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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs10811661

Current Build 155

Released April 9, 2021

Organism
Homo sapiens
Position
chr9:22134095 (GRCh38.p13) Help

The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.

Alleles
T>A / T>C
Variation Type
SNV Single Nucleotide Variation
Frequency
C=0.145903 (38619/264690, TOPMED)
C=0.169932 (31916/187816, ALFA)
C=0.141222 (19796/140176, GnomAD) (+ 20 more)
C=0.15170 (11938/78694, PAGE_STUDY)
C=0.42691 (7155/16760, 8.3KJPN)
C=0.1763 (883/5008, 1000G)
C=0.1353 (606/4480, Estonian)
C=0.1879 (724/3854, ALSPAC)
C=0.1775 (658/3708, TWINSUK)
C=0.4290 (1257/2930, KOREAN)
C=0.1849 (348/1882, HapMap)
C=0.4187 (767/1832, Korea1K)
C=0.1549 (176/1136, Daghestan)
C=0.185 (185/998, GoNL)
C=0.477 (377/790, PRJEB37584)
C=0.136 (85/626, Chileans)
C=0.255 (153/600, NorthernSweden)
T=0.428 (95/222, SGDP_PRJ)
C=0.139 (30/216, Qatari)
C=0.416 (89/214, Vietnamese)
C=0.26 (24/92, Ancient Sardinia)
C=0.15 (6/40, GENOME_DK)
T=0.46 (13/28, Siberian)
Clinical Significance
Not Reported in ClinVar
Gene : Consequence
None
Publications
221 citations
Genomic View
See rs on genome
Help

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements
Sequence name Change
GRCh38.p13 chr 9 NC_000009.12:g.22134095T>A
GRCh38.p13 chr 9 NC_000009.12:g.22134095T>C
GRCh37.p13 chr 9 NC_000009.11:g.22134094T>A
GRCh37.p13 chr 9 NC_000009.11:g.22134094T>C
Help

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Not Reported in ClinVar

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20201027095038
Population Group Sample Size Ref Allele Alt Allele
Total Global 187816 T=0.830068 C=0.169932
European Sub 156496 T=0.828552 C=0.171448
African Sub 9114 T=0.9343 C=0.0657
African Others Sub 330 T=0.948 C=0.052
African American Sub 8784 T=0.9337 C=0.0663
Asian Sub 3712 T=0.5741 C=0.4259
East Asian Sub 3016 T=0.5653 C=0.4347
Other Asian Sub 696 T=0.612 C=0.388
Latin American 1 Sub 1008 T=0.8532 C=0.1468
Latin American 2 Sub 7376 T=0.8712 C=0.1288
South Asian Sub 358 T=0.858 C=0.142
Other Sub 9752 T=0.8199 C=0.1801


