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Verghese M, Wilkinson E, He YY. Role of RNA modifications in carcinogenesis and carcinogen damage response. Mol Carcinog. 2023 Jan;62(1):24-37. doi: 10.1002/mc.23418. Epub 2022 May 13. PubMed PMID: 35560957; PubMed Central PMCID: PMC9653521.
Park G, Cui YH, Yang S, Sun M, Wilkinson E, Li H, Zhang YB, Chen J, Bissonnette M, Lin W, He YY. Moderate Low UVB Irradiation Modulates Tumor-associated Macrophages and Dendritic Cells and Promotes Antitumor Immunity in Tumor-bearing Mice. Photochem Photobiol. 2022 Jul 29;. doi: 10.1111/php.13684. [Epub ahead of print] PubMed PMID: 35962531; NIHMSID:NIHMS1828849.
Zhang R, Chen D, Fan H, Wu R, Tu J, Zhang FQ, Wang M, Zheng H, Qu CK, Elf SE, Faubert B, He YY, Bissonnette MB, Gao X, DeBerardinis RJ, Chen J. Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells. Cell Chem Biol. 2022 Jul 21;29(7):1200-1208.e6. doi: 10.1016/j.chembiol.2022.03.010. Epub 2022 Apr 15. PubMed PMID: 35429459; PubMed Central PMCID: PMC9308720.
Gao X, Liu Y, Li Y, Fan H, Wu R, Zhang R, Faubert B, He YY, Bissonnette MB, Xia S, Chen D, Mao H, Boggon TJ, Chen J. Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation. Mol Cell. 2022 Jun 2;82(11):1992-2005.e9. doi: 10.1016/j.molcel.2022.03.026. Epub 2022 Apr 12. PubMed PMID: 35417664; PubMed Central PMCID: PMC9177793.
Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C. FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development. Science. 2022 May 27;376(6596):968-973. doi: 10.1126/science.abe9582. Epub 2022 May 5. PubMed PMID: 35511947; PubMed Central PMCID: PMC9746489.
Wilkinson E, Cui YH, He YY. Roles of RNA Modifications in Diverse Cellular Functions. Front Cell Dev Biol. 2022;10:828683. doi: 10.3389/fcell.2022.828683. eCollection 2022. Review. PubMed PMID: 35350378; PubMed Central PMCID: PMC8957929.
Qiang L, Yang S, Cui YH, He YY. Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing. Autophagy. 2021 Sep;17(9):2128-2143. doi: 10.1080/15548627.2020.1816342. Epub 2020 Sep 18. PubMed PMID: 32866426; PubMed Central PMCID: PMC8496719.
Yang Z, Yang S, Cui YH, Wei J, Shah P, Park G, Cui X, He C, He YY. METTL14 facilitates global genome repair and suppresses skin tumorigenesis. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35). doi: 10.1073/pnas.2025948118. PubMed PMID: 34452996; PubMed Central PMCID: PMC8536359.
Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 Apr 12;12(1):2183. doi: 10.1038/s41467-021-22469-6. PubMed PMID: 33846348; PubMed Central PMCID: PMC8041927.
Wilkinson E, Cui YH, He YY. Context-Dependent Roles of RNA Modifications in Stress Responses and Diseases. Int J Mol Sci. 2021 Feb 16;22(4). doi: 10.3390/ijms22041949. Review. PubMed PMID: 33669361; PubMed Central PMCID: PMC7920320.
Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 Nov 19;80(4):633-647.e7. doi: 10.1016/j.molcel.2020.10.026. PubMed PMID: 33217317; PubMed Central PMCID: PMC7720844.
Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019 Jun 25;10(1):2782. doi: 10.1038/s41467-019-10669-0. PubMed PMID: 31239444; PubMed Central PMCID: PMC6592937.
Robinson M, Shah P, Cui YH, He YY. The Role of Dynamic m6 A RNA Methylation in Photobiology. Photochem Photobiol. 2019 Jan;95(1):95-104. doi: 10.1111/php.12930. Epub 2018 May 24. Review. PubMed PMID: 29729018; PubMed Central PMCID: PMC6309319.
