EVA_UK10K_TWINSUK ss1683728786 Apr 09, 2015 (144)
34 EVA_MGP ss1711581759 Apr 09, 2015 (144)
35 WEILL_CORNELL_DGM ss1939333615 Feb 17, 2016 (147)
36 GENOMED ss1971376301 Sep 28, 2016 (149)
37 USC_VALOUEV ss2159049306 Oct 13, 2018 (152)
38 HUMAN_LONGEVITY ss2317255513 Dec 20, 2016 (150)
39 SYSTEMSBIOZJU ss2629701929 Oct 13, 2018 (152)
40 GRF ss2710169700 Oct 13, 2018 (152)
41 GNOMAD ss2978643862 Oct 13, 2018 (152)
42 SWEGEN ss3019943371 Oct 13, 2018 (152)
43 BIOINF_KMB_FNS_UNIBA ss3029047071 Nov 08, 2017 (151)
44 TOPMED ss3610483482 Nov 08, 2017 (151)
45 ILLUMINA ss3630431435 Oct 13, 2018 (152)
46 ILLUMINA ss3638858277 Oct 13, 2018 (152)
47 ILLUMINA ss3641255844 Oct 13, 2018 (152)
48 ILLUMINA ss3643782540 Oct 13, 2018 (152)
49 URBANLAB ss3651273069 Oct 13, 2018 (152)
50 EVA ss3770148758 Jul 13, 2019 (153)
51 PACBIO ss3788898322 Jul 13, 2019 (153)
52 PACBIO ss3793762871 Jul 13, 2019 (153)
53 PACBIO ss3798647977 Jul 13, 2019 (153)
54 KHV_HUMAN_GENOMES ss3822976724 Jul 13, 2019 (153)
55 EVA ss3836168103 Apr 27, 2020 (154)
56 EVA ss3841695917 Apr 27, 2020 (154)
57 EVA ss3847216128 Apr 27, 2020 (154)
58 SGDP_PRJ ss3891402722 Apr 27, 2020 (154)
59 KRGDB ss3941825854 Apr 27, 2020 (154)
60 EVA ss3984765729 Apr 27, 2021 (155)
61 TOPMED ss5122285363 Apr 27, 2021 (155)
62 TOMMO_GENOMICS ss5234393592 Apr 27, 2021 (155)
63 1000Genomes NC_000023.10 - 49115886 Oct 13, 2018 (152)
64 The Avon Longitudinal Study of Parents and Children NC_000023.10 - 49115886 Oct 13, 2018 (152)
65 The Danish reference pan genome NC_000023.10 - 49115886 Apr 27, 2020 (154)
66 HapMap NC_000023.11 - 49259429 Apr 27, 2020 (154)
67 KOREAN population from KRGDB NC_000023.10 - 49115886 Apr 27, 2020 (154)
68 Medical Genome Project healthy controls from Spanish population NC_000023.10 - 49115886 Apr 27, 2020 (154)
69 Qatari NC_000023.10 - 49115886 Apr 27, 2020 (154)
70 SGDP_PRJ NC_000023.10 - 49115886 Apr 27, 2020 (154)
71 Siberian NC_000023.10 - 49115886 Apr 27, 2020 (154)
72 8.3KJPN NC_000023.10 - 49115886 Apr 27, 2021 (155)
73 TopMed NC_000023.11 - 49259429 Apr 27, 2021 (155)
74 UK 10K study - Twins NC_000023.10 - 49115886 Oct 13, 2018 (152)
75 A Vietnamese Genetic Variation Database NC_000023.10 - 49115886 Jul 13, 2019 (153)
76 ALFA NC_000023.11 - 49259429 Apr 27, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs12849847 Sep 24, 2004 (123)
rs59813703 May 25, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
49003248, ss3941825854 NC_000023.10:49115885:T:A NC_000023.11:49259428:T:A (self)
ss83511396, ss85612118, ss85773788 NC_000023.8:48872256:T:C NC_000023.11:49259428:T:C (self)
ss112882533, ss114698373, ss115613764, ss164894611, ss204234037, ss208903867, ss255994886, ss283749161, ss294449649, ss3643782540 NC_000023.9:49002829:T:C NC_000023.11:49259428:T:C (self)
82342188, 45463674, 9554203, 49003248, 697519, 21375537, 43419702, 11565660, 92362899, 45463674, 10018694, ss341475238, ss537058048, ss566863659, ss662799226, ss1082911165, ss1432040966, ss1554366614, ss1583389266, ss1640734753, ss1683728786, ss1711581759, ss1939333615, ss1971376301, ss2159049306, ss2629701929, ss2710169700, ss2978643862, ss3019943371, ss3630431435, ss3638858277, ss3641255844, ss3770148758, ss3788898322, ss3793762871, ss3798647977, ss3836168103, ss3841695917, ss3891402722, ss3941825854, ss3984765729, ss5234393592 NC_000023.10:49115885:T:C NC_000023.11:49259428:T:C (self)
3982130, 428123377, 685891720, 10508831030, ss2317255513, ss3029047071, ss3610483482, ss3651273069, ss3822976724, ss3847216128, ss5122285363 NC_000023.11:49259428:T:C NC_000023.11:49259428:T:C (self)
ss17290902, ss21025426 NT_011568.13:5505527:T:C NC_000023.11:49259428:T:C (self)
ss61709536 NT_079573.2:11965811:T:C NC_000023.11:49259428:T:C (self)