Help

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

Download
Study Population Group Sample Size Ref Allele Alt Allele
TopMed Global Study-wide 264690 T=0.854097 C=0.145903
gnomAD - Genomes Global Study-wide 140176 T=0.858778 C=0.141222
gnomAD - Genomes European Sub 75896 T=0.83321 C=0.16679
gnomAD - Genomes African Sub 42034 T=0.93248 C=0.06752
gnomAD - Genomes American Sub 13650 T=0.83993 C=0.16007
gnomAD - Genomes Ashkenazi Jewish Sub 3324 T=0.8384 C=0.1616
gnomAD - Genomes East Asian Sub 3122 T=0.5990 C=0.4010
gnomAD - Genomes Other Sub 2150 T=0.8488 C=0.1512
The PAGE Study Global Study-wide 78694 T=0.84830 C=0.15170
The PAGE Study AfricanAmerican Sub 32514 T=0.93006 C=0.06994
The PAGE Study Mexican Sub 10810 T=0.88113 C=0.11887
The PAGE Study Asian Sub 8312 T=0.5740 C=0.4260
The PAGE Study PuertoRican Sub 7918 T=0.8534 C=0.1466
The PAGE Study NativeHawaiian Sub 4534 T=0.6409 C=0.3591
The PAGE Study Cuban Sub 4230 T=0.8343 C=0.1657
The PAGE Study Dominican Sub 3828 T=0.8764 C=0.1236
The PAGE Study CentralAmerican Sub 2450 T=0.8751 C=0.1249
The PAGE Study SouthAmerican Sub 1982 T=0.8653 C=0.1347
The PAGE Study NativeAmerican Sub 1260 T=0.8532 C=0.1468
The PAGE Study SouthAsian Sub 856 T=0.863 C=0.137
8.3KJPN JAPANESE Study-wide 16760 T=0.57309 C=0.42691
1000Genomes Global Study-wide 5008 T=0.8237 C=0.1763
1000Genomes African Sub 1322 T=0.9546 C=0.0454
1000Genomes East Asian Sub 1008 T=0.5645 C=0.4355
1000Genomes Europe Sub 1006 T=0.8320 C=0.1680
1000Genomes South Asian Sub 978 T=0.868 C=0.132
1000Genomes American Sub 694 T=0.876 C=0.124
Genetic variation in the Estonian population Estonian Study-wide 4480 T=0.8647 C=0.1353
The Avon Longitudinal Study of Parents and Children PARENT AND CHILD COHORT Study-wide 3854 T=0.8121 C=0.1879
UK 10K study - Twins TWIN COHORT Study-wide 3708 T=0.8225 C=0.1775
KOREAN population from KRGDB KOREAN Study-wide 2930 T=0.5710 A=0.0000, C=0.4290
HapMap Global Study-wide 1882 T=0.8151 C=0.1849
HapMap American Sub 770 T=0.796 C=0.204
HapMap African Sub 684 T=0.937 C=0.063
HapMap Asian Sub 252 T=0.544 C=0.456
HapMap Europe Sub 176 T=0.812 C=0.188
Korean Genome Project KOREAN Study-wide 1832 T=0.5813 C=0.4187
Genome-wide autozygosity in Daghestan Global Study-wide 1136 T=0.8451 C=0.1549
Genome-wide autozygosity in Daghestan Daghestan Sub 628 T=0.877 C=0.123
Genome-wide autozygosity in Daghestan Near_East Sub 144 T=0.854 C=0.146
Genome-wide autozygosity in Daghestan Central Asia Sub 122 T=0.746 C=0.254
Genome-wide autozygosity in Daghestan Europe Sub 108 T=0.833 C=0.167
Genome-wide autozygosity in Daghestan South Asian Sub 98 T=0.82 C=0.18
Genome-wide autozygosity in Daghestan Caucasus Sub 36 T=0.69 C=0.31
Genome of the Netherlands Release 5 Genome of the Netherlands Study-wide 998 T=0.815 C=0.185
CNV burdens in cranial meningiomas Global Study-wide 790 T=0.523 C=0.477
CNV burdens in cranial meningiomas CRM Sub 790 T=0.523 C=0.477
Chileans Chilean Study-wide 626 T=0.864 C=0.136
Northern Sweden ACPOP Study-wide 600 T=0.745 C=0.255
SGDP_PRJ Global Study-wide 222 T=0.428 C=0.572
Qatari Global Study-wide 216 T=0.861 C=0.139
A Vietnamese Genetic Variation Database Global Study-wide 214 T=0.584 C=0.416
Ancient Sardinia genome-wide 1240k capture data generation and analysis Global Study-wide 92 T=0.74 C=0.26
The Danish reference pan genome Danish Study-wide 40 T=0.85 C=0.15
Siberian Global Study-wide 28 T=0.46 C=0.54
Help

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement T= A C
GRCh38.p13 chr 9 NC_000009.12:g.22134095= NC_000009.12:g.22134095T>A NC_000009.12:g.22134095T>C
GRCh37.p13 chr 9 NC_000009.11:g.22134094= NC_000009.11:g.22134094T>A NC_000009.11:g.22134094T>C
Help