Shah P, Zhao B, Qiang L, He YY. Phosphorylation of xeroderma pigmentosum group C regulates ultraviolet-induced DNA damage repair. Nucleic Acids Res. 2018 Jun 1;46(10):5050-5060. doi: 10.1093/nar/gky239. PubMed PMID: 29660033; PubMed Central PMCID: PMC6007576.
Sample A, Zhao B, Wu C, Qian S, Shi X, Aplin A, He YY. The Autophagy Receptor Adaptor p62 is Up-regulated by UVA Radiation in Melanocytes and in Melanoma Cells. Photochem Photobiol. 2018 May;94(3):432-437. doi: 10.1111/php.12809. Epub 2017 Oct 8. PubMed PMID: 28715145; PubMed Central PMCID: PMC5771989.
Sample A, He YY. Mechanisms and prevention of UV-induced melanoma. Photodermatol Photoimmunol Photomed. 2018 Jan;34(1):13-24. doi: 10.1111/phpp.12329. Epub 2017 Aug 2. Review. PubMed PMID: 28703311; PubMed Central PMCID: PMC5760354.
Qiang L, Sample A, Liu H, Wu X, He YY. Epidermal SIRT1 regulates inflammation, cell migration, and wound healing. Sci Rep. 2017 Oct 26;7(1):14110. doi: 10.1038/s41598-017-14371-3. PubMed PMID: 29074993; PubMed Central PMCID: PMC5658409.
Nakai K, He YY, Nishiyama F, Naruse F, Haba R, Kushida Y, Katsuki N, Moriue T, Yoneda K, Kubota Y. IL-17A induces heterogeneous macrophages, and it does not alter the effects of lipopolysaccharides on macrophage activation in the skin of mice. Sci Rep. 2017 Sep 29;7(1):12473. doi: 10.1038/s41598-017-12756-y. PubMed PMID: 28963556; PubMed Central PMCID: PMC5622065.
Sample A, Zhao B, Qiang L, He YY. Adaptor protein p62 promotes skin tumor growth and metastasis and is induced by UVA radiation. J Biol Chem. 2017 Sep 8;292(36):14786-14795. doi: 10.1074/jbc.M117.786160. Epub 2017 Jul 19. PubMed PMID: 28724634; PubMed Central PMCID: PMC5592660.
Sample A, He YY. Autophagy in UV Damage Response. Photochem Photobiol. 2017 Jul;93(4):943-955. doi: 10.1111/php.12691. Epub 2017 Jan 27. Review. PubMed PMID: 27935061; PubMed Central PMCID: PMC5466513.
Yang S, Qiang L, Sample A, Shah P, He YY. NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance. J Biol Chem. 2017 Feb 24;292(8):3379-3388. doi: 10.1074/jbc.M116.756536. Epub 2017 Jan 12. PubMed PMID: 28082672; PubMed Central PMCID: PMC5336170.
Shah P, Trinh E, Qiang L, Xie L, Hu WY, Prins GS, Pi J, He YY. Arsenic Induces p62 Expression to Form a Positive Feedback Loop with Nrf2 in Human Epidermal Keratinocytes: Implications for Preventing Arsenic-Induced Skin Cancer. Molecules. 2017 Jan 24;22(2). doi: 10.3390/molecules22020194. PubMed PMID: 28125038; PubMed Central PMCID: PMC5361890.
Qiang L, Sample A, Shea CR, Soltani K, Macleod KF, He YY. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis. Autophagy. 2017;13(12):2086-2103. doi: 10.1080/15548627.2017.1380757. PubMed PMID: 28933598; PubMed Central PMCID: PMC5788558.
Zhao B, Shah P, Qiang L, He TC, Budanov A, He YY. Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol. 2017 Jan;93(1):375-381. doi: 10.1111/php.12624. Epub 2016 Aug 12. PubMed PMID: 27463837; PubMed Central PMCID: PMC5272907.
Qiang L, Shah P, Barcellos-Hoff MH, He YY. TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair. Oncogene. 2016 Jun 23;35(25):3293-302. doi: 10.1038/onc.2015.390. Epub 2015 Oct 19. PubMed PMID: 26477308; PubMed Central PMCID: PMC4837109.
