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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs1800849

Current Build 154

Released April 21, 2020

Organism
Homo sapiens
Position
chr11:74009120 (GRCh38.p12) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
G>A / G>C / G>T
Variation Type
SNV Single Nucleotide Variation
Frequency
A=0.200234 (25143/125568, TOPMED)
A=0.22926 (11917/51980, ALFA Project)
A=0.23547 (7374/31316, GnomAD) (+ 15 more)
A=0.1861 (932/5008, 1000G)
A=0.3161 (1416/4480, Estonian)
A=0.2377 (916/3854, ALSPAC)
A=0.2449 (908/3708, TWINSUK)
A=0.3000 (879/2930, KOREAN)
A=0.2104 (438/2082, HGDP_Stanford)
A=0.1556 (294/1890, HapMap)
A=0.2937 (538/1832, Korea1K)
A=0.239 (239/998, GoNL)
A=0.322 (193/600, NorthernSweden)
A=0.111 (24/216, Qatari)
A=0.241 (52/216, Vietnamese)
G=0.425 (85/200, SGDP_PRJ)
A=0.25 (10/40, GENOME_DK)
G=0.38 (13/34, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
UCP3 : 5 Prime UTR Variant
Publications
30 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p12 chr 11 NC_000011.10:g.74009120G>A
GRCh38.p12 chr 11 NC_000011.10:g.74009120G>C
GRCh38.p12 chr 11 NC_000011.10:g.74009120G>T
GRCh37.p13 chr 11 NC_000011.9:g.73720165G>A
GRCh37.p13 chr 11 NC_000011.9:g.73720165G>C
GRCh37.p13 chr 11 NC_000011.9:g.73720165G>T
UCP3 RefSeqGene NG_011515.1:g.5118C>T
UCP3 RefSeqGene NG_011515.1:g.5118C>G
UCP3 RefSeqGene NG_011515.1:g.5118C>A
Gene: UCP3, uncoupling protein 3 (minus strand)
Molecule type Change Amino acid[Codon] SO Term
UCP3 transcript variant short NM_022803.2:c.-238= N/A 5 Prime UTR Variant
UCP3 transcript variant long NM_003356.4:c. N/A Genic Upstream Transcript Variant
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

ALFA Allele Frequency (New)
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20200227123210
Population Group Sample Size Ref Allele Alt Allele
Total Global 51980 G=0.77074 A=0.22926
European Sub 41302 G=0.76025 A=0.23975
African Sub 2174 G=0.8832 A=0.1168
African Others Sub 54 G=0.98 A=0.02
African American Sub 2120 G=0.8807 A=0.1193
Asian Sub 118 G=0.737 A=0.263
East Asian Sub 74 G=0.77 A=0.23
Other Asian Sub 44 G=0.68 A=0.32
Latin American 1 Sub 164 G=0.848 A=0.152
Latin American 2 Sub 2228 G=0.8618 A=0.1382
South Asian Sub 4852 G=0.7570 A=0.2430
Other Sub 1142 G=0.8091 A=0.1909