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

85 SubSNP, 23 Frequency submissions
No Submitter Submission ID Date (Build)
1 SC_SNP ss15954995 Feb 27, 2004 (120)
2 SC_SNP ss18606193 Feb 27, 2004 (120)
3 SC_SNP ss19057714 Feb 27, 2004 (120)
4 AFFY ss66064046 Nov 29, 2006 (127)
5 AFFY ss75986202 Dec 08, 2007 (130)
6 KRIBB_YJKIM ss82771277 Dec 15, 2007 (130)
7 BGI ss104605567 Dec 01, 2009 (131)
8 RSG_JCVI ss107934366 Feb 04, 2009 (130)
9 WTCCC ss120256078 Dec 01, 2009 (131)
10 ILLUMINA ss159924101 Dec 01, 2009 (131)
11 AFFY ss170043166 Jun 24, 2010 (142)
12 PAGE_STUDY ss181341851 Jul 04, 2010 (132)
13 PAGE_STUDY ss181834428 Jul 04, 2010 (132)
14 PAGE_STUDY ss181835895 Jul 04, 2010 (132)
15 1000GENOMES ss224175948 Jul 14, 2010 (132)
16 WTCCC ss230393063 Jul 04, 2010 (132)
17 1000GENOMES ss234764887 Jul 15, 2010 (132)
18 1000GENOMES ss241550389 Jul 15, 2010 (132)
19 ILLUMINA ss244270289 Jul 04, 2010 (132)
20 GMI ss280150195 May 04, 2012 (137)
21 GMI ss285987888 Apr 25, 2013 (138)
22 ILLUMINA ss410889041 Sep 17, 2011 (135)
23 BROAD_NHGRI_T2D ss411632917 Jul 19, 2016 (147)
24 ILLUMINA ss479762335 Sep 08, 2015 (146)
25 EXOME_CHIP ss491421335 May 04, 2012 (137)
26 TISHKOFF ss561303806 Apr 25, 2013 (138)
27 SSMP ss655735666 Apr 25, 2013 (138)
28 EVA-GONL ss986414542 Aug 21, 2014 (142)
29 JMKIDD_LAB ss1076193597 Aug 21, 2014 (142)
30 1000GENOMES ss1333300101 Aug 21, 2014 (142)
31 HAMMER_LAB ss1397551633 Sep 08, 2015 (146)
32 DDI ss1431782562 Apr 01, 2015 (144)
33 EVA_GENOME_DK ss1583029205 Apr 01, 2015 (144)
34 EVA_DECODE ss1596048741 Apr 01, 2015 (144)
35 EVA_UK10K_ALSPAC ss1622458202 Apr 01, 2015 (144)
36 EVA_UK10K_TWINSUK ss1665452235 Apr 01, 2015 (144)
37 EVA_SVP ss1713099093 Apr 01, 2015 (144)
38 WEILL_CORNELL_DGM ss1929697918 Feb 12, 2016 (147)
39 ILLUMINA ss1946255407 Feb 12, 2016 (147)
40 ILLUMINA ss1959173175 Feb 12, 2016 (147)
41 GENOMED ss1971178691 Jul 19, 2016 (147)
42 JJLAB ss2025560956 Sep 14, 2016 (149)
43 ILLUMINA ss2094835220 Dec 20, 2016 (150)
44 ILLUMINA ss2095220497 Dec 20, 2016 (150)
45 USC_VALOUEV ss2153787198 Dec 20, 2016 (150)
46 HUMAN_LONGEVITY ss2310213898 Dec 20, 2016 (150)
47 TOPMED ss2480291126 Dec 20, 2016 (150)
48 SYSTEMSBIOZJU ss2627255104 Nov 08, 2017 (151)
49 ILLUMINA ss2634850098 Nov 08, 2017 (151)
50 ILLUMINA ss2634850099 Nov 08, 2017 (151)
51 ILLUMINA ss2635194098 Nov 08, 2017 (151)
52 GRF ss2709591773 Nov 08, 2017 (151)
53 ILLUMINA ss2711159951 Nov 08, 2017 (151)
54 GNOMAD ss2876542304 Nov 08, 2017 (151)
55 AFFY ss2985458499 Nov 08, 2017 (151)
56 AFFY ss2986104589 Nov 08, 2017 (151)
57 SWEGEN ss3004538153 Nov 08, 2017 (151)
58 ILLUMINA ss3022917204 Nov 08, 2017 (151)
59 BIOINF_KMB_FNS_UNIBA ss3026570211 Nov 08, 2017 (151)
60 CSHL ss3348570207 Nov 08, 2017 (151)
61 TOPMED ss3584610172 Nov 08, 2017 (151)
62 ILLUMINA ss3625980850 Oct 12, 2018 (152)
63 ILLUMINA ss3636952435 Oct 12, 2018 (152)
64 ILLUMINA ss3644988719 Oct 12, 2018 (152)
65 ILLUMINA ss3653468368 Oct 12, 2018 (152)
66 ILLUMINA ss3654222526 Oct 12, 2018 (152)
67 EGCUT_WGS ss3672284650 Jul 13, 2019 (153)
68 EVA_DECODE ss3723661857 Jul 13, 2019 (153)
69 ILLUMINA ss3726601652 Jul 13, 2019 (153)
70 ACPOP ss3736393870 Jul 13, 2019 (153)
71 ILLUMINA ss3744317644 Jul 13, 2019 (153)
72 ILLUMINA ss3744587248 Jul 13, 2019 (153)
73 EVA ss3769037098 Jul 13, 2019 (153)
74 PAGE_CC ss3771492532 Jul 13, 2019 (153)
75 JVAR_NIG-HUMG ss3798740378 Jul 13, 2019 (153)
76 KHV_HUMAN_GENOMES ss3812194174 Jul 13, 2019 (153)
77 EVA ss3831586943 Apr 26, 2020 (154)
78 SGDP_PRJ ss3871729440 Apr 26, 2020 (154)
79 KRGDB ss3919387880 Apr 26, 2020 (154)
80 KOGIC ss3965479750 Apr 26, 2020 (154)
81 EVA ss3984617755 Apr 26, 2021 (155)
82 EVA ss3985412212 Apr 26, 2021 (155)
83 TOPMED ss4816112229 Apr 26, 2021 (155)
84 TOMMO_GENOMICS ss5192521333 Apr 26, 2021 (155)
85 EVA ss5237456872 Apr 26, 2021 (155)
86 1000Genomes NC_000009.11 - 22134094 Oct 12, 2018 (152)
87 The Avon Longitudinal Study of Parents and Children NC_000009.11 - 22134094 Oct 12, 2018 (152)
88 Chileans NC_000009.11 - 22134094 Apr 26, 2020 (154)
89 Genome-wide autozygosity in Daghestan NC_000009.10 - 22124094 Apr 26, 2020 (154)
90 Genetic variation in the Estonian population NC_000009.11 - 22134094 Oct 12, 2018 (152)
91 The Danish reference pan genome NC_000009.11 - 22134094 Apr 26, 2020 (154)
92 gnomAD - Genomes NC_000009.12 - 22134095 Apr 26, 2021 (155)
93 Genome of the Netherlands Release 5 NC_000009.11 - 22134094 Apr 26, 2020 (154)
94 HapMap NC_000009.12 - 22134095 Apr 26, 2020 (154)
95 KOREAN population from KRGDB NC_000009.11 - 22134094 Apr 26, 2020 (154)
96 Korean Genome Project NC_000009.12 - 22134095 Apr 26, 2020 (154)
97 Northern Sweden NC_000009.11 - 22134094 Jul 13, 2019 (153)
98 The PAGE Study NC_000009.12 - 22134095 Jul 13, 2019 (153)
99 Ancient Sardinia genome-wide 1240k capture data generation and analysis NC_000009.11 - 22134094 Apr 26, 2021 (155)
100 CNV burdens in cranial meningiomas NC_000009.11 - 22134094 Apr 26, 2021 (155)
101 Qatari NC_000009.11 - 22134094 Apr 26, 2020 (154)
102 SGDP_PRJ NC_000009.11 - 22134094 Apr 26, 2020 (154)
103 Siberian NC_000009.11 - 22134094 Apr 26, 2020 (154)
104 8.3KJPN NC_000009.11 - 22134094 Apr 26, 2021 (155)
105 TopMed NC_000009.12 - 22134095 Apr 26, 2021 (155)
106 UK 10K study - Twins NC_000009.11 - 22134094 Oct 12, 2018 (152)
107 A Vietnamese Genetic Variation Database NC_000009.11 - 22134094 Jul 13, 2019 (153)
108 ALFA NC_000009.12 - 22134095 Apr 26, 2021 (155)
Help