Zhao B, Qiang L, Joseph J, Kalyanaraman B, Viollet B, He YY. Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival. Genes Dis. 2016 Mar;3(1):82-87. doi: 10.1016/j.gendis.2015.12.002. Epub 2016 Jan 4. PubMed PMID: 28066797; PubMed Central PMCID: PMC5215801.
Qiang L, Zhao B, Shah P, Sample A, Yang S, He YY. Autophagy positively regulates DNA damage recognition by nucleotide excision repair. Autophagy. 2016;12(2):357-68. doi: 10.1080/15548627.2015.1110667. Epub 2015 Nov 13. PubMed PMID: 26565512; PubMed Central PMCID: PMC4835978.
Ming M, Zhao B, Shea CR, Shah P, Qiang L, White SR, Sims DM, He YY. Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge. J Allergy Clin Immunol. 2015 Apr;135(4):936-945.e4. doi: 10.1016/j.jaci.2014.09.035. Epub 2014 Nov 7. PubMed PMID: 25445829; PubMed Central PMCID: PMC4388755.
Shah P, He YY. Molecular regulation of UV-induced DNA repair. Photochem Photobiol. 2015 Mar-Apr;91(2):254-64. doi: 10.1111/php.12406. Epub 2015 Jan 14. Review. PubMed PMID: 25534312; PubMed Central PMCID: PMC4355264.
Ming M, Soltani K, Shea CR, Li X, He YY. Dual role of SIRT1 in UVB-induced skin tumorigenesis. Oncogene. 2015 Jan 15;34(3):357-63. doi: 10.1038/onc.2013.583. Epub 2014 Jan 20. PubMed PMID: 24441046; PubMed Central PMCID: PMC4104262.
Ming M, Zhao B, Qiang L, He YY. Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response. Photochem Photobiol. 2015 Jan-Feb;91(1):242-7. doi: 10.1111/php.12318. Epub 2014 Aug 12. PubMed PMID: 25039758; PubMed Central PMCID: PMC4294972.
Zhao B, Shah P, Budanov AV, Qiang L, Ming M, Aplin A, Sims DM, He YY. Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells. J Biol Chem. 2014 Dec 26;289(52):35806-14. doi: 10.1074/jbc.M114.595397. Epub 2014 Nov 6. PubMed PMID: 25378405; PubMed Central PMCID: PMC4276849.
Kim Y, He YY. Ultraviolet radiation-induced non-melanoma skin cancer: Regulation of DNA damage repair and inflammation. Genes Dis. 2014 Dec 1;1(2):188-198. doi: 10.1016/j.gendis.2014.08.005. PubMed PMID: 25642450; PubMed Central PMCID: PMC4307792.
Ming M, Han W, Zhao B, Sundaresan NR, Deng CX, Gupta MP, He YY. SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer. Cancer Res. 2014 Oct 15;74(20):5925-33. doi: 10.1158/0008-5472.CAN-14-1308. PubMed PMID: 25320180; PubMed Central PMCID: PMC4203414.
Qiang L, He YY. Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition. Autophagy. 2014 Oct 1;10(10):1864-5. doi: 10.4161/auto.32171. Epub 2014 Aug 13. PubMed PMID: 25126736; PubMed Central PMCID: PMC4198370.
Qiang L, Zhao B, Ming M, Wang N, He TC, Hwang S, Thorburn A, He YY. Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9241-6. doi: 10.1073/pnas.1322913111. Epub 2014 Jun 9. PubMed PMID: 24927592; PubMed Central PMCID: PMC4078859.
Ming M, Qiang L, Zhao B, He YY. Mammalian SIRT2 inhibits keratin 19 expression and is a tumor suppressor in skin. Exp Dermatol. 2014 Mar;23(3):207-9. doi: 10.1111/exd.12323. PubMed PMID: 24438005; PubMed Central PMCID: PMC3957270.
Kim I, He YY. Targeting the AMP-Activated Protein Kinase for Cancer Prevention and Therapy. Front Oncol. 2013;3:175. doi: 10.3389/fonc.2013.00175. eCollection 2013. PubMed PMID: 23875169; PubMed Central PMCID: PMC3711071.