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 125568 G=0.799766 A=0.200234
ALFA Total Global 51980 G=0.77074 A=0.22926
ALFA European Sub 41302 G=0.76025 A=0.23975
ALFA South Asian Sub 4852 G=0.7570 A=0.2430
ALFA Latin American 2 Sub 2228 G=0.8618 A=0.1382
ALFA African Sub 2174 G=0.8832 A=0.1168
ALFA Other Sub 1142 G=0.8091 A=0.1909
ALFA Latin American 1 Sub 164 G=0.848 A=0.152
ALFA Asian Sub 118 G=0.737 A=0.263
gnomAD - Genomes Global Study-wide 31316 G=0.76453 A=0.23547
gnomAD - Genomes European Sub 18852 G=0.71929 A=0.28071
gnomAD - Genomes African Sub 8698 G=0.8711 A=0.1289
gnomAD - Genomes East Asian Sub 1544 G=0.6917 A=0.3083
gnomAD - Genomes Other Sub 1084 G=0.7251 A=0.2749
gnomAD - Genomes American Sub 848 G=0.866 A=0.134
gnomAD - Genomes Ashkenazi Jewish Sub 290 G=0.748 A=0.252
1000Genomes Global Study-wide 5008 G=0.8139 A=0.1861
1000Genomes African Sub 1322 G=0.9039 A=0.0961
1000Genomes East Asian Sub 1008 G=0.7212 A=0.2788
1000Genomes Europe Sub 1006 G=0.7694 A=0.2306
1000Genomes South Asian Sub 978 G=0.776 A=0.224
1000Genomes American Sub 694 G=0.895 A=0.105
Genetic variation in the Estonian population Estonian Study-wide 4480 G=0.6839 A=0.3161
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 G=0.7623 A=0.2377
UK 10K study - Twins TWIN COHORT Study-wide 3708 G=0.7551 A=0.2449
KOREAN population from KRGDB KOREAN Study-wide 2930 G=0.7000 A=0.3000, C=0.0000
HGDP-CEPH-db Supplement 1 Global Study-wide 2082 G=0.7896 A=0.2104
HGDP-CEPH-db Supplement 1 Est_Asia Sub 468 G=0.684 A=0.316
HGDP-CEPH-db Supplement 1 Central_South_Asia Sub 414 G=0.713 A=0.287
HGDP-CEPH-db Supplement 1 Middle_Est Sub 350 G=0.891 A=0.109
HGDP-CEPH-db Supplement 1 Europe Sub 320 G=0.794 A=0.206
HGDP-CEPH-db Supplement 1 Africa Sub 242 G=0.901 A=0.099
HGDP-CEPH-db Supplement 1 America Sub 216 G=0.856 A=0.144
HGDP-CEPH-db Supplement 1 Oceania Sub 72 G=0.83 A=0.17
HapMap Global Study-wide 1890 G=0.8444 A=0.1556
HapMap American Sub 770 G=0.796 A=0.204
HapMap African Sub 690 G=0.952 A=0.048
HapMap Asian Sub 254 G=0.697 A=0.303
HapMap Europe Sub 176 G=0.847 A=0.153
Korean Genome Project KOREAN Study-wide 1832 G=0.7063 A=0.2937
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 G=0.761 A=0.239
Northern Sweden ACPOP Study-wide 600 G=0.678 A=0.322
Qatari Global Study-wide 216 G=0.889 A=0.111
A Vietnamese Genetic Variation Database Global Study-wide 216 G=0.759 A=0.241
SGDP_PRJ Global Study-wide 200 G=0.425 A=0.575
The Danish reference pan genome Danish Study-wide 40 G=0.75 A=0.25
Siberian Global Study-wide 34 G=0.38 A=0.62
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement G= A C T
GRCh38.p12 chr 11 NC_000011.10:g.74009120= NC_000011.10:g.74009120G>A NC_000011.10:g.74009120G>C NC_000011.10:g.74009120G>T
GRCh37.p13 chr 11 NC_000011.9:g.73720165= NC_000011.9:g.73720165G>A NC_000011.9:g.73720165G>C NC_000011.9:g.73720165G>T
UCP3 RefSeqGene NG_011515.1:g.5118= NG_011515.1:g.5118C>T NG_011515.1:g.5118C>G NG_011515.1:g.5118C>A
UCP3 transcript variant short NM_022803.2:c.-238= NM_022803.2:c.-238C>T NM_022803.2:c.-238C>G NM_022803.2:c.-238C>A
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