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID History Updated (Build)
rs56432185 May 24, 2008 (130)
rs60839437 Feb 26, 2009 (130)
rs111169537 Aug 21, 2014 (142)
Added to this RefSNP Cluster:
Submission IDs Observation SPDI Canonical SPDI Source RSIDs
26565274, ss3919387880 NC_000009.11:22134093:T:A NC_000009.12:22134094:T:A (self)
525172, ss66064046, ss75986202, ss170043166, ss280150195, ss285987888, ss1397551633, ss1596048741, ss1713099093, ss2635194098 NC_000009.10:22124093:T:C NC_000009.12:22134094:T:C (self)
45539431, 25332118, 456289, 18022898, 9194142, 11299891, 26565274, 9678735, 638139, 167200, 11739848, 23746420, 6303552, 50490640, 25332118, 5627092, ss224175948, ss234764887, ss241550389, ss479762335, ss491421335, ss561303806, ss655735666, ss986414542, ss1076193597, ss1333300101, ss1431782562, ss1583029205, ss1622458202, ss1665452235, ss1929697918, ss1946255407, ss1959173175, ss1971178691, ss2025560956, ss2094835220, ss2095220497, ss2153787198, ss2480291126, ss2627255104, ss2634850098, ss2634850099, ss2709591773, ss2711159951, ss2876542304, ss2985458499, ss2986104589, ss3004538153, ss3022917204, ss3348570207, ss3625980850, ss3636952435, ss3644988719, ss3653468368, ss3654222526, ss3672284650, ss3736393870, ss3744317644, ss3744587248, ss3769037098, ss3798740378, ss3831586943, ss3871729440, ss3919387880, ss3984617755, ss3985412212, ss5192521333, ss5237456872 NC_000009.11:22134093:T:C NC_000009.12:22134094:T:C (self)
320970800, 3801010, 21857751, 714001, 408190781, 653489790, 7469868109, ss2310213898, ss3026570211, ss3584610172, ss3723661857, ss3726601652, ss3771492532, ss3812194174, ss3965479750, ss4816112229 NC_000009.12:22134094:T:C NC_000009.12:22134094:T:C (self)
ss15954995, ss18606193, ss19057714 NT_008413.16:22124093:T:C NC_000009.12:22134094:T:C (self)
ss230393063 NT_008413.17:22124093:T:C NC_000009.12:22134094:T:C (self)
ss82771277, ss104605567, ss107934366, ss120256078, ss159924101, ss181341851, ss181834428, ss181835895, ss244270289, ss410889041, ss411632917 NT_008413.18:22124093:T:C NC_000009.12:22134094:T:C (self)
Help