Wu CL, Qiang L, Han W, Ming M, Viollet B, He YY. Role of AMPK in UVB-induced DNA damage repair and growth control. Oncogene. 2013 May 23;32(21):2682-9. doi: 10.1038/onc.2012.279. Epub 2012 Jul 2. PubMed PMID: 22751115; PubMed Central PMCID: PMC3465498.
Zhao B, Ming M, He YY. Suppression of PTEN transcription by UVA. J Biochem Mol Toxicol. 2013 Feb;27(2):184-91. doi: 10.1002/jbt.21451. Epub 2012 Nov 5. PubMed PMID: 23129115; PubMed Central PMCID: PMC3567256.
Qiang L, Wu C, Ming M, Viollet B, He YY. Autophagy controls p38 activation to promote cell survival under genotoxic stress. J Biol Chem. 2013 Jan 18;288(3):1603-11. doi: 10.1074/jbc.M112.415224. Epub 2012 Dec 4. PubMed PMID: 23212914; PubMed Central PMCID: PMC3548470.
Shea CR, He YY. Skin, effects of ultraviolet radiation. In: Dulbecco R, Abelson J, editors. Encyclopedia of human biology 3rd ed. NA: Elsevier; 2013.
Han W, Soltani K, Ming M, He YY. Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis. Cancer Prev Res (Phila). 2012 Sep;5(9):1155-62. doi: 10.1158/1940-6207.CAPR-12-0185-T. Epub 2012 Jul 30. PubMed PMID: 22846842; PubMed Central PMCID: PMC3435459.
Ming M, He YY. PTEN in DNA damage repair. Cancer Lett. 2012 Jun 28;319(2):125-129. doi: 10.1016/j.canlet.2012.01.003. Epub 2012 Jan 18. Review. PubMed PMID: 22266095; PubMed Central PMCID: PMC3326178.
Han W, Ming M, Zhao R, Pi J, Wu C, He YY. Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis. J Biol Chem. 2012 May 25;287(22):18788-95. doi: 10.1074/jbc.M112.363614. Epub 2012 Apr 12. PubMed PMID: 22500024; PubMed Central PMCID: PMC3365774.
Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W, Smart RC, Trempus CS, He YY. PTEN positively regulates UVB-induced DNA damage repair. Cancer Res. 2011 Aug 1;71(15):5287-95. doi: 10.1158/0008-5472.CAN-10-4614. Epub 2011 Jul 19. PubMed PMID: 21771908; PubMed Central PMCID: PMC3148338.
Ming M, Shea CR, Feng L, Soltani K, He YY. UVA induces lesions resembling seborrheic keratoses in mice with keratinocyte-specific PTEN downregulation. J Invest Dermatol. 2011 Jul;131(7):1583-6. doi: 10.1038/jid.2011.33. Epub 2011 Mar 10. PubMed PMID: 21390050; PubMed Central PMCID: PMC3116047.
Han W, Ming M, He YY. Caffeine promotes ultraviolet B-induced apoptosis in human keratinocytes without complete DNA repair. J Biol Chem. 2011 Jul 1;286(26):22825-32. doi: 10.1074/jbc.M111.222349. Epub 2011 May 11. PubMed PMID: 21561856; PubMed Central PMCID: PMC3123050.
Thompson EA, Zhu S, Hall JR, House JS, Ranjan R, Burr JA, He YY, Owens DM, Smart RC. C/EBPα expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPα confers susceptibility to UVB-induced skin squamous cell carcinomas. J Invest Dermatol. 2011 Jun;131(6):1339-46. doi: 10.1038/jid.2011.31. Epub 2011 Feb 24. PubMed PMID: 21346772; PubMed Central PMCID: PMC3418815.
Ming M, Shea CR, Guo X, Li X, Soltani K, Han W, He YY. Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22623-8. doi: 10.1073/pnas.1010377108. Epub 2010 Dec 13. PubMed PMID: 21149730; PubMed Central PMCID: PMC3012476.
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