84 SubSNP, 18 Frequency submissions
No Submitter Submission ID Date (Build)
1 HGBASE ss2420994 Nov 14, 2000 (89)
2 YUSUKE ss2990733 Jun 15, 2001 (96)
3 CUORCGL ss12568601 Aug 26, 2003 (117)
4 SNP500CANCER ss12675681 Nov 17, 2003 (118)
5 CSHL-HAPMAP ss19913660 Feb 27, 2004 (120)
6 IMCJ-GDT ss28502666 Sep 24, 2004 (126)
7 ABI ss38752864 Mar 11, 2006 (126)
8 STEJUSTINE-REGGEN ss51854779 Mar 16, 2006 (126)
9 ILLUMINA ss65748799 Oct 13, 2006 (127)
10 KRIBB_YJKIM ss65837365 Nov 29, 2006 (127)
11 AFFY ss66266768 Nov 29, 2006 (127)
12 ILLUMINA ss67197023 Nov 29, 2006 (127)
13 ILLUMINA ss67586000 Nov 29, 2006 (127)
14 ILLUMINA ss68188865 Dec 12, 2006 (127)
15 ILLUMINA ss70675235 May 23, 2008 (130)
16 ILLUMINA ss71238248 May 16, 2007 (127)
17 ILLUMINA ss75632283 Dec 07, 2007 (129)
18 AFFY ss76411667 Dec 08, 2007 (130)
19 KRIBB_YJKIM ss83877506 Dec 14, 2007 (130)
20 BCMHGSC_JDW ss88639437 Mar 24, 2008 (129)
21 SHGC ss95216260 Feb 04, 2009 (130)
22 BGI ss106752019 Feb 04, 2009 (130)
23 ILLUMINA-UK ss119893536 Dec 01, 2009 (131)
24 ENSEMBL ss132647324 Dec 01, 2009 (131)
25 ILLUMINA ss153736523 Dec 01, 2009 (131)
26 ILLUMINA ss159329769 Dec 01, 2009 (131)
27 COMPLETE_GENOMICS ss168566122 Jul 04, 2010 (132)
28 ILLUMINA ss172925122 Jul 04, 2010 (132)
29 AFFY ss173505296 Jul 04, 2010 (132)
30 COMPLETE_GENOMICS ss175184951 Jul 04, 2010 (132)
31 1000GENOMES ss225313244 Jul 14, 2010 (132)
32 1000GENOMES ss235611341 Jul 15, 2010 (132)
33 1000GENOMES ss242233375 Jul 15, 2010 (132)
34 ILLUMINA ss244285083 Jul 04, 2010 (132)
35 BL ss255277245 May 09, 2011 (134)
36 GMI ss281065291 May 04, 2012 (137)
37 PJP ss291072612 May 09, 2011 (134)
38 ILLUMINA ss532826274 Sep 08, 2015 (146)
39 SSMP ss658166097 Apr 25, 2013 (138)
40 ILLUMINA ss832841778 Aug 21, 2014 (142)
41 ILLUMINA ss833432608 Aug 21, 2014 (142)
42 EVA-GONL ss988674704 Aug 21, 2014 (142)
43 JMKIDD_LAB ss1077832723 Aug 21, 2014 (142)
44 1000GENOMES ss1341881600 Aug 21, 2014 (142)
45 EVA_GENOME_DK ss1575793162 Apr 01, 2015 (144)
46 EVA_DECODE ss1598335884 Apr 01, 2015 (144)
47 EVA_UK10K_ALSPAC ss1626893414 Apr 01, 2015 (144)
48 EVA_UK10K_TWINSUK ss1669887447 Apr 01, 2015 (144)
49 EVA_SVP ss1713264100 Apr 01, 2015 (144)
50 HAMMER_LAB ss1806876230 Sep 08, 2015 (146)
51 WEILL_CORNELL_DGM ss1932032411 Feb 12, 2016 (147)
52 JJLAB ss2026760375 Sep 14, 2016 (149)
53 USC_VALOUEV ss2155071116 Dec 20, 2016 (150)
54 HUMAN_LONGEVITY ss2183534491 Dec 20, 2016 (150)
55 TOPMED ss2347020703 Dec 20, 2016 (150)
56 SYSTEMSBIOZJU ss2627853898 Nov 08, 2017 (151)
57 ILLUMINA ss2635027737 Nov 08, 2017 (151)
58 GRF ss2699365956 Nov 08, 2017 (151)
59 ILLUMINA ss2710739412 Nov 08, 2017 (151)
60 GNOMAD ss2901400679 Nov 08, 2017 (151)
61 SWEGEN ss3008345341 Nov 08, 2017 (151)
62 BIOINF_KMB_FNS_UNIBA ss3027177421 Nov 08, 2017 (151)
63 TOPMED ss3149364522 Nov 08, 2017 (151)
64 TOPMED ss3149364523 Nov 08, 2017 (151)
65 CSHL ss3349667182 Nov 08, 2017 (151)
66 ILLUMINA ss3626690020 Oct 12, 2018 (152)
67 ILLUMINA ss3637915508 Oct 12, 2018 (152)
68 ILLUMINA ss3638971345 Oct 12, 2018 (152)
69 ILLUMINA ss3639796748 Oct 12, 2018 (152)
70 ILLUMINA ss3642913172 Oct 12, 2018 (152)
71 ILLUMINA ss3643848826 Oct 12, 2018 (152)
72 OMUKHERJEE_ADBS ss3646430066 Oct 12, 2018 (152)
73 EGCUT_WGS ss3675664435 Jul 13, 2019 (153)
74 EVA_DECODE ss3692081263 Jul 13, 2019 (153)
75 ACPOP ss3738304676 Jul 13, 2019 (153)
76 EVA ss3749480938 Jul 13, 2019 (153)
77 KHV_HUMAN_GENOMES ss3814816872 Jul 13, 2019 (153)
78 EVA ss3832700441 Apr 26, 2020 (154)