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

221 citations for rs10811661
PMID Title Author Year Journal
17786212 Heterogeneity in meta-analyses of genome-wide association investigations. Ioannidis JP et al. 2007 PloS one
17827400 Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies. Grarup N et al. 2007 Diabetes
17928989 Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population. Horikoshi M et al. 2007 Diabetologia
18162508 Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population. Omori S et al. 2008 Diabetes
18176561 The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Helgadottir A et al. 2008 Nature genetics
18224312 Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. Brockmöller J et al. 2008 European journal of clinical pharmacology
18224336 Haplotypic analysis of Wellcome Trust Case Control Consortium data. Browning BL et al. 2008 Human genetics
18264689 Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion. Kirchhoff K et al. 2008 Diabetologia
18368387 Strong association of common variants in the CDKN2A/CDKN2B region with type 2 diabetes in French Europids. Duesing K et al. 2008 Diabetologia
18423522 Estimating odds ratios in genome scans: an approximate conditional likelihood approach. Ghosh A et al. 2008 American journal of human genetics
18426861 Association analysis of type 2 diabetes Loci in type 1 diabetes. Qu HQ et al. 2008 Diabetes
18437351 Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study). Hertel JK et al. 2008 Diabetologia
18443202 Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies. Lewis JP et al. 2008 Diabetes
18461161 Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value. Cauchi S et al. 2008 PloS one
18469204 Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Ng MC et al. 2008 Diabetes
18477659 Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan. Horikawa Y et al. 2008 The Journal of clinical endocrinology and metabolism
18533027 Worldwide population differentiation at disease-associated SNPs. Myles S et al. 2008 BMC medical genomics
18544707 Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program. Moore AF et al. 2008 Diabetes
18565990 Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence. Saccone SF et al. 2008 Bioinformatics (Oxford, England)
18591388 Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk. Lango H et al. 2008 Diabetes
18598350 Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. Sanghera DK et al. 2008 BMC medical genetics
18633108 Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Wu Y et al. 2008 Diabetes
18689899 Exchangeable models of complex inherited diseases. Slatkin M et al. 2008 Genetics
18694974 Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. van Hoek M et al. 2008 Diabetes
18782870 Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008. Florez JC et al. 2008 The Journal of clinical endocrinology and metabolism
18991055 Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population. Lee YH et al. 2008 Journal of human genetics
19002430 Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population. Cho YM et al. 2009 Diabetologia
19008344 Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians. Rong R et al. 2009 Diabetes
19019192 Association of genetic variation on chromosome 9p21.3 and arterial stiffness. Björck HM et al. 2009 Journal of internal medicine
19020323 Genotype score in addition to common risk factors for prediction of type 2 diabetes. Meigs JB et al. 2008 The New England journal of medicine
19033397 Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. Tabara Y et al. 2009 Diabetes
19033589 Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. Doria A et al. 2008 JAMA
19056611 Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. Timpson NJ et al. 2009 Diabetes
19096518 Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study. Paré G et al. 2008 PLoS genetics
19207020 Meta-analysis in genome-wide association studies. Zeggini E et al. 2009 Pharmacogenomics
19214202 Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. Schaefer AS et al. 2009 PLoS genetics
19228808 Type 2 diabetes risk alleles are associated with reduced size at birth. Freathy RM et al. 2009 Diabetes
19258437 Genetic variant in the IGF2BP2 gene may interact with fetal malnutrition to affect glucose metabolism. van Hoek M et al. 2009 Diabetes
19279076 Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men. Qi L et al. 2009 The American journal of clinical nutrition
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The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

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NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
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