ss3179677, ss43585179, ss74995501, ss105731537, ss119422462, ss133967201, ss157468873, ss173196090 NT_079573.4:11967629:T:C NC_000023.11:49259428:T:C (self)
43419702, ss3891402722 NC_000023.10:49115885:T:G NC_000023.11:49259428:T:G (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

47 citations for rs2232365
PMID Title Author Year Journal
19141582 Autoimmune thyroiditis and diabetes: dissecting the joint genetic susceptibility in a large cohort of multiplex families. Villano MJ et al. 2009 The Journal of clinical endocrinology and metabolism
20942809 Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases. Inoue N et al. 2010 Clinical and experimental immunology
21876709 Association between functional polymorphisms of Foxp3 gene and the occurrence of unexplained recurrent spontaneous abortion in a Chinese Han population. Wu Z et al. 2012 Clinical & developmental immunology
22239151 Genetic association of FOXP3 gene polymorphisms with allograft rejection in renal transplant patients. Qiu XY et al. 2012 Nephrology (Carlton, Vic.)
23582052 Association between FOXP3 polymorphisms and vitiligo in a Han Chinese population. Song P et al. 2013 The British journal of dermatology
25499308 The transcription factor Forkhead Box P3 gene variants affect idiopathic recurrent pregnancy loss. Saxena D et al. 2015 Placenta
26794449 Association of functional genetic variants of transcription factor Forkhead Box P3 and Nuclear Factor-κB with end-stage renal disease and renal allograft outcome. Misra MK et al. 2016 Gene
27014188 Dissecting the Genetic Susceptibility to Graves' Disease in a Cohort of Patients of Italian Origin. Lombardi A et al. 2016 Frontiers in endocrinology
27702400 Association of aplastic anemia and FoxP3 gene polymorphisms in Koreans. In JW et al. 2017 Hematology (Amsterdam, Netherlands)
27747372 FOXP3 rs3761548 polymorphism is associated with tacrolimus-induced acute nephrotoxicity in renal transplant patients. Wu Z et al. 2017 European journal of clinical pharmacology
27751813 FOXP3 gene variations and susceptibility to autism: A case-control study. Safari MR et al. 2017 Gene
27830498 Wilms' tumor susceptibility: possible involvement of FOXP3 and CXCL12 genes. Ozawa PM et al. 2016 Molecular and cellular pediatrics
27834806 X-Linked miRNAs Associated with Gender Differences in Rheumatoid Arthritis. Khalifa O et al. 2016 International journal of molecular sciences
28253599 [Association of ulcerative colitis with fork head/winged helix transcription factor-3 gene polymorphisms in Chinese patients]. Zhang DG et al. 2017 Zhonghua nei ke za zhi
28298239 Associations of FoxP3 gene polymorphisms with severe recurrent respiratory papillomatosis in Korean patients. Kwon TK et al. 2017 Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
28643491 Association of Foxp3 Polymorphism With Allograft Outcome in Kidney Transplantation. Park H et al. 2017 Annals of laboratory medicine
28713192 <i>FOXP3</i> Allelic Variants and Haplotype Structures Are Associated with Aggressive Breast Cancer Subtypes. Banin Hirata BK et al. 2017 Disease markers
28741671 The Impact of FOXP3 Polymorphism on the Risk of Allergic Rhinitis: A Meta-Analysis. Zhang G et al. 2017 Annals of human genetics
29020928 G allele at -924 A &gt; G position of FoxP3 gene promoter as a risk factor for tuberculosis. Beiranvand E et al. 2017 BMC infectious diseases
29101067 FOXP3 rs3761549 polymorphism predicts long-term renal allograft function in patients receiving cyclosporine-based immunosuppressive regimen. Xu QX et al. 2018 Gene
29206055 Association study of FOXP3 gene and the risk of 0020 pre-eclampsia. Gholami M et al. 2018 Clinical and experimental hypertension (New York, N.Y.