79 EVA ss3839909073 Apr 26, 2020 (154)
80 EVA ss3845389251 Apr 26, 2020 (154)
81 HGDP ss3847422185 Apr 26, 2020 (154)
82 SGDP_PRJ ss3876572927 Apr 26, 2020 (154)
83 KRGDB ss3924978584 Apr 26, 2020 (154)
84 KOGIC ss3970235362 Apr 26, 2020 (154)
85 1000Genomes NC_000011.9 - 73720165 Oct 12, 2018 (152)
86 The Avon Longitudinal Study of Parents and Children NC_000011.9 - 73720165 Oct 12, 2018 (152)
87 Genetic variation in the Estonian population NC_000011.9 - 73720165 Oct 12, 2018 (152)
88 The Danish reference pan genome NC_000011.9 - 73720165 Apr 26, 2020 (154)
89 gnomAD - Genomes NC_000011.9 - 73720165 Jul 13, 2019 (153)
90 Genome of the Netherlands Release 5 NC_000011.9 - 73720165 Apr 26, 2020 (154)
91 HGDP-CEPH-db Supplement 1 NC_000011.8 - 73397813 Apr 26, 2020 (154)
92 HapMap NC_000011.10 - 74009120 Apr 26, 2020 (154)
93 KOREAN population from KRGDB NC_000011.9 - 73720165 Apr 26, 2020 (154)
94 Korean Genome Project NC_000011.10 - 74009120 Apr 26, 2020 (154)
95 Northern Sweden NC_000011.9 - 73720165 Jul 13, 2019 (153)
96 Qatari NC_000011.9 - 73720165 Apr 26, 2020 (154)
97 SGDP_PRJ NC_000011.9 - 73720165 Apr 26, 2020 (154)
98 Siberian NC_000011.9 - 73720165 Apr 26, 2020 (154)
99 TopMed NC_000011.10 - 74009120 Oct 12, 2018 (152)
100 UK 10K study - Twins NC_000011.9 - 73720165 Oct 12, 2018 (152)
101 A Vietnamese Genetic Variation Database NC_000011.9 - 73720165 Jul 13, 2019 (153)
102 dbGaP Population Frequency Project NC_000011.10 - 74009120 Apr 26, 2020 (154)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs17848364 Mar 11, 2006 (126)
rs36207714 Oct 25, 2006 (127)
rs56493941 May 23, 2008 (130)
rs57539003 May 23, 2008 (130)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
100077, ss66266768, ss76411667, ss88639437, ss119893536, ss168566122, ss173505296, ss175184951, ss255277245, ss281065291, ss291072612, ss1598335884, ss1713264100, ss2635027737, ss3638971345, ss3639796748, ss3642913172, ss3643848826, ss3847422185 NC_000011.8:73397812:G:A NC_000011.10:74009119:G:A (self)
54424369, 30208043, 21402683, 2622710, 148637483, 13478468, 32155978, 11589541, 14074341, 28589907, 7587470, 30208043, 6701591, ss225313244, ss235611341, ss242233375, ss532826274, ss658166097, ss832841778, ss833432608, ss988674704, ss1077832723, ss1341881600, ss1575793162, ss1626893414, ss1669887447, ss1806876230, ss1932032411, ss2026760375, ss2155071116, ss2347020703, ss2627853898, ss2699365956, ss2710739412, ss2901400679, ss3008345341, ss3349667182, ss3626690020, ss3637915508, ss3646430066, ss3675664435, ss3738304676, ss3749480938, ss3832700441, ss3839909073, ss3876572927, ss3924978584 NC_000011.9:73720164:G:A NC_000011.10:74009119:G:A (self)
636907, 26613363, 66557426, 867468205, ss2183534491, ss3027177421, ss3149364522, ss3692081263, ss3814816872, ss3845389251, ss3970235362 NC_000011.10:74009119:G:A NC_000011.10:74009119:G:A (self)
ss19913660 NT_033927.6:3919193:G:A NC_000011.10:74009119:G:A (self)
ss2420994, ss2990733, ss12568601, ss12675681, ss28502666, ss38752864, ss51854779, ss65748799, ss65837365, ss67197023, ss67586000, ss68188865, ss70675235, ss71238248, ss75632283, ss83877506, ss95216260, ss106752019, ss132647324, ss153736523, ss159329769, ss172925122, ss244285083 NT_167190.1:19025959:G:A NC_000011.10:74009119:G:A (self)
32155978, ss3924978584 NC_000011.9:73720164:G:C NC_000011.10:74009119:G:C
ss3149364523 NC_000011.10:74009119:G:T NC_000011.10:74009119:G:T (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

30 citations for rs1800849
PMID Title Author Year Journal
15113403 Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis. Dvornyk V et al. 2004 BMC genetics
15157284 Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes. Long JR et al. 2004 BMC genetics
17150099 Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus. Pinelli M et al. 2006 BMC medical genetics
17870627 Association between obesity and insulin resistance with UCP2-UCP3 gene variants in Spanish children and adolescents. Ochoa MC et al. 2007 Molecular genetics and metabolism
19406964 Association of genetic variants with chronic kidney disease in Japanese individuals. Yoshida T et al. 2009 Clinical journal of the American Society of Nephrology
19653005 The combined impact of metabolic gene polymorphisms on elite endurance athlete status and related phenotypes. Ahmetov II et al. 2009 Human genetics
19736300 Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases. Mori M et al. 2009 The Journal of physiology
19769793 Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: the Finnish Diabetes Prevention Study. Salopuro T et al. 2009 BMC medical genetics
20031128 Cardiorespiratory fitness modifies the association between the UCP3-55C>T (rs1800849) polymorphism and plasma homocysteine in Swedish youth. Labayen I et al. 2010 Atherosclerosis
20802238 Population genetic analysis of the uncoupling proteins supports a role for UCP3 in human cold resistance. Hancock AM et al. 2011 Molecular biology and evolution
21074158 Mitochondrial uncoupling protein gene cluster variation (UCP2-UCP3) and the risk of incident type 2 diabetes mellitus: the Women's Genome Health Study. Zee RY et al. 2011 Atherosclerosis
21336965 A common polymorphism in the UCP3 promoter influences hand grip strength in elderly people. Crocco P et al. 2011 Biogerontology
21603268 Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional -866G>A Promoter Variant (rs659366). Dalgaard LT et al. 2011 Journal of obesity
22038464 Moderate effects of apple juice consumption on obesity-related markers in obese men: impact of diet-gene interaction on body fat content. Barth SW et al. 2012 European journal of nutrition
22216339 Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity. Rose G et al. 2011 PloS one
22241057 Variation in the uncoupling protein 2 and 3 genes and human performance. Dhamrait SS et al. 2012 Journal of applied physiology (Bethesda, Md.
22328972 A Database of Gene-Environment Interactions Pertaining to Blood Lipid Traits, Cardiovascular Disease and Type 2 Diabetes. Lee YC et al. 2011 Journal of data mining in genomics & proteomics
22879966 Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study. Verschuren JJ et al. 2012 PloS one
23639961 Uncoupling protein 2 -866G/A and uncoupling protein 3 -55C/T polymorphisms in young South African Indian coronary artery disease patients. Phulukdaree A et al. 2013 Gene
24804925 Meta-analysis reveals the association of common variants in the uncoupling protein (UCP) 1-3 genes with body mass index variability. Brondani LA et al. 2014 PloS one
25368670 CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits. Parnell LD et al. 2014 BioData mining
26483159 RETRACTED: Association between peroxisome proliferator-activated receptor, UCP3 and lipoprotein lipase gene polymorphisms and obesity in Chinese adolescents. Zou Z et al. 2017 Obesity research & clinical practice
26497592 The rs1803274 polymorphism of the BCHE gene is associated with an increased risk of coronary in-stent restenosis. Pleva L et al. 2015 BMC cardiovascular disorders
26848765 Effect of -55CT Polymorphism of UCP3 on Insulin Resistance and Cardiovascular Risk Factors after a High Protein/Low Carbohydrate versus a Standard Hypocaloric Diet. de Luis DA et al. 2016 Annals of nutrition & metabolism
27277665 Genetic risk factors for restenosis after percutaneous coronary intervention in Kazakh population. Zholdybayeva EV et al. 2016 Human genomics
27798356 Lack of replication of associations between multiple genetic polymorphisms and endurance athlete status in Japanese population. Yvert T et al. 2016 Physiological reports
28690685 Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study. Muñoz AM et al. 2017 Genes & nutrition
28977211 Association of 5-HT2C (rs3813929) and UCP3 (rs1800849) gene polymorphisms with type 2 diabetes in obese women candidates for bariatric surgery. Schnor NPP et al. 2017 Archives of endocrinology and metabolism
29529994 UCP2 and UCP3 variants and gene-environment interaction associated with prediabetes and T2DM in a rural population: a case control study in China. Su M et al. 2018 BMC medical genetics
29786102 The UCP2 -866G/A, Ala55Val and UCP3 -55C/T polymorphisms are associated with premature coronary artery disease and cardiovascular risk factors in Mexican population. Gamboa R et al. 2018 Genetics and molecular biology
Help

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:
Select flank length:

Genomic regions, transcripts, and products
Top Help

NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

Software version is: 2.0.1.post536+f5d31d6