29404469 Significant association between <i>FOXP3</i> gene polymorphism and steroid-resistant acute rejection in living donor liver transplantation. Verma S et al. 2017 Hepatology communications
29476189 The synergic effects of CTLA-4/Foxp3-related genotypes and chromosomal aberrations on the risk of recurrent spontaneous abortion among a Chinese Han population. Fan Q et al. 2018 Journal of human genetics
29602154 The association of IL-33 and Foxp3 gene polymorphisms with recurrent pregnancy loss in Egyptian women. Zidan HE et al. 2018 Cytokine
30027704 Association of FOXP3 Single Nucleotide Polymorphisms With Clinical Outcomes After Allogenic Hematopoietic Stem Cell Transplantation. Nam M et al. 2018 Annals of laboratory medicine
30168273 FOXP3 rs3761548 polymorphism is associated with knee osteoarthritis in a Turkish population. Cekin N et al. 2018 International journal of rheumatic diseases
30487748 Polymorphisms in mTOR and Calcineurin Signaling Pathways Are Associated With Long-Term Clinical Outcomes in Kidney Transplant Recipients. Campos-Salazar AB et al. 2018 Frontiers in pharmacology
30593749 FoxP3 gene polymorphism is associated with breast cancer in Iranian patients. Arabpour F et al. 2018 Experimental oncology
30614205 Impact of TBX21, GATA3, and FOXP3 gene polymorphisms on acute cellular rejection after liver transplantation. Thude H et al. 2019 HLA
30710380 Association of Crohn's disease with Foxp3 gene polymorphisms and its colonic expression in Chinese patients. Xia S et al. 2019 Journal of clinical laboratory analysis
30781715 Genetic Epidemiology of Breast Cancer in Latin America. Zavala VA et al. 2019 Genes
30784062 Influence of forkhead box protein 3 polymorphisms (rs2232365, rs3761548) with the outcome of pregnancy: A meta-analysis. Hosseini Teshnizi S et al. 2019 Journal of cellular physiology
30875252 Association of Foxp3 and TGF-β1 Polymorphisms with Pre-Eclampsia Risk in Chinese Women. Chen J et al. 2019 Genetic testing and molecular biomarkers
30918515 Association of Ulcerative Colitis with <i>FOXP3</i> Gene Polymorphisms and Its Colonic Expression in Chinese Patients. Xia SL et al. 2019 Gastroenterology research and practice
31177386 FOXP3 immunoregulatory gene variants are independent predictors of human papillomavirus infection and cervical cancer precursor lesions. Cezar-Dos-Santos F et al. 2019 Journal of cancer research and clinical oncology
31567981 Meta-analysis of FOXP3 gene rs3761548 and rs2232365 polymorphism and multiple sclerosis susceptibility. Zhang Y et al. 2019 Medicine
31917889 Altered expression of nuclear factor of activated T cells, forkhead box P3, and immune-suppressive genes in regulatory T cells of generalized vitiligo patients. Giri PS et al. 2020 Pigment cell & melanoma research
32037623 Evaluation of Forkhead Box P3 gene polymorphisms in chronic HBV infection. Akgöllü E et al. 2020 The journal of gene medicine
32401107 The role of two common <i>FOXP3</i> gene promoter polymorphisms in preeclampsia in a Turkish population: a case-control study. Cekin N et al. 2020 Journal of obstetrics and gynaecology
32529476 The association between IL18, FOXP3 and IL13 genes polymorphisms and risk of allergic rhinitis: a meta-analysis. Tang L et al. 2020 Inflammation research
32634048 <i>FOXP3</i> Genetic Variants Do Not Impact Circulating and Cervical Interleukin-10 Levels in Human Papillomavirus Infection in Women. Cezar-Dos-Santos F et al. 2020 Viral immunology
32743104 Polymorphisms in the TGFB1 and FOXP3 genes are associated with the presence of antinuclear antibodies in chronic hepatitis C. de Castro GLC et al. 2020 Heliyon
32894076 Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia. Guad RM et al. 2020 BMC nephrology
33213373 Sex and FOXP3 gene rs2232365 polymorphism may be associated with the clinical and pathological aspects of chronic viral diseases. Pereira LMS et al. 2020 BMC immunology
33274669 Association of forkhead box P3 gene polymorphisms with premature ovarian insufficiency in Chinese women. Zhong C et al. 2021 Gynecological endocrinology
33317466 Novel association between FOXO3 rs2232365 polymorphism and late-onset preeclampsia: a case-control candidate genetic study. Pan X et al. 2020 BMC pregnancy and childbirth
33686190 Haplotypes of FOXP3 genetic variants are associated with susceptibility, autoantibodies, and TGF-β1 in patients with systemic lupus erythematosus. Stadtlober NP et al. 2021 Scientific reports
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The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post676+237644a